多孔聚合物微球载体催化剂催化乙烯聚合研究

采用两步种子溶胀聚合制备了含有氰基官能团的多孔聚合物微球载体,经化学法修饰后再负载四氯化钛,制备了聚合物微球载体负载的Ziegler-Natta催化剂,研究了多孔聚合物微球载体催化剂催化乙烯聚合。结果表明:多孔聚合物微球载体颗粒规整、均一,催化剂形态良好,复制了载体的形貌;多孔聚合物微球载体催化剂催化乙烯聚合最高活性为45.0kg,聚合产物颗粒形态较规整,堆积密度可达0.33g/cm3,得到的聚乙烯为超高分子量聚乙烯,相对分子质量最高为4.8×106。     

新型TiO2/聚合物复合粒子的制备及在化妆品中的应用

本实验制备了一种新型结构的TiO2/聚合物复合粒子.采用种子溶胀法制备了苯乙烯-二乙烯基苯共聚微球,在其表面引入功能基马来酸酐(MAH),使TiO2与MAH键合均匀沉积在微球表面并制成多孔微球.探讨了功能基团MAH对TiO2在聚合物表面复合的影响.实验发现,TiO2与MAH以化学键相连,这提高了TiO2的分散性和复合的稳定性.当微球功能基MAH含量为15%时,可以得到TiO2以30～80nm均匀分散的复合微球.复合后的TiO2粒子具有优良的紫外吸收能力.最后,讨论了该复合粒子在化妆品中的应用.     

负载玫瑰香精多孔微球的制备及缓释性能研究

以分散聚合合成的单分散聚苯乙烯微球作为种子微球,采用两步种子溶胀法制备多孔聚苯乙烯-二乙烯苯微球,并吸附玫瑰香精制备了香精多孔微球。利用马尔文激光粒度仪、比表面积孔径分布测定仪(BET)、热重分析仪(TGA)、扫描电镜(SEM)对种子微球和多孔微球的粒径、比表面积和孔结构、缓释性能、表观形貌进行了分析表征。结果表明:种球的粒径随着分散介质中无水乙醇体积分数的增大而增加;随着溶胀剂邻苯二甲酸二丁酯(DBP)用量的增加,多孔微球的平均粒径变大,分布变宽;随着交联单体二乙烯苯(DVB)用量增加,多孔微球平均粒径减小,分布变窄;以甲苯为致孔剂制备的多孔微球单分散性最好。当V(DBP):m(种球)=3:1,V(DVB):V(苯乙烯)=4:0时,制备的多孔微球的平均粒径约为4μm。以此多孔微球负载玫瑰香精,可以减缓香精的释放速率,提高起始分解温度,实现对香精的缓释。     

单步种子溶胀法与二步种子溶胀法制备氯霉素分子印迹聚合物微球的比较

以聚苯乙烯乳液为种球、氯霉素为模板分子、甲基丙烯酸为功能单体、乙二醇二甲基丙烯酸酯为交联剂,采用单步种子溶胀法与二步种子溶胀法制备了单分散氯霉素分子印迹聚合物微球,用光学显微镜和扫描电镜对微球的形貌进行了表征,并用静态吸附实验考察了微球的吸附识别性能,结果表明,二步种子溶胀法制备的微球分散性、吸附识别性能最佳,平均粒径...     

单分散聚合物微球的制备及功能化研究进展

综述了单分散聚合物微球常用的制备方法(乳液聚合法、种子聚合法、分散聚合法、沉淀聚合法、悬浮聚合法和膜乳化法等),介绍了单分散聚合物微球的功能化研究进展,包括磁性微球、多孔微球、温度/pH响应微球、阳离子微球以及微球官能团化等等。最后提出了多种聚合方法的相互结合是制备功能性单分散聚合物微球的一大趋势,开发多功能的单分散聚合物微球、实现批量生产是其近期的重点研究方向。     

