Sick Building Syndrome and Psychosocial Factors - a Literature Review

Abstract Sick building syndrome (SBS) with an unknown etiology has led researchers to focus on the role of psychosocial factors in the work environment as well as on individual characteristics in SBS. Recent research has suggested that psychosocial factors are quite strongly associated with SBS. The associations have been confirmed in buildings that were beforehand considered to be problem cases, and also in buildings whose condition was not known in advance. However, SBS symptoms could not be attributed to psychosocial factors alone. Most of the previous studies have supported the conclusion that SBS most likely is of multifactorial origin related to chemical, physical, biological and psychosocial factors that interact or coincide with one another. Unfortunately, for the time being, it is not possible to characterize adequately the relationship between the various risk factors and the possible mechanisms of SBS. There is an urgent need for more empirical research, especially follow-up studies and interventions, for development of the methodology and for new theory-building in order to better understand the relations between environmental factors, personal factors and the symptoms of SBS. In this literature review, SBS is viewed from an occupational stress perspective.     

Sick Building Syndrome in an Office Building Formerly Used by a Pharmaceutical Company: A Case Study

Abstract In the past two decades, a group of health problems related to the indoor environment – generally termed sick building syndrome (SBS) – has emerged. We present an investigation of SBS in employees of a ministry working in a naturally ventilated office building that formerly had been used by a pharmaceutical company. A preceding environmental monitoring had failed to identify the cause(s) for the complaints. We conducted a questionnaire-based investigation and categorized the building sections and rooms according to their renovation status and their former use, respectively. The highest level of complaints was found among the employees working in rooms that in the past had been used for the production or storage of various pharmaceutical products suggesting that pharmaceutical odors may be a risk factor for SBS. Clinical laboratory tests did not show any unusual results. We conclude that the former use of a building for production and storage of pharmaceutical products should be considered as a possible risk factor for complaints about indoor air quality, e.g., when advising about or planning for renovations of buildings formerly used for production, handling, or storing of chemicals.     

Individual and Occupational Correlates of the Sick Building Syndrome

Results of a questionnaire survey of 939 workers from 5 air-conditioned offices where smoking was prohibited are reported. Levels of carbon monoxide, carbon dioxide, formaldehde, respirable particulates, and temperature, relative humidity, and illuminance were measured in these buildings, but these did not correlate with symptom reports. The number of sick building syndrome symptoms per worker was related linearly to perceived indoor air quality, job stress, job satisfaction, allergies, eyewear, and seasonal affective disorder. Two hundred and fifty five of these workers also completed a battery of psychological measures. Measures of depression, personality variables, situational stress, vulnerability to stress, and individual differences in circadian rhythms did not correlate with the numbers of sick building syndrome symptoms per worker, although depression did correlate with the number of symptoms when these were weighted for their frequency of occurrence in the previous month. Job stress and perceptions of indoor air quality correlated with both the unweighted and weighted indices of sick building syndrome.     

Building‐related health symptoms and classroom indoor air quality: a survey of school teachers in New York State

Most previous research on indoor environments and health has studied school children or occupants in non‐school settings. This investigation assessed building‐related health symptoms and classroom characteristics via telephone survey of New York State school teachers. Participants were asked about 14 building‐related symptoms and 23 classroom characteristics potentially related to poor indoor air quality (IAQ). Poisson regression analysis was used to assess the relationship between these symptoms and each classroom characteristic, controlling for potential confounders. About 500 teachers completed the survey. The most frequently reported classroom characteristics included open shelving (70.7%), food eaten in class (65.5%), dust (59.1%), and carpeting (46.9%). The most commonly reported symptoms included sinus problems (16.8%), headache (15.0%), allergies/congestion (14.8%), and throat irritation (14.6%). Experiencing one or more symptoms was associated most strongly with reported dust (relative risk (RR) = 3.67; 95% confidence interval (CI): 2.62–5.13), dust reservoirs (RR = 2.13; 95% CI: 1.72–2.65), paint odors (RR = 1.73; 95% CI: 1.40–2.13), mold (RR = 1.71; 95% CI: 1.39–2.11), and moldy odors (RR = 1.65 95% CI: 1.30–2.10). Stronger associations were found with increasing numbers of reported IAQ‐related classroom characteristics. Similar results were found with having any building‐related allergic/respiratory symptom. This research adds to the body of evidence underscoring the importance to occupant health of school IAQ.     

