Studying the adsorption of DNA nanostructures on graphene in the aqueous phase using molecular dynamic simulations

DNA nanostructures can undergo large structural fluctuations and deviate from their intended configurations. In this work, two model DNA nanostructures (i.e., Nan and Kai) were designed based on the shape of the two Chinese characters of the name of Nankai University, and additional single-stranded DNA fragments were added to interact with graphene. During four 50-ns molecular dynamic simulations in aqueous solution, the DNA nanostructures adsorbed onto graphene demonstrated more stable conformations with lower root mean square deviations and smaller coordinate changes in the z-axis direction than the DNA nanostructures that were not adsorbed onto graphene. The interaction analyses and energetic calculations show that π-π interactions between single-stranded DNA and graphene are necessary for adsorption of the DNA nanostructures. Overall, this work examined the interactions between DNA and graphene at a large spatial scale with the hope that it provides a new strategy to stabilize DNA nanostructures.     

Automated analysis of tethered DNA nanostructures using constraint solving

Implementing DNA computing circuits using components tethered to a surface offers several advantages over using components that freely diffuse in bulk solution. However, automated computational modeling of tethered circuits is far more challenging than for solution-phase circuits, because molecular geometry must be taken into account when deciding whether two tethered species may interact. Here, we tackle this issue by translating a tethered molecular circuit into a constraint problem that encodes the possible physical configurations of the components, using a simple biophysical model. We use a satisfaction modulo theories solver to determine whether the constraint problem associated with a given structure is satisfiable, which corresponds to whether that structure is physically realizable given the constraints imposed by the tether geometry. We apply this technique to example structures from the literature, and discuss how this approach could be integrated with a reaction enumerator to enable fully automated analysis of tethered molecular computing systems. This paper is a significantly revised and extended version of a conference publication: Lakin and Phillips (in Brijder and Qian (eds) Proceedings of the 23rd International Conference on DNA Computing and Molecular Programming. Lecture Notes in Computer Science, vol 10467, pp 1–16, 2017).     

Vibrational control of nonlinear systems: Vibrational stabilizability

In this work, the theory of vibrational control for nonlinear systems is developed. The present paper gives criteria for stabilizability of nonlinear systems by linear multiplicative vibrations, by almost periodic forcing and by vector additive vibrations. Illustrative examples are also considered. In a subsequent paper, the problem of vibrational controllability and transient behavior will be addressed.     

Studies on contact resistance in graphene based devices

Contact resistance is an important limiting factor for the on-state current of graphene based devices. In this paper, both transmission line method and four-probe method are applied to measure the contact resistance in graphene-metal (Cr/Au and Ti/Au) interface. The calculated contact resistivity values by both methods are concentrated at 10⁴ Ωμm². These two methods are compared and four-probe method showed higher stability. At last, the graphene-Ti/Au devices are annealed at 400 °C with argon and hydrogen gas flow. After annealing, the contact resistivity values are reduced to 10³ Ωμm².     

Parallel-packaged multiple-gas microsensors based on hollowed nanostructures of doped tin oxides

Microsystem Technologies - Hollow nanofiber multiple-gas microsensors containing a ceramic package in parallel were developed via doping metal oxides in tin oxide (SnO2) and electrospinning and...     

基于电化学还原氧化石墨烯的电化学DNA生物传感器

使用还原氧化石墨烯(rGO)制备一种简单、快速和可重复方法构建DNA生物传感器。将带负电的氧化石墨烯(GO)与半胱氨酸上带正电的氨基基团通过静电作用相互吸附,用线性扫描伏安法(LSV)电化学还原电极表面吸附的GO。将二茂铁标记的DNA(Fc-DNA)探针固定到r GO表面,成功构建DNA传感器。传感器的制备过程使用循环伏安法和拉曼光谱表征。通过杂化前后DNA传感器所展现出方波信号峰电流的差异,实现对目标DNA的定量检测。实验结果表明:目标DNA浓度在1. 0×10~(-13)～1. 0×10~(-6)mol/L范围内,峰电流变化与目标DNA浓度呈线性关系,线性相关系数为0. 981,检测限是2. 0×10~(-13)mol/L (S/N=3)。     

