单托辊工艺皮带秤

本文重点介绍了模块化单托辊工艺皮带秤的结构组成及其功能特点,与其它秤架相比,这种秤架结构简单,安装方便,适用性及通用性较强,是一种新型的工艺秤秤架结构,应用范围很广。     

单托辊工艺皮带秤模块化

本文重点介绍了模块化单托辊工艺皮带秤的结构组成及其功能特点,与其它秤架相比,这种秤架结构简单,安装方便,适用性及通用性较强,是一种新型的工艺秤秤架结构,应用范围很广。     

西门子妙声力公司MSI单托辊皮带秤

首先叙述了西门子妙声力公司的简况和主要产品，然后介绍了该公司MSI单托辊秤的整体性能、秤架结构，最后着重对秤架特点进行了分析。     

皮带秤秤架结构新分类方法的研究

本文对各种秤架的响应特性曲线进行了分析,然后按特性曲线的形状对皮带秤秤架结构进行分类,有单杠杆式、悬臂式、双杠杆式和悬浮式等秤架。这种分类方法反映了秤架结构的内在特性,因而是一种科学的分类方法。     

ICS-FH型浮衡皮带秤的设计与应用——一种自由浮动的计量设备

皮带秤高精度测量的关键是称重桥架将皮带上的物料重量全部、准确的传递给称重传感器,传递过程没有任何干扰力。目前,多托辊皮带秤秤架结构有单杠杆式、双杠杆式、悬浮式等多种结构形式,称重传感器与秤架的连接多采用刚性连接,其中多数设有水平力、侧向力限位装置,这种限位连接形式存在一定的限制力、结构内应力,该限制力、结构内应力无法很好释放,容易产生过定位,干扰了重力的准确测量,特别是小重力或重力变化小的情况,干扰影响尤为突出,无法提供高精度的称重计量。     

瑞士哈斯勒公司VHRS皮带秤

我院在工程设计中引进了五台瑞士哈斯勒(HASLER)公司电子皮带秤。该公司是开创(K—TRON)跨国集团公司的一家子公司,主要从事动态称重产品的生产,重点产品有皮带秤、冲量流量计、固体物料质量流量计、皮带称重给料机、料斗秤配料系统、失重式给料机秤、磨机电耳等。哈斯勒公司的皮带秤类产品有单托辊秤、多托辊秤、烟草工业用     

160t铁水包主副钩天车技改电子秤的设计

本文简单介绍了行车电子秤常用的秤体结构形式,平衡架下面安装鱼背桥式传感器是一种常用的天车技改方案,并着重分析了南通宝钢钢铁有限公司160t铁水包主副钧天车技改电子秤的设计——采用超薄型轴座式称重传感器的设计解决平衡架下面无法安装鱼背桥式传感器的难题。     

复调法的原理与应用

一、提出问题的理由 标尺秤正确性的检修,或调整杠杆臂长,或调整游砣重量,或两者并用。调整游砣重量法,因其简单而被普遍采用。这种方法为空秤平衡,即加放砝码,拨动游砣,秤高加砣重,秤低减砣重,使秤平衡。但回空,则零点或低或高,必须再调试多次才能把秤调准。所以,称     

一种浮动自平衡皮带秤的原理及应用

皮带秤秤架结构主要有单杠杆式、双杠杆式、悬浮式等多种结构形式,荷重传感器与秤架的连接多采用刚性连接,其中多数设有水平力、侧向力限位装置,这种限位连接形式存在一定的限制力、结构内应力,该限制力、结构内应力无法很好释放,容易产生过定位,干扰重力的准确测量。而浮动自平衡秤架可以很好的避免上述缺陷,本文主要阐述这种浮动自平衡皮带秤的基本原理及其应用要求,从而保证皮带秤的高精度计量。     

500kg机械台秤示值误差测量结果的不确定度评定

机械台秤是利用不等臂杠杆原理工作。由承重装置、读数装置、基层杠杆和秤体等部分组成。读数装置包括增砣、砣挂、计量杠杆等。基层杠杆由长杠杆和短杠杆并列连接。称量时力的传递系统是:在承重板上放置被称物时的4个分力作用在长、短杠杆的重点刀上,由长杠杆的力点刀和连接钩将力传到计量杠杆重点刀上。通过手动加、减增砣和移动游砣,使计量杠杆达到平衡,即可得出被称物质量示值。机械台秤结构简单,计量较准确,只要有一个平整坚实的秤架或地面就能放置使用。对物品的承重计量使用方法简单,被广泛应用于农贸集市、商场、物资仓库和工厂企业等场所。本文针对500kg机械台秤示值误差测量结果进行不确定度评定。     