Perceived Air Quality,Sick Building Syndrome (SBS) Symptoms and Productivity in an Office with Two Different Pollution Loads

Abstract Perceived air quality, Sick Building Syndrome (SBS) symptoms and productivity were studied in an existing office in which the air pollution level could be modified by introducing or removing a pollution source. This reversible intervention allowed the space to be classified as either non-low-polluting or low-polluting, as specified in the new European design criteria for the indoor environment CEN CR 1752 (1998). The pollution source was a 20-year-old used carpet which was introduced on a rack behind a screen so that it was invisible to the occupants. Five groups of six female subjects each were exposed to the conditions in the office twice, once with the pollution source present and once with the pollution source absent, each exposure being 265 min in the afternoon, one group at a time. They assessed the perceived air quality and SBS symptoms while performing simulated office work. The subject-rated acceptability of the perceived air quality in the office corresponded to 22% dissatisfied when the pollution source was present, and to 15% dissatisfied when the pollution source was absent. In the former condition there was a significantly increased prevalence of headaches (P= 0.04) and significantly lower levels of reported effort (P=0.02) during the text typing and calculation tasks, both of which required a sustained level of concentration. In the text typing task, subjects worked significantly more slowly when the pollution source was present in the office (P=0.003), typing 6.5% less text than when the pollution source was absent from the office. Reducing the pollution load on indoor air proved to be an effective means of improving the comfort, health and productivity of building occupants.     

Outdoor Air Contaminants and Indoor Air Quality under Transient Conditions

The indoor concentrations of contaminants originating from outdoor sources have been measured and calculated under transient conditions. The results show that contaminants that are supplied to an office building via the ventilation system can reach considerably high concentration levels. The indoor/outdoor concentration ratio and time lag are dependent on the air change rate. In buildings with low air change rates the indoor concentration variations are smoothed out compared to buildings with high air change rates. The results from the theoretical model are compared to the results from both laboratory and field measurements and the model is verified for well mixed conditions in a 20 m³ test chamber. The model can be used to simulate different control strategies for reduction of indoor contaminant concentrations related to outdoor sources. One such control strategy is based on reduction of the outdoor air change rate during periods with peak outdoor contaminant concentrations.     

Case Study of Factors contributing to a Crisis Building

Abstract Employees of a communications firm experienced an acute outbreak of nonspecific illness related to the workplace. Symptoms consisted primarily of coughing, throat irritation, shortness of breath and disorientation. Fifty-one individuals sought emergency medical care, and the building was evacuated. A multidisciplinary team was assembled to investigate and resolve the problem. Investigation activities focused on three major areas: epidemiology; environmental measurement; and mechanical engineering. Results indicated that the outbreak was due to multiple factors working in concert. The inside of the air handling system was contaminated with microbial growth and particulate matter; chemical products were used throughout the building with little control over use patterns; and the HVAC system was not delivering acceptable quantities of outdoor air to the employees’ breathing zones. Two unusual events may have triggered the employees’ response. An unusual odor/taste was reported, and the outside air damper abruptly opened and closed, possibly dislodging particulate matter from inside the air handling system. It appeared that psychosocial factors played an important role. Prevention of similar crises could be achieved by implementation of a policy/procedure that addresses specific responsibilities, communications, preventive maintenance, acceptable outdoor air ventilation rates, and guidelines for reporting and investigation.     

