共查询到20条相似文献，搜索用时 15 毫秒
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Marco Lo Presti Maria Michela Giangregorio Roberta Ragni Livia Giotta Maria Rachele Guascito Roberto Comparelli Elisabetta Fanizza Roberto R. Tangorra Angela Agostiano Maria Losurdo Gianluca M. Farinola Francesco Milano Massimo Trotta 《Advanced Electronic Materials》2020,6(7)
A fabrication strategy of photoactive biohybrid electrodes based on the immobilization of the bacterial reaction center (RC) onto indium tin oxide (ITO) is proposed. The RC is an integral photoenzyme that converts photons into stable charge‐separated states with a quantum yield close to one. The photogenerated electron–hole pair can be eventually exploited, with suitable redox mediators, to produce photocurrents. To this purpose, RC must be effectively anchored on the electrode surface and simple strategies for its stable immobilization ensuring prolonged enzyme photoactivity are strongly desired. In this work, polydopamine (PDA), a polymer reminiscent of the natural melanin, is used to anchor the RC on the electrode surface. PDA is easily prepared in situ by spontaneous polymerization of dopamine in slightly alkaline aerated buffered RC solution. This reaction, carried out in the presence of an ITO substrate dipped into the solution, directly leads to a stable RC‐PDA/ITO photoelectrode with 20 nm film thickness and 50% of fully functional RC occupancy. Photocurrents densities recorded using this photoelectrode are comparable to those obtained with far more sophisticated immobilization techniques. The RC‐PDA films are fully characterized by visible–near‐infrared absorption spectroscopy, ellipsometry, atomic force, and scanning electron microscopies. 相似文献
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Bioelectronics: Plasmon‐Enhanced Photocurrent of Photosynthetic Pigment Proteins on Nanoporous Silver (Adv. Funct. Mater. 2/2016) 
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下载免费PDF全文 Vincent M. Friebe Juan D. Delgado David J. K. Swainsbury J. Michael Gruber Alina Chanaewa Rienk van Grondelle Elizabeth von Hauff Diego Millo Michael R. Jones Raoul N. Frese 《Advanced functional materials》2016,26(2):284-284
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Vincent M. Friebe Juan D. Delgado David J. K. Swainsbury J. Michael Gruber Alina Chanaewa Rienk van Grondelle Elizabeth von Hauff Diego Millo Michael R. Jones Raoul N. Frese 《Advanced functional materials》2016,26(2):285-292
In a quest to fabricate novel solar energy materials, the high quantum efficiency and long charge separated states of photosynthetic pigment‐proteins are being exploited through their direct incorporation in bioelectronic devices. In this work, a biohybrid photocathode comprised of bacterial reaction center‐light harvesting 1 (RC‐LH1) complexes self‐assembled on a nanostructured silver substrate yields a peak photocurrent of 166 μA cm?2 under 1 sun illumination, and a maximum of 416 μA cm?2 under 4 suns, the highest reported to date on a bare metal electrode. A 2.5‐fold plasmonic enhancement of light absorption per RC‐LH1 complex is observed on the rough silver substrate. This plasmonic interaction is assessed using confocal fluorescence microscopy, revealing an increase of fluorescence yield, and radiative rate of the RC‐LH1 complexes, signatures of plasmon‐enhanced fluorescence. Nanostructuring of the silver substrate also enhanced the stability of the protein under continuous illumination by almost an order of magnitude relative to a nonstructured bulk silver control. Due to its ease of construction, increased protein loading capacity, stability, and more efficient use of light, this hybrid material is an excellent candidate for further development of plasmon‐enhanced biosensors and biophotovoltaic devices. 相似文献
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Michele Di Lauro Simona la Gatta Carlo A. Bortolotti Valerio Beni Vitaliy Parkula Sofia Drakopoulou Martina Giordani Marcello Berto Francesco Milano Tobias Cramer Mauro Murgia Angela Agostiano Gianluca M. Farinola Massimo Trotta Fabio Biscarini 《Advanced Electronic Materials》2020,6(1)
The photochemical core of every photosynthetic apparatus is the reaction center, a transmembrane enzyme that converts photons into charge‐separated states across the biological membrane with an almost unitary quantum yield. A light‐responsive organic transistor architecture, which converts light into electrical current by exploiting the efficiency of this biological machinery, is presented. Proper surface tailoring enables the integration of the bacterial reaction center as photoactive element in organic transistors, allowing the transduction of its photogenerated voltage into photomodulation of the output current up to two orders of magnitude. This device architecture, termed light‐responsive electrolyte‐gated organic transistor, is the prototype of a new generation of low‐power hybrid bio‐optoelectronic organic devices. 相似文献
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生物光子学与光子生物学 总被引：2，自引：0，他引：2
本文概述了生物光子学及光子生物学的发生、发展及未来发展趋势。当前,一门新兴学科——光子学（Ｐｈｏｔｏｎｉｃｓ）已经产生。国际上一些发达国家对光子学已给予了充分的重视并大力支持光子学及相关技术和产业的发展［１,２］。古老而又充满发展活力的生命科学早在光子学产生的初期就和光子学相互交叉和渗透,促使两门新的边缘学科分支悄然崛起,即生物光子学和光子生物学。前者站在光子学的立场研究生物特性;后者立足于生物学角度来探讨光子学的应用 相似文献
