Epileptic Seizures Diagnosis Using Amalgamated Extremely Focused EEG Signals and Brain MRI

There exists various neurological disorder based diseases like tumor, sleep disorder, headache, dementia and Epilepsy. Among these, epilepsy is the most common neurological illness in humans, comparable to stroke. Epilepsy is a severe chronic neurological illness that can be discovered through analysis of the signals generated by brain neurons and brain Magnetic resonance imaging (MRI). Neurons are intricately coupled in order to communicate and generate signals from human organs. Due to the complex nature of electroencephalogram (EEG) signals and MRI’s the epileptic seizures detection and brain related problems diagnosis becomes a challenging task. Computer based techniques and machine learning models are continuously giving their contributions to diagnose all such diseases in a better way than the normal process of diagnosis. Their performance may sometime degrade due to missing information, selection of poor classification model and unavailability of quality data that are used to train the models for better prediction. This research work is an attempt to epileptic seizures detection by using a multi focus dataset based on EEG signals and brain MRI. The key steps of this work are: feature extraction having two different streams i.e., EEG using wavelet transformation along with SVD-Entropy, and MRI using convolutional neural network (CNN), after extracting features from both streams, feature fusion is applied to generate feature vector used by support vector machine (SVM) to diagnose the epileptic seizures. From the experimental evaluation and results comparison with the current state-of-the-art techniques, it has been concluded that the performance of the proposed scheme is better than the existing models.

     

Evolutionary Algorithsm with Machine Learning Based Epileptic Seizure Detection Model

Machine learning (ML) becomes a familiar topic among decision makers in several domains, particularly healthcare. Effective design of ML models assists to detect and classify the occurrence of diseases using healthcare data. Besides, the parameter tuning of the ML models is also essential to accomplish effective classification results. This article develops a novel red colobuses monkey optimization with kernel extreme learning machine (RCMO-KELM) technique for epileptic seizure detection and classification. The proposed RCMO-KELM technique initially extracts the chaotic, time, and frequency domain features in the actual EEG signals. In addition, the min-max normalization approach is employed for the pre-processing of the EEG signals. Moreover, KELM model is used for the detection and classification of epileptic seizures utilizing EEG signal. Furthermore, the RCMO technique was utilized for the optimal parameter tuning of the KELM technique in such a way that the overall detection outcomes can be considerably enhanced. The experimental result analysis of the RCMO-KELM technique has been examined using benchmark dataset and the results are inspected under several aspects. The comparative result analysis reported the better outcomes of the RCMO-KELM technique over the recent approaches with the of 0.956.     

Deep Learning and Machine Learning for Early Detection of Stroke and Haemorrhage

Stroke and cerebral haemorrhage are the second leading causes of death in the world after ischaemic heart disease. In this work, a dataset containing medical, physiological and environmental tests for stroke was used to evaluate the efficacy of machine learning, deep learning and a hybrid technique between deep learning and machine learning on the Magnetic Resonance Imaging (MRI) dataset for cerebral haemorrhage. In the first dataset (medical records), two features, namely, diabetes and obesity, were created on the basis of the values of the corresponding features. The t-Distributed Stochastic Neighbour Embedding algorithm was applied to represent the high-dimensional dataset in a low-dimensional data space. Meanwhile,the Recursive Feature Elimination algorithm (RFE) was applied to rank the features according to priority and their correlation to the target feature and to remove the unimportant features. The features are fed into the various classification algorithms, namely, Support Vector Machine (SVM), K Nearest Neighbours (KNN), Decision Tree, Random Forest, and Multilayer Perceptron. All algorithms achieved superior results. The Random Forest algorithm achieved the best performance amongst the algorithms; it reached an overall accuracy of 99%. This algorithm classified stroke cases with Precision, Recall and F1 score of 98%, 100% and 99%, respectively. In the second dataset, the MRI image dataset was evaluated by using the AlexNet model and AlexNet + SVM hybrid technique. The hybrid model AlexNet + SVM performed is better than the AlexNet model; it reached accuracy, sensitivity, specificity and Area Under the Curve (AUC) of 99.9%, 100%, 99.80% and 99.86%, respectively.     

