共查询到20条相似文献,搜索用时 78 毫秒
1.
B Agianian K Leonard E Bonte H Van der Zandt PB Becker PA Tucker 《Canadian Metallurgical Quarterly》1999,285(2):527-544
The Drosophila GAGA factor binds specifically to the sequence GAGAG, and synergises with nucleosome remodelling factor to remodel chromatin in vitro. It consists of an N-terminal domain (POZ/BTB) which mediates protein-protein interactions, a central region which contains the DNA-binding domain, and a C-terminal glutamine-rich region. It is shown that the glutamine-rich region is responsible for the formation of fibres in vitro which, on the basis of their tinctorial properties and CD spectra, may be classified as amyloid fibres. A large structural change, probably resulting in beta-sheet structure, is observed upon fibre formation. Mutants containing the central region, either alone or together with the glutamine-rich region, are largely lacking in secondary structure but they bind specifically to the cognate DNA and are able to remodel chromatin in vitro. Consequently, neither the N-terminal domain nor the C-terminal glutamine-rich regions of the GAGA factor are necessary for chromatin remodelling in vitro. 相似文献
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
E Ito T Toki H Ishihara H Ohtani L Gu M Yokoyama JD Engel M Yamamoto 《Canadian Metallurgical Quarterly》1993,362(6419):466-468
14.
AD Agulnick M Taira JJ Breen T Tanaka IB Dawid H Westphal 《Canadian Metallurgical Quarterly》1996,384(6606):270-272
15.
16.
17.
18.
The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA 总被引:1,自引:0,他引:1
AH Batchelor DE Piper FC de la Brousse SL McKnight C Wolberger 《Canadian Metallurgical Quarterly》1998,279(5353):1037-1041
19.