制药行业BOM的数据库设计及算法的研究

物料清单（BOM）是ERP系统中极其重要的部分。制药行业的BOM除了具有BOM的通用性外，还具有本身的特点。该文在分析制药行业BOM特点的基础上，介绍了适合制药行业BOM的合理的数据库设计和高效的物料低位码计算算法、成品分解算法和任务分解算法，采用存储过程实现。     

粗糙Vague集（值）间k步相似度量新方法

对粗糙集、Vague集及粗糙Vague集的概念、知识表示方法进行了讨论,描述了粗糙Vague集的相关概念,在研究了粗糙Vague集相似性度量方法的基础上,提出了一种对踌躇度п_v（x）k步细化的k步相似度量新方法,并且研究了该方法的相关性质。进一步对k步相似度量在k趋向无穷时求极限,得出粗糙Vague集退化为模糊集的特例情况。     

Fast implementation of partial Gram-Schmidt algorithm using tree data structure with sequential row pointers data structure to solve structural problems (PGS)

In this paper, tree data structure with sequential row pointers data structure is developed and used to implement the Partial Gram-Schmidt triangularization algorithm. This algorithm is used to find the solution of linear equations arising from many structural and network problems where the original matrix is non-symmetric and highly sparse, that is, the ratio between zeros and nonzeros elements is very large. An algorithm is developed using the above data structure and results are compared with the method given in M.A. Ajiz, Incomplete Methods For Computer Structural Analysis, PhD Thesis, Queen's University Belfast, 1982 and Ajiz & Jennings, Int. J. Num. Meth. Engng., 20, 949–966, 1984. Conjugate gradients algorithm is used in conjunction with Partial Gram-Schmidt algorithm to obtain the solution of problems obtaining four figure accuracy.     

Implementation path and reference framework for Industrial Internet Platform (IIP) in product service system using industrial practice investigation method

With the development of intelligent sensing, edge computing, fog computing, cloud computing, parallel computing, smart grid, big data, block chain, 5G, cyber-physical systems, digital twins, machine learning and other technologies, the industrial internet has undergone control network stage, sensor network stage, internet stage, Internet of Things (IoT) stage, Industrial Internet of Things (IIoT) stage, and Industrial Internet (II) stage, etc. In the existing research, scholars focus on a local dot, such as: technology, function, elements and application based on industrial internet. However, there is a lack of an overall framework to study the top-level planning of Industrial Internet Platform (IIP) from a systematic perspective. On the other hand, there are few studies on the detailed path and steps for implementing IIP in a specific enterprise in a specific industry. The objective of this paper is to study a reference framework and industrial implementation path for IIP in product service system using industrial practice investigation method, which meets the needs of industry on the basis of existing theory and industrial practice, and to provide reference for government and industry planning, design, implementation and promotion of IIP. In addition, the proposed reference framework and industrial implementation for IIP in product service system can enhance the core value of the enterprise and increase benefits.     

三维原子场全息作用矢量用于HETP类抗艾滋病类药物活性定量构效关系研究

定量构效关系为药物设计和筛选提供相对简便途径并受到广泛重视。为更好模拟药物结构与活性间相关性,尝试采用本实验室新近提出三维原子场全息作用矢量,基于三种经典原子间静电、立体和疏水即非键作用方式,不借助任何实验参数对35个HETP类抗艾滋病药物进行定量活性构效关系。模型估计和交互校验复相关系数和标准偏筹分别为R_(cu)~2=0．882、Q_(?)~2 =0．812与RMSEE=0．43。模型具良好稳定性和预测力,表明此矢量在分子结构表征和生物活性预测的适应性。