Three different modifications of the dead-beat principle in optimum control

The principle of dead-beat control gives a method of optimum control. It is shown that two other optimum control settings, viz,. that, of the minimum sum criterion and that of the minimum integral criterion, are closely related to dead-beat control, The latter has the additional advantage of being optimal regardless of the moment of appearance of the step disturbance.     

On the difficulties involved in the segmentation of pictures

The problem of picture segmentation is widely believed to be practically unsolvable in its more general case formulation. However, as far as the authors know no formal argumentation has yet been given to this belief related to the segmentation problem. This correspondence provides some theoretical aspects of this phenomenon.     

Neural substrates involved in the control of posture

Abstract

This review argues neuronal mechanisms of postural control. Multi-sensory information such as somatosensory, visual, and vestibular sensation act on various areas of the brain so that adaptable postural control can be achieved. Automatic process of postural control, which is termed as postural reflexes including head–eye coordination accompanied by appropriate alignment of body segments, is mediated by the descending pathways from the brainstem. Cooperation of the vestibulospinal, reticulospinal, and tectospinal tracts contributes to this process. On the other hand, walking in unfamiliar circumstance requires cognitive process of postural control, which depends on knowledge of self-body, such as body schema, sense of postural verticality, and body motion in space. Such a bodily cognitive information is produced at the temporoparietal cortex. They are fundamental to sustention of vertical posture and construction of motor programs. The programs then run to execute anticipatory postural adjustment which is appropriate for achievement of goal-directed movements. The basal ganglia and cerebellum may affect both the automatic and cognitive processes of postural control through reciprocal connections with the brainstem and cerebral cortex, respectively. Consequently, impairments in cognitive function in addition to damages in the motor cortex, basal ganglia, and cerebellum may disturb appropriate postural control, resulting in falling.     

Identifying healthcare actors involved in the adoption of information systems

The adoption of information systems in healthcare is no less significant than in any other commercial or caring organisation. The literature on IS adoption in healthcare, makes it clear that the actors involved in the adoption process are almost universally seen as crucial, which matches our research results too. However, how such actors should be identified remains a topic for investigatory work since these are early days in achieving this. We derive and propose a structured method to model how actors might be identified: structured because such a rationale is explicable and such a method is more readily usable when transferred to others. Our structured method, named IGOHcaps, uses a static and then a dynamic step to pull out the individual, group, organisational and human determinants of the critical actors. In this process, the individual actors' differing views emerge which could enable decision-making bodies to produce more robust proposals if they incorporated some of the appropriate views. We discuss the application of IGOHcaps through a hospital case study. While a single case study cannot be a proof, the engagement of the actors was encouraging.     

Identifying trends in hydration behavior for modifications to the hydrophobicity of poly(n-isopropylacrylamide)

Poly(n-isopropylacrylamide), PNIPAM, is a thermo-responsive polymer that has been thoroughly studied for its many applications, such as drug delivery and actuators. Below the lower critical solution temperature (LCST), PNIPAM is well hydrated in the elongated conformation. The transition occuring at the LCST results in a less hydrated collapsed state above the LCST. This volume phase transition is dependent upon the hydration of the polymer and its hydrophobicity. Some research has been done on potential modifications of PNIPAM for applications, but until now there has not been a study of the hydration properties as a function of hydrophobicity. The work presented in this paper applies a Voronoi analysis of the hydration of PNIPAM, as well as PNIPAM with other alkyl substituents. We show from classical MD simulations that increasing hydrophobicity can increase the volume phase change, but there is a lower limit to this trend. Additionally, replica exchange molecular dynamics were conducted on PNIPAM showing a fluctuation between elongated and collapsed states near the LCST.     

Data analytics in health promotion: Health market segmentation and classification of total joint replacement surgery patients

Providing insight into healthcare consumers' behaviors and attitudes is critical information in an environment where healthcare delivery is moving rapidly towards patient-centered care. We apply a two-stage methodology using both supervised and unsupervised machine learning methods to a patient data set from the electronic medical records of an academic medical center located in central Pennsylvania. The data are from patients who had total joint replacement surgery between December 2013 and September 2015. Two clustering methods and four classification algorithms were applied to the data set. Patients cluster into six distinct health market segments from which the cluster assignment is used as the response variable in supervised learning to classify patients. The classification model accurately predicts the cluster assignment for out-of-sample patients, while offering insight into patient behaviors and attributes to help clinicians, health marketers, and healthcare consumers move toward the goal of patient-centered and value-based healthcare.     