Classification of Electroencephalogram Signals Using LSTM and SVM Based on Fast Walsh-Hadamard Transform

Classification of electroencephalogram (EEG) signals for humans can be achieved via artificial intelligence (AI) techniques. Especially, the EEG signals associated with seizure epilepsy can be detected to distinguish between epileptic and non-epileptic regions. From this perspective, an automated AI technique with a digital processing method can be used to improve these signals. This paper proposes two classifiers: long short-term memory (LSTM) and support vector machine (SVM) for the classification of seizure and non-seizure EEG signals. These classifiers are applied to a public dataset, namely the University of Bonn, which consists of 2 classes –seizure and non-seizure. In addition, a fast Walsh-Hadamard Transform (FWHT) technique is implemented to analyze the EEG signals within the recurrence space of the brain. Thus, Hadamard coefficients of the EEG signals are obtained via the FWHT. Moreover, the FWHT is contributed to generate an efficient derivation of seizure EEG recordings from non-seizure EEG recordings. Also, a k-fold cross-validation technique is applied to validate the performance of the proposed classifiers. The LSTM classifier provides the best performance, with a testing accuracy of 99.00%. The training and testing loss rates for the LSTM are 0.0029 and 0.0602, respectively, while the weighted average precision, recall, and F1-score for the LSTM are 99.00%. The results of the SVM classifier in terms of accuracy, sensitivity, and specificity reached 91%, 93.52%, and 91.3%, respectively. The computational time consumed for the training of the LSTM and SVM is 2000 and 2500 s, respectively. The results show that the LSTM classifier provides better performance than SVM in the classification of EEG signals. Eventually, the proposed classifiers provide high classification accuracy compared to previously published classifiers.     

Performance Evaluation of Deep Dense Layer Neural Network for Diabetes Prediction

Diabetes is one of the fastest-growing human diseases worldwide and poses a significant threat to the population’s longer lives. Early prediction of diabetes is crucial to taking precautionary steps to avoid or delay its onset. In this study, we proposed a Deep Dense Layer Neural Network (DDLNN) for diabetes prediction using a dataset with 768 instances and nine variables. We also applied a combination of classical machine learning (ML) algorithms and ensemble learning algorithms for the effective prediction of the disease. The classical ML algorithms used were Support Vector Machine (SVM), Logistic Regression (LR), Decision Tree (DT), K-Nearest Neighbor (KNN), and Naïve Bayes (NB). We also constructed ensemble models such as bagging (Random Forest) and boosting like AdaBoost and Extreme Gradient Boosting (XGBoost) to evaluate the performance of prediction models. The proposed DDLNN model and ensemble learning models were trained and tested using hyperparameter tuning and K-Fold cross-validation to determine the best parameters for predicting the disease. The combined ML models used majority voting to select the best outcomes among the models. The efficacy of the proposed and other models was evaluated for effective diabetes prediction. The investigation concluded that the proposed model, after hyperparameter tuning, outperformed other learning models with an accuracy of 84.42%, a precision of 85.12%, a recall rate of 65.40%, and a specificity of 94.11%.     

Machine Learning Approach for COVID-19 Detection on Twitter

Social networking services (SNSs) provide massive data that can be a very influential source of information during pandemic outbreaks. This study shows that social media analysis can be used as a crisis detector (e.g., understanding the sentiment of social media users regarding various pandemic outbreaks). The novel Coronavirus Disease-19 (COVID-19), commonly known as coronavirus, has affected everyone worldwide in 2020. Streaming Twitter data have revealed the status of the COVID-19 outbreak in the most affected regions. This study focuses on identifying COVID-19 patients using tweets without requiring medical records to find the COVID-19 pandemic in Twitter messages (tweets). For this purpose, we propose herein an intelligent model using traditional machine learning-based approaches, such as support vector machine (SVM), logistic regression (LR), naïve Bayes (NB), random forest (RF), and decision tree (DT) with the help of the term frequency inverse document frequency (TF-IDF) to detect the COVID-19 pandemic in Twitter messages. The proposed intelligent traditional machine learning-based model classifies Twitter messages into four categories, namely, confirmed deaths, recovered, and suspected. For the experimental analysis, the tweet data on the COVID-19 pandemic are analyzed to evaluate the results of traditional machine learning approaches. A benchmark dataset for COVID-19 on Twitter messages is developed and can be used for future research studies. The experiments show that the results of the proposed approach are promising in detecting the COVID-19 pandemic in Twitter messages with overall accuracy, precision, recall, and F1 score between 70% and 80% and the confusion matrix for machine learning approaches (i.e., SVM, NB, LR, RF, and DT) with the TF-IDF feature extraction technique.     