废橡胶制备多孔微球的方法

<正>授权公告号:CN 104151598B授权公告日:2017年11月3日专利权人:安徽世界村新材料有限公司发明人:李健、葛九敢、刘善和等本发明公开了一种废橡胶制备多孔微球的方法。该方法将废旧轿车轮胎胎面胶粉碎为颗粒并作为种球,经过两步种子溶胀法合成多孔橡胶微球。二次溶胀中单体聚合为三元乙丙橡胶,可促进多种橡胶的配合使用。本发明各步反应均在较温和条件下进行,改善了胶粉的表面性能。橡胶微球多孔状的表面形态有利于提高精细胶粉与其他物质的相容性,扩大了精细胶粉的应用范围。     

种子溶胀悬浮聚合法制备分子印迹聚合物微球的研究进展

分子印迹聚合物微球是一种具有特异性识别性能的新型高分子材料.种子溶胀悬浮聚合法所制备的印迹聚合物微球可应用于极性环境中,能够满足诸如酶模拟等实际应用环境的要求.本文综述了几种不同的制备分子印迹聚合物微球的种子溶胀悬浮聚合法,并对其研究方向做了展望.     

中空聚合物微球的制备——溶胀处理条件的影响

采用种子乳液聚合法合成不同核壳比的聚甲基丙烯酸（MAA）-丙烯酸丁酯（BA）一甲基丙烯酸甲酯（MMA）／聚苯乙烯（St）-丙烯腈（AN）核壳乳液,经碱／酸溶胀法处理制备了中空聚合物微球。结果表明,中空聚合物的形态不仅与核壳比有关,也与溶胀处理时碱的种类、温度、溶胀剂及其用量、乳液pH值等因素有关,当核壳比为1：10,溶胀剂用量为核壳乳胶粒质量的1.5倍时,可以得到最大中空度接近30％的中空聚合物微球。     

碱溶胀法制备核壳中空微球研究进展

综述了碱溶胀法合成核壳中空微球的国内外研究进展,重点介绍了核壳中空结构的合成以及各种因素如聚合物组成,碱处理条件、乳化剂用量、单体瞬时转化率以及玻璃化温度对微球形态的影响。     

载药多孔微球的吸附及缓释性能研究

采用改进的二步种子溶胀聚合法制得粒径15μm内的多孔聚合物微球,以Parsol1789为模型组分,研究了多孔聚合物微球的活性物吸附能力以及体外释放性能,重点研究了多孔微球的比表面积、孔径和粒径对微球吸附和释放速度的影响.结果表明,比表面积大的多孔微球具有更高的平衡吸附量,由于Parsol1789分子体积较大,孔径对吸附量和释放速率都表现出了较大的影响,而随着微球粒径的减小,Parsol1789呈现更快的释放速度.从Parsol1789的释放结果可以看出,10 h后约释放负载活性物总质量的90%左右.     

用作活性物载体聚苯乙烯-二乙烯苯多孔交联微球的悬浮聚合制备及表征

Functional porous microspheres used for the slow release carrier of actives in cosmetics or pharmaceuticals were prepared by modified suspension polymerization of styrene （ST） with divinylbenzene （DVB） in the presence of toluene, cyclohexanol and heptane as porogenic diluents. The use of ultrasonic dispersion decreases the beads＇ size and improves the uniformity. The effects of the porogen mixture, DVB content and solvent extraction on the surface performance of the synthesized beads were studied. The microspheres were characterized by scanning electron microscopy （SEM） and BET surface area determination. It was found that a great proportion of the non-solvating porogen increases the pore diameter and the specific surface area. High DVB concentration also results in the great specific surface area and porosity. When the ratio of toluene/cyclohexanol is 1：2, DVB content is at the range of 40%-60% and methylene chloride was used as extractant, the beads with good spherical shape and pore size were obtained. The prepared porous microspheres were applied as active carriers and showed satisfactory slow release effect. Over 10h constantly sustained release was observed in vitro releasing test for hydroquinone-loaded microspheres. Great surface area promoted high concentration of released hydroquinone.     

