负载型纳米FeOZrO2/Al2O3催化剂的制备

主要研究制备以大孔A12O3,为基载体的负载型纳米FeOZrO2/Al2O3,复合载体.采用溶胶-凝胶法制备负载型纳米FeOZrO2/Al2O3,复合载体.利用比表面、透射电子显微镜(TEM)等对载体催化剂进行了表征.结果表明:负载型纳米FeOZrOJhl203复合载体的比表面积达到76.53 sq·m/g,FeOZrO2/Al2O3,中的FeO粒子约为40nm,较Fe0/Al2O3中FeO的粒子(100nm)小且分布均匀.     

Effect of a glow discharge on the formation of a surface layer on polycaproamide fibres in the presence of an organophosphorus compound

Conclusions The interaction of a glow discharge with polycaproamide fibres which have been impregnated with an involatile, unreactive liquid has been investigated.It has been shown that plasmochemical treatment of the impregnated fibres leads to immobilization of the impregnating agent.It has been established for the first time that on contact of a glow discharge plasma with an impregnated material, migration processes of the impregnating preparation take place both along the surface of the fibre and also in its volume. The intensity and ratio of these processes are determined by the discharge conditions.Translated from Khimicheskie Volokna, No. 2, pp. 38–40, March–April, 1990.     

4-Acetylantroquinonol B Suppresses Prostate Cancer Growth and Angiogenesis via a VEGF/PI3K/ERK/mTOR-Dependent Signaling Pathway in Subcutaneous Xenograft and In Vivo Angiogenesis Models

Prostate cancer is a major cause of cancer-related mortality in men in developed countries. The compound, 4-acetylantroquinonol B (4AAQB), is isolated from Antrodia cinnamomea (commonly known as Niu-Chang-Chih), which has been shown to inhibit cancer growth. However, the anticancer activity of 4AAQB has not previously been examined in prostate cancer. This study aimed to investigate the effect of 4AAQB on cancer and angiogenesis, as well as to explore its mechanism of action. Human prostate cancer cells (PC3) and human umbilical vein endothelial cells (HUVEC) were used in cell viability, cell migration, and cell cycle functional assays to evaluate the anticancer and antiangiogenic efficacy of 4AAQB in vitro. The effects of 4AAQB in vivo were determined using xenograft and angiogenesis models. The signaling events downstream of 4AAQB were also examined. The 4AAQB compound inhibited PC3 cell growth and migration, and reduced in vivo cancer growth, as shown in a subcutaneous xenograft model. Furthermore, 4AAQB inhibited HUVEC migration, tube formation, and aortic ring sprouting; it also reduced neovascularization in a Matrigel implant angiogenesis assay in vivo. The 4AAQB compound also decreased metastasis in the PC3 prostate cancer model in vivo. Serum or vascular endothelial growth factor (VEGF)-induced VEGF receptor 2 (VEGFR2), phosphoinositide 3-kinase (PI3K)/Ak strain transforming (Akt), and extracellular signal-regulated kinase ½ (ERK ½) phosphorylation were attenuated by 4AAQB in both PC3 and HUVEC. In conclusion, 4AAQB is a potential candidate for prostate cancer therapy.     

Examination of acetolysis products of phosphatidylcholine by gas chromatography-mass spectrometry

A comparison of monoacetyldiglycerides obtained from authentic phosphatidylcholines by acetolysis with those obtained by phospholipase C-acetylation was made to examine the intermolecular acyl migration, the intramolecular acyl migration between C-1 and C-2, and the formation of 1,3-isomer in the acetolysis reaction. Egg yolk phosphatidylcholine also was used. It was revealed that is acetolysis, the intermolecular acyl migration and selective degradation of polyunsaturated fatty acids did not take place at all. The intramolecular acyl migration, including the formation of 1,3-isomer, occurred to a small extent. Appreciable difference was not found in comparison of molecular species compositions of monoacetyldiglycerides derived by both methods from egg yolk phosphatidylcholine, except small differences found in the contents of two kinds of molecular species.     

