共查询到18条相似文献,搜索用时 125 毫秒
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营养基因组学是高通量基因组技术在日粮营养素与基因组互作及其与健康关系研究中的应用.随着人类和模式动物基因组的阐明以及近年有关技术的进展,同时进行生物样品中DNA,mRNA和表达的蛋白质分析,确定基因的多样性已成为可能.它将加速认识营养如何影响代谢途径和机体稳态控制,发现与营养有关疾病早期调节失控与基因型的关系.应用营养基因组学建立评价营养素利用效率的标识和方法,可为公众健康提供有效的科学依据.利用营养基因组学技术能够提高产品质量与生产效率,促进食品工业发展和开拓新的市场. 相似文献
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本文从营养基因组学的角度综述了膳食与健康的关系.许多生物活性膳食成分能通过影响基因表达来脱毒,预防炎症、慢性疾病和癌症等,极大地促进人类健康.当然,营养基因组学的发展还不成熟,需要大力研究来最终实现基于个体基因型的营养策略,从而用膳食调整来促进居民健康. 相似文献
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以近20年SCI-E(Science Citation Index Expanded)数据库中的期刊论文为研究对象,运用文献计量学方法,分析全球营养基因组学研究现状及发展趋势,为相关科学研究和管理决策提供参考。结果显示:全球营养基因组学领域研究成果总体上呈现波动增长态势,但仍然处于"爬坡"发展阶段,具有巨大发展空间和广阔发展前景;美国及其研究机构在营养基因组学研究的文献数量方面占有绝对优势,中国尚未进入全球主要国家与机构行列;营养与营养学是此领域的第一大研究方向,多学科、跨领域合作研究正成为主流;研究热点向着饮食与健康方向转移,从治疗疾病向预防疾病(保持健康)转变;营养基因组学应用、临床医学、新兴交叉学科、表观基因组缺陷、地中海式饮食等方面是营养基因组学领域的研究前沿。作为世界第一人口大国,中国的营养基因组学研究应得到重视和发展,以满足国民的健康需求和抢占生物医学与健康领域发展制高点。 相似文献
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随着蛋白质组学技术的日益发展和完善,蛋白质组学技术在许多研究领域都得到广泛应用,并取得一系列令人瞩目的研究成果。蛋白质组学技术在营养研究中的应用虽然处于起步阶段,但已经取得可喜进展,并表现出巨大的潜力和发展空间。在营养研究中充分利用蛋白质组学技术平台,将带来新的研究思路和方法,有助于引导营养学研究向新的高度和深度发展。 相似文献
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《Food Reviews International》2013,29(4):326-345
Nutritional research has recently emphasized the role of nutrients on gene expression and regulation. Although not as broadly appreciated, availability of nutrients affects gene expression. The response to a nutrient status seems in many cases to be specific for each genotype and specific nutrient impairment results in altered gene expression, depending on each genotype. Recent literature has suggested that carbohydrates, fatty acids, minerals, and vitamins of all the dietary constituents participate in the regulation of gene expression. Here, we summarize the current knowledge on the role of nutrients on cancer, phenylketonuria, cardiovascular and other life threatening diseases. 相似文献
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The science of nutrigenomics allows us to consider not only the response of our genes, proteins and metabolism to diet but also life‐stage and lifestyle. Public health messages are failing to change people's behaviour and to counteract the flashy advertising promoting cheap nutritionally‐empty foods. Proponents suggest that using the information supplied by nutrigenomics to develop personalised diet and lifestyle regimens would enable consumers to make healthier choices for themselves. For some this will mean accessing new food products and genetic testing but for others it will mean better dietary advice that can be applied in their situation. Opponents argue that this approach merely panders to the worried‐wealthy‐well – those least in need of intervention because they are already diet and health conscious – and that nutrigenomics fails to address the real issues associated with diet‐related disease. Is nutrigenomics another over‐hyped science, which will ultimately disappoint, or is it an ideal tool for nutrition research? Copyright © 2007 Society of Chemical Industry 相似文献
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Jéssica Rosso Motta Ivo Emilio da Cruz Jung Verônica Farina Azzolin Cibele Ferreira Teixeira Luiza Elizabete Braun Daniel Augusto De Oliveira Nerys Marco Aurélio Echart Motano Marta Maria Medeiros Frescura Duarte Ednea Aguiar Maia-Ribeiro Ivana Beatrice Mânica da Cruz Fernanda Barbisan 《Journal of Food Biochemistry》2021,45(2):e13596