Organic memory capacitor device fabricated with Ag nanoparticles

In this study, it is demonstrated that an organic memory structure using pentacene and citrate-stabilized silver nanoparticles (Ag NPs) as charge storage elements on dielectric SiO2 layer and silicon substrate. The Ag NPs were synthesized by thermal reduction method of silver trifluoroacetate with oleic acid. The synthesized Ag NPs were analyzed with high resolution transmission electron microscopy (HRTEM) and selected area electron diffraction (SAED) for their crystalline structure. The capacitance versus voltage (C-V) curves obtained for the Ag NPs embedded capacitor exhibited flat-band voltage shifts, which demonstrated the presence of charge storages. The citrate-capping of the Ag NPs was confirmed by ultraviolet-visible (UV-VIS) and Fourier transformed infrared (FTIR) spectroscopy. With voltage sweeping of +/-7 V, a hysteresis loop having flatband voltage shift of 7.1 V was obtained. The hysteresis loop showed a counter-clockwise direction. In addition, electrical performance test for charge storage showed more than 10,000 second charge retention time. The device with Ag NPs can be applied to an organic memory device for flexible electronics.     

Improved metal cluster deposition on a genetically engineered tobacco mosaic virus template

Improved depositions of various metal clusters onto a biomolecular template were achieved using a genetically engineered tobacco mosaic virus (TMV). Wild-type TMV was genetically altered to display multiple solid metal binding sites through the insertion of two cysteine residues within the amino-terminus of the virus coat protein. Gold, silver, and palladium clusters synthesized through in situ chemical reductions could be readily deposited onto the genetically modified template via the exposed cysteine-derived thiol groups. Metal cluster coatings on the cysteine-modified template were more densely deposited and stable than similar coatings on the unmodified wild-type template. Combined, these results confirm that the introduction of cysteine residues onto the outer surface of the TMV coat protein enhances the usefulness of this virus as a biotemplate for the deposition of metal clusters.     

基于单片机的数码监控装置

本文主要介绍了基于CMOS图像传感器(OV7620)、单片机AT89C51、闪速存储器和以及U盘控制芯片SL811HS的简易数码监控设备.介绍了CMOS图像传感器、USB接口芯片PDIUSBD12的基本原理和使用方法.整个系统由单片机控制,监控的结果以图像数据的形式存储于闪速存储器中,也可以通过USB接口传送到计算机中,实现了800×600图像的实时传输和显示.     

A transparent and flexible organic bistable memory device using parylene with embedded gold nanoparticles

In this work, we demonstrate the fabrication of a transparent and flexible memory device in the simple structure of metal/dielectric/metal (MIM). Here, the MIM structure consists of gold electrode/200 nm Parylene-C/20 nm gold nanoparticles/100 nm Parylene-C/indium-tin-oxide (ITO) coated polyethylene terephthalate (PET). The use of parylene as the dielectric layer is important to ensure that there is no thermal stress induced on the flexible ITO/PET substrate compare to other reported works using various organic dielectrics that require high temperature curing. In addition, parylene deposition does not disturb the drop-casted gold nanoparticles. Hence, the use of parylene will be the right step forward in the fabrication of mechanically flexible and optically transparent devices. Current versus voltage (I–V) plot shows the presence of hysteresis suggesting the charge storage capability as a memory device. In the I–V plot, three distinct regions based on the slope have been identified and the transport mechanisms are discussed and explained. The fabricated device shows similar behavior as write-once-read-many memory device and can be programmed with either positive or negative bias voltage. However, the memory device shows unstable current state when being bent under different curvature diameters.     

Atomic layer deposition on biological macromolecules: metal oxide coating of tobacco mosaic virus and ferritin

Decoration of nanoparticles, in particular biomolecules, gathered high attention in recent years.(1-7) Of special interest is the potential use of biomolecules as templates for the fabrication of semiconducting or metallic nanostructures.(1-7,26) In this work we show the application of atomic layer deposition, a gas-phase thin film deposition process, to biological macromolecules, which are frequently used as templates in nanoscale science, and the possibility to fabricate metal oxide nanotubes and thin films with embedded biomolecules.(1-13).     

