Neuropsychological performance and positive and negative symptoms in schizophrenia.

Examined cognitive functions in 11 positive-symptom (mean age 36 yrs), 10 negative-symptom (mean age 33.8 yrs), and 23 mixed-symptom (mean age 31.4 yrs) schizophrenics; 15 bipolar patients (mean age 34.7 yrs); and 12 normal controls (mean age 34.8 yrs) to explore the relation between symptoms and performance. Ss were administered a neuropsychological test battery including the Purdue Pegboard, the Revised Visual Retention Test, and the Block Design subtest of the Wechsler Adult Intelligence Scale—Revised (WAIS—R). Group comparisons revealed generalized deficits in schizophrenics. Positive-symptom schizophrenics scored below normal Ss and negative-symptom Ss on 2 measures tapping verbal memory. Multiple regression analyses revealed that negative symptom ratings were inversely associated with performance on visual-motor tasks, whereas positive symptoms were inversely associated with verbal memory performance. Findings are not consistent with the notion that cognitive deficits are uniquely associated with negative symptoms. Instead, results suggest that there may be specific cognitive correlates of both the positive and negative symptom dimensions. (38 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Speech competence in manic and schizophrenic psychoses: The association between clinically rated thought disorder and cohesion and reference performance.

Compared 20 thought-disordered (TD) manics and schizophrenics (mean age 31 yrs) to 20 manic and schizophrenic patients (mean age 31.25 yrs) without thought disorder (NTD) and to 10 normal Ss (mean age 30.9 yrs) normal on the rating scales of cohesion and reference performance in speech developed by S. R. Rochester and J. R. Martin (1979). TD manics and schizophrenics differed from NTD Ss and the normal group in their more frequent use of unclear references as well as in their less frequent use of effective cohesion and reference strategies. Speech elements of the TD Ss were classified into disordered and nondisordered segments, and the same natural language analysis was completed for each category of speech segments. Nondisordered speech segments of TD Ss were quite similar to the overall speech performance of NTD Ss and the normal group. There were no cohesion or reference performance differences between TD manics and TD schizophrenics in their disordered speech segments. Findings are interpreted as validation of the usefulness of the Rochester and Martin rating system for identifying aspects of speech performance that are related to clinically rated thought disorder. (22 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Defective interhemispheric transfer in schizophrenia.

Groups of schizophrenics, nurses, and psychiatric controls were trained to perform a manual shape discrimination task. The 20 schizophrenics included 17 outpatients and 3 short-term inpatients: 10 males (mean age 36 yrs) and 10 females (mean age 37.6 yrs). Nurse control Ss were 10 male (mean age 26.3 yrs) and 10 female (mean age 22 yrs) psychiatric nurses or student nurses. Psychiatric control Ss were 8 males (mean age 36.1 yrs) and 10 females (mean age 32.6 yrs). On both of the tasks included in the experiment, the schizophrenic group, but not the control groups, displayed defective intermanual transfer. The performances of the schizophrenics resembled those previously obtained with split-brain monkeys on similar tasks; therefore, it is concluded that the schizophrenics tested suffered from incomplete transfer of stereognostic shape information from 1 cerebral hemisphere to the other. Experiments suggesting poor interhemispheric transfer on auditory tasks in schizophrenics are discussed along with the possibility that certain schizophrenic symptoms are related to defective interhemispheric communication. (21 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Residual performance deficit in clinically remitted schizophrenics: A marker of schizophrenia?

The study of remitted schizophrenic outpatients is proposed as a way of minimizing the effects of the "nuisance variables" that confound the study of hospitalized schizophrenics. 20 hospitalized acutely disturbed schizophrenics (mean age, 37.0 yrs), 20 schizophrenic outpatients in clinical remission (mean age, 42.8 yrs) and 20 normal controls (mean age, 35.1 yrs) were administered a span of apprehension test and the Continuous Performance Test (CPT). All Ss were controlled for sex and WAIS scores and schizophrenics were rated with Phillips Prognostic Rating Scale. On the CPT, both acute and remitted schizophrenics made significantly more errors of omission and commission than did the normal controls. On the span of apprehension, both groups of schizophrenics showed a significantly greater decrement in accuracy of detection of the target stimuli than did normal controls. The same pattern of results has been observed in children at risk for schizophrenia, which suggests that the span of apprehension may be sensitive to core schizophrenic processes that are independent of clinical state. The cross-sectional study of the 3 stages of schizophrenia—the premorbid, acute, and remitted—is proposed as a way of identifying "core" schizophrenic processes and markers of vulnerability to schizophrenia. The adequacy of a general "attentional impairment" interpretation of schizophrenic deficit is questioned. (43 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sentence processing in schizophrenic listeners.