Deposition of primary kainite from marine bitterns in solar evaporation

Mother liquor compositions during the solar evaporation of marine bitterns have been compared with corresponding isothermal equilibria in the NaCl-KCl-MgCl₂-MgSO₄-H₂O system. The compositions indicate that on solar evaporation of bitterns, potassium is deposited solely in the form of kainite, and that co-deposition of free sylvite and epsomite does not take place. It is also shown that during solar evaporation, the concentration of potassium is relatively low and that of magnesium relatively high, resulting in a more efficient precipitation of potassium in solar evaporation than in the forced or isothermal evaporation of sea water or of pure salts.     

High selective autocatalytic esterification of glutamic acid by benzyl alcohol with CuCl2 promoting

We found that the esterification of l-glutamic acid by benzyl alcohol is greatly promoted by CuCl₂ even in H₂O solvent, and the selectivity and yield of γ-benzyl ester of l-glutamic acid achieved 100% and 95.31%. Metal cation coordination to the amino acids via neighboring amino and carbonyl groups increased α position carboxyl acidity which initiates the esterification reaction to selectively take place on γ position carboxyl group. In this autocatalytic process H₂O has no effect on esterification.     

Phenomenological mass-balance-based model of migration tests in stationary conditions: Application to non-steady-state tests

In order to understand the phenomena that take place during a migration test, and to obtain a complete picture of the system through the pursuit of the transference numbers, a phenomenological mass-balance-based model of the evolution of all ionic species, has been developed. The model has been built on a series of steady-state migration tests and has been experimentally validated. Afterwards, it has been applied to migration tests in non-stationary conditions, and the resulting deductions have also been checked with experimental results. This has allowed the development of a new simplified way to determine the non-steady-state diffusion coefficients, D_ns, just from the registration of the current intensity circulating and the analysis of the surface concentration, C_s, after the test. In addition, the possibility of the tabulation of the different C_s for different external chloride concentrations and the application of different “binding factors” for each kind of binder is posed, which will allow the calculation of the D_ns from a simple migration test of the AASHTO type (ASTM C1202-91).     

仪化PTA装置试用国产醋酸钻、醋酸锰催化剂

仪化PTA装置用国产醋酸钻和醋酸锰催化剂代替进口产品进行工业试用,结果表明,国产催化剂可完全替代进口催化剂,且工艺运行稳定,产品质量优良。卜     

空气活性炭和臭氧活性炭工艺的比较研究

通过生产实践和模型同步研究的方式，对空气活性炭和臭氧活性炭在生产实践中的运行情况进行比较。在有预臭氧处理的前提下，讨论空气活性炭替代臭氧活性炭的可能性。当空气活性炭池进水氨氮含量低于一定标准时，空气活性炭可以在保证提高水质的前提下，达到降低运行成本的目的。     

Covercoat retardation of permeation through sheet molding compound

Permeation of gases through polymers may be retarded by applying to the polymers a coating of a less permeable material. We have devised techniques to quantitatively measure rates of water vapor permeation at typical atmospheric pressures and compositions through polymer and coating films, and we apply these techniques here to a crosslinked polyester resin with glass fiber reinforcement, coated with a crosslinked thio-ene formulation. The coating is shown to inhibit water vapor permeation by about a factor of thirty over the uncoated value. H₂S permeation constants are also derived; they are some three orders of magnitude smaller than those of H₂O but show similar coated/uncoated permeation effects. The controlling factor in the retardation is suggested by experimental evidence to be a graft copolymer formed at the covercoat–sheet molding compound interface by the ultraviolet curing process.     

