Melanoma-associated hypopigmentation: where are the antibodies?

The purpose of this study was to compare the changes in the degree of conversion in the various layers of composites after additional heat curing. Four types of composites and three types of inlay ovens were used in this study. Composite was placed in a 4 mm thick Teflon mold and light cured from the top for 60 seconds. Twenty samples were prepared for each composite; 10 of these were additionally heat cured in an inlay oven as the manufacturer recommended. After light curing or light and heat curing, the samples were sectioned into four parts and assigned to groups A, B, C, or D according to their distance from the light source. These sections were then thinned to 50 to 70 mm, and these wafers were analyzed with a Fourier Transform Infrared spectrometer to determine the degree of conversion. A standard baseline technique was used to calculate the degree of conversion. When the composites were heat cured, significant increases in the degree of conversion were noted throughout the samples, but the amount of increase differed among materials. Thus the clinical performance of a heat-treated composite inlay may be different depending on materials.     

EFFECTS OF MATRIX MOLECULAR WEIGHT ON STRUCTURE AND REINFORCEMENT OF HIGH DENSITY POLYETHYLENEfMICA COMPOSITES

Three types of high-density polyethylene (HDPE) with different molecular weights (high,medium and low) were adopted to evaluate the influence of matrix molecular weight on the structure-propcrty relation of injection-molded HDPE/mica composites through a combination of SEM,2d-WAXS,DSC,DMA and tensile testing. Various structural factors including orientation,filler dispersion,interfacial interaction between HDPE and mica,etc.,which can impact the macroscopic mechanics,were compared in detail among the three HDPE/mica composites. The transcrystallization of HDPE on the mica surface was observed and it exhibited strong matrix molecular weight dependence. Obvious transcrystalline structure was found in the composite with low molecular weight HDPE,whereas it was hard to be detected in the composites with increased HDPE molecular weight. The best reinforcement effect in the composite with low molecular weight HDPE can be understood as mainly due to substantially improved interfacial adhesion between matrix and mica filler,which arises from the transcrystallization mechanism.     

Amalgam alternatives--micro-leakage evaluation of clinical procedures. Part I: direct composite/composite inlay/ceramic inlay

This study investigated the degree of dye penetration with three different types of tooth-coloured restorations. Twenty-four intact extracted molars were collected. The teeth were immediately stored in water at room temperature. Class II cavity preparations were prepared and restored with three different types of tooth-coloured restorations: A, composite resin in the incremental technique; B, composite inlay technique; and C, ceramic inlay. Specimens were subjected to 700 cycles of thermal stress. They were than immersed in 2% basic fuchsin dye. The teeth were sectioned in three planes before being ranked as to the amount of dye penetration. The highest score obtained on three plano-parallel sections was adopted as the representative value. The three groups were compared using the Kruskal Wallis non-parametric test. Dye penetration was significantly lower at the enamel margins when using the composite inlay system and the incremental technique compared to the ceramic inlay technique. The restorations placed using the composite inlay technique showed less dye penetration than the incremental technique at the dentine margins (P < 0.017).     

Resin-modified glass ionomers for luting posterior ceramic restorations

OBJECTIVES: Until recently, esthetic inlay restorations in posterior teeth have been limited to cavities surrounded by enamel. Dentin adhesive systems in combination with luting composites and light-cured resin-modified glass ionomer cements offer a possibility for bonding ceramic inlays to cavities when the cervical margin is in dentin. This study was designed to compare in vitro marginal integrity of ceramic inlays bonded to dentin to restorations placed in cavities with margins located entirely in the enamel. METHODS: In the present in vitro study, the sealing abilities of a dentin bonding agent/luting composite combination (Syntac/Dual Cement, Vivadent) and resin-modified glass ionomers (Photac Fil, Photac Bond, ESPE; Dyract, De Trey Dentsply; Fuji II LC, GC Dental Industrial Corp.; and Vitremer, 3M Dental Products) used as luting agents in cavities extending beyond the cemento-enamel junction, were compared to the sealing abilities of a conventional luting composite (Vita Cerec Duo Cement, Vita) in cavities within sound enamel. SEM analysis and dye penetration were performed to evaluate marginal integrity at the cervical cavity margins. RESULTS: The dentin bonding agent/luting composite combination (Syntac/Dual Cement) rendered a marginal seal within the dentin similar to the quality obtained with the conventional luting procedures within sound enamel. When three out of the five resin-modified glass ionomers were used as luting agents (Dyract, Fuji II LC and Vitremer), the results were comparable to those reported for the dentin bonding agents and the conventional method. SIGNIFICANCE: Light-cured resin-modified glass ionomer cements may be considered as an alternative to dentin bonding agents when the cavity margins of ceramic inlay restorations are within the dentin. However, further studies, e.g., wear resistance, must be performed.     