A novel two-band equilateral wavelet filter bank method for an automated detection of seizure from EEG signals

One can determinate the occurrence of epileptic seizure from the electroencephalogram (EEG) signal. Nonautomatic epilepsy detection is onerous and may be prone to error. They have augmented automated detection of seizure methods to attain accurate results. In view of this research work, we designed a frequency localized optimal filter bank to assess their effectiveness for automatic detection of seizures from EEG records. The basic preferred requirement of optimal filters relies on low bandwidth in the discipline of biomedical signal processing. This work provides a novel filter bank method called optimal equilateral wavelet filter bank (OEWFB) to satisfy the regularity criteria. This regularity constraint is being satisfied with semi-definite programming (SDP) framework, which specifically does nothing with any parameterization. Implementing the proposed filter banks, it disbands EEG signals into five wavelet sub-bands. The fuzzy entropy (FuEn), Renyi's entropy (ReEn), and the Kraskov entropy (KrEn) are being used for extracting the features from the wavelet sub-bands. The P values provide the distinctive ability of the features. Classification with 10-fold cross-validation for several classifiers such as quadratic discriminant, linear quadratic discriminant, K-nearest neighbor, support vector machine, logistic regression, and complex tree is utilized to classify the EEG signals into seizure vs non-seizure class and seizure-free vs seizure affected class. The proposed research work has gained the highest accuracy, specificity, sensitivity, and positive predictive values of 99.4%, 99%, 99.66%, and 99.35%, respectively, for class-1 (ABCD vs E). The performances of the proposed work using the Bonn EEG data set ensure validation concerning compatibility and robustness.     

Multi-View & Transfer Learning for Epilepsy Recognition Based on EEG Signals

Epilepsy is a central nervous system disorder in which brain activity becomes abnormal. Electroencephalogram (EEG) signals, as recordings of brain activity, have been widely used for epilepsy recognition. To study epileptic EEG signals and develop artificial intelligence (AI)-assist recognition, a multi-view transfer learning (MVTL-LSR) algorithm based on least squares regression is proposed in this study. Compared with most existing multi-view transfer learning algorithms, MVTL-LSR has two merits: (1) Since traditional transfer learning algorithms leverage knowledge from different sources, which poses a significant risk to data privacy. Therefore, we develop a knowledge transfer mechanism that can protect the security of source domain data while guaranteeing performance. (2) When utilizing multi-view data, we embed view weighting and manifold regularization into the transfer framework to measure the views’ strengths and weaknesses and improve generalization ability. In the experimental studies, 12 different simulated multi-view & transfer scenarios are constructed from epileptic EEG signals licensed and provided by the University of Bonn, Germany. Extensive experimental results show that MVTL-LSR outperforms baselines. The source code will be available on .     

Classification of focal and nonfocal EEG signals using ANFIS classifier for epilepsy detection

The electroencephalogram (EEG) is the frequently used signal to detect epileptic seizures in the brain. For a successful epilepsy surgery, it is very essential to localize epileptogenic area in the brain. The signals from the epileptogenic area are focal signals and signals from other area of the brain region nonfocal signals. Hence, the classification of focal and nonfocal signals is important for locating the epileptogenic area for epilepsy surgery. In this article, we present a computer aided automatic detection and classification method for focal and nonfocal EEG signal. The EEG signal is decomposed by Dual Tree Complex Wavelet Transform (DT‐CWT) and the features are computed from the decomposed coefficients. These features are trained and classified using Adaptive Neuro Fuzzy Inference System (ANFIS) classifier. The proposed system achieves 98% sensitivity, 100% specificity, and 99% accuracy for EEG signal classification. The experimental results are presented to show the effectiveness of the proposed classification method to classify the focal and nonfocal EEG signals. © 2016 Wiley Periodicals, Inc. Int J Imaging Syst Technol, 26, 277–283, 2016     

