Microencapsulation of a Natural Antioxidant from Coffee—Chlorogenic Acid (3-Caffeoylquinic Acid)

Chlorogenic acids, the main polyphenolic group present in coffee, which include the caffeoylquinic acids, are recognized as antioxidants with growing interest in pharmacological, cosmetic, and food applications. However, they can be easily oxidized and they are also very unstable when exposed to high temperatures. Therefore, they can suffer transesterification reactions during storage or food processing, limiting their applications. Nevertheless, this situation can be overcome or minimized by microencapsulation. The purpose of the present study was to prepare by a spray-drying process sodium alginate and modified chitosan microparticles with chlorogenic acid (3-CQA), characterize them (morphological analysis), and evaluate the release profile of 3-CQA from the microparticles in in vitro studies. Furthermore, their antioxidant activity and moisture content were determined. The results address the success of chlorogenic acid microencapsulation, resulting in stable microparticles with controlled release properties and good antioxidant activity, suggesting increasing applications in food and pharmaceutical industry.     

Microencapsulation as a tool for incorporating bioactive ingredients into food

Microencapsulation has been developed by the pharmaceutical industry as a means to control or modify the release of drug substances from drug delivery systems. In drug delivery systems microencapsulation is used to improve the bioavailability of drugs, control drug release kinetics, minimize drug side effects, and mask the bitter taste of drug substances. The application of microencapsulation has been extended to the food industry, typically for controlling the release of flavorings and the production of foods containing functional ingredients (e.g. probiotics and bioactive ingredients). Compared to the pharmaceutical industry, the food industry has lower profit margins and therefore the criteria in selecting a suitable microencapsulation technology are more stringent. The type of microcapsule (reservoir and matrix systems) produced and its resultant release properties are dependent on the microencapsulation technology, in addition to the physicochemical properties of the core and the shell materials. This review discusses the factors that affect the release of bioactive ingredients from microcapsules produced by different microencapsulation technologies. The key criteria in selecting a suitable microencapsulation technology are also discussed. Two of the most common physical microencapsulation technologies used in pharmaceutical processing, fluidized-bed coating, and extrusion-spheronization are explained to highlight how they might be adapted to the microencapsulation of functional bioactive ingredients in the food industry.     

Microencapsulation of active ingredients in functional foods: From research stage to commercial food products

BackgroundTwelves categories of active ingredients have been recognised to enhance human health. They are to some extent susceptible to certain conditions such as heat, light and low pH. To reduce their susceptibility and achieve controlled release at the target site, various microencapsulation strategies have been introduced.Scope and approachIn this review, the chemical structures, physicochemical properties and beneficial effects of the active components are summarised. Different encapsulation techniques and tailored shell materials have been investigated to optimise the functional properties of microcapsules. Several encapsulated constituents (e.g., amino acids) have been successfully incorporated into food products while others such as lactic acid bacteria are mostly used in the free format. Encapsulating some of these active ingredients will extend their ability to withstand process conditions such as heat and shear, and prolong their shelf stability.Key findings and conclusionsThe functional properties of a microcapsule are encapsulation efficiency, size, morphology, stability, and release characteristics. Several microencapsulation strategies include the use of double emulsions, hybrid wall materials and crosslinkers, increasing intermolecular attraction between shell and core, physical shielding of shell materials, and the addition of certain ions. Other approaches such as the use of hardening agents, nanoencapsulation, or secondary core materials, and the choice of shell materials possessing specific interactions with the core may be used to achieve targeted release of active ingredients. The physicochemical properties of shell materials influence where the active ingredients will be released in vivo. A suitable microencapsulation strategy of active ingredients will therefore expand their applications in the functional foods industry.     