种子溶胀法制备聚甲基丙烯酸酯类微球

以分散聚合法制得的单分散聚苯乙烯微球为种球,采用改进的两步种子溶胀法制备了粒度均一、高交联、多孔的聚甲基丙烯酸缩水甘油酯-乙二醇二甲基丙烯酸酯微球,并系统探索了稳定剂种类和浓度、活化剂用量、溶胀倍数、致孔剂的种类及比例对微球形态和粒径分布的影响,同时用光学显微镜、扫描电镜、红外光谱及高效液相色谱对微球进行了表征。结果表明,以2μm和4μm的聚苯乙烯微球为种球,当活化剂与种球质量比为4,溶胀倍数为20~40倍,致孔剂为体积比为6∶4的环己醇和甲苯混合溶剂,以质量分数0.2%的羟丙甲基纤维素(以整个体系质量计,下同)为稳定剂时可制得粒径5μm和10μm的单分散高交联多孔的聚甲基丙烯酸酯类微球。     

聚合物-纳米无机粒子复合微球研究新进展

近年来,聚合物-纳米无机粒子复合微球相关的设计、制备、以及应用研究得到了科学界众多学者的广泛关注与探索。本文论述了单体聚合法制备聚合物-纳米无机粒子复合微球的研究近况,主要介绍了悬浮聚合、乳液聚合(微乳液聚合、Pickering乳液聚合、细乳液聚合、反相乳液聚合、无皂乳液聚合)、分散聚合及溶液聚合的制备方法。概述了聚合物-纳米无机粒子复合微球在生物医药、光电材料、保护涂层、催化等方面的应用,展望了聚合物-纳米无机粒子复合微球的发展趋势。     

反向悬浮聚合法制备载药淀粉微球的研究

以可溶性淀粉为原料,N,N′-亚甲基双丙烯酰胺(MBAA)为预交联剂,环氧氯丙烷(ECH)为交联剂,采用反相悬浮法制备了载药淀粉微球,以淀粉微球的平均粒径和溶胀度为指标,考察引发剂用量、MBAA用量、油水两相体积比、反应时间等因素对微球合成的影响。利用粒度分析仪、扫描电镜、红外光谱等对产物进行了表征。结果表明:淀粉微球的平均粒径随引发剂用量的增加先增大后减小,随反应时间的增加逐渐增大;溶胀度随引发剂用量的增加先增大后降低,随反应时间的增加降低。MBAA用量和油水比对淀粉微球的平均粒径和溶胀度影响较大。制备所得淀粉微球粒度分布范围较窄,球形圆整,表面粗糙多孔,可用作良好的药物载体和吸附剂。     

Preparation of uniform poly(glycidyl methacrylate) porous microspheres by membrane emulsification–polymerization technology

Uniform poly(glycidyl methacrylate‐divinyl‐benzene) (P(GMA‐DVB)) and poly(glycidyl methacrylate‐ethylene dimethacrylate) (P(GMA‐EGDMA)) porous microspheres with several 10 μm were successfully prepared by membrane emulsification–polymerization technology. Conventional suspension polymerization method was first investigated by examining the effects of recipe components on the morphologies of P(GMA‐DVB), including stabilizer, diluent, and crosslinker to select a optimum recipe. The membrane emulsification–polymerization process was developed to prepare uniform PGMA porous microspheres as the following: the oil phase composed of monomer, diluent and initiator was pressed through membrane pores into the aqueous phase to form uniform droplets, and subsequent suspension polymerization was carried out. GMA and 4‐methyl‐2‐pentanol in the selected recipe were relatively hydrophilic, and therefore oil phase could wet the hydrophilic glass membrane and bring about polydispersed droplets. However, when isooctane was added as a component of diluents, the uniform droplets could be prepared by membrane emulsification method. In the membrane emulsification–polymerization, the coagulation between microspheres obviously decreased while yield of microspheres slightly increased. To extend the application of PGMA, as a trail, uniform P(GMA‐EGDMA) porous microspheres were also successfully prepared by membrane emulsification–polymerization with a isooctane contained diluent, even though EGDMA was more hydrophilic than DVB. Therefore, recipe was found the important factor to prepare uniform PGMA porous microspheres using membrane emulsification–polymerization method. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 5018–5027, 2006     

