Phenomenology of adolescent inhalant intoxication.

Although volatile substance inhalation is prevalent in many contexts and presents a serious threat to public health, this pernicious form of substance misuse remains poorly understood. The question of why people seek and misuse inhalants may be addressed by examining phenomenological accounts of inhalant intoxication, yet few investigations of inhalant intoxication experiences are reported in the literature. This investigation employed a structured interview to assess inhalant intoxication experiences of 267 low-, moderate-, and high-frequency inhalant users. Low-frequency inhalant users reported predominately hedonic experiences during inhalant intoxication, whereas high-frequency users reported a mixture of hedonic and aversive experiences. Aversive experiences such as depressed mood, suicidal ideation, and chest pain were commonly reported by high-frequency users but were relatively rare among low-frequency users. High-frequency users also experienced significantly more euphoria, talkativeness, and grandiosity during inhalant intoxication than low-frequency users. Hedonic and aversive experiences during episodes of inhalant intoxication are relatively common among high-frequency adolescent inhalant users. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Acculturation, Familism, Parental Monitoring, and Knowledge as Predictors of Marijuana and Inhalant Use in Adolescents.

The authors investigated relationships between marijuana and inhalant use and several cultural and demographic factors in Anglo American and Hispanic American adolescents (N=1,094). Outcome measures assessed lifetime and 30-day marijuana and inhalant use. Predictors and covariates used in logistic regression analyses were region, grade, gender, knowledge, acculturation, familism, and parental monitoring. Hispanic Americans exhibited higher usage across all measures. In this group, high acculturation was associated with low marijuana, but high inhalant, use. Across all participants, positive family relations and parental monitoring were strongly associated with attenuated marijuana use hut only among those most knowledgeable about drugs. Familism and monitoring were not associated with diminished usage among the less knowledgeable. For inhalants, monitoring combined with high knowledge or high familism was associated with diminished usage. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Traumas and other adverse life events in adolescents with alcohol abuse and dependence

OBJECTIVE: Clinical observation suggests that adolescents with alcohol use disorders often have complex histories that include childhood maltreatment and other traumas. The aim of this study was to determine the relationships among adolescent alcohol use disorders and a broad range of traumas and adverse life events. METHOD: The subjects were 132 adolescents with alcohol dependence, 51 adolescents with alcohol abuse, and 73 adolescents recruited from the community as a control group. Trauma history was assessed by a semistructured interview and other adverse life events by questionnaire. RESULTS: Traumatic events reflecting interpersonal violence had occurred in many of the adolescents with alcohol dependence and abuse and few of the control adolescents. Adolescents with alcohol abuse or dependence, compared with control subjects, were 6 to 12 times more likely to have a physical abuse history and 18 to 21 times more likely to have a sexual abuse history. Sexual abuse was more common in females, and victimization by other violent acts was more common in males. Many other adverse life events were also significantly more common in the alcohol use disorder groups than in the control group, including having a close friend die, arguments within the family, and legal difficulties. CONCLUSIONS: These results demonstrate that trauma and other adverse life events are strongly associated with alcohol use disorders in adolescents. Clinical screening of adolescents with alcohol use disorders for a range of traumatic events is recommended.     

Gambling, substance use, and impulsivity during adolescence.

This study tested whether problem gambling and substance use in adolescents are related and whether they could have a common link with impulsivity. A community sample of 765 adolescents participated. Gambling and substance use were assessed when adolescents were 17 yrs old. Impulsivity and impulsivity-related behaviors were assessed when adolescents were 12, 13, and 14 yrs old. Groups of gamblers and groups of substance users were formed, A comorbid group was also formed. Results indicated that problem gamblers were more at risk of also being problem substance users and vice versa than nonproblem participants. In addition, comorbid participants were more impulsive than problem gamblers only or problem substance users only. These findings are discussed in light of the possibility that problem gambling and substance use develop simultaneously during adolescence and share a common impulse-control deficits origin. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

NIDA technical review: nitrite inhalants

Nitrite inhalants are commonly abused substances in the US and Europe. "Nitrite inhalants and AIDS" was a popular topic in the early 1980s when the cause of AIDS was not known. With the discovery of HIV, concern about nitrite use wained. However, nitrite inhalant use is associated with behavioral relapse and HIV transmission among gay men, with decreased lymphocyte counts and natural killer cell activity in laboratory studies, and remains a candidate "cofactor" in the pathogenesis of AIDS-related Karposi sarcoma. Discouraging nitrite use continues to be a worthwhile public health goal. Participants recommend specific research efforts.     