Persistent allergic rhinitis and indoor air quality perception--an experimental approach

In order to compare patterns of indoor air perception, including perceptions of temperature, air movement, indoor air quality (IAQ), mental concentration, and comfort, 33 subjects either with persistent allergic rhinitis or controls were exposed to different temperatures and constant relative humidity in an experimental office environment. Results were obtained by means of a self-administered visual analogue scale, analyzed using mean score comparisons and principal component analysis. At 14 degrees C, the rhinitis group reported higher scores for sensations of air dryness than controls. At 18 degrees C, in the rhinitis group, there was a correlation between dry, stagnant air, and difficult mental concentration. This group also correlated heat, dry air, and poor IAQ, in contrast to the control group, which correlated comfort, easy mental concentration, and freshness. At 22 degrees C, the rhinitis group correlated heat, dryness, stagnant air, and overall discomfort. This group also correlated non-dry air, freshness, and comfort, whereas the control group correlated heat, humidity, good indoor air, freshness, and comfort. This study suggests that the rhinitis group perceives indoor temperatures of 14 degrees C as dryer than controls do, and that at 18 and 22 degrees C this group positively correlates different adverse perceptions of IAQ. By means of a self-administered questionnaire in an experimental condition, the present study compares subjective patterns of indoor air perception from individuals with respiratory allergy (allergic rhinitis) to control individuals. It reports different patterns of perception of indoor air quality (IAQ) between the two groups, suggesting that allergic individuals could have different IAQ perception.     

Development of New Volatile Organic Compound (VOC) Exposure Metrics and their Relationship to “Sick Building Syndrome” Symptoms

Abstract Occupants of office buildings are exposed to low concentrations of complex mixtures of volatile organic compounds (VOCs) that encompass a number of chemical classes and a broad range of irritancies. “Sick building syndrome” (SBS) is suspected to be related to these exposures. Using data from 22 office areas in 12 California buildings, seven VOC exposure metrics were developed and their ability to predict self-reported SBS irritant symptoms of office workers was tested. The VOC metrics were each evaluated in a multivariate logistic regression analysis model adjusted for other risk factors or confounders. Total VOCs and most of the other metrics were not statistically significant predictors of symptoms in crude or adjusted analyses. Two metrics were developed using principal components (PC) analysis on subsets of the 39 VOCs. The Irritancy/PC metric was the most statistically significant predictor of adjusted irritant symptoms. The irritant potencies of individual compounds, highly correlated nature of indoor VOC mixtures, and probable presence of potent, but unmeasured, VOCs were variously factored into this metric. These results, which for the first time show a link between low level VOC exposures from specific types of indoor sources to SBS symptoms, require confirmation using data sets from other buildings.     

Air quality in rooms conditioned by chilled ceiling and mixed displacement ventilation for energy saving

A transient-contaminant-transport model is developed for assessing IAQ in the breathing zone when introducing return air into rooms conditioned by CC/DV system to save energy. The steady state transport model of [1] is extended to transient conditions while accounting for significant wall plumes associated with external loads.Experiments are performed to validate the extended model predictions of IAQ expressed in the level of CO₂ concentration. Experiments are conducted in a chamber with two external walls in Kuwait Climate. Measurements are recorded in time of the air temperature and CO₂ concentration at selected locations in the room and compared with values predicted by the model. Experimental results agreed well with model predictions. The maximum errors in predicted CO₂ concentrations are less than ±25 ppm in presence of external load. 60% fresh air fraction resulted in 37% less energy consumption compared with 100% fresh air CC/DV system.The validated model is applied to a case study in Kuwait to evaluate energy saving over the cooling season for a typical office space while using mixed DV air. Energy savings of up to 20.6% can be realized using mixed supply air while maintaining IAQ compared with energy used for the 100% fresh air.     

