Assessing children's states of mind: A multitrait, multimethod study.

There is growing interest in assessing the positive and negative cognitions of children and adults alike. Much of this interest is attributable to the States of Mind (SOM) model, which relates the balance of positive and negative thoughts to psychological adjustment (R. M. Schwartz and G. L. Garamoni; see records 75:2138 and 79:28228). However, the validity of a central assumption of the SOM model and several critical methodological and psychometric questions must be considered when applying the SOM model to children. In a sample of 34 7- to 10-year-olds, 35 11- to 14-year-olds, and 40 undergraduates, we used four assessment methods to examine the effects of age, measurement method, and self- versus other-reference on SOM ratios. Results indicated that SOM ratios significantly varied depending on measurement method and the self- versus other-reference condition. Age did not significantly influence SOM ratios, suggesting that the set point specified by the SOM model is applicable to children. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The taxonicity of schizotypy: A replication.

P. E. Meehl's model (1962, 1990) of schizotypy and the development of schizophrenia implies that the structure of liability for schizophrenia is dichotomous, hypothesizing that a "schizogene" determines one's membership in a latent class (or taxon; P. E. Meehl & R. R. Golden, 1982). The present study sought to replicate earlier findings concerning the taxonic latent structure and general population base rate of schizotypy (M. F. Lenzenweger & L. Korfine, 1992). P. E. Meehl's (1973; P. E. Meehl & R. R. Golden, 1982) MAXCOV-HITMAX taxometric analytic procedures were applied to a subset of items from the Perceptual Aberration Scale (PAS; L. J. Chapman, J. P. Chapman, & M. L. Raulin, 1978), a prominent psychometric index of schizotypy, derived from a new randomly ascertained nonclinical university sample (N?=?1,646). Consistent with the authors' previous results as well as Meehl's conjectures, the data strongly suggest that schizotypy, as assessed by the PAS, is taxonic at the latent level with a low general population taxon base rate (i.e.,     

Familial brain wave patterns: study of a 12-sib family

To identify peptide-specific antibodies which define sperm surface antigens, hybridomas were derived from the splenocytes of mice immunized with swollen human spermatozoa which had been subjected to limited proteolytic cleavage under reducing conditions prior to immunization. A total of 13.7% of the hybrid clones secreted antibodies which reacted with deglycosylated human seminal plasma glycoproteins when screened by an ELISA. A monoclonal antibody, designated mAb 4A8 sp., specifying a peptide epitope of human epididymal and a sperm surface glycoprotein was selected which inhibited human sperm-egg binding in a dose-dependent manner, and totally blocked sperm penetration in vitro. This inhibition did not result from an effect of the antibody on the motility of spermatozoa, nor was it due to premature induction of the acrosome reaction. Exclusion of oligosaccharide chains by chemical hydrolysis with trifluoromethane sulphonic acid (TFMS), enzymatic degradation and binding of lectins, did not abrogate the reactivity of mAb 4A8 to the cognate epitope whereas antibody binding was precluded upon digestion with proteolytic enzymes. In Western immunoblots of human seminal plasma glycoproteins, the antigen presented as a set of immunoreactive polypeptides, a major glycoprotein of M(r) 78 kDa and less prominent bands of M(r) 56 and 44 kDa. Immunocytochemical staining of a number of human reproductive and somatic tissues revealed strong immunostaining of the luminal epithelium of the epididymis as well as of spermatozoa in the lumen. Immunolocalization to the plasma membrane of ejaculated human spermatozoa was demonstrated by immunofluorescence, although on undigested spermatozoa the antigen epitope was less accessible. Upon capacitation the antigen persisted on the sperm surface and was present on the head of capacitated acrosome-intact spermatozoa. The pronounced peripheral immunostaining of the sperm head was accentuated after DTT/trypsin treatment, implicating the dynamic accessibility of the epitope on the plasma membrane of capacitated spermatozoa. It is suggested that the protein in question appears on the sperm membrane as a consequence of its modification in the epididymis (insertion and processing), and may be involved in the processes leading to sperm attachment and interaction with the human zona pellucida.     