Effect of (s)-(+)-ethyl-2-phenylbutanoate and poly(ethylene terephthalate) on the polymerization of propylene and 3-methyl-1-pentene over TiCl3-AlET3

Summary (s)-(+)-Ethyl-2-phenylbutanoate was synthesized and polymerizations of propylene and racemic 3-methyl-1-pentene were conducted over TiCl₃-AlEt₃ combined with the compound. The addition of the compound caused a significant increase in the isotacticity of polypropylene as well as a substantial decrease in the activity. However, stereoelective polymerization of racemic 3-methyl-1-pentene didn't take place at all. Propylene polymerization was also carried out over TiCl₃-AlEt₃ by using poly(ethylene terephthalate) in place of the compound. The results obtained have led to the conclusion that these additives act mainly as reagents to reduce the concentration of AlEt₃ by the formation of the complexes between AlEt₃ and these additives.     

Infrared spectroscopic study of the mechanism of interaction in polymer blends

IR spectroscopy showed that dipole-dipole interactions of the hydrogen bond type with formation of stereocomplexes take place between macromolecules of the copolymer of ethylene with vinyl acetate (CEVA) and copolyamide (CPA) during fabrication of blends. CEVA affects the network of intermolecular hydrogen bonds in CPA like a polar solvent: due to the reaction of the carbonyl (C=O) group in CEVA with the amide groups in CPA, rearrangement of the network of hydrogen bonds in the polyamide and formation of a new stereocomplex take place. State Academy of Light Industry of Ukraine, Kiev. Translated fromKhimicheskie Volokna, No. 3, pp. 23–25, May–June, 1999.     

高含氮高浓度有机废水生物处理技术研究

分析了石家庄化纤公司己内酰胺生产废水的水质状况,指出该废水属高含氮、高浓度有机废水,虽然可生物降解性能较好,但因处理水在好氧硝化池(O1)中水力停留时间不够,难以达到硝化阶段,导致了原有生物处理工艺A／O／A／O系统无法正常运行。根据生物脱氮原理,提出了以SBR法作为处理工艺主体的ENSBR／BDAR／PCOR三段生物处理工艺。实验数据和生产运用表明,高含氮高浓度有机废水经该工艺处理后出水水质达到国家二级排放标准要求。     

Theoretical investigation of catalytic HCO3 hydrogenation in aqueous solutions

Density functional theory along with a dielectric continuum solvation model has been applied to identify possible reaction intermediates for the catalytic hydrogenation of HCO₃⁻ anion into HCO₂⁻ that occurs in aqueous solutions in the presence of water-soluble ruthenium complexes. Bicarbonate ion is shown to coordinate to a Ru-dihydride species, which then undergoes a protonation process that yields a CO₂ complex. The CH bond formation is found to take place via CO₂ insertion into a RuH bond and the direct elimination of the formate product is shown to be an energetically favored step, which is assisted by the water medium. We find that water is directly involved in the reaction as a protonating/deprotonating agent and also acts as a coordinating ligand.     

Evaporation of single droplets of ethanol-fuel oil mixtures

Measurements of droplet evaporation behaviour are reported for mixtures of pure and denatured ethanol with No. 2 fuel oil. A model for the evaporation of droplets of these mixtures is presented which uses continuous thermodynamics to describe the fuel oil fraction. Activity coefficients were used to describe non-ideal phase equilibrium behaviour. Distribution function parameters for the fuel oil were fitted from a continuous thermodynamics simulation of the ASTM distillation test; this simulation was also used to test the accuracy of the phase equilibrium model. The model is shown to give very good agreement with the measurements. Internal boiling of the liquid is seen to take place during evaporation of the alcohol, but is not sufficiently violent to eject mass from the droplet.     

复合氧化剂在合成导电聚苯胺中的应用

以苯胺为单体,采用(NH4)2S2O8和抗坏血酸组成的复合氧化剂,在硫酸水溶液中,用化学氧化法直接合成导电聚苯胺。系统地研究了复合氧化剂配比、硫酸的浓度、氧化剂浓度等因素对苯胺聚合反应的影响。结果表明,该方法聚合反应的最佳条件为:在10~25℃的温度范围内,不加氮气保护条件下,苯胺1.0 mol/L,H2SO41 mol/L,(NH4)2S2O81 mol/L,(NH4)2S2O8/抗坏血酸(C6H8O6)的配比为10∶1,合成了电导率达1.33 S/cm、产率达82.17%的聚苯胺。通过红外光谱和X衍射研究了通过不同氧化剂聚合得到聚苯胺的结构变化,结果表明,复合氧化剂氧化聚合得到的聚苯胺结晶比通过过硫酸胺作氧化剂聚合得到的聚苯胺结晶好,并且相应基团在红外光谱上发生红移。     