Sick Building Syndrome (SBS) in Office Workers and Facial Skin Symptoms among VDT-Workers in Relation to Building and Room Characteristics: Two Case-Referent Studies

In two case-referent studies the associations between questionnaire symptom reports, expressed as SBS (Sick Building Syndrome) in office workers or facial skin symptoms among VDT-workers, and physical data from offices in 160 buildings were investigated. The results show that low outdoor airflow rate and presence of certain pollution sources, such as copying machines, tended to be associated with an elevated prevalence of SBS. Buildings built or remodeled between 1977 and 1986, low-rise buildings with a horizontal roof and a foundation of the type “concrete slab on the ground”, as well as rooms with flourescent tube lighting with metal shields were also associated with higher SBS risks. A number of factors were associated with an overrepresentation of skin symptoms among VDT-workers such as type of foundation (concrete slab on the ground and crawlspace), the frequency of floor cleaning and type of lighting (fluorescent tubes with glass/plastic shields). It has not been possible to establish conclusive explanations for these associations. The difference in associations between building factors and S B S, and between building factors and skin symptoms among VD Tworkers points to different etiologies.     

Evaluation of Fungal Growth on Fiberglass Duct Materials for Various Moisture,Soil, Use,and Temperature Conditions

Abstract Fiberglass duct materials are commonly used in both residential and commercial heating, ventilation, and air-conditioning (HVAC) systems to provide the needed thermal insulation and noise control. Many building investigations have documented biocontamination of these materials, and the appropriateness of their use in high humidity locations has come into question. A series of experiments, each lasting 6 weeks, was conducted in static environmental chambers to assess some of the conditions that may impact the ability of a variety of fiberglass materials to support the growth of a fungus, Penicillium chrysogenum. Three different fiberglass duct liners (FDL), one fiberglass duct board, and fiberglass insulation, all newly purchased, were obtained as were samples of used (>5 years old) materials. Samples of these materials were tested to evaluate the effects of moisture, soil, use, and temperature on their ability to support the growth of P. chrysogenum. These studies demonstrated that P. chrysogenum could amplify under conditions of low (12°C) and room (23°C) temperature and high relative humidity on samples of one of the newly purchased materials, and that either wetting and/or soiling increased the materials’ susceptibility. P. chrysogenum was able to grow on all the used material samples. While the results of this study apply directly only to fiberglass duct materials, they suggest that dust accumulation and/or high humidity should be properly controlled in any HVAC duct to prevent the growth of P. chrysogenum.     

Volatile organic compound emissions from latex paint--Part 1. Chamber experiments and source model development

Latex paints are widely used in residential and commercial indoor environments. The surface areas covered by the paints in these environments are relatively large. Thus, latex paints have the potential for having a major impact on indoor air quality (IAQ). A study was undertaken to develop methods for evaluating the impact of latex paint emission on IAQ. Small chamber experiments using stainless steel and painted and unpainted gypsum board substrates were conducted to determine the emission characteristics of latex paint. The emissions from the stainless steel were relatively short lived (3 to 4 days), whereas the emissions from gypsum board lasted for over 200 days. Because gypsum board is a common substrate for latex paint, all emission models were developed for the gypsum board substrates. The data from the small chamber tests led to the development of two empirical and two mass-transfer-based source emission models. Approximately 100 to 200 days of data were required to estimate the parameters required for the empirical models. Only 8 days of data were required to estimate the parameters for the mass-transfer-based models. The final models use paint formulation and mass transfer correlations to predict the emissions of the major individual volatile organic compounds emitted by latex paint.     