单分散多孔聚合物微球的制备及其反相色谱应用

用分散聚合的方法制得单分散微米级聚苯乙烯微球(PS),以此聚苯乙烯微球作为种子,以邻苯二甲酸二丁酯为溶胀剂,苯乙烯为单体,二乙烯基苯为交联剂,甲苯为致孔剂,采用种子溶胀聚合的方法制得粒径分布较窄的多孔高交联的聚苯乙烯-二乙烯基苯微球(PS-DVB)。研究了交联剂与致孔剂的加入量对微球形貌、粒径及孔结构参数的影响。结果表明,所得多孔微球球形圆整,库尔特测得平均粒径为5.067~5.520μm,粒径分布窄,D90/D10为1.23~1.56,孔结构可控,并以此多孔微球作为反相色谱填料基质,理论塔板数每米可达6 000~15 000,可以用作高效液相色谱(HPLC)填料。     

环氧基多孔磁性复合微球的制备及性质

以聚醚为致孔剂,通过悬浮聚合法制备了表面带有环氧基的多孔磁性复合微球。用红外光谱(FTIR)、扫描电子显微镜(SEM)、磁强计(VSM)、压汞法等对其进行了表征,考察了分散剂质量分数对多孔磁性微球性能的影响。结果表明,该微球粒径为35～50μm,表面有不规则孔道,w(Fe3O4)≈15.8%,饱和磁化强度8.98 emu/g。水相中w(PVA)由1.5%升至3%时,微球平均粒径由130μm变为40μm,而平均孔径亦由144 nm降为39 nm。     

Study on preparation and process of poly(MMA-St) thermally expandable core-shell microspheres

Thermally expandable microspheres were synthesized by the suspension polymerization of methyl methacrylate (MMA) and styrene (St) in the presence of paraffin blowing agents. The effect of the monomer composition, the initiator, the blowing agent, the polymerization temperature on the morphology and structure of microspheres were studied. The results showed that AIBN initiated the water phase polymerization of MMA to form secondary polymer particles adsorbed on the surface of the microspheres. MMA diffused from the oil phase to the water phase, which accelerated the phase separation and facilitated the formation of core-shell microspheres. However, LPO could not initiate the water phase polymerization, the phase separation was slow and there was an intermediate state with a porous surface. When the boiling point of the blowing agent was lower than the polymerization temperature, the microspheres were porous and there were a large number of holes on the surface.     

分散聚合法制备微米级聚苯乙烯微球

简要评述了微米级聚苯乙烯 ( PS)微球的制备方法 ,并着重介绍了用分散聚合法制备 PS微球时单体浓度、介质、稳定剂、引发剂与温度、反应时间、搅拌速度、气氛等影响因素及微米级 PS微球的应用与发展。     

Influence of chelating agent and reaction time on the swelling process for preparation of porous TiO2 particles

This study aimed to describe the preparation and characterization of porous titanium oxide particles of narrow particle size distribution by a single-step swelling process of polystyrene template microspheres. In this research, different specific surface areas, porous structures and densities of porous titanium oxide particles had been synthesized with various experimental parameters. Two main parameters were tested and discussed: (1) acetylacetone amount (from 0 to 1 ml) and (2) reaction time (from 2 to 32 h). Polystyrene template particles were polymerized by emulsifier free-emulsion polymerization (a kind of polymerization method). For the swelling process to be successful, a chelating agent (acetylacetone) was added to delay the aqueous hydrolysis of titanium (IV) isopropoxide in the water phase. The influences of various reaction parameters on size, morphology, composition, specific surface area, porous structure and density of particles were investigated. The properties of particles were analyzed by scanning electron microscope, Brunauer–Emmett–Teller, Fourier transform infrared analysis, thermogravimetric analysis, powder X-ray diffraction, and specific gravity meter.