Two‐dimensional gel electrophoresis of apolipoprotein C‐III and other serum glycoproteins for the combined screening of human congenital disorders of O‐ and N‐glycosylation

Congenital disorders of glycosylation (CDG) are inherited diseases that can affect not only the N‐glycan (e.g. CDG type I and II) but also the O‐glycan biosynthesis pathway. In the absence of specific clinical symptoms, there is a need for a reliable biological screening of these two groups of CDG. Using a few microlitres of human serum, 2‐DE and immunoblotting were applied to the separation and simultaneous detection of the isoforms of the O‐glycosylated protein apolipoprotein C‐III (apoC‐III) and of four N‐glycosylated proteins, namely alpha‐antitrypsin, alpha‐1 acid glycoprotein, haptoglobin and transferrin. For the study of O‐glycosylation, this technique allowed the reliable separation of the three fractions of apoC‐III and the determination of normal percentage values in an adult population. Concerning N‐glycosylation, the study of serum samples from patients with CDG type Ia revealed marked abnormalities systematically affecting the four 2‐DE separated N‐linked glycoproteins. 2‐DE coupled to immunoblotting using a mixture of specific antibodies could be easily and reliably employed for the combined screening of both N‐ and O‐glycosylation disorders in humans.     

入侵检测系统在涉密计算机中的应用研究

分析了涉密计算机安全防护的意义和要求,并阐述了入侵检测系统(IDS)的基本概念,在此基础上提出了一个将基于主机的入侵检测系统应用于涉密计算机安全防护中的具体方案。该系统是基于代理的,它在对涉密计算机本身的性能几乎没有影响的情况下很大的提高了入侵检测的准确性,从而大大增强了涉密计算机的安全性。     

On the probabilistic-deterministic transition involved in a fragmentation process of brittle materials

Dynamic loadings produce high stress waves leading to the fragmentation of brittle materials such as ceramics, concrete, glass and rocks. The main mechanism used to explain the change of the number of fragments with stress rate is a shielding phenomenon. However, under quasi-static loading conditions, a weakest link hypothesis may be applicable. Therefore, depending on the local strain or stress rate, different fragmentation regimes are observed. One regime corresponds to single fragmentation for which a probabilistic approach is needed. Conversely, the multiple fragmentation regime may be described by a deterministic approach. The transition between the two fragmentation regimes is discussed for high performance concrete, glass and SiC ceramics.     

On the use of compensated total least squares in systemidentification

A bias-compensated total least squares estimator is proposed for models which are linear-in-the-parameters and nonlinear in the perturbed input and output signals. The estimates are obtained using a noniterative and numerically stable method. Strong consistency of both the generalized total least squares and the compensated total least squares estimates are proven. The theoretical properties are verified through simulations     

广西钟山主要水稻土肥力变化浅析

连续十年定位监测结果表明,土壤有机质、钾素养分含量逐年下降,土壤氮素、磷素养分含量则逐年上升.主要原因是有机肥和钾肥投入量少,钾肥施用比例低.钾肥施用比例与作物产量呈极显著正相关,增施钾肥和有机肥是改善水稻土肥力的主要措施.     

PLC5在工业生产制品统计系统中的应用

本文介绍了PLC5在工业生产制品统计系统中的应用及有关特点，给出了PLC5控制系统的硬件说明和软件编程的技巧。     

物联网工程专业中高职院校教学课程实验体系研究

在分析了高校物联网工程专业的培养目标和教学特点的基础上,指出了高校物联网工程专业的课程设置体系和结构,重点对高校物联网工程专业的综合实验教学提出了比较详细的设想。     

On the complexity of signed and minus total domination in graphs

In this paper we present unified methods to solve the minus and signed total domination problems for chordal bipartite graphs and trees in O(n²) and O(n+m) time, respectively. We also prove that the decision problem for the signed total domination problem on doubly chordal graphs is NP-complete. Note that bipartite permutation graphs, biconvex bipartite graphs, and convex bipartite graphs are subclasses of chordal bipartite graphs.