Microencapsulation: industrial appraisal of existing technologies and trends

Controlled release of food ingredients at the right place and the right time is a key functionality that can be provided by microencapsulation. A timely and targeted release improves the effectiveness of food additives, broadens the application range of food ingredients and ensures optimal dosage, thereby improving cost-effectiveness for the food manufacturer. Reactive, sensitive or volatile additives (vitamins, cultures, flavors, etc.) can be turned into stable ingredients through microencapsulation. With carefully fine-tuned controlled release properties, microencapsulation is no longer just an added value technique, but the source of totally new ingredients with matchless properties.     

Application of starch microcapsules containing essential oil in food preservation

Abstract

Consumers' pursuit to a healthy lifestyle has promoted people to develop new technologies that can prolong the shelf life of food without the use of preservatives. Compared with other types of preservation, edible microcapsules containing essential oils (EOs) are becoming more and more popular especially the starch microcapsules containing essential oil (EOs-starch microcapsules) because of their environmentally friendly, healthier characteristics and the ability to carry active ingredients. In addition, the EOs-starch microcapsules can also reduce the flavor influence and prolong the action time of essential oil on food through its slow release effect, which can promote the use of EOs in food. Understanding the different collocation of edible starch microcapsules and EOs and the related antibacterial mechanism will be more effective and targeted to promote the application of EOs in the real food system. The review focus on the contribution of EOs-starch microcapsules to prolong the shelf life of food products, (1) binding characteristics of EOs-starch microcapsules were analyzed, (2) systematically summarizing the main materials and methods for preparing the EOs-microcapsules, (3) specifically addressing the action mechanisms of EOs-starch microcapsules on microorganism, (4) discussing the applications of EOs-starch microcapsules in specific food.     

微胶囊技术及其在食品加工中的应用

微胶囊技术是目前研究开发的高新技术之一,利用微胶囊化方法不仅叮增加产品的附加值,更足获得优良性新原料的良好来源。文中概述了常用的微胶囊化的方法,并从工艺特点、适用概况和独特性能上进行比较,简述了其在食品加工中的应用。     

Application of edible coating with essential oil in food preservation

Abstract

Compared with other types of packaging, edible coatings are becoming more and more popular because of their more environmentally friendly properties and active ingredients carrying ability.

The edible coating can reduce the influence of essential oils (EOs) on the flavor of the product and also can prolong the action time of EOs through the slow-release effect, which effectively promote the application of EOs in food. Understanding the different combinations of edible coatings and EOs as well as their antimicrobial effects on different microorganisms will be more powerful and targeted to promote the application of EOs in real food systems.

The review focus on the contribution of the combination of EOs and edible coatings (EO-edible coatings) to prolong the shelf life of food products, (1) specifically addressing the main materials used in the preparation of EO-edible coatings and the application of EO-edible coatings in the product, (2) systematically summarizing the main production method of EO-edible coatings, (3) discussing the antiseptic activity of EO-edible coatings on different microorganisms in food.     

The function of polyglyceryl erucate/isostearate/ricinoleate

Today, it is said that the formula design of cosmetics from ingredients of plant origin is an indispensable way and trend. From this consideration, cosmetic materials made from animal and synthetic petroleum ingredients are becoming less usable. Instead, cosmetic materials are designed from ingredients of plant origin and many and various botanical ingredients are being developed. Lanolin, which is one of the animal-based ingredients, is said to have ideal functions as a cosmetic oil, and it has been used in many fields such as make-up cosmetics as well as hair and skin care products for a long time. However, unfortunately, lanolin is an animal-based ingredient; therefore, the development of a botanical ingredient to replace lanolin was desired. Polyglyceryl-8 decaerucate/isostearate/ricinoleate, which we have developed, is an ester oil originating from plants and has an equivalent or higher function than lanolin. We have confirmed that our developed ester oil has various excellent characteristics such as a water-holding capability 2.5 times higher than that of lanolin, high air permeability, moisture keeping in dermal layers, protection of hair from changes in external environmental humidity, and excellent gloss and excellent dispersability of pigments. Thus, this newly developed ester oil is expected to be a promising new botanical cosmetic ingredient which can be applied in various fields.     