Prevention of intellectual disabilities: early interventions to improve cognitive development

The isothermal enthalpy changes with time of a dental composite were examined by microcalorimetry to isolate the effects of different filler concentrations and curing times on chemical aging of these composites. Urethane dimethacrylate (UDMA) monomer, zirconia-silica (ZS) powder, and 3-methacryloxypropyltrimethoxysilane (MAPM) were used as organic and inorganic matrices, and a coupling agent, respectively. The composite was mixed in different ratios and cured by visible light. The enthalpy changes with time for 0, 15, 45, 75% ZS-filled UDMA and 75% MAPM-silanated ZS-filled UDMA cured for 13, 30, 90, 150, and 300 s were measured at 37.0 degrees, 57.0 degrees, and 65.5 degrees C until equilibrium. Increased curing time and filler concentration caused the excess enthalpy changes (dH) and their rate of change (dH/dt) to increase with annealing time and apparent equilibrium was reached faster. In addition, dH showed nonlinear dependence with the increase in filler concentration by showing a maxima for samples containing 25 wt% filler. Further, filler silanation caused dH/dt to increase and required shorter times to reach apparent equilibrium. dH also reached a minimum when samples contained silanated filler, compared to composites containing unsilanated filler. It was concluded that the shorter curing time caused the occurrence of spontaneous densification, which facilitated continual resin curing; and longer curing time caused higher crosslinking of the organic phase. Moderate concentration of inorganic phase restricts the molecular motion of the surface layer of polymer onto filler particles, and the polymer is regarded as highly crosslinked, while a higher filler concentration forms aggregates that are covered by the polymer which causes a decrease in the molecular packing of the resin, and is reflected as low enthalpy values. Finally, silanation of the filler showed a highly endothermic reaction that is probably due to breaking and forming of bonds at the interface between the organic and the inorganic phases in the composites.     

Mycosis fungoides palmaris et plantaris or acral pagetoid reticulosis?

Direct bonding of brackets has become a routine procedure in clinical orthodontics. Many techniques and materials are currently advocated and used, the most recent being light-cured composites. Advantages of the light-cured systems are their relative ease of use, improved bracket placement, and more rapid set of the composite. For a new system to be clinically viable, it must possess properties that are at least as reliable as existing systems. The purpose of this longitudinal clinical study was to evaluate and compare the rate of success and/or failure between a visible light-cured bonding material (Sequence) and a chemically cured bonding material (System 1+), using both systems in every patient. Contralateral quadrants were bonded with each system respectively. A total of 32 patients were followed for a mean period of 11 months (range of 3 to 21 months), with a total of 531 brackets bonded, 265 with visible light-cured and 266 with chemically cured resins. Failures for each system were recorded and failure rates calculated. The failure rate of the visible light-cured composite was 11.3% and that of the chemically cured composite was 12%. A Chi-squared (chi2) test did not reveal any statistically significant differences between the failure rates of the two systems, (chi2 = 0.014, df-1, P > 0.9).     

Evaluation of mechanical and thermal properties of Poly (butylene terephthalate) (PBT) composites reinforced with wollastonite

Particulate filled polymer composites are becoming attractive because of their wide applications and low cost. Present study deals with the preparation and characterization of PBT/wollastomte composites and analyzing the effect of incorporation of varying concentration of wollastonite on the mechanical, thermal, and morphological properties of PBT thermoplastic composite for future industrial applications. In the composites wollastonite content was varied by 0–30 % by weight. Tensile strength exhibited a marginal increase whereas a dramatic increase was observed in modulus with an increase in filler content. The experimental results were also compared with theoretical predictions which revealed good level of interfacial interaction in the composites. Thermal analysis revealed an increase in percent crystallinity and also the onset crystallization temperature thereby indicating the nucleating efficiency of wollastonite. Study of the fracture surface by SEM revealed a change in the micromechanical deformation process with an increase in filler content.     