Imbalanced Classification in Diabetics Using Ensembled Machine Learning

Diabetics is one of the world’s most common diseases which are caused by continued high levels of blood sugar. The risk of diabetics can be lowered if the diabetic is found at the early stage. In recent days, several machine learning models were developed to predict the diabetic presence at an early stage. In this paper, we propose an embedded-based machine learning model that combines the split-vote method and instance duplication to leverage an imbalanced dataset called PIMA Indian to increase the prediction of diabetics. The proposed method uses both the concept of over-sampling and under-sampling along with model weighting to increase the performance of classification. Different measures such as Accuracy, Precision, Recall, and F1-Score are used to evaluate the model. The results we obtained using K-Nearest Neighbor (kNN), Naïve Bayes (NB), Support Vector Machines (SVM), Random Forest (RF), Logistic Regression (LR), and Decision Trees (DT) were 89.32%, 91.44%, 95.78%, 89.3%, 81.76%, and 80.38% respectively. The SVM model is more efficient than other models which are 21.38% more than exiting machine learning-based works.     

Epileptic seizure detection by combining robust‐principal component analysis and least square‐support vector machine

The feature extraction from electroencephalogram (EEG) signals is widely used for computer‐aided epileptic seizure detection. However, multiple channels of EEG signals and their correlations have not been completely harnessed. In this article, a novel automatic seizure detection approach is proposed by analyzing the spatiotemporal correlation of multi‐channel EEG signals. This approach combines the maximum cross‐correlation, robust‐principal component analysis, and least square‐support vector machine to detect the events. Our proposed method delivers higher detection sensitivity, specificity, and accuracy than the state‐of‐the‐art approaches based on the 19 channels’ EEG signals of 37 absence epilepsy patients experiencing 57 seizure events.     

Detection and classification of large bowel obstruction from X-ray images using machine learning algorithms

Large bowel obstruction (LBO) occurs when there is a blockage or twisting in the large bowel that prevents wastes and gas from passing through. If left untreated, the blockage cuts off blood supply to the colon, causing sections of it to die which results in high rates of morbidity and fatality. The examination of clinical symptoms of LBO involves careful inspection of the cecum and colon. Radiologists use X-rays to inspect the clinical signs. Some research has been done to automate the detection of related abdominal and intestinal diseases. However, all these studies concentrate only on detecting Crohn's, ulcerative colitis, Acute Appendicitis, colorectal cancer, celiac diseases, liver diseases, and chronic kidney diseases. Automatic detection and classification of LBO has not been given due attention so far to the best of the authors knowledge. To address this challenge, we have designed a model for the detection and classification of LBO. The models development comprises of stages such as preprocessing, detection, segmentation, feature extraction, and classification. We used YOLOv3 for detection and used a gray scale level co-occurrence matrix (GLCM), and a convolutional neural network for feature extraction, while support vector machine (SVM) and softmax were used for classification. The proposed model achieved a diagnostic accuracy of 89% when feature extraction methods such as CNN and median filter with softmax classifier were used. CNN and Gaussian filter with soft max classifier achieved 91%, while CNN and anisotropic filter with soft max classifier achieved 92%. GLCM with threshold segmentation and Gaussian filter with SVM classifier achieved 87%, while CNN with watershed segmentation and Gaussian filter with SVM classifier achieved 97% and CNN-GLCM with watershed segmentation and anisotropic diffusion filter with SVM classifier achieved 98% for detection and classification of LBO. Finally, this paper presented a performance analysis of various machine learning approaches for detection and classification of LBO. Hence, our model is designed to assist human experts (Radiologists) in diagnosing LBO.     

基于交叉验证SVM的网络入侵检测

针对传统入侵检测系统漏报率和误报率高的问题,将支持向量机(SVM)应用于入侵检测中,提出了在SVM学习过程中引入交叉验证的方法,采用径向基函数(RBF)作为核,将训练集分成若干子集,每一子集使用其它子集训练得到的分类器进行测试,获得RBF的两个最佳参数后,将其应用于最终的分类器.实验结果表明,该方法能够有效检测入侵攻击,具有更高的检测率和更强的泛化能力,同时具有较低的误报率和漏报率,可以有效地运用于入侵检测系统中.     