微胶囊技术的新进展

微胶囊技术是21世纪重点研究开发的高新技术之一,用途广泛,其不仅仅增加产品的附加值,更是获得具有优良特性新原料的良好来源。本文概述了食品工业中常用的微胶囊化方法的新进展、双层微胶囊理论以及微胶囊技术在食品工业中的广泛应用,最后总结了其发展前景。     

Antimicrobial activity of whey protein isolate edible films with essential oils against food spoilers and foodborne pathogens

The use of antimicrobial edible film is proposed as a means of improving food safety and extending the shelf-life of food systems by controlling the release of antimicrobials on food surfaces. In this work we first selected and studied 8 different essential oils (EOs) from plants, namely, oregano, clove, tea tree, coriander, mastic thyme, laurel, rosemary, and sage as natural antimicrobials against 2 gram-positive bacteria (Listeria innocua and Staphylococcus aureus) and 2 gram-negative bacteria (Salmonella enteritidis and Pseudomona fragi) by using the agar disk diffusion method. EOs from oregano, clove, and tea tree produced the largest surfaces of inhibition against the growth of the 4 bacterial strains tested. Second and following the assessment of compatibility, stable antimicrobial edible films based on whey protein isolate (WPI) with increasing concentrations (0.5% to 9%) of the 8 EOs were developed and tested for antimicrobial activity against the same gram-positive and gram-negative bacteria. WPI-edible films incorporating oregano or clove EO were found to have the most intense inhibitory effect of microbial growth. The bacterial strain gram-negative P. fragi presented the less susceptibility to the effect of those films. Moreover, only the edible films based on these 2 EOs were active against all 4 studied microorganisms. On the other hand, the edible films incorporating tea tree, coriander, mastic thyme, laurel, rosemary, or sage EOs even at high concentrations (7% to 9%) did not cause any antimicrobial effect against the pathogens S. aureus or S. enteritidis. PRACTICAL APPLICATION: Potential applications of this technology can introduce direct benefits to the food industry by improving safety and microbial product quality. The results of this research have direct application in the food industry with potential applications in various foodstuffs, including meat and poultry products where the control of spoilage bacteria such as P. fragi throughout their chilled storage or the improvement of food safety by controlling pathogens such as S. enteritidis are topics of particular interest for the industry.     

天然可食性壁材虫胶在功能组分微囊化中的应用研究进展

虫胶是一种新兴的功能性组分微囊化壁材,天然、无毒、生物可降解,具有在中酸性水溶液中不溶、碱性水溶液中溶解的特性,以及良好的成膜性和热性能,可较好地应用于耐酸、阻湿、胃肠道控释等方面。本文综述了虫胶的组成、物化特性;以食品、制药行业中的益生菌、维生素、天然色素、油脂、蛋白、药物等组分为代表,归纳总结了虫胶微囊化在各产业中的应用研究进展;以挤压法、乳化法、相分离法、电喷雾法和静电纺丝法为代表,详细介绍了虫胶的微囊化方法;并对虫胶及其微囊化的研究方向进行展望。     

Renewable sources: applications in personal care formulations

A global tendency for products considered environmentally sustainable, and ecologically obtained led the industry related to personal care formulations to fund the research and the development of personal care/cosmetics containing ingredients from natural resources. Furthermore, consumers are aware of environmental and sustainability issueans, thus not harming the environment represents a key consideration when developing a new cosmetic ingredient. In this study we review some examples of active ingredients or raw materials used in cosmetics/personal care/biomedical products that are coming from either through biotechnological systems, or as byproducts of several industries. A skin formulation containing biosynthetic actives, prepared by us and the study regarding its dermocosmetic properties are also described. The need for the standardization processes, the safety assessment tools, the improvement of the exploitation methods of these renewable sources in order the production to be ecologically and economically better are also discussed.     