Evaluation of the sorption of metal ions on a complexing resin from different solutions based on the Gibbs–Donnan model

The intrinsic protonation and complexation constants of an ion-exchange complexing resin, previously determined in condition of trace metal ions on the basis of the Gibbs–Donnan model of ion-exchange resins, were here used to evaluate the concentration of metal ions sorbed on the resin when the metal ion is in excess. The resin considered was a commercial one, containing carboxylic groups at a concentration of 10 mmol g⁻¹ of dry resin. Metal ions complexable by the active groups present in the resin phase, i.e. alkaline earth metals and cadmium(II), were investigated, together with a not complexable metal ion, sodium, which enters in the resin phase only by diffusion and ion-exchange. The calculation method is an iterative one, taking into account the diffusion and ion-exchange in the case of the not complexable metals, and the complexation in the case of the complexable metal ions. The concentration of metals in the resin phase calculated by the proposed procedure was compared with that obtained experimentally in some representative solutions at different composition and acidity. The agreement was acceptable, showing that the intrinsic complexation constants are of help not only in conditions of trace metal, but also for evaluations at completely different conditions. In the case of complexable metal ions it was shown that the complexation in the resin phase is the most important sorption mechanism, even if ion-exchange takes place at high acidity, when the complexation is negligible.     

纳米Al2O3透明耐磨复合涂料的研制

选用纳米Al2O3作为填料，用硬脂酸进行亲油处理，与羟基丙烯酸树脂或聚酯复合，制备了纳米透明耐磨涂料。红外光谱分析表明：硬脂酸与纳米Al2O3表面的羟基进行了反应。用分光光度计、磨耗仪及摆杆硬度计测定了涂料的透明性和耐磨性，添加15％(质量分数)的纳米Al2O3，涂膜的耐磨性能提高了100％，相对于有机玻璃底材耐磨性能提高了2．75倍，可见光平均透过率大于80％。     

锡槽中的化学反应及其对浮法玻璃质量的影响

在锡槽内,玻璃液、锡液和保护气体构成一个多相体系,各相界面都进行着复杂的氧化、还原反应.在浮法工艺条件下,钠钙硅玻璃熔体和纯锡液接触时,会产生多相反应.溶解在锡液中的钠和氧在锡液/耐火材料界面处析出Na2O,进而与槽底砖反应而使槽底砖破坏.氧化锡、氧化亚锡、硫化亚锡等锡的化合物是对玻璃质量产生影响的几种主要化合物.浮法玻璃所特有的几种缺陷-"钢化彩虹"、"沾锡"、"斑点"和"小波纹"都是锡及锡化合物参与反应的结果.     

Assembly of Fully Substituted 2H-Indazoles Catalyzed by Cu2O Rhombic Dodecahedra and Evaluation of Anticancer Activity

Simultaneous C−N, and N−N bond-forming methods for one-pot transformations are highly challenging in synthetic organic chemistry. In this study, the Cu₂O rhombic dodecahedra-catalyzed synthesis of 2H-indazoles is demonstrated with good to excellent yields from readily available chemicals. This one-pot procedure involves Cu₂O nanoparticle-catalyzed consecutive C−N, and N−N bond formation followed by cyclization to yield 2H-indazoles with broad substrate scope and high functional group tolerance. Various cell-based bioassay studies demonstrated that 2H-indazoles inhibit the growth of cancer cells, typically through induction of apoptosis in a dose-dependent manner. Moreover, 2H-indazoles tested in the MDA-MB-468 cell line were capable of inhibiting cancer cell migration and invasion. Thus, it is shown that 2H-indazoles have potent in vitro anticancer activity that warrant further investigation of this compound class.