Hydroxyapatite-polyethylene composites for bone substitution: effects of ceramic particle size and morphology

Synthetic hydroxyapatite particles of two median sizes and different morphologies have been used to manufacture hydroxyapatite reinforced high density polyethylene composites (HAPEX) for medical applications. The effects of hydroxyapatite particle size on properties of the resultant composites were investigated using various techniques. It was found that composites with smaller hydroxyapatite particles had higher torsional modulus, tensile modulus and tensile strength, but lower strain to failure. Examination of fracture surfaces revealed that only a mechanical bond existed between the filler and the matrix. It was shown that dynamic mechanical analysis is useful in studying the viscoelastic behaviour of the composite.     

铸造钢铁基耐磨复合材料制备工艺的研究进展

评述了铸造钢铁基耐磨复合材料的制备工艺和研究进展,重点分析了双液复合铸造、双金属镶铸及铸渗3种耐磨复合材料制备工艺,并对耐磨复合材料制备技术的未来发展方向和研究重点提出合理选材、提高冶金质量、应用数值模拟技术、探研界面结合机理等建议。     

Investigation of nickel metal powder on tribological and mechanical properties of Al-7075 alloy composites for gear materials

This research paper describes the fabrication of different weight percentages of (0–2?wt-%) nickel powder-filled aluminium alloy composites by stir casting techniques under a controlled environment. The physical, mechanical and tribological analyses of the nickel powder-filled aluminium alloy (Al-7075 series) composites are studied experimentally. The void content, Vickers hardness, compressive strength and impact strength of the unfilled and particulate-filled alloy composites are increased with the increase in filler content, while flexural strength of the composites shows reverse in trend. At the end, sliding wear analysis is performed to assess the wear performance of the unfilled and particulate-filled alloy composites. It is also observed that 2?wt-% nickel powder-filled alloy composite exhibits higher wear resistance as compared to other alloy composites. Finally, the microstructure analysis of the worn out composites is observed through scanning electron microscope to comprehend the wear mechanism of the composites for gear material application.     

Study on Preparation and Property of Poly－Aminosilicone－Rare Earth Composite

The poly-aminosilicone-rare earth composite was prepared by poly-aminosilicone cross-linked with rare earth and active silanol. The thermal stability of the composites was studied by thermogravimetric analysis (TG). Force condition of the composites in electric field was analyzed and relative polarizability was derived. It is found that the composites containing different rare earth ions have different relative polarizability. The experiment results reveal that organosilicon materials with different electrical performance can be obtained by this way. Meanwhile, the absorption and flourescene spectrum of composites were also investigated. Compared to rare earth chloride, the spectrum properties of the composite are changed obviously. The possible reasons for these phenomena were discussed.     

Evaluation of Tribological Performance of PTFE Composite Filled with Rare Earths Treated Carbon Fibers under Water-Lubricated Condition

Carbon fibers （CFs） were surface treated with air-oxidation, rare earths （RE） after air-oxidation, and rare earths, respectively. Erichsen test was conducted to study the interfacial adhesion of PTFE composites filled with carbon fibers treated with different treatment methods. Tribological properties of the PTFE composites, sliding against GCr15 steel under water-lubricated condition, were investigated on a reciprocating ball-on-disk UMT-2MT tribometer. The worn surfaces of the composites were examined using scanning electron microscopy. Experimental results reveal that RE treatment is superior to air oxidation in promoting tribological properties of CF reinforced PTFE （CF/PTFE） composite. The friction and wear properties of PTFE composite filled with RE treated CF are the best of the PTFE composites. RE treatment is more effective than air oxidation to improve the tribological properties of CF/PTFE composite owing to the effective improvement of interfacial adhesion between carbon fibers and PTFE matrix.     

Micro-structural Analysis and Densification Behavior of Al–ZrB<Subscript>2</Subscript> Powder Metallurgy Composite During Upsetting

The performance of the product components in application greatly depends on the morphological parameters and inherent capabilities of the material. In the present study, Al–ZrB₂ composite is made out of powder metallurgy route. Incremental weight% (0, 2, 4 and 6 wt%) of ZrB₂ were added into Al matrix to produce different composites. Composites were prepared by cold axial compaction followed by pressureless sintering at 550 °C for 1 h in controlled atmosphere (Ar gas). Hardness increased with the amount of ZrB₂ in the composite. To enhance the properties further, composites were deformed at 25, 400 and 500 °C respectively. The size, shape and orientation of the grains in the deformed composites were analyzed and correlated with the mechanical properties. The mechanical adhesion of ZrB₂ particle with the Al matrix was examined in different composites during different temperature conditions of deformation process. The fracture strain of the composites decreased with increase of ZrB₂ in the composite.     