食品添加剂行业将成为我国食品工业新的增长点

食品添加剂、食品配料是焕发食品特色的主要元素,随着消费者对新颖独特食品的不断需求,开发新型功能的食品添加剂已是大势所趋。1998年,我国食品添加剂总产值约占国际贸易额的10％;出口创汇达4.7亿美元,比1997年增长12％。 我国食品工业的总产值虽已跃居各工业部门的第一位,但其发展仍落后于农产品加工发展的需要。以产值计算,食品工业仅占农产品产值的50％左右;加上食品工业的结构不合理,初级加工产值占食品加工工业总值的一半。为此,我国应大力发展食品工业的深加工,开发新的产品,换句话说,今后要继续按照我国食品工业的发展重点,大力开发能进入一日三餐的方便营养食品和满足不同人群需要的特种营养食品,遵循食品添加剂天然、营养、多功能的发展方针,可以预见,我国食品添加剂工业的发展前景乐观而广阔。     

食品智能控释技术及其在益生菌制品的应用

食品智能控释技术是指食品的功能属性成分通过对其在食品加工以及摄取过程的环境响应来控制功能属性成分的释放与否、释放速度以及释放程度.智能控释有利于食品成分在食品加工、储藏过程的稳定,也能使其充分赋予食品的功能属性.可应用于食品的智能控释技术包括微胶囊化技术、微球技术、纳米技术、脂质体技术、超分子形成法等.在益生菌制品中应用智能控释技术,可以提高益生菌加工和储藏过程的耐热、耐氧性能,摄入体内能耐受胃酸而不产生释放,确保最多的活菌到达肠道产生释放,从而发挥益生菌的最大功能活性。     

Application of artificial neural networks to the prediction of the antioxidant activity of essential oils in two experimental in vitro models

Introduction

The antioxidant properties of essential oils (EOs) have been on the centre of intensive research for their potential use as preservatives or nutraceuticals by the food industry. The enormous amount of information already generated on this subject provides a rich field for data-miners as it is conceivable, with suitable computational techniques, to predict the antioxidant capacity of any essential oil just by knowing its particular chemical composition. To accomplish this task we here report on the design, training and validation of an Artificial Neural Network (ANN) able to predict the antioxidant activity of EOs of known chemical composition.

Methods

A multilayer ANN with 30 input neurons, 42 in hidden layers (20 → 15 → 7) and one neuron in the output layer was developed and run using Fast Artificial Neural Network software. The chemical composition of 32 EOs and their antioxidant activity in the DPPH and linoleic acid models were extracted from the scientific literature and used as input values. From the initial set of around 80 compounds present in these EOs, only 30 compounds with relevant antioxidant capacity were selected to avoid excessive complexity of the neural network and minimise the associated structural problems.

Results and discussion

The ANN could predict the antioxidant capacities of essential oils of known chemical composition in both the DPPH and linoleic acid assays with an average error of only 3.16% and 1.46%, respectively. We also discuss on the contribution of different compounds to these chemical activities.

Conclusions

These results confirm that artificial neural networks are reliable, fast and cheap tools for predicting antioxidant activity of essential oils from some of its components and can be used to model biochemical properties of complex natural products including the prediction of parameters associated with nutraceutical properties of food ingredients.     

Review Article: Oral malodour and active ingredients for treatment

Oral care preparations are widely used for the treatment of oral malodour as over‐the‐counter products. Bad breath is highly distressing to an individual’s confidence during social interaction, which is a large concern nowadays as the consumption of these products is increasing worldwide. However, oral deodorant ingredients are rarely studied compared with other cosmetic ingredients, and the only preparations which are well known are those contained in dentifrices and mouthrinses. This review briefly summarizes the compounds which cause oral malodour and the treatments available. The active ingredients in various preparations are emphasized and novel products are presented.     