Electroencephalogram (EEG) Brain Signals to Detect Alcoholism Based on Deep Learning

The detection of alcoholism is of great importance due to its effects on individuals and society. Automatic alcoholism detection system (AADS) based on electroencephalogram (EEG) signals is effective, but the design of a robust AADS is a challenging problem. AADS’ current designs are based on conventional, hand-engineered methods and restricted performance. Driven by the excellent deep learning (DL) success in many recognition tasks, we implement an AAD system based on EEG signals using DL. A DL model requires huge number of learnable parameters and also needs a large dataset of EEG signals for training which is not easy to obtain for the AAD problem. In order to solve this problem, we propose a multi-channel Pyramidal neural convolutional (MP-CNN) network that requires a less number of learnable parameters. Using the deep CNN model, we build an AAD system to detect from EEG signal segments whether the subject is alcoholic or normal. We validate the robustness and effectiveness of proposed AADS using KDD, a benchmark dataset for alcoholism detection problem. In order to find the brain region that contributes significant role in AAD, we investigated the effects of selected 19 EEG channels (SC-19), those from the whole brain (ALL-61), and 05 brain regions, i.e., TEMP, OCCIP, CENT, FRONT, and PERI. The results show that SC-19 contributes significant role in AAD with the accuracy of 100%. The comparison reveals that the state-of-the-art systems are outperformed by the AADS. The proposed AADS will be useful in medical diagnosis research and health care systems.     

Spatial analysis of intracerebral electroencephalographic signals in the time and frequency domain: identification of epileptogenic networks in partial epilepsy

Electroencephalography (EEG) occupies an important place for studying human brain activity in general, and epileptic processes in particular, with appropriate time resolution. Scalp EEG or intracerebral EEG signals recorded in patients with drug-resistant partial epilepsy convey important information about epileptogenic networks that must be localized and understood prior to subsequent therapeutic procedures. However, this information, often subtle, is 'hidden' in the signals. It is precisely the role of signal processing to extract this information and to put it into a 'coherent and interpretable picture' that can participate in the therapeutic strategy. Nowadays, the panel of available methods is very wide depending on the objectives such as, for instance, the detection of transient epileptiform events, the detection and/or prediction of seizures, the recognition and/or the classification of EEG patterns, the localization of epileptic neuronal sources, the characterization of neural synchrony, the determination of functional connectivity, among others. The intent of this paper is to focus on a specific category of methods providing relevant information about epileptogenic networks from the analysis of spatial properties of EEG signals in the time and frequency domain. These methods apply to either interictal or ictal recordings and share the common objective of localizing the subsets of brain structures involved in both types of paroxysmal activity. Most of these methods were developed by our group and are routinely used during pre-surgical evaluation. Examples are detailed. Results, as well as limitations of the methods, are also discussed.     

M-IDM: A Multi-Classification Based Intrusion Detection Model in Healthcare IoT

In recent years, the application of a smart city in the healthcare sector via loT systems has continued to grow exponentially and various advanced network intrusions have emerged since these loT devices are being connected. Previous studies focused on security threat detection and blocking technologies that rely on testbed data obtained from a single medical IoT device or simulation using a well-known dataset, such as the NSL-KDD dataset. However, such approaches do not reflect the features that exist in real medical scenarios, leading to failure in potential threat detection. To address this problem, we proposed a novel intrusion classification architecture known as a Multi-class Classification based Intrusion Detection Model (M-IDM), which typically relies on data collected by real devices and the use of convolutional neural networks (i.e., it exhibits better performance compared with conventional machine learning algorithms, such as naïve Bayes, support vector machine (SVM)). Unlike existing studies, the proposed architecture employs the actual healthcare IoT environment of National Cancer Center in South Korea and actual network data from real medical devices, such as a patient’s monitors (i.e., electrocardiogram and thermometers). The proposed architecture classifies the data into multiple classes: Critical, informal, major, and minor, for intrusion detection. Further, we experimentally evaluated and compared its performance with those of other conventional machine learning algorithms, including naïve Bayes, SVM, and logistic regression, using neural networks.     

