甲壳胺纤维和含银甲壳胺纤维的抗菌性能比较

从定性、定量的角度探讨了甲壳胺纤维和含银甲壳胺纤维对大肠杆菌、金黄色葡萄球菌、枯草芽孢杆菌三种常见的、具有代表性的细菌的抑制作用,并把这两种纤维和粘胶纤维的抗菌性能作了比较。实验结果表明:含银甲壳胺纤维比普通的甲壳胺纤维具有更好的抗菌性能。     

羧甲基甲壳胺纤维对铜离子的吸附性能

为了提高甲壳胺纤维对重金属离子的吸附性能,用氯乙酸对纤维进行改性处理,在纤维的结构中引入羧甲基团后使纤维同时具有能结合重金属离子的胺基和羧酸基团。研究了改性后纤维在不同的改性程度、添加量、时间、温度、pH值等条件下对铜离子的吸附性能。结果表明:羧甲基化改性后的甲壳胺纤维对铜离子有很好的吸附性能。在同样的条件下,未改性的纤维对铜离子的吸附值为41.3mg/g,而改性后的纤维为79.4mg/g。经过羧甲基化改性的甲壳胺纤维对铜离子的饱和吸附容量可以达到148.1mg/g。     

甲壳素和甲壳胺纤维质量的影响因素

概述了影响甲壳素和甲壳胺纤维质量的因素,如甲壳素和甲壳胺的品质、纺丝原液的溶剂选择及浓度的确定、凝固浴的确定;简述了通过化学改性来改善甲壳素和甲壳胺纤维性能;介绍了国内外为改善纤维质量所作的最新研究。     

纺织用甲壳素纤维的研究进展

甲壳素及甲壳胺纤维具有生物可相容性、生物可降解性、无毒性及良好的抗菌性能等特点,已经被应用于纺织服装行业以及医用卫生材料的生产中。介绍了纺织用甲壳素及甲壳胺纤维的制备方法及几个国内外甲壳素纤维品种,分析了甲壳素纤维的应用领域。     

行业动态

二十一世纪新型保健纺织品——甲壳胺纤维随着科学技术的进步和人们卫生保健意识的增强,一种极有发展前途的抗菌、防臭、纯生物保健型纺织品——甲壳胺纤维问世。济南太和生物工程有限公司生产的甲壳胺纤维具有抗菌、除臭、保湿功能。其中含有的甲壳素与皮肤接触时,可刺激体液中杀菌酵素,具有活化组织的功能。因此,该纤维被广泛应用于内衣、运动服、袜子、婴幼儿童装等,日益受到了纺织市场人士的关注。济南太和生物工程有限公司将以热情的服务和高质量的产品使甲壳胺纤维早日走向市场。我国化纤行业2004年度的进出口情况一.化纤进口情况2004…     

新的生物活性纤维素纤维

通过在纺丝液中添加特殊的添加剂或用化学品处理纤维,可使人造纤维素纤维获得生物活性。兰精公司目前的新技术有可能使Tencel和粘胶纤维具有生物活性。用多糖“甲壳胺”纤维改性可以得到生物活性Tencel纤维。在粘胶纺丝液中加入特殊的树脂,可得到具有离子交换性能的纤维。用锌或银离子进一步处理这些纤维,将有可能使粘胶纤维具有生物活性。另外还讨论了纤维的性能、用纤维制成非织造布的可能性以及纤维在非织造布上的潜在应用。     

石墨烯改性腈纶调温纤维的制备及性能表征

石墨烯改性腈纶调温纤维是基于石墨烯、相变微胶囊对腈纶复合改性而得到的具有优良性能的功能纤维。采用掺杂共混的方法,利用湿法纺丝工艺,制备了石墨烯改性腈纶调温纤维,通过对石墨烯、微胶囊乳液以及腈纶调温纤维的表征,分析了纤维的微观形貌、热焓值、抗菌抑菌、远红外温升等性能。结果表明:与普通腈纶相比,石墨烯改性腈纶调温纤维具有智能调温的功能,并且在抗菌抑菌、远红外温升等方面具有优良的性能。     

间接法生产甲壳素纤维

由于天然甲壳素结晶度高,在湿法纺丝过程中溶解甲壳素时需要使用价格较高的有机溶剂。甲壳素脱乙酰基后得到的甲壳胺可以很方便地溶解在稀醋酸水溶液中,经喷丝孔挤出后用稀碱中和沉淀即可得到甲壳胺纤维。在甲壳胺纤维上加上乙酰基后可以得到再生甲壳素纤维。介绍了在用乙酸酐处理甲壳胺纤维制备再生甲壳素纤维过程中,反应时间、反应温度、乙酸酐用量对乙酰化的影响。     

