戊二醛的合成及应用

介绍了戊二醛合成方法的发展沿革，对吡啶法，吡喃法，戊二醇法，戊二酸法，环戊烯法等戊二醛的主要合成工艺进行述评，并对这些工艺进行了简单的比较，阐述了目前国内生产状况及戊二醛在消毒方面，帛革工业，石油工业等方面的应用。同时对戊二醛产品的市场前景作了简要的叙述。     

戊二醛消毒剂的特点与应用

简述了戊二醛生理性质。主要介绍了戊二醛消毒剂的使用特点和常用剂型使用方法。戊二醛消毒剂是一种灭菌谱广、杀菌力强、杀菌迅速、毒性低、使用安全方便的优良杀菌剂，可配制成酸性水溶液、碱性水溶液、含醇溶液、双组分型、复配增效型和粉状等不同剂型，且说明了这些不同剂型的特点。并提出戊二醛与表面活性剂、无机阳离子、抗菌剂和氧化剂复配是一个值得注意的发展方向。     

戊二醛的生产及应用

介绍了戊二醛的生产方法及其在消毒杀菌、石油开采、冷却水处理、有机合成等方面的应用，并展望了其市场前景。     

离子液体体系中环戊烯氧化合成戊二醛的研究

在离子液沐中，采用钨酸为催化剂，用过氧化氢水溶液为氧化剂，一步催化氧化环戊烯合成戊二醛。催化体系经4次循环，催化活性未见明显降低，并进一步讨论了CPE与H2O2物料配比、反应温度、反应时间对戊二醛收率的影响，并确定了最佳合成工艺条件：n（C5H8）：n（H2O2）=1：4，反应温度40℃，反应时间8hr。戊二醛总收率73％。     

戊二醛的生产与应用

综述了丙烯醛加成、1，5-戊二醇氧化、戊二酰氯还原和环戊烯（CPE）氧化等戊二醛的合成路线和制备方法，考察了目前戊二醛的生产厂家及其在皮革鞣剂，油田注水杀菌剂和医药杀菌等领域的应用市场。     

壳聚糖固定化As1.398中性蛋白酶稳定性的研究

研究了以中空球形壳聚糖固定As1．398中性蛋白酶的方法，分析了戊二醛浓度、给酶量对固定化的影响，并对固定化酶的性质进行了讨论。实验结果显示：戊二醛质量浓度为4％、每克载体给酶量25mg时，酶活力回收为65．4％，固定化酶的热稳定性、pH稳定性及乙醇的稳定性均高于游离酶。     

过氧酸条件下催化环戊烯氧化制备戊二醛的工艺研究

以环戊烯（CPE）为原料、在甲酸与过氧化氢形成的过氧甲酸体系中，以铌酸为催化剂一步合成戊二醛，考察了反应物配比、催化剂用量、反应温度、反应时间等对反应的影响。在最佳反应条件下，戊二醛的收率达到65％。该方法反应条件温和、高效节能，具有较好的工业化价值。     

戊二醛还原法制备纳米金及其类葡萄糖氧化酶活性测定

以聚乙烯吡咯烷酮为保护剂，戊二醛为还原剂，通过一步还原法制备纳米金，利用电子显微镜、纳米粒度分析仪和紫外分光光度计对其进行表征，并研究了合成条件对材料粒径、形貌以及分散性的影响，并检测了纳米金的类葡萄糖氧化酶（GOD）活性。结果表明合成最适条件为：65℃下在氯金酸和PVP质量比为1:1的混合溶液中迅速加入戊二醛（戊二醛与氯金酸的摩尔比为3:1），合成的纳米金分散性好，尺寸均一，平均粒径为7±0.2 nm，具有良好的类葡萄糖氧化酶活性。     

环戊烯氧化剂3戊二醛反应器的选型

根据小试和中试的实际情况，结合环戊烯氧化制戊二醛反应过程特点，确定首选带有搅拌的间歇釜式反应器，并就年产500吨戊二醛的工业规模进行了具体的反应器选型计算，可供实际生产设备选型参考。     

戊二醛的生产及应用

介绍了戊二醛的生产方法及其在消毒杀菌、石油开采、冷却水处理、有机合成等方面的应用,并展望了其市场前景。     

Improved Water Resistance and Adhesive Performance of a Commercial UF Resin Blended with Glutaraldehyde

The influence of glutaraldehyde blend on the properties of a commercially available resin in moist conditions was investigated. A UF resin with very low water resistance was blended with glutaraldehyde prior to the thermosetting step and the adhesive performance of the modified adhesive systems was studied. Experiments were performed on birch two-layer co-oriented plywood. It was shown that blending a commercial glue-mix as sold with glutaraldehyde can be an effective way to improve water resistance of the glue without introducing additional -NH₂ moiety. It was also found that glutaraldehyde does not deteriorate properties of the glue in the dry state, while glue susceptibility to boiling water is markedly reduced.     