40 hospitalized schizophrenics and 40 volunteers from the community (age range for both groups 17-59 yrs) listened to sentences in which a click was embedded. 20 schizophrenic Ss and 20 normal Ss were asked to reproduce the sentences and indicate precisely where the click occurred. The remaining Ss were given the previously heard sentences and asked to recognize the click locations. Results show that schizophrenic Ss tend to be less accurate than normal Ss in locating the clicks. However, this inferior performance was not due to an inability to use syntactic rules. Rather, the pattern of errors demonstrated that schizophrenic Ss distinguish between sentences which are acoustically identical but syntactically distinct, and that this distinction is maintained under response conditions with varying emphases on sentence retrieval. It is concluded that schizophrenics appear to use syntax as a basis for sentence processing at least to the same extent as normal Ss do. (27 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Serial recall by schizophrenic and affective patients during and after psychotic episodes.

Eight schizophrenics (mean age 27.3 yrs), 8 depressed patients (mean age 33.1 yrs), and 8 normal controls (mean age 27 yrs) completed the MMPI and were asked to recall short word strings in both the presence and absence of distraction. Results show a differential cognitive deficit among schizophrenics both before and after a general improvement in their level of adjustment. That is, despite an overall improvement in their accuracy of recall prior to discharge, their performance continued to be impaired relative to depressed and normal Ss on the words presented in the 1st serial position. A tendency toward greater distractibility among schizophrenics failed to reach statistical significance at both points of assessment. Further substantiation of such stable forms of cognitive impairment may facilitate the identification of individuals who are vulnerable to the development of schizophrenia and may shed light on the adjustment problems that many chronic patients continue to experience after discharge from the hospital. (18 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Mnemonic organization and free recall in schizophrenia.

Investigated word-storage structure and processes of organization and retrieval in 17 young schizophrenics (mean age 26.5 yrs) and 13 normal Ss (mean age 25.7 yrs). Ss were required to establish a stable organization of 25 unrelated words through repeated, self-paced sortings into self-determined categories. Subsequently, they were asked for free recall of the words. The schizophrenics required significantly more trials to complete the sorting task, but once this was achieved they recalled as many words in equally regular order as the normals did. The groups did not differ in regard to organizational structure in the sortings as assessed by hierarchical structure analysis. It is concluded that a schizophrenic deficit of mnemonic organization is indicated, possibly due to difficulties in maintaining a stable system of categories. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Representational boundaries in role portrayals among paranoid and nonparanoid schizophrenic patients.

Studied the boundary properties of self and other representations in 31 normal Ss (mean age 18.8 yrs) and in 18 paranoid (mean age 21.2 yrs), 14 intermediate (mean age 21.9 yrs), and 16 nonparanoid (mean age 22.1 yrs) inpatient schizophrenics, using a dramatic role-playing technique. Role test and Rorschach responses were scored for presence of fluid and rigid boundaries between representations of human characters. Paranoid schizophrenics evidenced higher levels of rigid boundaries, nonparanoid schizophrenics had higher levels of fluid boundaries, and normal Ss showed fewer fluid or rigid boundaries. Rorschach and role test measures of boundary disruption were significantly correlated with each other and with other measures of psychopathology. Findings suggest that the relative balance between fluid and rigid representational boundaries is an effective discriminator of paranoid and nonparanoid subtypes and that the presence of either type of boundary imagery discriminates schizophrenics from normal Ss. (31 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Redundancy deficit in the reaction time of normal subjects under standard and meprobamate-impaired conditions.

Assessed latency and redundancy deficit, which reliably show impairment in process schizophrenics, using 20 normal Ss (mean age 30.4 yrs) with no psychiatric history. Ss were tested under standard/optimal and drug-impaired conditions to evaluate whether an expected increase in latency would be accompanied by a correlated increase in redundancy deficit. Ss completed RT trials in which they depressed and released a key in response to slides and a buzzer. Meprobamate was administered for the 2nd series of trials. In other research, the redundancy deficit index has been found to be independent of latency and has shown promise as a marker of schizophrenic information processing difficulty. The present findings confirm the independence of these 2 markers in that no increased redundancy deficit was observed despite a significant increase in latency. Findings also reveal a greater degree of redundancy deficit in normals under the optimal conditions than had been expected. A methodological problem with trial arrangements is discussed, and a review of studies that tested redundancy deficit in normal Ss is presented. (French abstract) (33 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Perceptual grouping in schizophrenia: Replication of Place and Gilmore.

