共查询到20条相似文献,搜索用时 15 毫秒
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Jianjuan Jiang Shaoqing Zhang Zhigang Qian Nan Qin Wenwen Song Long Sun Zhitao Zhou Zhifeng Shi Liang Chen Xinxin Li Ying Mao David L. Kaplan Stephanie N. Gilbert Corder Xinzhong Chen Mengkun Liu Fiorenzo G. Omenetto Xiaoxia Xia Tiger H. Tao 《Advanced materials (Deerfield Beach, Fla.)》2018,30(20)
Precise patterning of polymer‐based biomaterials for functional bio‐nanostructures has extensive applications including biosensing, tissue engineering, and regenerative medicine. Remarkable progress is made in both top‐down (based on lithographic methods) and bottom‐up (via self‐assembly) approaches with natural and synthetic biopolymers. However, most methods only yield 2D and pseudo‐3D structures with restricted geometries and functionalities. Here, it is reported that precise nanostructuring on genetically engineered spider silk by accurately directing ion and electron beam interactions with the protein's matrix at the nanoscale to create well‐defined 2D bionanopatterns and further assemble 3D bionanoarchitectures with shape and function on demand, termed “Protein Bricks.” The added control over protein sequence and molecular weight of recombinant spider silk via genetic engineering provides unprecedented lithographic resolution (approaching the molecular limit), sharpness, and biological functions compared to natural proteins. This approach provides a facile method for patterning and immobilizing functional molecules within nanoscopic, hierarchical protein structures, which sheds light on a wide range of biomedical applications such as structure‐enhanced fluorescence and biomimetic microenvironments for controlling cell fate. 相似文献
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Protein Delivery: Bioinspired Diselenide‐Bridged Mesoporous Silica Nanoparticles for Dual‐Responsive Protein Delivery (Adv. Mater. 29/2018) 下载免费PDF全文
Dan Shao Mingqiang Li Zheng Wang Xiao Zheng Yeh‐Hsing Lao Zhimin Chang Fan Zhang Mengmeng Lu Juan Yue Hanze Hu Huize Yan Li Chen Wen‐fei Dong Kam W. Leong 《Advanced materials (Deerfield Beach, Fla.)》2018,30(29)
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Plasmonic Nanostructures: 3D Nanostar Dimers with a Sub‐10‐nm Gap for Single‐/Few‐Molecule Surface‐Enhanced Raman Scattering (Adv. Mater. 15/2014) 下载免费PDF全文
Manohar Chirumamilla Andrea Toma Anisha Gopalakrishnan Gobind Das Remo Proietti Zaccaria Roman Krahne Eliana Rondanina Marco Leoncini Carlo Liberale Francesco De Angelis Enzo Di Fabrizio 《Advanced materials (Deerfield Beach, Fla.)》2014,26(15):2352-2352
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Plasmonic Nanostructures: Boosting the Performance of Organic Optoelectronic Devices Using Multiple‐Patterned Plasmonic Nanostructures (Adv. Mater. 25/2016) 下载免费PDF全文
Yoon Ho Lee Tae Kyung Lee Inho Song Hojeong Yu Jiwon Lee Hyunhyub Ko Sang Kyu Kwak Joon Hak Oh 《Advanced materials (Deerfield Beach, Fla.)》2016,28(25):4945-4945
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