Protein solution structure calculations in solution: solvated molecular dynamics refinement of calbindin D9k

Data were collected on the drinking behavior of 415 pregnant adolescents from 1990 to 1994. The relationships between knowledge and attitudes about drinking and drinking behavior were examined. Knowledge about drinking was not related to average daily volume of alcohol before or during pregnancy. Those with specific knowledge about fetal alcohol effects drank less before pregnancy, and in the first trimester, and were also less likely to drink to intoxication. Among drinkers, general knowledge about drinking was significantly related to a decrease in drinking between pre-pregnancy and first trimester, as well as between first and third trimesters. Those with more intolerant attitudes about drinking drank less before and during pregnancy. They had fewer episodes of binge drinking, intoxication, negative consequences, and problem drinking during pregnancy. They were more likely to decrease drinking from the first to third trimesters. These relationships are relevant to developing effective education programs for the high-risk group of pregnant teenagers who drink.     

Desire for help among drug-using Mexican-American arrestees

In a sample of 88 drug-using Mexican-American arrestees, we examined demographic factors, drug-problem severity indicators, and personal and social resources as correlates of self-reported desire for help with problems related to drug use. Ethnicity-related attitudes, perceptions, and experiences were among the factors tested. Among 35 potential correlates in this dataset, recognition of drug-related interpersonal problems was the sole significant correlate of desire for help in a multivariate regression analysis. This finding was interpreted in comparison to previously identified correlates of Mexican-American drug users' desire for help specifically in the form of drug user treatment. We derive implications regarding drug-use-associated problem recognition and other potential determinants of help-seeking and success in drug user treatment among Mexican-American drug users.     

Behavioral factors affecting HIV prevention for adolescent and young adult IDUs

Epidemiological and sociobehavioral data regarding HIV-related risk and injection drug use among adolescents and young adults are examined to provide insight and assistance to nurses delivering preventive intervention and community and clinical care. The increase in HIV/AIDS cases among injection drug users (IDUs), adolescents, and African Americans strongly suggests that clinical care providers acquire a better understanding of the sociocultural and behavioral context within which health care is provided. Transition into injection drug use, high-risk injecting and sexual behaviors, sociodemographic differences, and the importance of social networks are discussed. Nurses are encouraged to provide health promotion, disease prevention messages, and health care to IDUs in small nontraditional clinical settings and to seek out the assistance of the IDUs' social network to increase adherence and compliance to complex prevention and therapeutic efforts.     

Patterns of adolescent involvement in problem behaviors: relationship to self-efficacy, social competence, and life events

Using a sample of 556 adolescents from a suburban community, patterns of various adolescent problem behaviors (e.g., delinquent behavior, smoking, use of alcohol or drugs) and their links to self-efficacy, social competence, and life events were examined. Cluster analysis was conducted to identify four subgroups of adolescents who showed distinct patterns of problem behaviors. These clusters were compared on the measures of self-efficacy, social competence, and life events. Overall results suggest there are meaningful links between adolescents' problem behavior patterns and self-efficacy, the amount and quality of participation in various after school activities, and life events. For example, a subgroup of adolescents who showed uniformly low prevalence of all problem behaviors reported more positive academic self-efficacy, more active participation in sports and nonsports activities, more positive life events, and fewer negative events than adolescents who were involved in multiple problem behaviors. Implications for prevention and future research on adolescent problem behaviors are discussed.     