基于石墨烯晶体管的多巴胺检测微流控芯片

设计并制备了一种集成液体栅极的石墨烯场效应晶体管的微流控芯片,利用其对多巴胺进行检测,研究了多巴胺分子对石墨烯场效应管转移特性的影响。将石墨烯转移到载玻片上作为导电通道和传感材料集成在微流通道内部,利用剥离(lift-off)工艺制作晶体管的源极和漏极,采用液体栅极的方法对晶体管的转移特性进行测试。同时,结合微电子学的能带理论,从电子迁移的角度出发,讨论了石墨烯和多巴胺之间的氧化还原反应。并采用金属Pt电极作为石墨烯晶体管的栅极,检测到了1 nmol/L浓度的多巴胺溶液。     

基于Pt/石墨烯纳米复合材料的甲醛电化学传感器

采用电沉积的方法制备了Pt/石墨烯纳米复合材料,考察了该复合材料的电化学性能,用于甲醛的检测,表现出良好的检测性能.实验结果表明:在0. 1 mol/L的H2 SO4 溶液中,Pt/石墨烯纳米复合材料修饰电极可以实现在2 ×10 -6 ~2 ×10-3 mol/L浓度范围内甲醛浓度的检测,最低检测限为1 ×10-6 mol/L,并且具有高的灵敏度和良好的重现性.     

石墨烯气体传感解吸附特性研究

分析探讨了石墨烯气体解吸附特性与解吸附方法。通过实验分析石墨烯对NO2气体分子的响应时间、气体分子解吸附时间,分析探讨石墨烯的气敏特性。实验表明,石墨烯对NO2气体传感灵敏度高,响应快,但恢复过程缓慢,气体解吸附时间长。分析表明,通过加热的方法、光照的方法可有效减少石墨烯气体解吸附时间,改善解吸附特性。     

Vibrational control of nonlinear systems: Vibrational controllability and transient behavior

In the first part of this work [1], the criteria for the existence of stabilizing parametric oscillations have been derived. In the present paper, the problem of choosing the stabilizing vibrations is addressed and the properties of transient behavior of vibrationally controlled nonlinear systems are analyzed.     

Thermal vibration analysis of embedded graphene oxide powder-reinforced nanocomposite plates

In this research, thermal vibration analysis of a graphene oxide powder-reinforced (GOPR) nanocomposite embedded plate is carried out once the plate is exposed to different types of thermal...     

Numerical analysis of single-layered graphene sheets by a mesh-free approach

The paper presents a numerical analysis of the behavior of single-layered graphene sheet (SLGS) using a mesh-free approach based on a nonlocal continuum plate model (NCPM). The adopted NCPM constructed by incorporating the nonlocal elasticity theory into the first order shear deformation elastic plate theory is able to capture small length scale effects. Through the NCPM, the SLGS is modeled as a continuous orthotropic nanoplate. the obtained nonlocal nonlinear partial differential equations completed by boundary conditions are solved numerically by a mesh-free approach associating the asymptotic numerical method with the mesh-free collocation method based on moving least square approximation. The effects of the small-scale parameter and aspect ratio on the nonlinear bending and post-buckling behaviors of SLGS are considered. Good agreement has been established between the obtained results and those of the literature.

     

Plasmonic holographic nanostructures

Surface plasmon resonance (SPR) in planar nanostructures is considered. SPR-based methods of measuring optical characteristics and thicknesses of nanolayers are given. Use of diffraction and holographic gratings comprised of small sub-gratings displaced perpendicular to the grooves is considered to achieve the fine structure of plasmonic resonance and more accurate measurements.     

High-performance liquefied petroleum gas sensing based on nanostructures of zinc oxide and zinc stannate

Toxic and combustible gas detection plays a major role in environmental air quality monitoring. Real-time monitoring of hazardous gases and signal of accidental leakages is of great importance owing to the concern for safety requirements in industries and household applications. A simple and economical method for the fabrication of highly sensitive zinc oxide (ZnO) nanorods based gas sensors for detecting low concentrations of Liquefied Petroleum Gas (LPG) was studied in this work. Platinum (Pt) nanoparticles were deposited on the sensing medium which acts as catalysts to improve the sensor performance. The change in electrical resistance of the metal oxide semiconductor for varying concentrations of LPG was measured. Maximum response of 59% was achieved for 9000 ppm LPG at 250 °C. Further to improve the sensing performance of the sensor towards LPG, surface modification of ZnO nanorods using zinc stannate (Zn₂SnO₄) microcubes was performed. High response of 63% was observed for 3000 ppm LPG at 250 °C. Significant improvement in response of the sensor with Zn₂SnO₄ microcubes on ZnO nanorods was observed when compared to sensor with ZnO nanorods.     