Symptoms, complaints, ocular and nasal physiological signs in university staff in relation to indoor environment - temperature and gender interactions

Symptoms, signs, perceptions, and objective measures were studied in university buildings. Two problem buildings with a history of dampness and complaints were compared with two control buildings. Health investigations among university staff were performed at the workplace (n = 173) including tear film stability [non-invasive break-up time (NIBUT) and self-reported break-up time (SBUT)], nasal patency (acoustic rhinometry), nasal lavage fluid analysis [NAL: eosinophil cationic protein (ECP), myeloperoxidase (MPO), lysozyme and albumin] and atopy by total serum IgE and IgE antibodies (Phadiatop). Exposure assessment included inspections, thermal and atmospheric climate at 56 points modelled for all work sites. Multiple regressions were applied, controlling for age and gender. Exposure differences between problem buildings and controls were small, and variations between rooms were greater. Workers in the problem buildings had more general and dermal symptoms, but not more objective signs than the others. Adjusted day NIBUT and SBUT increased at higher night air temperatures, with B (95% CI) 0.6 (0.04-1.2) and 1.3 (-0.02 to 2.5), respectively. Higher relative humidity at mean day air temperature <22.1 degrees C was associated with adjusted NIBUT and SBUT, with B (95% CI) 0.16 (0.03-0.29) and 0.37 (-0.01 to 0.75), respectively. Air velocity below recommended winter values and reduced relative humidity in the range of 15-30% were associated with dry air and too low temperature. PRACTICAL IMPLICATIONS: Thermal climate in university buildings may be associated with both perceptions and physiological signs. Reduced night time air temperature, increased difference in air temperature between day and night, and fast changes in air temperature might impair indoor environment. This may have implication for energy-saving policies. It might be difficult to identify the exposure behind, and find the reason why, some buildings are defined as 'problem buildings'.     

Building and Environment

This paper investigates the concern that green buildings may promote energy efficiency and other aspects of sustainability, but not necessarily the health and well-being of oc-cupants through better indoor air quality ( IAQ ) . We ask ten questions to explore IAQ challenges for green buildings as well as opportunities to improve IAQ within green buildings and their programs. Our focus is on IAQ, while recognizing that many factors influence human health and the healthfulness of a building. We begin with an overview of green buildings, IAQ, and whether and how green building certifications address IAQ.Next, we examine evidence on whether green buildings have better IAQ than comparable conventional buildings. Then, we identify so-called green practices and green products that can have unintended and unfavorable effects on IAQ. Looking ahead, we offer both immediate and longer-term actions, and a set of re-search questions, that can help green buildings to more effectively promote IAQ. This article supports a growing recognition of the importance of IAQ in green buildings, and the opportunities for improvements. As the World Green Building Council [ 95 ] and others have emphasized, people are the most valuable asset of or-ganizations, and efforts to improve IAQ can improve health, well-being, productivity, and profitability.     

Volatile organic compound emissions from latex paint--Part 2. Test house studies and indoor air quality (IAQ) modeling

Emission models developed using small chamber data were combined with an Indoor Air Quality (IAQ) model to analyze the impact of volatile organic compound (VOC) emissions from latex paint on indoor environments. Test house experiments were conducted to verify the IAQ model's predictions. The agreement between model predictions and experimental measurements met the American Society for Testing and Materials criteria for model verification in the room with the source and met most of the requirements in other rooms. The major cause of disagreement between the model predictions and the experimental data in the test house appears to be an inadequate sink model.     

The Influence of Office Furniture,Workstation Layouts,Diffuser Types and Location on Indoor Air Quality and Thermal Comfort Conditions at Workstations

Abstract Many factors affect the airflow patterns, contaminant removal efficiency and the indoor air quality at individual workstations in office buildings. The effects of office furniture design and workstation layouts on ventilation performance, contaminant removal efficiency and thermal comfort conditions at workstations were studied. The range of furniture configurations and environmental parameters investigated included: 1) partition heights, 2) partition gap size, 3) diffuser types, 4) supply air diffuser location relative to the workstation, 5) return air grill location relative to the workstation, 6) heat source locations, 7) presence of furniture, 8) supply air temperatures, 9) adjacent workstations, 10) contaminant source locations, 11) supply air flow rates, and 12) outdoor air flow rates. The tracer gas technique was used to study experimentally the relative impact of these parameters on the air distribution and ventilation performance, as well as contaminant removal efficiency. Thermal environmental parameters such as air velocity and temperature were monitored at several locations to characterize the impact of these parameters on the thermal comfort conditions. The results showed that the outdoor air flow rate had a significant influence on the mean age of air. The air distributions at all the workstations were good even when the supply air flow rate was relatively low (i.e 5 L/s). At the same time, most of the parameters tested had a significant influence on contaminant removal efficiency when there was a contaminant source present somewhere in the office.     