American Indian adolescent inhalant use

Inhalant use and use patterns, decision-making pertaining to inhalant use, cognitive capacity, cognitive egocentrism, and adherence to traditional ways were studied in a sample of male and female American Indian adolescents residing in a boarding home. Significant differences were not found for gender. Inhalant use group differences were found for only one variable, participation in tribal activities. For males, cognitive ability, cognitive egocentrism and participation in tribal activities were significant predictors of inhalant use/non-use. For females, tribal activities was the only significant predictor.     

Depression and HIV disease in injection drug users: A Spanish language feasibility study.

Developed and tested a mood management intervention to assess its feasibility and effect on mood, drug use, and high-risk behaviors related to HIV in Spanish-speaking injection drug users. Ss were 35 Latino patients at a San Francisco methadone maintenance clinic, 11 of whom agreed to participate. From pretest and posttest interview data, difference scores were computed and analyzed between the participating and nonparticipating comparison groups. The study demonstrated the feasibility of short-term cognitive-behavioral interventions with this Spanish-speaking sample. Results suggest that the intervention moderated the depressive symptoms of the participants, including the HIV positive individuals. No significant changes were found in drug use and HIV-related high-risk behaviors. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Condom Use Among High-Risk Adolescents: Testing the Influence of Alcohol Use on the Relationship of Cognitive Correlates of Behavior.

The goal of this study was the exploration of distal effects of alcohol use on condom use. Criminally involved adolescents completed an initial measure of attitudes, beliefs, and prior behavior. Of the 300 who completed the initial measurement, 267 (89%) completed a behavioral assessment 6 months later. Analyses validated a theoretical model of condom use intentions and indicated that intentions and attitudes measured at baseline were significant predictors of condom use behavior 6 months later. Neither alcohol use nor alcohol problems moderated relationships among model variables or the influence of intentions and attitudes on behavior. The findings do not support a distal role for alcohol use in altering the cognitive correlates of condom use intentions and behavior among high-risk adolescents. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The Drug Involvement Scale for Adolescents (DISA)

This article specifically addressed the need for a multidimensional approach to measuring adolescents' drug involvement. The Drug Involvement Scale for Adolescents (DISA) was theoretically specified and its measurement properties were tested using Confirmatory Factor Analyses and traditional procedures with 705 high-risk and typical high school students. Five first-order dimensions, Drug Access, Alcohol Use, Other Drug Use, Drug Use Control Problems and Adverse Drug Use Consequences, and a hierarchical model of Drug Involvement demonstrated a good fit between model and data. Further, the DISA demonstrated good internal consistency (alpha = .91); correlated as expected with known correlates of adolescent drug use; discriminated drug involvement between high-risk and typical high school students; and predicted later drug involvement and known drug-related consequences among adolescents. The results suggest the DISA should be useful for capturing a multidimensional view of adolescent drug involvement in both etiologic and prevention studies. A major advantage of the DISA is its brevity: twenty-two indicators constructed from twenty-nine items.     

Sexual risk profiles of delinquent and homeless youths

Relatively little is know about the sexual behaviors of high-risk adolescents, such as delinquent and homeless youths. Having secured data from medical examinations, this study provides sexual risk profiles for a sample of delinquent (N = 245) and homeless (N = 160) youths in San Francisco, California. The study found several indicators of high-risk behaviors, such as high levels of STDs, trading sex for money or drugs, and unprotected sexual relations with multiple partners. The study suggests that communities provide better sex education and medical services to high-risk adolescents through multi-service health clinics, public health clinics, and street outreach.     

Does solitary substance use increase adolescents' risk for poor psychosocial and behavioral outcomes? A 9-year longitudinal study comparing solitary and social users.

This longitudinal study compared Grade 8 solitary cigarette smokers (n = 541), drinkers (n = 577), and marijuana users (n = 148) with adolescents who restricted their use of these substances to social settings (ns = 562, 1,426, and 388, respectively) on adolescent functioning and young adult outcomes. In Grade 8, solitary users held more positive beliefs about the consequences of substance use, earned poorer grades, engaged in more deviant behavior, and devoted less time to school and more time to social activities. By age 23, these solitary users had lower educational attainment, poorer self-rated health, and greater substance use problems. Results indicate the importance of better understanding and addressing the needs of this understudied group of high-risk youth. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Substance use and sexual risk taking among Black adolescents and White adolescents.