Familial cancer of the ovary. A family with 6 index cases

Greggi and Kerlikowske have worked out that a woman has a 1.4% chance of developing ovarian cancer during her life. When cancer of the ovary is found, 5 to 10% of these cases have a familial form of this pathology. Thus there are some hereditary forms of cancer of the ovary and Lynch has demonstrated that there are three types of hereditary associations with ovarian neoplastic pathology: specific familial cancer of the ovary, cancer of the ovary associated with endometrial cancer and with non-polypoidal cancer of the caecum and rectum, cancer of the ovary associated with cancer of the breast. The clinical material we are presenting here is of the first type of association and we are reporting the study of a family in which 6 members in two generations had cancer of the ovary and of whom one had cancer of the breast as well. Familial cancer of the ovary shows different characteristics coming on as it does earlier (ten years earlier) and with a shorter length of survival (1.8 as against 5 years). The risk of the next generation having ovarian neoplastic pathology is clear because there is a 50% chance in a patient who has a history of cancer of the ovary in at least two first degree relatives. For most daughters when this type of familial cancer is found it is justifiable to carry out prophylactic oophorectomy from the age of 35 year onwards. Particular supervision should be carried out for patients who are members of a family where 2 index cases have been found within 20-35 years.(ABSTRACT TRUNCATED AT 250 WORDS)     

The latent structure of schizotypy: I. Premorbid indicators of a taxon of individuals at risk for schizophrenia-spectrum disorders.

A taxometric analysis (R. R. Golden & P. E. Meehl, 1979) was conducted to test the hypotheses that liability for schizophrenia-spectrum disorders is dichotomously distributed and that this liability can be detected premorbidly with behavioral indicators analogous to many of the criteria for schizotypal personality disorder. Behaviors were assessed in 207 offspring of schizophrenic mothers and 104 matched offspring of normal parents in 1962, when participants' mean age was 15 years. Diagnoses on the basis of the Diagnostic and Statistical Manual of Mental Disorders (3rd ed., rev.; American Psychiatric Association, 1987) were made in 1986–1989, when participants were nearly through the risk period for developing schizophrenia. The aggregation of indicators was consistent with a bimodal latent liability distribution. Membership in the schizotypal class was a sensitive and specific predictor of the emergence of schizophrenia-spectrum disorders in adulthood. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Perceptual organization and schizotypy.

The preattentive visual information processing of hypothetically psychosis-prone college Ss was evaluated using 3 different paradigms: target detection (n?=?57), visual suffix effect (n?=?57), and configural superiority effect (n?=?68). It was hypothesized that anhedonic Ss would show the same perceptual organization deficits reported in process schizophrenics and that perceptual aberration-magical ideation Ss and depressed Ss would perform similarly to control Ss. In each study, anhedonics performed similarly to each comparison group, even though there was adequate power to detect performance differences if they existed. A framework for understanding the visual information-processing deficits of schizophrenics and high-risk Ss is proposed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Validity of students' evaluations of college teaching: A multitrait–multimethod analysis.

College instructors in 329 classes evaluated their own teaching effectiveness with the same 35-item rating form used by their students. There was student–instructor agreement in courses taught by teaching assistants (r?=?.46), undergraduate courses taught by faculty (r?=?.41), and graduate level courses (r?=?.39). Separate factor analyses of the student and instructor ratings demonstrated that the same 9 evaluation factors (e.g., work load, organization, interaction) underlay both sets of ratings. A multitrait–multimethod analysis supported convergent and divergent validity of these rating factors. Not only were correlations between student and instructor ratings on the same factors statistically significant for each of 9 factors, but correlations between their ratings on different factors were low. Findings demonstrate student–instructor agreement on evaluation of teaching effectiveness, support the validity of student ratings for both graduate and undergraduate courses, and emphasize the importance of using multifactor rating scales derived through the application of factor analysis. (28 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Hedonic capacity and schizotypy revisited: A taxometric analysis of social anhedonia.

P. E. Meehl (1962) originally conjectured that hedonic capacity was an indicator of the latent class or taxon of schizotypy. However, P. E. Meehl (1989, 1990) subsequently diminished the role of hedonic capacity in his theory, indicating that hypohedonia is one of a dozen normal-range (nontaxonic) individual-differences factors that may potentiate the expression of schizophrenia. This dimensional-only view of hedonic capacity was tested by applying taxometric procedures to the Revised Social Anhedonia Scale (RSAS; M. L. Eckblad, L. J. Chapman, J. P. Chapman, & M. Mishlove, 1982) in a sample of college students (N?=?1,526). Analyses indicated that the construct measured by the RSAS is taxonic in nature with a base rate approximating .10. These data are interpreted in the context of other findings suggesting that social anhedonia is an indicator of schizotypy. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Longitudinal stability of personality traits: A multitrait–multimethod–multioccasion analysis.

