分子印迹技术对反季水果中痕量物质的检测

分子印迹技术是近年来发展的一门边缘分支学科,广泛的应用在医药、环境、食品、军事等领域。反季水果在种植期间会施撒一些化学物质进行除草、施肥等,除此之外,反季水果还有"非正常"的加入化学物质进行增产、催熟以及保鲜等。因此利用分子印迹技术对于反季水果中痕量物质的检测有利于减小其对于身体造成的危害,此种方法具有很好的应用前景。     

离子迁移谱(IMS)在环境污染物检测中的研究进展

环境污染问题日趋严重,为了对环境污染物进行检测,必须研究高灵敏度的检测手段,IMS的特点决定了其非常适合对环境污染物中的痕量物质进行检测。由于目前IMS在环境污染检测方面的应用尚属起步阶段,本文主要介绍了国外目前应用IMS检测环境污染的研究进展,以期对IMS在国内的研究和发展起到一定的借鉴作用。     

一种新的绿色化学技术:超临界萃取作为样品制备技术在痕量药检分析中的应用

综述了超临界萃取作为样品制备技术在痕量药检分析中的应用.研究了生物基质对有效萃取目标检测物的影响及提高萃取率的途径.并重点评述了减少类脂杂质、选择性的分离目标检测物的非在线吸附剂收集与在线吸附剂收集技术.从而展示了SFE作为绿色化学技术具有萃取率高、使用溶剂少,分离步骤少,环境无害等明显优于传统方法的特点.     

中国化学学会议消息

今年下半年由中国化学会组织的专业学术会议有:1.“农副产品综合化学会议”主要为玉米、薯类的化学深加工问题,时间8月中旬,地点吉林公主岭。2.“电子材料化学会议”,主要为有机基电子材料与加工中的化学问题,时间9月,地点上海。3.“微量技术及痕量分析学术讨论会”,包括微痕量技术论文交流和方向讨论,时间9月,地点武汉。4.“特种应用化学专题讨论会”,主要为毒物、毒剂及有害化学物质微量分析、检测     

探讨痕量分析实验室污染控制措施

依据CNAS-CL10：2012检测和校准实验室能力认可准则在化学检测领域的应用说明,通过讨论痕量分析实验室的影响因素及解决措施,探讨痕量分析对实验室的要求.     

健全生态环境监测量值溯源体系探讨

简述生态环境监测量值溯源现状，总结在仪器管理、仪器检定校准过程和仪器检定校准方法上存在的不足，提出加强量值溯源体系监管、加快研究和制订或修订生态环境监测仪器的计量技术规范、强化计量保障能力、提升痕量及超痕量污染物监测数据质量、有效建立在线及自动监测仪器设备量值溯源体系等健全生态环境监测量值溯源体系的建议。     

美国研发出新型纳米材料

美国科学家研发出一种人造纳米材料,将这种材料同探测疾病的免疫分析方法相结合,将大大改进癌症等疾病的早期探测情况。免疫分析方法主要通过模拟免疫系统的行为来探测生物标签(与疾病有关的化学物质)在样本内的分布情     

浊点萃取技术的应用

浊点萃取技术(Cloud point extraction,简称CPE)是近年来出现的一种新兴的环保型液-液萃取技术,它以表面活性剂的浊点现象为基础,通过改变实验参数(如溶液的pH值、温度等)引发相分离,作为测定环境样品中痕量金属离子的前处理手段,在分离和富集痕量金属离子方面起着重要作用.     

一种新的绿色化学技术：超临界萃取作为样品制备技术在痕量药检分析中的应

综述了超临界萃取作为样品技术在痕量药检分析中的应用。研究了生物基质对有效萃取目标检测物的影响及提高萃取率的途径。并重点评述了减少类脂杂质、选择性的分离目标检测物的非在线吸附剂收集与在线吸附收集技术。从而展示了ＳＦＥ作为绿色化学技术具有萃取率高、使用溶剂少,分离步骤少,环境无害等明显优于传统方法的特点。     

生物法去除污水中内分泌干扰物的研究现状

内分泌干扰物是一类能够影响人类和动物生殖发育的化学物质.水环境中内分泌干扰物的存在对人类的身体健康存在潜在性危害.近年来,在多个污水处理厂的进水中均检测到了内分泌干扰物.生物处理是有效去除该种类物质的方法之一.分析和综述了内分泌干扰物生物去除方法的主要工艺、作用机理和影响因素,提出了目前存在的主要技术难点和未来研究发展...     

Application of hand-held mobility spectrometers as sensors in manufacturing industries

Ion mobility spectrometers (IMS) are small, lightweight, extremely robust devices with low power requirements, no moving parts, no absolute requirement for gases or vacuums, that can be operated at ambient temperatures and pressures, and yet are capable of measuring vapour phase concentrations of organic chemicals at very low levels (sub-μg/l). IMS are capable of analysing complex mixtures and producing a simple spectral output. Volatile components produce measurable negative and positive product ions in the spectrometer through chemical ionization. The spectra produced are essentially the vapour phase fingerprints of the target molecules/mixture. Quantitative data can be obtained provided instrument response is within the linear dynamic range of these instruments, but most practical applications of IMS have used the technology in a qualitative manner in situations which require just an above/below threshold or positive/ negative response.In the manufacturing industry there are many examples where the aroma/odour of raw materials has safety or product quality implications. IMS was not developed to replace traditional methods of analysis, e.g. GC/MS or sensory panels, but rather to provide a rapid, qualitative response complementary to more established methods. This paper reports on the use of a hand-held ion mobility spectrometer to characterize the vapours produced by volatile organic compounds,fresh herbs and retail spice mixtures at ambient temperature and pressure. The results show that by monitoring in both ion acquisition modes, ion mobility spectrometers are capable of discriminating between a wide range of products.     