Analyses of data from a random sample of 1,259 sexually active adolescents revealed that substance use was associated with increased sexual risk taking on 2 occasions of intercourse (1st intercourse ever and 1st intercourse with most recent partner), even after controlling for demographic, experiential, and dispositional confounders. Within-persons analyses yielded similar results, indicating that adolescents who used substances, on 1 of the 2 occasions, reported higher levels of risk taking on the occasion when substances were used than on the no-substance-use occasion. However, substance use was both more common and more strongly linked to risk taking among White than Black adolescents, suggesting that White adolescents are at greater risk of negative consequences related to substance use proximal to intercourse. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Psychosocial factors associated with the initiation of cocaine use among marijuana users.

A short-term prospective design was used to investigate factors associated with the initiation of cocaine use during a 1-year period among a population sample of 942 marijuana users. In addition to demographic items, variables pertaining to various psychosocial characteristics including psychiatric symptoms, personality attributes, social support, and peer pressure were examined. Using cocaine nonusers as a comparison group, male gender, risk-taking tendencies, and socializing with friends on streets or in cars were identified as significant predictors of initiation. Implications for primary prevention programs include redirecting early sensation-seeking tendencies in children and adolescents toward more positive behaviors. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Recent-onset ecstasy use: Association with deviant behaviors and psychiatric comorbidity.

Background: Despite increases in ecstasy (MDMA) use in the United States, little is known about characteristics linked with recent-onset ecstasy use, especially psychiatric symptoms and deviant behaviors. Aims: To test whether individuals with high levels of other drug use are more likely to be recent-onset ecstasy users; to test whether psychiatric symptoms in adults are associated with recent-onset ecstasy use; to explore the association between recent-onset ecstasy use and concomitant deviant behaviors in adolescents and adults. Methods: Data from the 2001 National Survey on Drug Use and Health. Findings: Recent-onset ecstasy use was significantly more likely to occur among adolescents and adults (18-34 years old) who engaged in deviant behaviors during the past year as compared with those who did not engage in deviant behaviors during the past year. Higher levels of deviancy indicated a higher likelihood of being a recent-onset ecstasy user, and associations were strongest with nonviolent deviant behaviors such as selling illegal drugs and stealing. Associations between deviant behaviors and recent-onset ecstasy use were similar in strength to associations between deviant behaviors and recent-onset cocaine and marijuana use, respectively. Adults who had past-year psychiatric symptoms (both depressive and panic symptoms) were twice as likely to be recent-onset ecstasy users as compared with those without past-year psychiatric symptoms. Greater levels of drug involvement increased the odds of being a recent-onset ecstasy user. Conclusion: Recent-onset ecstasy use seems to be associated with a range of other behavioral problems and may reflect one aspect of a larger problem behavior syndrome. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Attachment, motivations, and alcohol: Testing a dual-path model of high-risk drinking and adverse consequences in transitional clinical and student samples.

The purpose of this study was to replicate and extend a motivational model of high-risk drinking and alcohol-related consequences (Cooper, Frone, Russell, & Mudar, 1995; Read, Wood, Kahler, Maddock, & Palfai, 2003), testing the notion that attachment is a common antecedent for both the affective and social paths to problem drinking, defined in terms of 2 dimensions; high-risk drinking and alcohol-related consequences. First-year university students (N = 696), and first-time clients at an addiction treatment facility (N = 213) completed questionnaires assessing alcohol use, alcohol-related consequences, drinking motives, and attachment style. Results underscored the importance of the affective path to drinking patterns and to vulnerability to problems. Results also found that those with higher levels of attachment anxiety were more vulnerable to experiencing adverse consequences related to their drinking. These findings emphasise the importance of attachment styles as a risk factor for high-risk drinking and experiencing alcohol-related consequences. (PsycINFO Database Record (c) 2010 APA, all rights reserved)