A digital microfluidic droplet generator produces self-assembled supramolecular nanoparticles for targeted cell imaging

Controlling the size distribution of polymer-based nanoparticles is a challenging task due to their flexible core and surface structures. To accomplish such as task requires very precise control at the molecular level. Here we demonstrate a new approach whereby uniform-sized supramolecular nanoparticles (SNPs) can be reliably generated using a digital microfluidic droplet generator (DMDG) chip. A microfluidic environment enabled precise control over the processing parameters, and therefore high batch-to-batch reproducibility and robust production of SNPs with a very narrow size distribution could be realized. Digitally adjustment of the mixing ratios of the building blocks on the DMDG chip allowed us to rapidly scan a variety of synthesis conditions without consuming significant amounts of reagents. Nearly uniform SNPs with sizes ranging from 35 to 350?nm were obtained and characterized by transmission electron microscopy and dynamic light scattering. In addition, we could fine-tune the surface chemistry of the SNPs by incorporating an additional building block functionalized with specific ligands for targeting cells. The sizes and surface properties of these SNPs correlated strongly with their cell uptake efficiencies. This study showed a feasible method for microfluidic-assisted SNP production and provided a great means for preparing size-controlled SNPs with desired surface ligand coverage.     

聚酰亚胺气体分离膜

介绍了一种新型的气体分离膜材料－－聚酰亚胺，对其发展历史，合成，制膜及气体分离的应用研究了作评术，从四个方面讨论了聚酰亚胺膜的气体透过机理。并与普通膜材料进行了比较，指出了该膜材料的广阔发展前景。     

Two-dimensional self-organization of gold nanoparticles on supramolecular aggregates

Alkanethiol-capped gold (Au) nanoparticles, dispersed in toluene and spin-coated on atactic polystyrene films that are themselves spin-coated on fused quartz plates, self-assemble into a characteristic two-dimensional pattern-a network of the Au-thiol nano-composite separating polystyrene 'islands' of dimensions around 200 nm. This pattern changes on varying the concentration of the nanoparticles in the coating solution, evolving into the network from isolated nanoparticle clusters, and then going over to a distribution of 'pinholes' on a surface covered by the nano-composite, resembling a partially wetted surface with near-full coverage. Study of the pristine polystyrene surface reveals a pattern of low-cohesion regions separating 'islands' of polystyrene, where the latter are known to be supramolecular aggregates. It is suggested that these regions play the role of low-resistance channels to the flow of the nano-composite during spin coating.     

纳米复合滤膜

介绍了纳米复合滤膜的优异性能．综述了纳米复合滤膜的发展现状．     

炭分离膜

炭分离膜作为一种特殊的炭分子筛,是一种新型的由炭素材料构成的具有分离功能的无机膜。最初的炭膜是ＡｓｈＲ等人于1973年以石墨化炭黑为原料经压制而成的平板膜。与传统的有机膜相比较,炭膜具有耐高温,高稳定性,高选择性,高渗透性,高分离能力,机械强度好以及清洁状态好等     

膜法有机蒸气回收系统在工业中的应用

介绍了膜分离技术在有机蒸气回收中应用的工作原理,工艺设计特点和要求等,针对目前国外各个膜公司使用膜技术回收有机蒸气的工艺设备过程进行了分析,同时也介绍了大连化学物理研究所生产的膜分离装置在烯烃回收过程中的应用情况。     

Centrifugal membrane and density separation: A new spin on membrane fouling

In this article, a team of researchers from the University of Victoria, BC, describe a novel approach to membrane separation which utilises a spinning centrifuge to reduce membrane fouling. The research group report that this method can result in higher flux due to decreases in particulate fouling and concentration polarisation. Work is already underway to identify possible applications for this new and promising technique, with applications of CMDS for the treatment of industrial waste and process waters under close scrutiny.     