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Recent breakthroughs in bioelectronic devices have stemmed from developments involving nanocomposites. Sepsis, preeclampsia, vascular dementia, and heart disease are serious conditions that will benefit from the continuous monitoring of pulse pressure (PP) and temperature (T) to improve medical insights and care. However, current clinical instruments are bulky, and lacking discreetness, while nanocomposites currently lack measurement accuracy. A thin (<1 mm) electronic skin (e-skin) is developed utilizing nanocomposite micro-caviar (MC), diameter (D) ≈290 µm, based on confined silver nanowire (AgNW) networks and food-grade brown seaweed (BS). MCs are virtually invisible (transmittance >99%) and extremely electromechanically sensitive (gauge factor, G >200). In addition to a considerable temperature coefficient of resistance (TCR) of 4.58 ± 0.95% °C−1 and excellent signal stability, skin-interfaced devices measured cuff-less PP and skin T with an accuracy conducive to clinical instruments. 相似文献
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Patricia Jastrzebska‐Perfect Shilpika Chowdhury George D. Spyropoulos Zifang Zhao Claudia Cea Jennifer N. Gelinas Dion Khodagholy 《Advanced functional materials》2020,30(29)
Neuroelectronic devices are critical for the diagnosis and treatment of neuropsychiatric conditions, and are hypothesized to have many more applications. A wide variety of materials and approaches have been utilized to create innovative neuroelectronic device components, from the tissue interface and acquisition electronics to interconnects and encapsulation. Although traditional materials have a strong track record of stability and safety within a narrow range of use, many of their properties are suboptimal for chronic implantation in body tissue. Material advances harnessed to form all the components required for fully integrated neuroelectronic devices hold promise for improving the long‐term efficacy and biocompatibility of these devices within physiological environments. Here, it is aimed to provide a comprehensive overview of materials and devices used in translational neuroelectronics, from acquisition and stimulation interfaces to methods for power delivery and real time processing of neural signals. 相似文献
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Peter N. Ciesielski Christopher J. Faulkner Matthew T. Irwin Justin M. Gregory Norman H. Tolk David E. Cliffel G. Kane Jennings 《Advanced functional materials》2010,20(23):4048-4054
The long‐term success of photosynthetic organisms has resulted in their global superabundance, which is sustained by their widespread, continual mass‐production of the integral proteins that photocatalyze the chemical processes of natural photosynthesis. Here, a fast, general method to assemble multilayer films composed of one such photocatalytic protein complex, Photosystem I (PSI), onto a variety of substrates is reported. The resulting films, akin to the stacked thylakoid structures of leaves, consist of a protein matrix that is permeable to electrochemical mediators and contain a high concentration of photoelectrochemically active redox centers. These multilayer assemblies vastly outperform previously reported monolayer films of PSI in terms of photocurrent production when incorporated into an electrochemical system, and it is shown that these photocatalytic properties increase with the film thickness. These results demonstrate how the assembly of micron‐thick coatings of PSI on non‐biological substrates yields a biohybrid ensemble that manifests the photocatalytic activity of the film’s individual protein constituents, and represent significant progress toward affordable, biologically‐inspired renewable energy conversion platforms. 相似文献
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Kangze Dong Guangtao Zan Junchen Zhou Farid Manshaii Shu Pu Shanshan Chai Jeong Min Baik Qingsheng Wu Ming Wen Tong Wu Jun Chen 《Advanced functional materials》2024,34(48):2408348
Developing foldable power sources with simple transport and storage remains a significant challenge and an urgent need for the advancement of next-generation wearable bioelectronics. In this study, super-foldable lithium-ion batteries are developed by integrating biomimetic methods, which effectively address the challenges of stress dispersion and mark a breakthrough in the field of super-foldable devices. A synchronous three-level biomimetic coupling technology is introduced and employed a strategy of radial compounding, gel-electrostatic molding, and temperature-programmed co-pyrolysis. This approach allows us to simultaneously prepare a super-foldable multi-level “lotus structure” cathode and a highly compatible super-foldable “peapods” structure anode. Remarkably, even after 500 000 cycles of repeated folding tests, the full battery maintains a high level of capacity stability, and the galvanostatic charge/discharge curves also exhibit a high degree of consistency. Furthermore, this battery can power an LED clock for over 2870 continuous minutes while undergoing in situ dynamic reciprocating folding, highlighting its substantial promise for practical applications. The super-foldable battery represents a full-chain innovation, extending from the super-foldable substrate to the super-foldable electrodes, and culminating in a super-foldable full battery. 相似文献
