超大剂量6MeV电子束照射对大鼠脑Ca2+、Mg2+含量的影响

观察超大剂量6 MeV电子束照射对大鼠脑Ca2+、Mg2+含量的动态变化,探讨其在放射性脑损伤发病机制中的作用.对SD大鼠用6MeV电子线进行10Gy、20Gy和30Gy全脑单次照射,应用等离子直读光谱仪定量分析大鼠脑放射性损伤后不同时间、不同剂量脑组织中Ca2+、Mg2+含量的动态变化,用干-湿重法测定脑组织含水量.大鼠全脑受照射后,均存在脑组织中Ca2+含量升高、Mg2+含量下降和脑水肿的发生.其中20 Gy照射后24 h脑组织中Ca2+含量与对照组相比有显著升高(p＜0.05),Mg2+含量在照后7天与对照组相比有显著下降(p＜0.05).在照后7天,上述各指标变化的幅度为30Gy组＞20Gy组＞10Gy组.基于大鼠放射性脑损伤后脑组织中Ca2+、Mg2+含量发生的变化,探讨了电离辐射所致脑损伤的机理.     

The analysis of the insertion of UO2 microspheres in the gap between pellet and clad as a new design solution to increase the burnup of the nuclear fuel

The insertion of UO₂ microspheres (eventually graphite coated) in the gap between pellet-clad is observed to decrease substantially the clad hoop plastic strain concomitantly with the elimination of the rim effect at high burnup if low enrichment is used for the microspheres. Taking into account the special features of the specialized finite element code ELFIN'90 for the behavior of fuel elements, it was possible to introduce this new type of material viewed as a granular media. The results of the new code version ELFIN'MS applications to a PHWR fuel for a power ramp irradiation history show that the hoop plastic strain is reduced by about three times in comparison to standard fuel, and that the ridge phenomenon disappears. To establish critical plastic strain limit for irradiated clad failure onset, quantitative evaluations of iodine chemisorbtion on graphite and at the surface of the irradiated zircaloy, are presented. The indications on technology procedure are also discussed. Therefore, the insertion of 2–3 layers of UO₂ microspheres of 100 μm diameter, graphite coated to retain corrosive fission products for clad and with the diameter greater than the design gap, can be considered a design solution to increase the burnup of nuclear fuel.