The longitudinal stability of personality was investigated in a group of several hundred adults who were rated by themselves, their marriage partners, and their acquaintances in 1935-1938 and by themselves and their marriage partners in 1954-1955. For both men and women, there were very similar factorial structures in all five sources of ratings. Individual differences in neuroticism, social extraversion, and impulse control had reasonably high levels of longitudinal stability over a 19-year period. Both the synchronic and diachronic correlations converged across methods and discriminated among traits. Self-report personality inventory data available in 1935-1938 and 1954-1955 provided corroborating evidence of the longitudinal and methodological robustness of personality traits. In data gathered on the same panel in 1980-1981, the questionnaire and the life history correlates of neuroticism and social extraversion displayed patterns indicative of temporal stability, methodological convergence, and discrimination among constructs. The data of this longitudinal study carried out over five decades strongly indicate that there is a set of personality traits that are generalizable across methods of assessment and are stable throughout adulthood. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Familial Hodgkin's disease and associated cancer. A clinical-pathologic study

The etiology of Hodgkin's disease is complex, as is evident in studies suggesting the importance of horizontal transmission, occupational factors, racial and ethnic background, and familial, genetic factors, or both, including HL-A associations. The present study is of a remarkable kindred in which Hodgkin's disease was histologically verified in two sibships involving second-cousins related through maternal great-grandparents. Cancer of the lung, breast, endometrium, ovary, pancreas, and brain, as well as leukemia and Wilms' tumor, occurred in first and second-degree relatives of the Hodgkin's patients. HL-A haplotypes in patients with Hodgkin's disease in this family showed HL-AB5 or HL-ABW35, an association confirmed in other reports. The findings of associated malignant neoplasms in familial Hodgkin's disease, here and elsewhere in the literature, suggest that in the quest for etiology of Hodgkin's disease one must view the disorder eclectically, with a painstaking search for multiple etiologies, genetic and environmental.     

Psychometric detection of schizotypy.

Genetic studies of typical schizophrenia require accurate means for the detection of carriers of the heritable diathesis. Psychometric methods have been developed, often for studying psychosocial transmission of schizophrenia, that might be useful for genetic studies. Studies of schizotypy detection using the Goldstein-Scheerer Object Sorting Test, Rorschach technique, TAT, and MMPI are reviewed. Most studies suffer from serious conceptual and methodological flaws that have made replication a rarity. Recent approaches emphasizing clinical signs and symptoms that bear a close content relationship to the typical schizophrenic syndrome are asserted to be more likely to bear fruit. (1? p ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Short-term family intervention: A therapy outcome study.

Attempted to modify the destructive communication patterns of delinquent families by systematically shaping in behaviors characteristic of adaptive family systems (increased reciprocity, greater activity, and increased clarity). Based on direct observation of family interaction in a discussion task with 20 teenage delinquents and their families, results indicate a significant change in the 4 interaction measures, while 2 indexes of questionnaire agreement remained unchanged. Use of a rigorous experimental design that controlled for pretest sensitization, maturation, and nonspecific professional attention demonstrated that these changes did not occur as a function of extraneous variables. The need for rigorous process research regarding the characteristics of specific target populations coupled with equally sound outcome research that can then evaluate change within these populations is emphasized by the results. (35 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Confirming the latent structure and base rate of schizotypy: A taxometric analysis.

P. E. Meehl's (1962, 1990) model of schizotypy and the development of schizophrenia implies that the structure of liability for schizophrenia is dichotomous and that a "schizogene" determines membership in a latent class, or taxon (Meehl and R. R. Golden, 1982). The authors sought to determine the latent structure and base rate of schizotypy. They applied Meehl's (1973) MAXCOV-HITMAX taxometric analytic procedures to a subset of items from the Perceptual Aberration Scale (PAS; L. J. Chapman et al, 1978), a prominent psychometric index of schizotypy, derived from a randomly ascertained nonclinical sample (N?=?1,093). The results, in accordance with Meehl's conjectures, strongly suggest that schizotypy, as assessed by the PAS, is taxonic at the latent level with a general population taxon base rate of approximately .10. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Familial antecedents of young adult health risk behavior: A longitudinal study.

With a sample of 116, the authors asked how characteristics of the family, rated by adolescents, predicted health risk behavior at young adulthood 6 years later and whether adolescent and young adult personal and emotional functioning mediated these relationships. The authors also explored the consistency of relationships among these variables across 4 types of families: balanced, traditional, disconnected, and emotionally strained. The family variables significantly predicted young adult health risk behavior over time and functioning at adolescence and young adulthood did not serve as a mediator. The family model operated well in 3 of the 4 family contexts; it failed to operate among offspring from disconnected families. Characteristics of the family affect the display of health risk behavior when offspring come from families that have well-defined and coherent family structures. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Psychometric schizotypy and motor performance.