Adrenergic regulation of bone metabolism: possible involvement of sympathetic innervation of osteoblastic and osteoclastic cells

It has been demonstrated that human osteoblastic as well as osteoclastic cells are equipped with adrenergic receptors and neuropeptide receptors and that they constitutively express diffusible axon guidance molecules that are known to function as a chemoattractant and/or chemorepellent for growing nerve fibers. These findings suggest that the extension of axons of sympathetic and peripheral sensory neurons to osteoblastic and osteoclastic cells is required for the dynamic neural regulation of local bone metabolism. Recently, bone resorption modulated by sympathetic stimulation was demonstrated to be associated with ODF (osteoclast differentiation factor) and OCIF (osteoclastogenesis inhibitory factor) produced by osteoblasts/stromal cells. This review summarizes the evidence implicating sympathetic neuron action in bone metabolism. The possible function of osteoclastogenesis, which could result in the initiation of sympathomimetic bone resorption, is also discussed.     

Immunohistochemical localization of angiotensin II receptor types 1 and 2 in the mesenteric artery from spontaneously hypertensive rats

Angiotensin II plays a crucial role in the control of blood pressure, acting at AT1 or AT2 receptors, and can act as a potent vasoconstrictor of the peripheral vasculature inducing hypertrophy, hyperplasia, or both, in resistance arteries. The aim of the present study was to investigate whether the pattern of distribution of angiotensin AT1 and AT2 receptors on mesenteric artery sections differs in spontaneously hypertensive rats (SHR) versus their respective controls (Wistar-Kyoto [WKY] rats). Immunohistochemistry using anti-AT1 or anti-AT2 antibodies was performed on perfused-fixed/paraffin-embedded mesenteric arteries from SHR and WKY rats. 3,3'-Diaminobenzidine tetrahydrochloride (DAB; activated by hydrogen peroxide) staining revealed distinct AT1 and AT2 labeling of all artery layers (adventitia, media and intima) from WKY rats, whereas in SHR an abundant AT1 labeling was found in both intima and adventitia and a sparser labeling in the media. There was a vast reduction of AT2 labeling throughout all layers. These results suggest a crucial role for AT2 receptors in the pathogenesis of hypertension.     

Ovarian hormones and fasting differentially regulate pituitary receptors for estrogen and gonadotropin‐releasing hormone in rabbit female

To investigate the mechanisms by which caloric restriction affects reproductive function in female rabbits, we measured, in animals intact or ovariectomized (OVX) estrogen‐primed and fed ad libitum or fasted for 48 h, the adenohypophysial expression of estrogen receptor‐alpha (ESR1) and gonadotropin releasing hormone receptor (GnRHR) and the dynamic secretion of LH following GnRH stimulation. Fasting increased the number of GnRHR‐immunoreactive (‐IR) cells in intact animals, whereas reduced the density of ESR1‐IR cells in OVX rabbits. Estrogen priming decreased the number of ESR1‐IR cells in fasted and OVX animals. Ovariectomy increased the number of ESR1‐IR cells in fed rabbits, but caused an opposite effect in both fed and fasted animals treated with estrogen. Fasting down regulated the mRNA levels for ESR1 and GnRHR. Estrogen‐priming reduced the abundance for ESR1 mRNA in both fed and fasted rabbits, and that for GnRHR in fasted rabbits. Ovariectomy halved ESR1 mRNA levels independently of treatment and feeding condition, whereas increased (P < 001) that for GnRHR in estrogen‐primed rabbits. In all rabbits, an LH surge occurred 30 min after GnRH injection but the lowest levels were found in intact fasted rabbits and the highest in fasted, estrogen‐primed animals. The LH profile was similar in intact and OVX rabbits and neither fasting nor estrogen priming modified it. In conclusion, fasting differentially modifies the ESR1 and GnRHR expression in the pituitary, depending on the presence of gonadal hormones, indicating complex interactions between metabolic signals and ovarian steroids. Microsc. Res. Tech. 77:201–210, 2014. © 2013 Wiley Periodicals, Inc.     

Budding process during the organogenesis of the ventral prostatic lobe in mongolian gerbil

The prostate is a mammalian gland that shows a complex process of organogenesis. Here, a morphological study to characterize the organogenesis of the ventral prostate lobe in male gerbils was conducted. The urogenital sinus (UGS) was dissected out and processed for paraffin embedding. Histological sections were subjected to cytochemical, immunofluorescence, immunohistochemical, and three‐dimensional reconstruction techniques. We found that the first ventral buds emerged from the ventral urethral epithelium between the days 20 and 21 of prenatal life, reaching the ventral mesenchymal pad and initiating the branching process on the first day of postnatal life. The buds presented a V‐shaped elongation, suggesting that the smooth muscle layer (SML) plays an important role during budding events. Indeed, whereas the androgen receptor (AR) was preferentially found in the UGS mesenchyme (UGM), estrogen receptor alpha (ERα) was localized in both the UGM and in the emerging buds. This study characterized the morphological aspects of the budding process in a different rodent from rat and mice, serving as a new model for future studies on developmental biology of the prostate. Microsc. Res. Tech. 77:458–466, 2014. © 2014 Wiley Periodicals, Inc.     