生物质石墨烯改性聚酰胺纤维的制备及性能表征

采用聚合物熔融共混纺丝方法制备含有不同比例的生物质石墨烯的改性聚酰胺复合纤维,通过对其力学性能、远红外性能和抗菌性能的表征,发现随着生物质石墨烯含量的不断增加,复合纤维的力学性能、远红外发射率和抗菌性能得到改善;当生物质石墨烯质量分数为1%时,纤维的抗菌性能达到最佳。     

碱处理对抗菌导湿聚酯纤维性能的影响

讨论了使用碱处理方法对抗菌导湿涤纶进行亲水化改性的影响。用保水率和快干性能对纤维的吸湿、导湿性能的变化进行表征,探讨了碱处理对纤维的表面结构、吸水性、导湿性及抗菌性能的影响。结果表明,随着纤维横截面异形度的变化和碱处理浓度的增加,纤维表面产生微孔,纤维的吸湿性和织物的导湿性能都得到改善。     

The preparation and characterization of chitosan wound dressings with different degrees of acetylation

Chitosan fibers have in recent years found applications in various fields such as antimicrobial textiles and wound dressings. In this study, chitosan fibers with different degrees of acetylation were prepared by controlling the ratio between the amount of acetic anhydride and the weight of the fibers during the acetylation process. The absorption and antimicrobial properties, as well as the dry and wet strength of nonwoven chitosan wound dressings with different degrees of acetylation were studied. Results showed that the partially acetylated chitosan wound dressing had a much higher absorption capacity than the original untreated chitosan samples, while there was a reduction in the wet strength and antimicrobial property for the partially acetylated chitosan nonwoven dressing. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008     

甲壳素与甲壳胺纤维4.纤维在生物医药领域中的应用

甲壳素和甲壳胺是广泛存在于动物和植物中的天然高分子材料。近年来,这两个高分子的生物相容性、生物可降解性、对伤口愈合的促进性能和其它一些优异性能在生物医药领域引起了重视。甲壳素和甲壳胺纤维既具有天然高分子的生物活性,又有纤维材料的特性,在手术缝合线、医用敷料、人工皮肤、硬组织修复材料、人工肾膜、抗菌材料、保健内衣面料、药物缓释等材料中得到了广泛的应用。     

甲壳素与甲壳胺纤维1.纤维的制备

甲壳素和甲壳胺是广泛存在于动物和植物中的天然高分子材料。近年来,这两个高分子的生物相容性、生物可降解性、对伤口愈合的促进性能和其它一些优异性能在科技和工商界引起了广泛的重视。作为一种天然再生资源,它们在许多领域内都有很广的应用和开发潜力。总结了甲壳素和甲壳胺纤维的生产条件。     

The absorption and release of silver and zinc ions by chitosan fibers

When chitosan fibers were treated with AgNO₃ and ZnCl₂ solutions, the silver and zinc ions were chelated by chitosan through the amine groups in the fibers. These novel metal ions can be released into the solution when the silver‐ and zinc‐containing fibers are placed in contact with normal saline. Results showed that the silver‐containing chitosan fibers have good antimicrobial properties, while the zinc‐containing fibers can be used to deliver zinc ions in wound care applications. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 101: 766–771, 2006     

Advances in wound dressing based on electrospinning nanofibers

In recent years, there has been a significant focus on bioactive dressings suitable for treating chronic and acute wounds. Electrospinning nanofibers are considered advanced dressing options due to their high porosity and permeability to air and water, effective barrier properties against external pathogens, and excellent resemblance to the extracellular matrix for wound healing and skin regeneration. This article reviews the recent advancements in the application of electrospinning nanofibers for bioactive wound healing. The review begins with an overview of the wound healing process and electrospinning methods. It then explores the advantages and disadvantages of different synthetic and natural polymers used in the preparation of electrospinning wound dressings. The natural polymers discussed in this review include collagen, gelatin, silk fibroin, chitosan, hyaluronic acid, and sodium alginate. Additionally, the review delves into commonly used synthetic polymers like polyvinyl alcohol, polyvinyl chloride, polyethylene lactone, polylactide, and polyurethane for wound dressing applications. Furthermore, the review examines the blending of natural and synthetic polymers to create high-performance wound dressings. It also explores the incorporation of functional additives, such as antimicrobial agents, growth factors, and natural extracts, into electrospinning nanofibers to expedite wound healing and tissue repair. In conclusion, electrospinning is an emerging technology that provides unique opportunities for designing more effective wound dressings and care products.     