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We present a universal model for the transient drain current response in organic electrochemical transistors (OECTs). Using equivalent circuits and charge injection physics, we are able to predict the drain current in OECT devices upon application of a gate voltage input. The model is applicable to both plain and membrane-functionalized devices, and allows us to extract useful physical quantities such as resistances and capacitances, which are related to functional properties of the system. We are also able to use the model to reconstruct the magnitude and shape in time of an applied voltage source based on the observed drain current response. This was experimentally demonstrated for drain current measurements under an applied action potential. 相似文献
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Biohybrid microswimmers have recently shown to be able to actively perform in targeted delivery and in vitro biomedical applications. However, more envisioned functionalities of the microswimmers aimed at in vivo treatments are still challenging. A photosynthetic biohybrid nanoswimmers system (PBNs), magnetic engineered bacteria‐Spirulina platensis, is utilized for tumor‐targeted imaging and therapy. The engineered PBNs is fabricated by superparamagnetic magnetite (Fe3O4 NPs) via a dip‐coating process, enabling its tumor targeting ability and magnetic resonance imaging property after intravenous injection. It is found that the PBNs can be used as oxygenerator for in situ O2 generations in hypoxic solid tumors through photosynthesis, modulating the tumor microenvironment (TME), thus improving the effectiveness of radiotherapy (RT). Furthermore, the innate chlorophyll released from the RT‐treated PBNs, as a photosensitizer, can produce cytotoxic reactive oxygen species under laser irradiation to achieve photodynamic therapy. Excellent tumor inhibition can be realized by the combined multimodal therapies. The PBNs also possesses capacities of chlorophyll‐based fluorescence and photoacoustic imaging, which can monitor the tumor therapy and tumor TME environment. These intriguing properties of the PBNs provide a promising microrobotic platform for TME hypoxic modulation and cancer theranostic applications. 相似文献
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Chiara Baldacchini Maria Antonia Herrero Chamorro Maurizio Prato Salvatore Cannistraro 《Advanced functional materials》2011,21(1):153-157
The integration of redox proteins with nanomaterials has attracted much interest in the past years, and metallic single‐walled carbon nanotubes (SWNTs) have been introduced as efficient electrical wires to connect biomolecules to metal electrodes in advanced nano‐biodevices. Besides preserving biofunctionality, the protein–nanotube connection should ensure appropriate molecular orientation, flexibility, and efficient, reproducible electrical conduction. In this respect, yeast cytochrome c redox proteins are connected to gold electrodes through lying‐down functionalized metallic SWNTs. Immobilization of cytochromes to nanotubes is obtained via covalent bonding between the exposed protein thiols and maleimide‐terminated functional chains attached to the carbon nanotubes. A single‐molecule study performed by combining scanning probe nanoscopies ascertains that the protein topological properties are preserved upon binding and provides unprecedented current images of single proteins bound to carbon nanotubes that allow a detailed I–V characterization. Collectively, the results point out that the use as linkers of suitably functionalized metallic SWNTs results in an electrical communication between redox proteins and gold electrodes more efficient and reproducible than for proteins directly connected with metal surfaces. 相似文献
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Lydia M. Mäthger Stephen L. Senft Meng Gao Sinan Karaveli George R. R. Bell Rashid Zia Alan M. Kuzirian Patrick B. Dennis Wendy J. Crookes‐Goodson Rajesh R. Naik George W. Kattawar Roger T. Hanlon 《Advanced functional materials》2013,23(32):3980-3989
Throughout nature, elegant biophotonic structures have evolved into sophisticated arrangements of pigments and structural reflectors that manipulate light in the skin, cuticles, feathers and fur of animals. Not many spherical biophotonic structures are known and those described are often angle dependent or spectrally tuned. White light scattering by the flexible skin of cuttlefish (Sepia officinalis) is examined and how the unique structure and composition of leucophore cells serve as physiologically passive reflectors approximating the optical properties of a broadband Lambertian surface is investigated. Leucophores are cells that contain thousands of spherical microparticles called leucosomes that consist of sulfated glycoproteins or proteoglycans and reflectin. A leucophore containing ≈12 000 leucosome microspheres is characterized three‐dimensionally by electron microscopy and the average refractive index of individual leucosomes is measured by holographic microscopy to be 1.51 ± 0.02. Modeling of the ultrastructural data and spectral measurements with Lorenz‐Mie theory and Monte Carlo simulations suggest that leucophore whiteness is produced by incoherent scattering based upon a randomly ordered system. These soft, compliant, glycosylated proteinacious spheres may provide a template for bio‐inspired approaches to efficient light scattering in materials science and optical engineering. 相似文献