Machine Learning Approaches to Detect DoS and Their Effect on WSNs Lifetime

Energy and security remain the main two challenges in Wireless Sensor Networks (WSNs). Therefore, protecting these WSN networks from Denial of Service (DoS) and Distributed DoS (DDoS) is one of the WSN networks security tasks. Traditional packet deep scan systems that rely on open field inspection in transport layer security packets and the open field encryption trend are making machine learning-based systems the only viable choice for these types of attacks. This paper contributes to the evaluation of the use machine learning algorithms in WSN nodes traffic and their effect on WSN network life time. We examined the performance metrics of different machine learning classification categories such as K-Nearest Neighbour (KNN), Logistic Regression (LR), Support Vector Machine (SVM), Gboost, Decision Tree (DT), Naïve Bayes, Long Short Term Memory (LSTM), and Multi-Layer Perceptron (MLP) on a WSN-dataset in different sizes. The test results proved that the statistical and logical classification categories performed the best on numeric statistical datasets, and the Gboost algorithm showed the best performance compared to different algorithms on average of all performance metrics. The performance metrics used in these validations were accuracy, F1-score, False Positive Ratio (FPR), False Negative Ratio (FNR), and the training execution time. Moreover, the test results showed the Gboost algorithm got 99.6%, 98.8%, 0.4% 0.13% in accuracy, F1-score, FPR, and FNR, respectively. At training execution time, it obtained 1.41 s for the average of all training time execution datasets. In addition, this paper demonstrated that for the numeric statistical data type, the best results are in the size of the dataset ranging from 3000 to 6000 records and the percentage between categories is not less than 50% for each category with the other categories. Furthermore, this paper investigated the effect of Gboost on the WSN lifetime, which resulted in a 32% reduction compared to other Gboost-free scenarios.     

Compact Bat Algorithm with Deep Learning Model for Biomedical EEG EyeState Classification

Electroencephalography (EEG) eye state classification becomes an essential tool to identify the cognitive state of humans. It can be used in several fields such as motor imagery recognition, drug effect detection, emotion categorization, seizure detection, etc. With the latest advances in deep learning (DL) models, it is possible to design an accurate and prompt EEG EyeState classification problem. In this view, this study presents a novel compact bat algorithm with deep learning model for biomedical EEG EyeState classification (CBADL-BEESC) model. The major intention of the CBADL-BEESC technique aims to categorize the presence of EEG EyeState. The CBADL-BEESC model performs feature extraction using the ALexNet model which helps to produce useful feature vectors. In addition, extreme learning machine autoencoder (ELM-AE) model is applied to classify the EEG signals and the parameter tuning of the ELM-AE model is performed using CBA. The experimental result analysis of the CBADL-BEESC model is carried out on benchmark results and the comparative outcome reported the supremacy of the CBADL-BEESC model over the recent methods.     

Breast Cancer Detection in Saudi Arabian Women Using Hybrid Machine Learning on Mammographic Images

Breast cancer (BC) is the most common cause of women’s deaths worldwide. The mammography technique is the most important modality for the detection of BC. To detect abnormalities in mammographic images, the Breast Imaging Reporting and Data System (BI-RADs) is used as a baseline. The correct allocation of BI-RADs categories for mammographic images is always an interesting task, even for specialists. In this work, to detect and classify the mammogram images in BI-RADs, a novel hybrid model is presented using a convolutional neural network (CNN) with the integration of a support vector machine (SVM). The dataset used in this research was collected from different hospitals in the Qassim health cluster of Saudi Arabia. The collection of all categories of BI-RADs is one of the major contributions of this paper. Another significant contribution is the development of a hybrid approach through the integration of CNN and SVM. The proposed hybrid approach uses three CNN models to obtain ensemble CNN model results. This ensemble model saves the values to integrate them with SVM. The proposed system achieved a classification accuracy, sensitivity, specificity, precision, and F1-score of 93.6%, 94.8%, 96.9%, 96.6%, and 95.7%, respectively. The proposed model achieved better performance compared to previously available methods.