E. Place and G. Gilmore (see record 1980-25819-001) found that schizophrenics, unlike control Ss failed to utilize gestalt grouping principles in a task involving line counting. The present investigation was a replication of that study but with several methodological refinements, including the subtyping of schizophrenics, a fixed exposure duration of 15 msec, and analyses of both raw and arcsin transformed data. Ss were 10 paranoid schizophrenic, 10 nonparanoid schizophrenic, and 10 nonschizophrenic patients (mean age 31 yrs) and 10 normal undergraduates. The basic findings of Place and Gilmore held, and the refinements utilized made no difference. Results are discussed in terms of a 2-stage model of perceptual processing that describes normal perception in terms of an intitial global structuring of the stimulus field and a secondary local analysis. Schizophrenics appear to use the 2nd processing stage regardless of the stimulus condition. (14 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Affect and facilitative self-control: Influence of ecological setting, cognition, and social agent.

Three components of a situation--the ecological setting, the child's cognition, and the social agent--were imbued with positive, neutral, or negative affect to determine if they were functionally related to the continued maintenance of performance at a motor task by 108 1st and 2nd graders. Maintenance of performance is discussed in terms of facilitative self-control, and theoretical linkages to cognitive self-reinforcement and distractibility-frustrative nonreward theories are proposed. The most powerful effects occurred when the affect of the ecological setting was changed: Ss who experienced a happy room (happy pictures and faces) persisted longer than those in the sad or neutral room. Also, Ss who thought about happy things persisted longer than Ss who thought about sad or neutral things, but only when the E acted happy and recently had told the S a happy story. (20 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Expectancies, mood, and performance of depressed and nondepressed psychiatric inpatients on chance and skill tasks.

The learned helplessness model of depression predicts that, compared with nondepressed patients, depressed patients will demonstrate psychomotor deficits, provide lower subjective evaluations of their performance, and perceive reinforcement in skill tasks as more response independent. These predictions were tested in 32 depressed (mean age 35 yrs) and 32 nondepressed (mean age 38 yrs) psychiatric inpatients, who had been administered the Quick Test and the Beck Depression Inventory. Ss performed card- and peg-sorting tasks in which measures of performance, ratings of mood and expectancy of success, and subjective evaluations of performance were obtained under chance and skill reinforcement conditions. Although some support was obtained for the prediction that depressives provide lower evaluations of their performance than nondepressives, the other predictions were not supported. Comparisons between depressed and nondepressed schizophrenics indicate that the mood of depressed schizophrenics was especially sensitive to task outcome for both skill and chance conditions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of discrete emotions on young children's suggestibility.

Two experiments investigated the effects of sadness, anger, and happiness on 4- to 6-year-old children's memory and suggestibility concerning story events. In Experiment 1, children were presented with 3 interactive stories on a video monitor. The stories included protagonists who wanted to give the child a prize. After each story, the child completed a task to try to win the prize. The outcome of the child's effort was manipulated in order to elicit sadness, anger, or happiness. Children's emotions did not affect story recall, but children were more vulnerable to misleading questions about the stories when sad than when angry or happy. In Experiment 2, a story was presented and emotions were elicited using an autobiographical recall task. Children responded to misleading questions and then recalled the story for a different interviewer. Again, children's emotions did not affect the amount of story information recalled correctly, but sad children incorporated more information from misleading questions during recall than did angry or happy children. Sad children's greater suggestibility is discussed in terms of the differing problem-solving strategies associated with discrete emotions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Emotional experience and expression in schizophrenia and depression.

Examined the emotional responses of schizophrenic, depressed, and normal Ss and whether differences in the emotional responding of these groups depended on how emotional responses were elicited or measured. 23 blunted and 20 nonblunted schizophrenics, 17 unipolar depressed Ss, and 20 normal Ss were exposed to a series of affect-eliciting stimuli. The stimuli varied in valence (positive vs negative) and in level of cognitive demand. Ss reported their subjective experiences, and their facial expressions were videotaped. Blunted schizophrenics were the least facially expressive, although their reported subjective experiences did not differ from those of the other groups. The nonblunted schizophrenics were more responsive than the depressed Ss to the positive stimuli, although the 2 groups did not differ in their clinical ratings of affective flatness. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Body-image aberration in schizophrenia.

A 28-item true–false scale was constructed to measure schizophrenic body-image aberration. The scale was standardized on both 631 male and 718 female college students and 100 male noncollege normal controls (mean age 31.7 yrs). The 74 male schizophrenic Ss reported more body-image aberration than normal nonstudent Ss, but only a portion of the schizophrenics were deviant. 20 male nonpsychotic clinic clients did not have heightened scores. Correlational findings indicate that schizophrenic body-image aberration is an aspect of a broader perceptual aberration. Scores on body-image aberration were negatively correlated with time since first hospitalization. The Body-Image Aberration Scale had essentially no correlation with the Physical Anhedonia Scale (L. J. Chapman, J. P. Chapman, and M. L. Raulin) for schizophrenics. For nonschizophrenics, however, high scores on the 2 scales accompanied one another significantly less often than expected by chance. It is suggested that the 2 scales may identify alternative manifestations of proneness toward the same schizophrenia. (42 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Development of a scale to measure intense ambivalence.