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Ye Zhang Jianxun Ding Baowen Qi Wei Tao Junqing Wang Caiyan Zhao Huisheng Peng Jinjun Shi 《Advanced functional materials》2019,29(34)
Fiber‐based configurations are highly desirable for wearable and implantable biomedical devices due to their unique properties, such as ultra‐flexibility, weavability, minimal invasiveness, and tissue adaptability. Recent developments have focused on the fabrication of fibrous devices with multiple biomedical functions, such as noninvasively or minimally invasively monitoring of physiological signals, delivering drugs, transplanting cells, and recording and stimulating nerves. In this Review, the recent progress of these multifunctional fiber‐based devices in terms of their composite materials, fabrication techniques, structural designs, device‐tissue interfaces, and biomedical applications is carefully described. The remaining challenges and future directions in this emerging and exciting research field are also highlighted. 相似文献
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Saehyuck Oh Janghwan Jekal Jia Liu Jeehwan Kim Jang-Ung Park Taeyoon Lee Kyung-In Jang 《Advanced functional materials》2024,34(41):2403562
Bioelectronic implantable devices are adept at facilitating continuous monitoring of health and enabling the early detection of diseases, offering insights into the physiological conditions of various bodily organs. Furthermore, these advanced systems have therapeutic capabilities in neuromodulation, demonstrating their efficacy in addressing diverse medical conditions through the precise delivery of stimuli directly to specific targets. This comprehensive review explores developments and applications of bioelectronic devices within the biomedical field. Special emphasis is placed on the evolution of closed-loop systems, which stand out for their dynamic treatment adjustments based on real-time physiological feedback. The integration of Artificial Intelligence (AI) and edge computing technologies is discussed, which significantly bolster the diagnostic and therapeutic functions of these devices. By addressing elemental analyses, current challenges, and future directions in implantable devices, the review aims to guide the pathway for advances in bioelectronic devices. 相似文献
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Moran Amit Sagi Appel Rotem Cohen Ian W. Hamley Nurit Ashkenasy 《Advanced functional materials》2014,24(37):5873-5880
Protons and electrons are being exploited in different natural charge transfer processes. Both types of charge carriers could be, therefore, responsible for charge transport in biomimetic self‐assembled peptide nanostructures. The relative contribution of each type of charge carrier is studied in the present work for fibrils self‐assembled from amyloid‐β derived peptide molecules, in which two non‐natural thiophene‐based amino acids are included. It is shown that under low humidity conditions both electrons and protons contribute to the conduction, with current ratio of 1:2 respectively, while at higher relative humidity proton transport dominates the conductance. This hybrid conduction behavior leads to a bimodal exponential dependence of the conductance on the relative humidity. Furthermore, in both cases the conductance is shown to be affected by the peptide folding state under the entire relative humidity range. This unique hybrid conductivity behavior makes self‐assembled peptide nanostructures powerful building blocks for the construction of electric devices that could use either or both types of charge carriers for their function. 相似文献
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Eunkyoung Kim Yi Liu Xiao‐Wen Shi Xiaohua Yang William E. Bentley Gregory F. Payne 《Advanced functional materials》2010,20(16):2683-2694
Electron transfer in biology occurs with individual or pairs of electrons, and is often mediated by catechol/o‐quinone redox couples. Here, a biomimetic polysaccharide‐catecholic film is fabricated in two steps. First, the stimuli‐responsive polysaccharide chitosan is electrodeposited as a permeable film. Next, the chitosan‐coated electrode is immersed in a solution containing catechol and the electrode is biased to anodically‐oxidize the catechol. The oxidation products covalently graft to the chitosan films as evidenced by electrochemical quartz crystal microbalance (EQCM) studies. Cyclic voltammetry (CV) measurements demonstrate that the catechol‐modified chitosan films are redox‐active although they are non‐conducting and cannot directly transfer electrons to the underlying electrode. The catechol‐modified chitosan films serve as a localized source or sink of electrons that can be transferred to soluble mediators (e.g., ferrocene dimethanol and Ru(NH3) 6Cl3). This electron source/sink is finite, can be depleted, but can be repeatedly regenerated by brief (30 s) electrochemical treatments. Further, the catechol‐modified chitosan films can i) amplify currents associated with the soluble mediators, ii) partially‐rectify these currents in either oxidative or reductive directions (depending on the mediator), and iii) switch between regenerated‐ON and depleted‐OFF states. Physical models are proposed to explain these novel redox properties and possible precedents from nature are discussed. 相似文献