Reconfigurable frequency and steerable beam of monopole antenna based on graphene pads

This article presents a reconfigurable frequency and steerable beam monopole antenna based on tunable graphene pads operating in both 4G and 5G bands. The proposed antenna consists of printed CPW‐fed circular monopole shapes, with five rectangular strips added with a separation angle of 45°. These strips are connected to monopole by using graphene pads. The monopole antenna operates in the lower 5G band from 3 up to 7.8 GHz at ?6 dB reflection coefficient. The antenna has an omni‐radiation pattern over the operating band without any applied bias voltage to the graphene pads. By applying the DC bias voltage, the rectangular strips are connected to the monopole and the designed antenna start to resonate from 1.8 to 8 GHz adding the 4G band frequencies. The steering of the proposed antenna beam started from ?60° to 60° according to the bias of the connected graphene pads. The graphene pad exhibits a variable resistance realizing an almost short to an open circuit with and without voltage bias, respectively. The designed antenna is simulated using high frequency structure simulation (HFSS) Ansys ver. 19 and equivalent circuit model of the graphene. The antenna is fabricated using reduced graphene oxide (RGO) pads. Reflection coefficient and radiation pattern measurements as well as simulations are presented with a positive agreement between the results.     

The effect of concentration on gas sensor model based on graphene nanoribbon

Graphene nanoribbon (GNR), a superior material with two-dimensional structure and monolayer honeycomb of carbon, is noteworthy and important in all fields’ mainly electronic, chemistry, biology, physics and nanotechnology. Recently, observing about sensors demonstrates that for better accuracy, faster response time and enlarged sensitivity, it needs to be improved. Nowadays, carbon-based equipments as an exclusive substance are remarkable in the sensing technology. High conductivity as unique properties caused that graphene can be used in biological applications. Gas sensor based on graphene can be supposed to have great sensitivity for gas molecules detection. In this study, graphene-based carbon dioxide sensor analytically is modeled. In addition, new methods of gas sensor model based on the gradient of GNR conductance are provided. Also, a field effect transistor-based structure as a modeling platform is suggested. Ultimately, optimum model is evaluated by comparison study between analytical model and experimental performance.     

Silicon photovoltaic cell based on graphene oxide as an active layer

Microsystem Technologies - This paper presents the fabrication and characterization of spin coated multilayer graphene oxide/p-silicon heterojunction solar cell. Liquid graphene oxide is...     

基于氧化石墨烯和不规则金纳米颗粒的吗啡传感器的研制

该文按照Hummers方法制备出氧化石墨,然后在水中进行超声,剥离出氧化石墨烯.利用氧化石墨烯、不规则的金纳米颗粒和壳聚糖修饰玻碳电极制成电化学传感器,并将其用于海洛因代谢物吗啡的直接电化学测定.考察了pH、工作电位等条件对传感器测定吗啡的影响.结果表明在电位为0.70 V条件下该传感器检测吗啡的线性范围为1.0×10...     

Vibrational analysis and formation mechanism of typical deep eutectic solvents: An experimental and theoretical study

Deep eutectic solvents (DESs), as ionic liquid analogues for green solvents, have gained increasing attentions in chemistry. In this work, three typical kinds of DESs (ChCl/Gly, ChCl/AcOH and ChCl/Urea) were successfully synthesized and characterized by Fourier transform infrared spectroscopy (FTIR) and Raman. Then comprehensive and systematical analyses were performed by the methods of density functional theory (DFT). Two methods (B3LYP/6-311 + +G(2d,p) and dispersion-corrected B3LYP-D3/6-311 + +G(2d,p)) were employed to investigate the structures, vibrational frequencies and assign their ownership of vibrational modes for the DESs, respectively. Nearly all the experimental characteristic peaks of IR and Raman were identified according to the calculated results. By linear fitting of the combined calculated vs experimental vibration frequencies, it can be found that both of the two methods are excellent to reproduce the experimental results. Besides, hydrogen bonds were proved to exist in DESs by IR spectrum, structure analysis and RDG analysis. This work was aimed at predicting and understanding the vibrational spectra of the three typical DESs based on DFT methods. Moreover, by comparing experimental and theoretical results, it provides us a deep understanding of the formation mechanisms of DESs.