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我国植物提取物的应用现状及发展策略 总被引:1,自引:0,他引:1
《医药中间体及其化工原料》2004,(3):26-28
天然药物(包括植物药、动物药)和生物工程药已成为21世纪最热门的药物。一方面,随着社会的发展,人类疾病谱已悄然发生改变,医疗模式已由单纯的疾病治疗转变为预防、保健、治疗、康复相结合的模式,各种替代医学和传统医学正在发挥着越来越大的作用,人类“回归自然”的呼声越来越高,使传统医药倍受青睐。另一方面,我国加入WT0组织后,中国医药市场融入国际医药市场的广度和深度将进一步增加。 相似文献
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植物成分化妆品在近年来备受关注,因其自然和绿色的特点而受到广大消费者的喜爱。本论文旨在综述植物成分化妆品的研究进展,包括植物成分的应用和其功效等方面。通过文献综述,发现越来越多的研究探索了各种植物提取物在化妆品中的应用,如花卉提取物、植物油和植物精华等。这些植物成分在化妆品中具有抗氧化、抗皱、美白和保湿等功效。此外,还总结了植物成分化妆品研究进展的挑战和未来发展方向,如提高植物成分的稳定性和有效性,并进行更深入的安全性评估。期望对今后开发植物成分化妆品提供一些参考。 相似文献
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随着临床医学,基础医学的发展及环境医学和社会医学的崛起,医学模式已由疾病为中心模式向群体、保健、预防和主动参与为特点的以病人为中心的生物、心理、社会的综合治疗模式转变,这种转变给医务工作者提出了更高的要求,更广泛、更人性化的职业内容。而要适应这种特定的职业,完成其特定的职业责任,必须建立一个良好的医患关系。 相似文献
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随着生活水平的不断提高,医疗模式的转变,人们越来越关注自己的健康,体检已成为人们保健的重要手段,亦为发现亚健康人群的重要渠道。越来越多的人群加入体检的行列。但在静脉采血过程中往往发生一些问题,通过一系列努力,投诉率,并发症发生率,护士的消极性都大大的明显降低。 相似文献
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由于现代社会经济的快速发展,医学模式的转变和系统化优质护理服务的开展,患者对护理服务质量提出了更高的要求。要求医护人员把护理工作从单纯的技术操作,扩展到患者的心理、精神、环境、社会等因素的影响作用。 相似文献
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郭雅婧 《中国石油和化工标准与质量》2019,(4)
随着现代社会和科学技术水平的不断提高,现代生物技术发展越来越快速,特别是在医学中的发展非常迅速,成果也十分显著,还具有十分良好的发展优势和前景。笔者首先阐述了现代生物技术,进而对其在医学中的疾病预防、诊断、治疗以及药物制造中的应用进行上相关的分析和研究,并从中了解到现代生物技术对医学领域有着非常重要的意义。 相似文献
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A general multiperiod linear optimization model is proposed in this study that targets the simultaneous design and operation planning decisions of a multiproduct batch plant for the production of vegetable extracts. A multiperiod environment is considered because of the market and/or seasonal fluctuations. Thereby, the model considers changes from period to period of demands, costs, prices and raw materials supplies. The objective function maximizes the net present value of the profit considering incomes, investments and resources costs, and both product and raw material inventory costs. In the plant design problem, the sequence of operations is already defined and the pursued goal is to determine both unit sizes and its configuration in the plant. Besides the usual duplication in parallel option, a novel design alternative is included which allows adding units in series to perform a given operation. The optimal design is determined by taking into account available discrete sizes of units which corresponds to the real procurement of equipments. The model is formulated by using the linear generalized disjunctive programming (LGDP). A particular plant that produces oleoresins (solvent extracts of herbs and spices) is used to illustrate the proposed approach. Nevertheless, the developed model is general and can thus be applied to any vegetable extraction process. 相似文献
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Anna Merecz-Sadowska Przemysaw Sitarek Joanna Stelmach Karolina Zajdel Ewa Kucharska Radosaw Zajdel 《International journal of molecular sciences》2022,23(23)
The kingdom of plants as a “green biofabric” of valuable bioactive molecules has long been used in many ailments. Currently, extracts and pure compounds of plant origin are used to aid in pigmentation skin problems by influencing the process of melanogenesis. Melanin is a very important pigment that protects human skin against ultraviolet radiation and oxidative stress. It is produced by a complex process called melanogenesis. However, disturbances in the melanogenesis mechanism may increase or decrease the level of melanin and generate essential skin problems, such as hyperpigmentation and hypopigmentation. Accordingly, inhibitors or activators of pigment formation are desirable for medical and cosmetic industry. Such properties may be exhibited by molecules of plant origin. Therefore, that literature review presents reports on plant extracts, pure compounds and compositions that may modulate melanin production in living organisms. The potential of plants in the therapy of pigmentation disorders has been highlighted. 相似文献