Encapsulation of Fish Oil by an Enzymatic Gelation Process Using Transglutaminase Cross-linked Proteins

ABSTRACT To improve the storage stability and achieve controlled release, fish oil containing docosahexaenoic acid was encapsulated using double emulsification and subsequent enzymatic gelation method, using microbial transglutaminase cross-linked proteins. Isolated soy protein was selected as a wall material because it showed better emulsion stability and higher reactivity with MTGase than other proteins. Microcapsules prepared by this method showed a high stability against oxygen and a low water solubility, which subsequently resulted in sustained release of fish oil. Results indicate that this microencapsulation process is suitable for preparing protein-based microcapsules containing sensitive ingredients for controlled release and stability improvement.     

Flavonoid microparticles by spray-drying: Influence of enhancers of the dissolution rate on properties and stability

Naringenin (Nn) and Quercetin (Q) have numerous health benefits particularly due to their antioxidant properties. However, their low solubility, bioavailability and stability limit their use as components for functional foods, nutraceuticals and pharmaceutical agents. In this research, Nn- and Q-microparticles were produced by a spray-drying process using a combination of cellulose acetate phthalate (CAP) as coating gastroresistant polymer and swelling or surfactant agents as enhancers of dissolution rate. Raw materials and microparticles produced were all characterized by particle size analysis, differential scanning calorimetry, X-ray diffraction, and imaged by electron and fluorescence microscopy. During 12 months, storage stability was evaluated by analyzing drug content, HPLC and DSC profiles, as well as antioxidant activity (DPPH test). In vitro dissolution tests, using a pH-change method, were carried out to investigate the influence of formulative parameters on flavonoid release from the microparticles. Presence of a combination of CAP and surfactants or swelling agents in the formulations produced microparticles with good resistance at low pH of the gastric fluid and complete flavonoid release in the intestinal environment. The spray-drying technique and the process conditions selected have given satisfying encapsulation efficiency and product yield. The microencapsulation have improved the technological characteristics of the powders such as morphology and size, have given long-lasting storage stability and have preserved the antioxidant properties.     

Citrus essential oils: Extraction,authentication and application in food preservation

Citrus EOs is an economic, eco-friendly and natural alternatives to chemical preservatives and other synthetic antioxidants, such as sodium nitrites, nitrates or benzoates, commonly utilized in food preservation. Citrus based EOs is obtained mainly from the peels of citrus fruits which are largely discarded as wastes and cause environmental problems. The extraction of citrus oils from the waste peels not only saves environment but can be used in various applications including food preservation. The present article presents elaborated viewpoints on the nature and chemical composition of different EOs present in main citrus varieties widely grown across the globe; extraction, characterization and authentication techniques/methods of the citrus EOs; and reviews the recent advances in the application of citrus EOs for the preservation of fruits, vegetables, meat, fish and processed food stuffs. The probable reaction mechanism of the EOs based thin films formation with biodegradable polymers is presented. Other formulation, viz., EOs microencapsulation incorporating biodegradable polymers, nanoemulsion coatings, spray applications and antibacterial action mechanism of the active compounds present in the EOs have been elaborated. Extensive research is required on overcoming the challenges regarding allergies and obtaining safer dosage limits. Shift towards greener technologies indicate optimistic future towards safer utilization of citrus based EOs in food preservation.     

Neue Konzepte der Reststoffverwertung in der Lebensmittelindustrie - Chancen für die Kartoffelstärkeindustrie

New concepts for the utilisation of residual products from food industry - Prospects for the potato starch industry. In disposed waste are quite a lot of reusable substances of high value. These residual products can be transferred into commercial products in dependency to the adequate technology either as raw material for secondary processes, as operating supplies or as ingredients of novel products. Numerous valuable substances in food production are suitable for separation and recycling at the end of their life cycle even though present separation and recycling processes are not absolutely cost saving. Based on a concept of food production in its entirely the actual state is exemplary demonstrated at the potato starch industry in its occurrence, quantity and utilisation of the residual products. The target state of a clean production process will be realised by the development of multifunctional food ingredients. The outlined concept can be naturally transferred to several areas of industrial food production. The intentions of this research area are located at the development of techniques, which fulfil the conditions of environmental protection with costs to a minimum.