Developed a 45-item true–false scale to measure intense ambivalence using a procedure that ensured high internal consistency with minimal method variance. It has been argued that intense ambivalance is characteristic of Ss who are genetically predisposed to the development of schizophrenia. The scale was first validated by interviewing 72 (of 759 Ss who completed the scale) college students who scored high and in the normal range on the scale. Ss who scored high on the scale spontaneously reported feeling ambivalent and behaved ambivalently more often than low-scoring controls. The scale was then given to 85 schizophrenics (mean age 35.6 yrs), 30 hospitalized depressives (mean age 35.5 yrs), 192 psychology clinic patients (mean age 27.1 yrs), and 139 normal controls (mean age 31.3 yrs). As predicted, schizophrenics scored higher than controls; clinic clients scored in the middle range. Depressives scored the highest of all the groups. (40 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Creativity and schizophrenia: An equivalence of cognitive processing.

Two tests of creativity were given to 10 paranoid and 10 nonparanoid schizophrenics, 10 nonpsychotic psychiatric controls, and 10 normal Ss. Ss were aged between 18 and 50 yrs. Scores on vocabulary and similarities tests, as well as education, medication, marital status, socioeconomic background, and age, were examined. Results indicate that nonparanoid schizophrenics were significantly more creative than paranoids and psychiatric controls on one creativity measure, a graded level measure of the Alternate Uses Test. Also, nonparanoid schizophrenics produced a significantly higher percentage of "highly creative" responses than did normals. Nonparanoid schizophrenics also scored higher than the other groups on the Welsh Figure Preference Test, but this finding was found to be related to age rather than to schizophrenia. The superior performance of the nonparanoid schizophrenic is discussed in terms of the encouragement that a supportive, nonjudgmental testing environment provides. (35 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Left-ear superiority in children for processing auditory emotional material.

Investigated hemispheric asymmetries in children for processing auditory material varying in emotional intonation or verbal content. 31 kindergartners, 32 4th graders, and 32 8th graders reported on the emotional content and on the verbal content of dichotically presented sentences. Ss listened to tapes of 4 phrases spoken in tones that were happy, sad, angry, or neutral and to sentences that varied in verbal content only. Ss also completed a handedness questionnaire and a hearing test. All age groups showed a left-ear advantage for reporting on the emotional material and a right-ear advantage for reporting on the verbal material. For the emotional task, the degree of ear asymmetry did not vary significantly as a function of emotional category. Findings indicate the the right hemisphere is specialized for mediating auditory emotional stimuli as early as 5 yrs of age. (45 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Is this happiness I see? Biases in the identification of emotional facial expressions in depression and social phobia.

The present study was designed to examine the operation of depression-specific biases in the identification or labeling of facial expression of emotions. Participants diagnosed with major depression and social phobia and control participants were presented with faces that expressed increasing degrees of emotional intensity, slowly changing from a neutral to a full-intensity happy, sad, or angry expression. The authors assessed individual differences in the intensity of facial expression of emotion that was required for the participants to accurately identify the emotion being expressed. The depressed participants required significantly greater intensity of emotion than did the social phobic and the control participants to correctly identify happy expressions and less intensity to identify sad than angry expressions. In contrast, social phobic participants needed less intensity to correctly identify the angry expressions than did the depressed and control participants and less intensity to identify angry than sad expressions. Implications of these results for interpersonal functioning in depression and social phobia are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Chronic malnutrition and child behavior: Effects of early caloric supplementation on social and emotional functioning at school age.

138 chronically malnourished Ss (aged 6–8 yrs) were observed in social interactions in 6-S groups and administered a battery of cognitive tests, including the Bender-Gestalt. Independent variables were measures of maternal caloric supplementation (CAS) during pregnancy, and child CAS from birth to 2 yrs, and from age 2 to 4. High CAS from birth to 2 yrs predicted high levels of social involvement, both happy and angry affect, and moderate activity level at school age. Low CAS was associated with passivity, dependency on adults, and anxious behavior. These relationships were significant when socioeconomic status and maternal CAS were controlled. Cognitive measures were not strongly predicted by supplement intake. Results indicate the importance of adequate energy intake in infancy for later social–emotional development. (39 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)