易制毒化学品管理与检测

根据《易制毒化学品管理条例》和《中华人民共和国禁毒法》,由工作实践中发现易制毒化学品的日常管制中出现的问题,说明加强易制毒化学品检测的重要性。并介绍了离子迁移谱这种检测技术在易制毒化学品的检测和稽查中发挥的作用。     

对现行食用盐国家标准检测方法的探讨

随着我国加入WTO之后越来越多食用盐检测标准的出现,我国食用盐检测如何与国际标准接轨,如何借鉴和吸收国际先进的检测方法,成为现阶段食用盐检测行业需要考虑的问题。从几项主要指标的检测方法入手,讨论了国内和国际标准的不同,比较了其优缺点,为食用盐国家标准检测方法的改进提供了参考。     

全膜法水处理工艺在制药行业中的应用

全膜法水处理工艺是将"超滤—反渗透—EDI"三种膜分离的技术相组合,达到高效去除污染物以及深度脱盐的目的,以制备高纯水。该工艺可代替原有离子交换树脂脱盐工艺,为制药行业制备符合要求的纯水,且相比旧工艺具有系统运行稳定、对环境污染小、全自动运行、可靠性强等优点,实现高性能、高效率、低成本的处理效果。以实际应用的长期运行数据来验证全膜法应用在制药行业的可行性及优势。     

铁改性海泡石的研制及稳定性研究

用5% FeCl3溶液对海泡石进行改性,制得铁改性海泡石(Iron Modified Sepiolite),简称IMS吸附剂.IMS对含锑废水的吸附性能依次为10%IMS＞5%IMS＞2.5%IMS＞海泡石精矿,其稳定性随温度的升高、FeCl3用量的增加而增强,盐对其稳定性的影响较小,强酸使IMS的结构严重破坏,负载铁大量脱落,对锑吸附能力下降.     

Modification of the ELPI to measure mean particle effective density in real-time

A new modification of electrical low pressure impactor (ELPI) for the particle effective density measurement is presented. The system is capable of real-time operation and it is based on the serial measurement of mobility and aerodynamic diameter. In the studied configuration, a zeroth order mobility analyser is installed inside of the ELPI-instrument. The system is feasible for single modal distributions. For several particle materials and varying size distributions, the measured average density values were within 15% of the values obtained with a reference method.     

家用液体洗涤剂的微生物防控

以DQC的管理形式,通过人、机、料、和环等多环节进行生产中的微生物控制。并制定了相关的微生物防控措施,参考和执行与日化相关的卫生标准。     

Oxidative Folding in the Mitochondrial Intermembrane Space in Human Health and Disease

Oxidative folding in the mitochondrial intermembrane space (IMS) is a key cellular event associated with the folding and import of a large and still undetermined number of proteins. This process is catalyzed by an oxidoreductase, Mia40 that is able to recognize substrates with apparently little or no homology. Following substrate oxidation, Mia40 is reduced and must be reoxidized by Erv1/Alr1 that consequently transfers the electrons to the mitochondrial respiratory chain. Although our understanding of the physiological relevance of this process is still limited, an increasing number of pathologies are being associated with the impairment of this pathway; especially because oxidative folding is fundamental for several of the proteins involved in defense against oxidative stress. Here we review these aspects and discuss recent findings suggesting that oxidative folding in the IMS is modulated by the redox state of the cell.     

60例急性有机磷中毒合并中间综合征的临床分析

目的探讨有机磷中毒合并中间综合征(IMS)患者预后的影响因素。方法回顾性分析60例有机磷中毒合并IMS患者的病例资料,包括一般情况、洗胃时间、气管切开与气管插管、血液灌流、机械通气时间,发生IMS的时间、心率、白细胞计数、胆碱酯酶活性等。根据生存情况分为生存组33例,死亡组27例。结果 2组的心率、白细胞计数、胆碱酯酶、发生IMS的时间比较差异均无统计学意义(P相似文献   

Production of neutral molecular clusters by controlled neutralization of mobility standards

Measuring aerosols and molecular clusters below the 3 nm size limit is essential to increase our understanding of new particle formation. Instruments for the detection of sub-3 nm aerosols and clusters exist and need to be carefully calibrated and characterized. So far calibrations and laboratory tests have been carried out using mainly electrically charged aerosols, as they are easier to handle experimentally. However, the charging state of the cluster is an important variable to take into account. Furthermore, instrument characterization performed with charged aerosols could be biased, preventing a correct interpretation of data when electrically neutral sub-3 nm aerosols are involved. This article presents the first steps to generate electrically neutral molecular clusters as standards for calibration. We show two methods: One based on the neutralization of well-known molecular clusters (mobility standards) by ions generated in a switchable aerosol neutralizer. The second is based on the controlled neutralization of mobility standards with mobility standards of opposite polarity in a recombination cell. We highlight the challenges of these two techniques and, where possible, point out solutions. In addition, we give an outlook on the next steps toward generating well-defined neutral molecular clusters with a known chemical composition and concentration.

Published with license by American Association for Aerosol Research