Nanostructured medical device coatings based on self-assembled poly(lactic-co-glycolic acid) nanoparticles

Here we present a new method for providing nanostructured drug-loaded polymer films which enable control of film surface morphology and delivery of therapeutic agents. Silicon wafers were employed as models for implanted biomaterials and poly(lactic-co-glycolic acid) (PLGA) nanoparticles were assembled onto the silicon surface by electrostatic interaction. Monolayers of the PLGA particles were deposited onto the silicon surface upon incubation in an aqueous particle suspension. Particle density and surface coverage of the silicon wafers were varied by altering particle concentration, incubation time in nanoparticle suspension and ionic strength of the suspension. Dye loaded nanoparticles were prepared and assembled to silicon surface to form nanoparticle films. Fluorescence intensity measurements showed diffusion-controlled release of the dye over two weeks and atomic force microscopy (AFM) analysis revealed that these particles remained attached to the surface during the incubation time. This work suggests that coating implants with PLGA nanoparticles is a versatile technique which allows drug release from the implant surface and modulation of surface morphology.     

基于图像拼接方法的计量过程数字化记录

针对单幅CCD相机所获指针式表盘图像存在的视角误差问题,提出了基于SIFT(尺度不变特征变换)的图像拼接方法,将分别准确获取的标准器与被检器示值图像进行无缝拼接,并通过实验验证了方法的有效性和可行性。     

基于形状记忆合金的新型消能减震装置抗震性能研究

本文首先通过形状记忆合金的材性试验研究了形状记忆合金的超弹性变形性能,并将其等效拟合为多线性模型,得到其设计参数,并详细介绍了分析计算时所采用的形状记忆合金的本构模型。然后,针对框架结构的变形特点,提出了一种基于形状记忆合金的消能减震装置,即在底层框架柱的反弯点附近设置锚固装置,形状记忆合金索的上端固定在锚固装置上,将其下端锚固在地下,在震时通过其来回反复变形耗散地震能量。然后通过有限元程序对设置形状记忆合金索的新型框架与普通框架进行静力推覆分析和低周反复分析,研究表明新型框架不仅屈服承载力和极限承载力高于普通框架,而且其滞回环更加饱满,累积塑性滞回耗能能力提高了41.4%,形状记忆合金索的滞回环也很饱满,具有优良的耗能能力,最后,还比较了对角设置形状记忆合金索的框架的耗能能力与本消能减震装置的耗能能力。因此该消能减震装置在减轻框架柱震害方面具有一定的工程应用价值和前景。     

Au nanocrystals grown on a better-defined one-dimensional tobacco mosaic virus coated protein template genetically modified by a hexahistidine tag

In this paper, tobacco mosaic virus (TMV) coated protein (CP) was genetically modified by introducing a hexahistidine tag into it for a well-defined one-dimensional template, on which Au nanocrystals (NCs) were grown. The results showed that genetic modification could not only ameliorate the one-dimensional structure of the template, but also improve the growth density of Au NCs on the template. This indicated that genetic modification could be an effective method to modulate the structure of the TMVCP template-based nanocomposites allowing for a broader application of them.     

Tip-enhanced Raman detection of antibody conjugated nanoparticles on cellular membranes

Tip enhanced Raman scattering (TERS) microscopy is used to image antibody conjugated nanoparticles on intact cellular membranes. The combination of plasmonic coupling and the resultant electric field obtained from intermediate focusing of a radially polarized source gives rise to Raman images with spatial resolution below 50 nm. Finite element method calculations are used to explain the origins of the observed image resolution and spectroscopic signals. The observed Raman scattering provides information about the biomolecules present near the nanoparticle probes. The results show that aggregates of nanoparticles produce spectroscopic results similar to those reported from other surface enhanced Raman spectroscopies, e.g., shell isolated nanoparticle enhanced Raman spectroscopy (SHINERS) and aggregated nanoparticles; however, TERS enables the detection of isolated nanoparticles on cell membranes where the observed spectra provide information about the interaction of the specific biomolecule conjugated to the nanoparticle probe. These measurements present a new technique for exploring biomolecular interactions on the surface of cells and tissue.     

Switching memory cells constructed on plastic substrates with silver selenide nanoparticles

Programmable metallization cell (PMC) memory is a kind of next generation non-volatile memory that has attracted increasing attention in recent years as a possible replacement for flash memory. In spite of the considerable amount of research focused on the fabrication of non-volatile memories on plastic substrates with lightweight, thin, and bendable characteristics, there have been few studies on the fabrication of PCM memory on flexible substrates. In this study, we synthesized Ag₂Se nanoparticles (NPs) by a positive-microemulsion method and constructed PMC memories on plastic substrates with programmable layers formed by the spin-coating of the Ag₂Se NPs. To the best of the knowledge, this is the first attempt to construct PMC memory on plastic substrates by the spin-coating of Ag₂Se NPs. The Ag₂Se NPs synthesized in this study had a uniform size of 2 nm and interestingly showed α-phase (high temperature phase) stability at room temperature. Switching behaviors were observed through the voltage scanning on the fabricated memories with applicable switching voltages. However, the resistance ratios of the off-state to the on-state were quite small. The possible reasons for the α-phase stability of the Ag₂Se NPs at room temperature and the detailed memory characteristics will be described in this article.     