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Stimuli from the plant Camellia japonica that influence the host-finding and acceptance behaviors of adult females of the generalist herbivore Epiphyas postvittana were investigated. In a binary choice test in a small (35-cm-diam.) arena, females discriminated between a plant and a laminated card model, laying many more eggs on the plant. Observations of females showed that the greater number of eggs laid on the plant were primarily due to on-plant behaviors, with females spending significantly more time per visit on the plant than on the model. Interestingly, females landed a similar number of times on the plant as on the model, suggesting that volatile chemicals from the plant did not influence host-finding. This observation was further supported by wind-tunnel studies, in which females showed little or no upwind flight activity in response to plants and laid similar numbers of eggs on upwind and downwind plants. Leaf surface texture, a combination of smoothness and fine structure (consisting of the midvein and other raised leaf veins), was found to stimulate egg laying by females. Methanol, dichloromethane, and pentane extracts were made of the waxes on the leaf surface. Of these three extracts, only the nonpolar (pentane) one stimulated egg laying by females. Although we did not find a role for volatile plant chemicals in host finding, they appeared to stimulate increased egg laying when the female was on the plant. It appears likely that these chemical and tactile stimuli in C. japonica are general stimuli, which may be found in a large number of plants and, in combination with the feeding preferences of the larva, may explain the generalist herbivorous nature of this pest. 相似文献
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Curčić MG Stanković MS Mrkalić EM Matović ZD Banković DD Cvetković DM Dačić DS Marković SD 《International journal of molecular sciences》2012,13(2):2521-2534
The aim of this study is to examine the growth inhibitory effects of methanolic leaf and fruit extracts of L. vulgare on HCT-116 cells over different time periods and their synergistic effect with a Pd(apox) complex. The antiproliferative activity of plant extracts alone or in combination with the Pd(apox) complex was determined using MTT cell viability assay, where the IC(50) value was used as a parameter of cytotoxicity. Results show that antiproliferative effects of L. vulgare extracts increase with extension of exposure time, with decreasing IC(50) values, except for 72 h where the IC(50) values for methanolic leaf extract were lower than for the fruit extract. The Pd(apox) complex alone had a weak antiproliferative effect, but combination with L. vulgare extracts caused stronger effects with lower IC(50) values than with L. vulgare extracts alone. The type of cell death was explored by fluorescence microscopy using the acridin orange/ethidium bromide method. Treatments with plant extracts caused typical apoptotic morphological changes in HCT-116 cells and co-treatments with Pd(apox) complex caused higher levels of apoptotic cells than treatment with plant extracts alone. The results indicate that L. vulgare is a considerable source of natural bioactive substances with antiproliferative activity on HCT-116 cells and which have a substantial synergistic effect with the Pd(apox) complex. 相似文献
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In phytophagous insects, experience can increase positive responses towards non-host plant extracts or induce oviposition
on non-host plants, but the underlying chemical and behavioral mechanisms are poorly understood. By using the diamondback
moth, Plutella xylostella, its host plant Chinese cabbage, and a non-host plant Chrysanthemum morifolium, as a model system, we observed the experience-altered olfactory responses of ovipositing females towards volatiles of the
non-host plant, volatiles of pure chemicals (p-cymene and α-terpinene) found in the non-host plant, and volatiles of host plants treated with these chemicals. We assessed
the experience-altered oviposition preference towards host plants treated with p-cymene. Naive females showed aversion to the odors of the non-host plant, the pure chemicals, and the pure chemical-treated
host plants. In contrast, experienced females either became attracted by these non-host odors or were no longer repelled by
these odors. Similarly, naive females laid a significantly lower proportion of eggs on pure chemical-treated host plants than