用于氧氮分离促进输送膜的研究

报道对氧的促进输送膜的研制和膜的性能测定工作以Ｃｏ（３ＦＳａｌｅｎ）为氧载体，用简便的方法制备了聚砜－硅橡胶－氧载体复合膜；研究了制备方法和制备条件对膜渗透和分离性能的影响实验结果表明，促进输送膜能有效地在提高氧氮分离系数αＯ／Ｎ的同时，也提高了膜对氧的透气速率ＰＯ．采用混合固体氧载体的制膜方法也有独特的优点．     

Chitosan-based membrane chromatography for protein adsorption and separation

A chitosan-based membrane chromatography was set up by using natural chitosan/carboxymethylchitosan (CS/CMCS) blend membrane as the matrix. The dynamic adsorption property for protein (lysozyme as model protein) was detailed discussed with the change in pore size of the membrane, the flow rate and the initial concentration of the feed solution, and the layer of membrane in membrane stack. The best dynamic adsorption capacity of lysozyme on the CS/CMCS membrane chromatography was found to be 15.3 mg/mL under the optimal flow conditions. Moreover, the CS/CMCS membrane chromatography exhibited good repeatability and reusability with the desorption efficiency of ~ 90%. As an application, lysozyme and ovalbumin were successfully separated from their binary mixture through the CS/CMCS membrane chromatography. This implies that such a natural chitosan-based membrane chromatography may have great potential on the bioseparation field in the future.     

聚苯胺气体分离膜研究进展

介绍了聚苯胺(PANI)的结构、合成方法及其在气体分离领域的研究进展,综述了PANI气体分离膜的制备途径、掺杂过程和掺杂剂对PANI膜气体透过性能的影响.指出了研究中存在的问题,并对研究方向进行了预测.     

陶瓷-Teflon AF2400复合油气分离膜组件

用陶瓷超滤膜管和Teflon AF2400溶液制备陶瓷管-Teflon AF2400复合膜.测试了该复合膜组件对H2,CO,CO2,CH4,C2H6,C2H4,C2H2七种故障气体的脱气性能,并与GP100聚四氟乙烯毛细管和聚酰亚胺(PI)平板膜进行了比较.结果表明,陶瓷管-Teflon AF2400复合膜组件可在10 h内实现7种故障特征气体的油气平衡,远远快于GP100和PI膜.该组件可以在500 kPa的压力下长时间正常工作,能够满足变压器油中溶解气体在线监测的需要.     

Easy access to selective binding and recyclable separation of histidine-tagged proteins using Ni<Superscript>2+</Superscript>-decorated superparamagnetic nanoparticles

The development of simple techniques for the separation and purification of recombinant proteins plays an important role in many of the advancements made in biotechnology and nanotechnology. Herein, we report an easy method for the efficient purification of polyhistidine affinity-tagged (His-tagged) proteins by using Ni²⁺-decorated superparamagnetic particles. Monodisperse Ni_0.3Fe_0.7Fe₂O₄ nanoparticles were prepared via a facile and economical one-pot hydrothermal process. Owing to the characteristic molecular recognition ability between nickel(II) ions and the polyhistidine affinity tag, the nanoparticles could be successfully employed to selectively bind and separate His-tagged cyan fluorescent protein (CFP) from an E. coli cell lysate in a recyclable process. Moreover, by changing the divalent metal precursors, various other metal-decorated magnetic nanoparticles can be obtained. This approach offers the possibility of constructing metal-decorated nanoparticles through a simple method and will be highly beneficial in further applications of nanoparticle-based technologies.      

有机蒸气分离膜的应用

介绍了有机蒸气分离膜的分离原理，并分别介绍了有机蒸气分离膜在石油化工和聚氯乙烯行业中的应用．     

A study of separation by the direct-contact membrane distillation process

The flux of permeate in the separation by the direct-contact membrane distillation process as a function of membrane characteristics and operating conditions was considered. The expressions describing the vapor transfer through a hydrophobic membrane, the temperature at the surface of the membrane, and changes of temperature and concentration solutions along the module in the countercurrent device were derived and proposed. The theoretically predicted results show about 85–90% agreement with the experimental data. The utility of equations in the separation technology was pointed out.