Chitosan/nanocellulose-based bionanocomposite films for controlled betamethasone and silver sulfadiazine delivery

Bionanocomposite films based on chitosan and nanocellulose (nanocrystals or nanofibrils) have gained considerable attention for biomedical applications, especially for wound dressings. However, the development of these films as controlled drug release dressings is still under-exploited. Therefore, this work aimed to design chitosan/nanocellulose-based bionanocomposite films, loaded by betamethasone or silver sulfadiazine, as functional dressings. The films were obtained by solvent casting and characterized by physicochemical, mechanical, barrier properties, in vitro drug release, and antimicrobial activity. The nanocellulose type, physical state, and content caused influence on the film's properties providing different physical, barrier, and drug release profiles. They are semi-occlusive and mechanically resistant; the drug release is controlled, and possesses antimicrobial activity. In conclusion, the developed biodegradable bionanocomposite films are promising as active dressings for controlled drug delivery in the wound site and have specific applications according to their features to treat inflamed and purulent wounds, non-infectious dry wounds, and infectious wounds.     

甲壳素与甲壳胺纤维2.纤维的性能

甲壳素和甲壳胺纤雏既具有纤维材料的强度、桀软性、高表面积和形成各种类型的织物的能力,又有这两种天然高分子所特有的生物相容性、生物可降解性、广谱抗菌性、凝血作用以及促进伤口复愈、调节血脂、降低胆固醇、增强免疫和抗肿瘤等多种生理活性作用。     

Sonochemical Functionalization of Cotton and Non-Woven Fabrics with Bio-Inspired Self-Assembled Nanostructures

Cotton and non-woven fabrics are commonly used for medical applications such as wound dressing. In recent years, there has been a growing interest in developing functionalized fabrics that allow the sustained release of active molecules for large-scale production. However, several limitations of currently used technologies restrict the ability to form durable fabrics with functional coatings. Herein, using a sonochemical process, we successfully deposited diphenylalanine (FF) peptide nanotubes on cotton and non-woven fabrics. FF peptide nanotubes were loaded with curcumin, an antimicrobial and anti-inflammatory agent. The structure of the fabric decorated with nanotubes was studied by electron microscopy, and the sustained release of curcumin was demonstrated using absorbance measurements. Sonication duration was positively correlated with the deposition of the nanotubes onto the fabrics’ fibers as well as the retention of the curcumin within the FF nanotubes. These results suggest that the sonochemical process may be used for large-scale fabrication of functionalized commercial fabrics.     

Studies of Mercaptosuccinic Acid-Crosslinked Chitosan Hydrogel with Grafted Cinnamaldehyde and Silver Nanoparticles for Antibacterial Biomedical Application

For the effective clinical antibacterial application of biomaterials, such as for wound management and tissue repair, the biomaterials need to show proper antibacterial capability as well as non-cytotoxicity. Furthermore, the material needs to have suitable mechanical characteristics for further medical use. Chitosan hydrogel is a potential candidate for various antibacterial biomedical applications due to its amine functionalities that lead to antimicrobial characteristics. Nevertheless, its antimicrobial capability is dependent upon the degree of protonation of amine groups caused by the pH value. Moreover, its mechanical compressive strength may not be high enough for clinical use if not chemically or physically crosslinked. This study utilized a novel chemical crosslinker, mercaptosuccinic acid, to improve its mechanical characteristics. The natural antibacterial agent, cinnamaldehyde, was grafted onto the crosslinked chitosan to improve its antimicrobial capability. Meanwhile, to take advantage of the thiol functionality in the mercaptosuccinic acid, the bactericidal silver nanoparticles were incorporated through silver-thiol covalent bounding. NMR analyses indicated the chitosan was successfully mercaptosuccinic acid-crosslinked and grafted with cinnamaldehyde at different ratios. Combined the results from the mechanical assessment, swelling experiments, antimicrobial assessment, and cytotoxicity assay, the chitosan hydrogel with the highest crosslinked degree and grafted with cinnamaldehyde and silver nanoparticles is of great promise for further clinical uses.