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The aim of the study was to evaluate the applicability to urine samples of the Amplified Mycobacterium tuberculosis Direct Detection Test (AMTD), which is currently used to identify this organism in respiratory specimens within a few hours. The study was performed on 95 patients, comprising 35 subjects with a high index of suspicion for active tuberculosis of the urinary tract and 60 subjects with evidence of non-mycobacterial disease. One urine specimen from each subject was examined by microscopy, culture and AMTD. AMTD was positive in 38 specimens and negative in 57. Assuming culture as the reference standard, the sensitivity, specificity, positive predictive value and negative predictive value of AMTD were 100%, 91.93%, 86.84% and 100%, respectively. Reassessing the discrepancies between AMTD and culture by review of patients' charts, the sensitivity, specificity, positive predictive value and negative predictive value of AMTD were 100%, 93.44%, 89.47% and 100%. The results of the study as well as the characteristics of AMTD encourage its use for the rapid recognition of urinary tract tuberculosis, although its findings should be interpreted cautiously when the clinical picture is not consistent with an active tuberculosis.  相似文献   

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Examined 48 black and 48 white children, matched for social class and nonverbal intelligence, in a free-recall situation on vocabulary words and sentences presented in black dialect and standard English. On standard English sentences, both groups performed equally well. On sentences in black dialect, the white Ss performed significantly worse. Findings are interpreted as support for bilingual language development in black ghetto children and emphasize the importance of social class and intelligence when comparing black and white Ss on language tasks. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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A group of experts from gastroenterology, internal medicine, health economics, medical outcomes, and managed care met in San Francisco, Calif, on September 27, 1994, in an effort to develop clinically and economically effective disease management guidelines to assist physicians in their treatment of gastroesophageal reflux disease in a managed care environment. This article represents a consensus opinion based on the evidence and expert interpretation at the time of that meeting.  相似文献   

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Rumors have been flying that the Joint Commission is going to eliminate the requirement for a single nurse executive as required by standard NR. 1 in the Comprehensive Accreditation Manual for Hospitals (CAMH). This column clarifies the JCAHO's intent in this regard.  相似文献   

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This paper reports changes in adrenocorticotrophic hormone (ACTH), insulin and insulin-like growth factor-1 (IGF-1) concentrations in cats from a previously published study. The cats were given oral megestrol acetate (MA, 5 mg once daily for 14 days), subcutaneous proligestone (PRG, 100 mg on two occasions one week apart) or subcutaneous saline (1 ml as for PRG). In the cats given saline (n = 6), basal ACTH, insulin and IGF-1 did not change significantly throughout the following seven weeks. The cats given MA (n = 7) developed significant suppression of plasma ACTH concentrations and hyperinsulinaemia during treatment and for two to four weeks after MA dosage ceased. In the cats given PRG (n = 7), plasma ACTH concentrations were not significantly altered although three cats had markedly suppressed values for some time after PRG treatment had ceased. Serum insulin concentrations were not significantly altered in the PRG-treated cats. The results suggest PRG may be a preferable alternative to MA in some situations.  相似文献   

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The sudden loss of consciousness in a child is concerning to both patients and their parents. Although most cases of syncope in children are benign, an adequate evaluation is required to exclude life-threatening disorders. Patient history and physical examination may be sufficient to define the cause of syncope in a large percentage of pediatric cases. The events and setting preceding the syncopal episode provide clues in defining the nature of the event.  相似文献   

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In an experiment designed to elicit restrictive relatives clauses, 28 children ranging in age from 2; 2 to 3; 10 provided a corpus of communicatively appropriate relative clauses. In evaluating this corpus, we found that most children produced mostly adult relative clauses most of the time. Detailed study of these utterances uncovered a few error patterns, which we analyzed in light of several considerations (e.g. the overall frequency of an error type, its distribution across children and items, its relation to the construction under study, and the similarity of the error to what children do elsewhere). Only one error pattern, namely some children's production of inappropriate relative pronouns, is argued to reflect a systematic feature of language development. We conclude that children's ability to represent the syntactic structure of the embedded clause is on target very early.  相似文献   

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Lymphadenopathy is a common problem in children and adolescents. A detailed history and physical examination in addition to knowledge of lymph node anatomy is often adequate for diagnosis. The infectious and noninfectious causes of adenopathy are outlined according to location. Medical and surgical evaluation and treatment are discussed, with special attention given to mycobacterial infections, cat scratch disease, and lymphoma.  相似文献   

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OBJECTIVES: The purpose of this study was to determine whether persons with developmental dyspraxia and apraxia make similar errors during the performance of four types of tasks. METHOD: Three groups of subjects with dyspraxia or apraxia (i.e., children with learning disabilities and dyspraxia, young adults with learning disabilities and dyspraxia, older adults with left-hemisphere brain damage with apraxia) and three groups of age-matched control subjects (i.e., children, young adults, older adults) were observed performing transitive, intransitive, verbal command, and imitation tasks. Performance was scored on the basis of the types of errors made. Errors were classified as conceptual (nonrelated, unrecognizable, sequencing) or production (omission, perseveration, related, internal configuration, external configuration, incorrect movement, body part as object). RESULTS: No significant difference was found between conceptual and production error patterns for any group. In addition, there was no significant difference between the dyspraxia and apraxia groups or among the control groups on the specific types of production errors made. However, the dyspraxia and apraxia groups differed in the type of conceptual error made on the intransitive task. The body-part-as-object error was the most frequently made error on the transitive, verbal command, and imitation tasks, whereas the movement error was the most frequently made error on the intransitive task. CONCLUSION: Subjects with dyspraxia or apraxia make similar errors, suggesting that the praxis behaviors are similar.  相似文献   

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HIV in children     
Because children acquire HIV infection differently than adults, this article begins with a discussion of the epidemiology of AIDS in children. This is followed by a discussion of factors related to progression of the disease and survival in pediatric AIDS. A discussion of the pulmonary manifestations in children is followed by a suggested approach to the HIV-infected child with respiratory symptoms.  相似文献   

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Newly registered active tuberculosis in children is under 300 persons a year in Japan, now. In order to lessen further and exterminate childhood tuberculosis in near future, physician have to make effort to find the infected children by good-timing thorough surveillance when he find an adult tuberculosis patient. Chemoprophylaxis could prevent the infected children from progressing to active disease. BCG vaccination in infantile period is still important in Japan, especially to protect young children from disseminated tuberculosis. Pulmonary tuberculosis in children is successfully treated with 6 months standard multi-drugs therapy.  相似文献   

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In this article the last 30 years of research concerning headaches in children, especially migraine headaches, is reviewed. The article is directed towards epidemiology, identification, classification, pathophysiology and management. Headache is a common medical complaint in children and adolescents, but diagnosis can be difficult, particularly in the very young. Many know far too little about how to recognise a child with headache and how to deal with it.  相似文献   

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