Dobutamine maintains intestinal villus blood flow during normotensive endotoxemia: an intravital microscopic study in the rat

OBJECTIVE: This in vitro investigation compared the amount of linear shrinkage that occurs when a light-cured composite resin is cured with a visible light source, and also with an argon laser. SUMMARY BACKGROUND DATA: When composite resins are light-cured, they undergo a certain degree of polymerization shrinkage, which can be clinically significant and affect the efficacy of the restoration. A new protocol utilizes laser curing instead of conventional visible light. METHODS: Two hybrid composite resins were used, Z100 and TPH-Spectrum. Dimensional change was measured in a linear direction, using a calibrated light-microscope. A total of 40 samples of composite resin was tested using two curing lights, and two hybrid composite resins, resulting in four groups of 10 samples (n = 10) each. According to manufacturer instructions, curing time for the laser was 10 sec, and for visible light was 40 sec. RESULTS: With TPH-Spectrum, the mean shrinkage with visible light was 0.583% compared to that with laser light which was 0.591%. With Z100, the mean shrinkage with visible light was 0.565%, compared to that with laser light which was 0.551%. CONCLUSIONS: There was no significant difference in amount of shrinkage of hybrid composite resins between using visible light or laser light. There was also no significant difference in shrinkage between the two hybrid composites for either light source.     

不同钛酸四丁酯含量对GO?TiO2复合材料组织结构和性能的影响

以氧化石墨烯和钛酸四丁酯为原料,采用一步水热法制备氧化石墨烯/二氧化钛（GO?TiO₂）复合材料,研究不同钛酸四丁酯含量对GO?TiO₂复合材料组织和性能的影响规律。通过扫描电镜（SEM）、X射线衍射（XRD）、红外光谱（IR）、拉曼光谱（RS）、紫外?可见分光光度计（UV?vis）、热重分析仪（TGA）等对复合材料的微观形貌、物相组成、结构、吸光性和热稳定性进行表征。研究结果表明,随着钛酸四丁酯含量的增加,有利于GO?TiO₂复合材料的均匀分散,提高了GO?TiO₂复合材料的吸光性和热稳定性,但钛酸四丁酯含量过高会使GO?TiO₂复合材料分散性、吸光性和热稳定性下降。当氧化石墨烯质量为320 mg、钛酸四丁酯含量为100 mL时,反应生成的复合材料表面TiO₂分散均匀,缺陷少,D峰与G峰的峰强比（I_D/I_G）值为0.91,氧化石墨烯和二氧化钛复合程度高,复合材料中的TiO₂吸收边缘红移至可见光范围内,并且在440~800 nm可见光范围内的吸收峰明显增强,防腐防污能力增强,复合材料在800 ℃热稳定性相比于氧化石墨烯提高了84.89%。      

Dual NF1-requiring effect of human neurotropic JC virus composite pentanucleotide repeat elements on early and late viral gene expression

OBJECTIVE: The purpose of this study was to prepare a light-cured adhesive applicable for orthodontics by mixing monomers and a polymerized reactive organic composite filler (prepolymerized trimethylolpropane trimethacrylate-filler, TMPT-filler). METHODS: The monomer component was a mixture of 3.0 wt% 2-hydroxy-3-(2-naphthoxy)propyl methacrylate (HNPM) in triethylene glycol dimethacrylate. This was applied to extracted bovine tooth enamel after acid etching with 65 wt% phosphoric acid for 30 s. After 24 h in 37 degrees C water, the tensile bond strength was measured, and the data were analyzed with Duncan's new multiple range test (p < 0.01 or 0.05). RESULTS: The tensile bonding strength to enamel etched with 65 wt% phosphoric acid was 13.1 +/- 0.5 MPa, and the thermal stability of the bond was excellent. SEM examination of the cross-sectioned specimens modified with HCl demineralization showed that when the diffusion time prior to light irradiation was only 1 min, a well-developed resin honeycomb-like structure was created in the enamel surface in the formulation containing HNPM. SIGNIFICANCE: Monomer impregnation beyond the etched enamel surface was important for resin-enamel bonding, increasing bonding strength and thermal stability. HNPM was effective in enhancing monomer diffusion and impregnation of the etched enamel surface.     