基于湿建材VOCs散发测试的室内空气质量标准探讨

为研究我国与国外相关室内空气标准中所控制VOCs指标的合理性,本文选取了5类常见的湿建材(内墙涂料、木器漆、防水涂料、胶粘剂、环氧地坪)共15种样品作为测试对象,在小型环境测试舱内测量样品的甲醛和TVOC散发率,并进行定性、定量分析。实验结果表明,湿建材的甲醛散发率比较低,内墙涂料、木器漆、万能胶、环氧地坪的TVOC散发率较高。进一步的分析显示,内墙涂料所散发的VOCs中不包含受控的挥发性有机污染物,而在其它湿建材测试中,甲苯、二甲苯、乙苯等高风险物质均被不同程度地检出,这表明TVOC散发率与湿建材的健康风险没有直接联系,我国相关室内空气质量标准中使用的TVOC限值有一定的局限性。     

Field Measurements of Ventilation and Ventilation Effectiveness in an Office/Library Building

Mechanical ventalation system performance involves the provision of adequate amuunts of outdoor air, uniform distribution of ventilation air within the occupied space, and the maintenance of thermal comfort. Standard measurement techniques exist to evaluate thermal comfort and air change rates in mechanically ventilated buildings; procedures to evaluate air distribution or ventilation effectiveness in the field are still being developed. This paper presents measuremetlts of air change rates and ventilation effectivenes in an office/library building in Washington, DC. The tracer gas decay technique was used to measure whole building air change rates. The air change rates during the measurement period were essentially constant at about 0.8 air changes per hour, somewhat below the design specification and above the minimum recmmmded in ASHRAE Standard 62-1989. Ventilation effectiveness was investigated at several locations within the building through the measurement of local tracer gas decay rate and mean local age of air. The ventilation effectiveness measurements serve as an investigation of the applicability of the m e a s u r r n procedures employed, providing insight into the measurement issue of establishing initial conditions, the spatial variation in test results within a building, and the repeatabildy between tests. The results of the ventilation effectiveness meusurements are consistent with good distrhtion of the outdoor air by the ventilation system and good mixing within the occupied space.     

Influences of the train-wind and air-curtain to reduce the particle concentration inside a subway tunnel

Subways are used widely for public transportation in major cities and require efficient ventilation systems to maintain indoor air quality in the subway tunnel. A subway tunnel was investigated numerically and experimentally to reduce the particle concentration in subway tunnels. The subway tunnel is 54-m long, 1.65-m high, and 2.5-m wide. The subway tunnel is one-quarter scale of a real subway tunnel. The tunnel has two U-type mechanical ventilation shafts. The steady three-dimensional airflow in the tunnel was analyzed using ANSYS CFX software to solve the Reynolds-averaged Navier–Stokes equations. The airflow in the tunnel and shafts was observed numerically using the train-wind and air-curtain. The effects of the train-wind, air-curtain, and electric precipitator were examined experimentally. The ventilation performance in the subway tunnel was observed with respect to the particle concentration in the tunnel. The numerical results suggest proper operating conditions for experimental analysis of the particle concentration. The average velocity of the airflow increases in the shaft when the velocity of the air-curtain increases. The particle concentration at the dust monitoring device after ventilation shaft 1 was reduced significantly in the tunnel when the air-curtain and train-wind were operated.