Enhancement of photoconduction in a conjugated polymer through doping with copper nanoparticles

We investigated the effect of doping with copper nanoparticles (Cu NPs) on photoconductivity of poly(3-hexylthiophene) P3HT films. ∼20 nm Cu NPs were fabricated in a simple one step reduction process in hydrophobic environment. Structure, morphology and optical properties of the Cu nanoclusters were characterized. Films of P3HT containing Cu NPs were fabricated and their optical and electrical properties investigated. The results indicate that the change of the efficiency of the light absorption brought about by the effect of plasmonic resonances is minor, but there is a substantial influence of the metal nanoparticles on the efficiency of the photogeneration of charges in P3HT.     

Ketoconazole‐conjugated ZnO nanoparticles based semi‐solid formulation and study their impacts on skin disease

In this study, the ketoconazole‐conjugated zinc oxide (ZnO) nanoparticles were prepared in a single‐step approach using dextrose as an intermediate compound. The physical parameters confirmed the drug conjugation with ZnO and their size was around 70–75 nm. The drug loading and in vivo drug release studies indicated that the –CHO group from the dextrose increase the drug loading up to 65% and their release kinetics were also studied. The anti‐fungal studies indicated that the prepared nanoparticles exhibit strong anti‐fungal activity and the minimum concentration needed is 10 mg/ml. The nanoparticles loaded semi‐solid gel was prepared using carbopol, methylparaben, propyl paraben and propylene glycol. The in vitro penetration of the ketoconazole‐conjugated nanoparticles was studied using the skin. The results indicated that the semi‐solid gel preparations influenced the penetration and also favoured the accumulation into the skin membrane. The veterinary clinical studies indicated that the prepared gel is highly suitable for treatment of Malassezia.Inspec keywords: II‐VI semiconductors, skin, biomedical materials, antibacterial activity, wide band gap semiconductors, drug delivery systems, nanomedicine, drugs, diseases, gels, nanofabrication, nanoparticles, zinc compounds, biomembranes, veterinary medicineOther keywords: strong anti‐fungal activity, propyl paraben, propylene glycol, semisolid gel preparations, skin membrane, veterinary clinical studies, semisolid formulation, skin disease, ketoconazole‐conjugated zinc oxide nanoparticles, single‐step approach, physical parameters, drug conjugation, drug loading, release kinetics, dextrose, in vivo drug release studies, carbopol, methylparaben, in vitro penetration, Malassezia, ZnO     

Deposition of platinum clusters on surface-modified Tobacco mosaic virus

Nanoscaled Pt conductors were prepared from genetically engineered Tobacco mosaic virus (TMV) templates through Pt cluster deposition on the outer surface of the TMV. Pt clusters were synthesized and deposited on the engineered TMV with surface-exposed cysteine via the in situ mineralization of hexachloroplatinate anions. This deposition was driven by the specific binding between thiols and the solid metal clusters. In addition, Pt-thiolate adducts are suggested to form on the engineered TMV in aqueous solutions that work as nucleation sites for the formation of the Pt clusters. The specific binding between Pt clusters and the engineered TMV template was investigated using UV/vis spectrophotometry and quartz crystal microbalance (QCM) analysis. The electric conductance of Pt-deposited TMV was greater than that of the uncoated TMV virion particles. This result suggests the application of metal cluster-deposited engineered TMV in future electrical devices such as rapid response sensors.     

Resistive random access memory utilizing ferritin protein with Pt nanoparticles

This study reports controlled single conductive paths found in resistive random access memory (ReRAM) formed by embedding Pt nanoparticles (Pt NPs) in NiO film. Homogeneous Pt NPs produced and placed by ferritin protein produce electric field convergence which leads to controlled conductive path formation. The ReRAM with Pt NPs shows stable switching behavior. A Pt NP density decrease results in an increase of OFF state resistance and decrease of forming voltage, whereas ON resistance was independent of the Pt NP density, which indicates that a single metal NP in a memory cell will achieve low power and stable operation.