Strain profiles in molars restored with posterior composite resins: effect of cavity size & restorative technique

The objective of the study was to quantitatively compare peak strain in buccal & lingual aspects of human molar teeth restored with composite res in polymers as a function of: 1) cavity size, 2) restorative material, 3) restorative technique. Two composite resin materials were investigated: Herculite (sub micron filler particle) & P 50 (supra micron filler particle). Performance was compared to two different types of high copper amalgams. A total of 48 freshly extracted human molar teeth free from cracks or caries were used. MOD cavities were prepared with three different cavity sizes: 1 mm, 2.5 mm & 5 mm. Rectangular rosette strain gauges were applied centrally on the buccal & lingual surfaces of the prepared teeth. Strain measurements were recorded during subsequent cavity restoration procedures and curing cycles. A comparison of peak strains in the amalgam vs composites using bulk-pack technique showed significantly higher strain in the composite series. Highest strains were noted in the largest cavity size (5 mm). Slot preparation following restoration reduced strains in the composite materials. Subsequent re-filling of the slot increased strain, but still less than the initial value.     

Resistance pattern of middle ear fluid isolates in acute otitis media recently treated with antibiotics

The incorporation of fluoride into restorations is desirable because of its cariostatic action. The purpose of this study was to determine fluoride release and fluoride uptake by enamel and cementum from three visible light-cured fluoride-containing composites. Seven circular discs of each composite were prepared and the amount of fluoride released into distilled water was determined at daily intervals for 14 days and then after 30, 60 and 90 days. The fluoride concentration in enamel and cementum was determined in three successive depths by an acid etch biopsy procedure. The composite slabs were made and ligated to the enamel and cementum surfaces and the teeth were immersed in synthetic saliva for 7 days. After removal of the composite slabs, three successive biopsies were again performed. Then the teeth were immersed in 1 M KOH for 24 h and similar biopsies done. The fluoride concentrations were adjusted to standardized depths of 10microm, and the total and bound fluoride uptake calculated. The amounts of fluoride released were significantly different among the three composites. The fluoride released decreased sharply after 1 day and then gradually reached a plateau. As for the enamel and cementum fluoride uptake, FluorEver showed the largest uptake followed by FluoroCore and then Pertac-Hybrid.     

Contraction gaps in Class II restorations with self-cured and light-cured resin composites

PURPOSE: To evaluate in vitro the cervical gap formation in composite restorations in which an increment of autopolymerizing composite was interposed between the light-cured filling material and the dentin bonding system. Two different self-cured materials and two different adhesives were used and compared. MATERIALS AND METHODS: In 40 Class II cavity preparations with the gingival margins in dentin or cementum, an increment of either of two different autopolymerizing composites, Palfique or Bisfil 2B, was interposed between the light-cured filling material (Palfique Estelite) and either of two different dentin bonding systems, All-Bond and Superbond D (20 restorations each). The specimens were immersed in toluidine blue dye. A section was taken from each specimen and examined under an optical microscope. The extent of dye penetration was measured. The specimens were then stored in water for 1-4 months and replicas of the sections were examined by SEM. RESULTS: Good marginal adaptation was observed for All-Bond/Bisfil 2B in all the restorations. All-Bond/Palfique showed good adaptation in 7 out of 10 cases, the failures occurring between bonding agent and composite. Superbond D/Palfique and Superbond D/Bisfil 2B showed marginal gap formation in 8 out of 10 and in all the restorations respectively. In the latter, four gaps occurred between bonding agent and dentin. As a consequence, a very significant difference (P<0.001) was found between All-Bond and Superbond treatments; no significant difference was found between Bisfil 2B and Palfique in each group treated with either All-Bond or Superbond. After 1-4 months storage in water, hygroscopic expansion of the restorative materials reduced the total number of gaps and the efficacy of the treatments was no more significantly different.     

Effect of Cryo-Ageing at Liquid Nitrogen Temperature and Subsequent Thermal-Annealing on the Interface of Talc Filled Polypropylene with Different Particle Size

Polypropylene (PP) based materials are widely used because of their low cost, good processability and good balance of properties but its low stiffness and strength greatly hinders its even wider utilization. In order to overcome this, PP is reinforced with different fillers. In composites; the issue of interface between the filler and matrix is of importance. Thus in the present paper, the effect of cryo-ageing and subsequent thermal-annealing on the PP-talc filled composites have been studied to monitor its effect on the interface. The composites with talc of different particle sizes are examined for mechanical and structural properties after treatment. The mechanical properties are evaluated by testing its tensile strength and wear performance, whereas, the study of structural properties by FTIR and SEM reveals some structural changes. These results have further been discussed and evaluated to find out the effect of these treatments on interface of various selected talc filled PP composite.