Motor abnormalities have long been a focus in discussions of schizophrenia. The present study used a newly developed line drawing task to examine fine motor performance and psychometrically assessed schizotypy in a large, randomly ascertained sample of young adults (N = 120) with no history of psychosis. Poor motor performance on the line drawing task, indexed by root-mean-square error (RMS), was significantly related to 4 separate psychometric measures of schizotypy in the overall sample. The psychometric schizotypy-RMS association remained significant for 2 of the schizotypy measures even when the effects of intellectual functioning, mental state factors, and sustained attention were statistically controlled in a regression analysis. The status of the line drawing index as a schizophrenia liability measure is discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Semantic ambiguity resolution in positive schizotypy: A right hemisphere interpretation.

Positive schizotypal traits have been associated with right hemisphere activation. Previous research has indicated that the left and right hemispheres differ in their processing of semantic ambiguity; specifically, given sufficient time, the left hemisphere primes dominant meanings and inhibits subordinate meanings, and the right hemisphere primes both dominant and subordinate meanings. The authors examined whether individuals who differed in positive schizotypy demonstrated different patterns of priming on a semantic ambiguity task, reflective of differences in hemispheric activation. Individuals low in schizotypy demonstrated the expected pattern of priming the dominant meaning while inhibiting the subordinate meaning. Individuals high in schizotypy demonstrated similar priming of the dominant meaning but no inhibition of the subordinate meaning. The role of this failure of inhibition in the generation of schizotypal thought is discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Construct validity of psychopathy in a female offender sample: A multitrait–multimethod evaluation.

The authors examined the construct of psychopathy as applied to 103 female offenders, using the multitrait-multimethod matrix proposed by D. T. Campbell and D. W. Fiske (1959). Instruments used in the study included the following: (a) Antisocial Scale of the Personality Assessment Inventory (L. C. Morey, 1991); (b) Psychopathy Checklist–Revised (R. D. Hare, 1990); and (c) Antisocial scale of the Personality Disorder Examination (A. W. Loranger, 1988). Criterion-related validity was also evaluated to determine the relationship between psychopathy and staff ratings of aggressive and disruptive behavior within the institution. Results revealed significant convergence and divergence across the instruments supporting the construct of psychopathy in a female offender sample. The measures of psychopathy demonstrated moderate convergence with staff ratings of violence, verbal aggression, manipulativeness, lack of remorse, and noncompliance. It is interesting to note that an exploratory factor analysis of the PCL-R identified a substantially different factor structure for women than has been previously found for male psychopathy. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Familial predisposition for degenerative disc disease. A case-control study

STUDY DESIGN: This case-control study was undertaken to determine if relatives of patients who had been admitted for surgery for degenerative disc disease-related problems were at increased risk for lower back pain or sciatica. OBJECTIVES: To determine if familial factors play a role in placing a person at risk for development of degenerative disc disease of the lumbar spine. SUMMARY OF BACKGROUND DATA: It is known that smoking and various occupational factors can place a person at risk for degenerative disc disease problems. It is not known if a familial predisposition may also exist. METHODS: The family members and relatives of 65 patients who had undergone surgery for lumbar degenerative disc disease were interviewed with a standardized questionnaire and compared with a control group of 67 patients who had been admitted to hospital for non-spine-related orthopedic procedures. The same interview and standardized questionnaire was used for both groups by a single observer. RESULTS: In the study group of 65 patients who had undergone surgery for degenerative disc disease, 44.6% were noted to have a positive family history, whereas 25.4% of the patients in the control group had a positive family history. Eighteen and one-half percent of relatives in the study group had a history of having spinal surgery, compared with only 4.5% of the control group. CONCLUSIONS: The results indicate that a familial predisposition to degenerative disc disease can exist along with other risk factors.     

Familial correlations and X-linked genes: A comment.

Presents a simpler alternative to H. Thomas's (see record 1983-25050-001) formula for the phenotypic correlation among family members when a trait is affected by an X-linked gene. The present author suggests that the ordering of phenotypic familial correlations may not be entirely hopeless as a source of evidence for X linkage. (4 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Structure and validity of parent and teacher perceptions of children's competence: A multitrait–multimethod–multigroup investigation.

Parents and teachers completed their respective versions of S. Harter's ( 1985b) Rating Scale of Children's Actual Behavior to assess 5 domains of competence in 321 3rd- and 403 6th-grade children. Peers completed a peer nomination index of multiple competencies. Confirmatory factor analyses revealed 5 factors in both the teacher and parent scales: Academic Competence, Social Acceptance, Athletic Competence, Physical Appearance, and Behavioral Conduct. Two higher order factors also emerged: a Well-Behaved/Good Student factor and an Athletic/Attractive/Popular factor. All 5 subscales of the teacher and parent scales manifested a high degree of discriminant validity. Significant levels of convergent validity emerged for most of these subscales. (PsycINFO Database Record (c) 2010 APA, all rights reserved)