on untreated host plants, but experienced females laid a similar or higher proportion of eggs on pure chemical-treated host
plants compared to untreated host plants. Chemical analysis indicated that application of the non-host pure chemicals on Chinese
cabbage induced emissions of volatiles by this host plant. We conclude that induced preference for previously repellent compounds
is a major mechanism that leads to behavioral changes of this moth towards non-host plants or their extracts. 相似文献
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ubo Ninanský Denisa Osinov Roman Kuruc Alexandra Hengerics Szab Andrea Szrdov Marin Masr
ofia Ninansk 《International journal of molecular sciences》2022,23(24)
Biologically active taxanes, present in small- to medium-sized evergreen conifers of various Taxus species, are widely used for their antioxidant, antimicrobial and anti-inflammatory effects, but mostly for their antitumour effects used in the treatment of solid tumours of the breast, ovary, lung, bladder, prostate, oesophagus and melanoma. More of the substances found in Taxus plant extracts have medical potential. Therefore, at the beginning of this review, we describe the methods of isolation, identification and determination of taxanes in different plant parts. One of the most important taxanes is paclitaxel, for which we summarize the pharmacokinetic parameters of its different formulations. We also describe toxicological risks during clinical therapy such as hypersensitivity, neurotoxicity, gastrointestinal, cardiovascular, haematological, skin and renal toxicity and toxicity to the respiratory system. Since the effect of the drug-form PTX is enhanced by various Taxus spp. extracts, we summarize published clinical intoxications and all fatal poisonings for the Taxus baccata plant. This showed that, despite their significant use in anticancer treatment, attention should also be focused on the risk of fatal intoxication due to ingestion of extracts from these plants, which are commonly found in our surroundings. 相似文献
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Kier D. Klepzig Eugene B. Smalley Kenneth F. Raffa 《Journal of chemical ecology》1996,22(8):1367-1388
This study considered how host plant allelochemicals may contribute to defense against insects and fungi that jointly colonize the subcortical tissues of trees, the relative roles of constitutive and inducible chemistry in these defenses, and how the actions of two different feeding guilds might be interrelated. Our model consisted of the coniferous treePinus resinosa, the root- and lower stem-colonizing beetlesHylastes porculus andDendroctonus valens, and their associated fungiLeptographium procerum andL. terebrantis, and the stem-colonizing bark beetleIps pini and its associated fungusOphiostoma ips. In a novel bioassay, extracts from reaction tissue elicted by wound inoculation withL. terebrantis were more repellent to beetles than were similar extracts from constitutive or mechanically wounded tissue. The effect on beetle behavior was more pronounced in nonpolar extracts, which contain mostly monoterpenes, than in polar extracts, which contain mostly phenolics. Synthetic monoterpenes at concentrations present in the various tissues exerted similar effects and were likewise repellent in dose-response experiments. Growth ofL. procerum andL. terebrantis was inhibited by polar extracts from constitutive and reaction tissue. Inhibition was higher in wounded than control tissue, but the inhibition response did not vary with the type of wounding. Synthetic monoterpenes strongly inhibited spore germination and mycelial growth of both fungi. Colonization of red pine roots byLeptographium spp. altered the subsequent effects of extracts of stem phloem tissue onI. pini. These effects varied with host condition. Beetles preferred extracts from constitutive stem phloem tissue of healthy trees to that of root-diseased trees. However, extracts from reaction tissues of healthy trees were more repellent toI. pini than were the reaction tissues of root-diseased trees. The implications of these results to plant defense against insect-fungal complexes and interactions among different feeding guilds are discussed. 相似文献