Image correlation microscopy for uniform illumination

Image cross-correlation microscopy is a technique that quantifies the motion of fluorescent features in an image by measuring the temporal autocorrelation function decay in a time-lapse image sequence. Image cross-correlation microscopy has traditionally employed laser-scanning microscopes because the technique emerged as an extension of laser-based fluorescence correlation spectroscopy. In this work, we show that image correlation can also be used to measure fluorescence dynamics in uniform illumination or wide-field imaging systems and we call our new approach uniform illumination image correlation microscopy. Wide-field microscopy is not only a simpler, less expensive imaging modality, but it offers the capability of greater temporal resolution over laser-scanning systems. In traditional laser-scanning image cross-correlation microscopy, lateral mobility is calculated from the temporal de-correlation of an image, where the characteristic length is the illuminating laser beam width. In wide-field microscopy, the diffusion length is defined by the feature size using the spatial autocorrelation function. Correlation function decay in time occurs as an object diffuses from its original position. We show that theoretical and simulated comparisons between Gaussian and uniform features indicate the temporal autocorrelation function depends strongly on particle size and not particle shape. In this report, we establish the relationships between the spatial autocorrelation function feature size, temporal autocorrelation function characteristic time and the diffusion coefficient for uniform illumination image correlation microscopy using analytical, Monte Carlo and experimental validation with particle tracking algorithms. Additionally, we demonstrate uniform illumination image correlation microscopy analysis of adhesion molecule domain aggregation and diffusion on the surface of human neutrophils.     

双承载器数字指示轨道衡检定方法的研究

本文对双承载器数字指示轨道衡的工作原理、结构和计量性能进行了分析,提出了双承载器数字指示轨道衡的检定方法,从而对国家计量检定规程JJG 781-2002《数字指示轨道衡》检定规程的修订起到了参考和指导作用。     

Image mean square displacement to study the lateral mobility of Angiotensin II type 1 and Endothelin 1 type A receptors on living cells

The lateral mobility of membrane receptors provides insights into the molecular interactions of protein binding and the complex dynamic plasma membrane. The image mean square displacement (iMSD) analysis is a method used to extract qualitative and quantitative information of the protein diffusion law and infers how diffusion dynamic processes may change when the cellular environment is modified. The aim of the study was to describe the membrane diffusing properties of two G‐protein‐coupled receptors namely Angiotensin II type 1 (AT₁) and Endothelin 1 type A (ET_A) receptors and their corresponding receptor–ligand complexes in living cells using total internal reflection fluorescent microscopy and iMSD analysis. This study showed that both AT₁ and ET_A receptors displayed a mix of three modes of diffusion: free, confined, and partially confined. The confined mode was the predominant at the plasma membrane of living cells and was not affected by ligand binding. However, the local diffusivity and the confinement zone of AT₁ receptors were reduced by the binding of its antagonist losartan, and the long‐range diffusion with the local diffusivity coefficient of ET_A receptors was reduced upon exposure to its antagonist BQ123. To the best of our knowledge, this is the first study addressing the protein diffusion laws of these two receptors on living cells using total internal reflection fluorescence microscopy and iMSD.     

Receptor autoradiography and 2-deoxyglucose techniques in neuroscience

The use of the receptor autoradiography and 2-deoxyglucose (2-DG) techniques in neuroscience are reviewed. Receptors and other binding sites can be visualized autoradiographically in microtome tissue sections after labelling with radioligand in vivo or in vitro. Autoradiograms are generated by apposition of the labelled tissue to photographic emulsions. Combined with computerized image analysis, this technique can be used to analyse and quantify the microscopic distribution of receptors and receptor alterations associated with lesions or disease in human and animal tissues. The 2-DG technique permits microscopic analysis of modifications in brain glucose utilization induced by physiological and pharmacological manipulations. Limitations of these techniques and attempts to optimize their resolution are also discussed.     

雌激素受体电镜定位的微波照射技术

将微波照射与电镜细胞化学技术相结合确定雌激素受体在细胞内的位置。在样品的固定、包埋、聚合及孵育过程中,使用改进的微波照射技术,既提高了样品的制备质量,又将样品制备时间缩短到原来的1/3。