Effect of processing parameters on the vulcanisation of natural rubber using glutaraldehyde

The process ability of vulcanising natural rubber using glutaraldehyde at low temperature has been studied. The main objective of this work is to improve the properties and stability of natural rubber (NR) using glutaraldehyde as a curing agent. In this study, the vulcanised samples were prepared systematically and compared with sulphur cured natural rubber vulcanisates. The influence of mole ratio of ammonia and glutaraldehyde, and the processing parameters (i.e. curing time and temperature) was investigated. The cured NR based on glutaraldehyde exhibited better hardness and thermal properties than that of the NR cured from conventional sulphur system. The experimental results reveal that the properties of glutaraldehyde cured NR can be developed with the proper additives combination and conditions adopted in the preparation. This cured system is very interesting due to it can be used for high temperature industrial applications. Moreover, it eases of processing at low temperature and cost.     

Improved Water Resistance and Adhesive Performance of a Commercial UF Resin Blended with Glutaraldehyde

The influence of glutaraldehyde blend on the properties of a commercially available resin in moist conditions was investigated. A UF resin with very low water resistance was blended with glutaraldehyde prior to the thermosetting step and the adhesive performance of the modified adhesive systems was studied. Experiments were performed on birch two-layer co-oriented plywood. It was shown that blending a commercial glue-mix as sold with glutaraldehyde can be an effective way to improve water resistance of the glue without introducing additional –NH₂ moiety. It was also found that glutaraldehyde does not deteriorate properties of the glue in the dry state, while glue susceptibility to boiling water is markedly reduced.     

Effect of “glutaraldehyde” functionality on network formation in poly(vinyl alcohol) membranes

The use of higher‐functionality oligomers of glutaraldehyde on network formation was investigated and compared with glutaraldehyde monomer in step‐growth reactions. The effect of using such oligomers in network formation depends on the stoichiometry, which alters either the branching or both the branching and crosslinking of the network. This was demonstrated in the properties of poly(vinyl alcohol) (PVA) networks crosslinked with glutaraldehyde using cryogenic scanning electron microscopy, water swelling studies, and protein transfer across membranes. General guidelines were given for the proper use of glutaraldehyde solutions. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 96: 780–792, 2005     

聚乙烯醇-海藻酸钙制备的影响因素

聚乙烯醇-海藻酸钙具有弹性好、柔韧性好和含水率高等优点。探讨了戊二醛用量、聚乙烯醇与海藻酸钠质量比、CaCl2质量分数、戊二醛与聚乙烯醇的反应时间对复合材料含水率的影响。实验结果表明当戊二醛质量分数为0.85%、聚乙烯醇与海藻酸钠质量比为8:1左右、CaCl2溶液质量分数达2%、戊二醛与聚乙烯醇的反应时间为1.5h时,复合材料的含水率最高,拉伸强度和扯断伸长率也都是最高的,其含水率达80.6%,拉伸强度达9.08MPa,扯断伸长率为400%。     

Influence of glutaraldehyde on the performance of a lignosulfonate/chitosan‐based medium density fiberboard adhesive

A lignosulfonate/chitosan‐based medium density fiberboard (MDF) adhesive has been prepared using glutaraldehyde as crosslinking agent. Optimization of glutaraldehyde/chitosan mass ratio was carried out based on characterization details involving MDFs’ mechanical and dimensional performances analysis, Fourier transform infrared spectroscopy, thermogravimetric analysis, and X‐ray diffraction. The addition of glutaraldehyde improved the mechanical properties of the MDF significantly, while it negatively affected the dimensional properties. The MDFs using lignosulfonate/chitosan‐glutaraldehyde adhesives (LS/CS‐Glu) with glutaraldehyde/chitosan mass ratios in the range of 0.25–0.75 fulfilled the Chinese national standard for MDF. Chitosan was crosslinked with self‐polymerized glutaraldehyde through C?N linkages which resulted in the reduction of the amide bonds and hydrogen bonds between chitosan and lignosulfonate. The proposed LS/CS‐Glu adhesives can be a promising candidate for traditional MDF adhesives which contain formaldehyde. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135, 45870.     

Crosslinking of Isabgol husk polysaccharides for microspheres development and its impact on particle size,swelling kinetics and thermal behavior

The microspheres were prepared by emulsification method using glutaraldehyde as crosslinker. The effects of variables as temperature, concentration of Isabgol husk and glutaraldehyde, and nature of dispersing media were analyzed on microsphere-derived properties such as size distribution, surface morphology, and swelling kinetics. The nature of crosslinking and interaction of polysaccharides structure with glutaraldehyde  were assessed by thermal analysis and infrared spectroscopy. The spherical and free flowing microspheres were obtained and a significant effect of process variables was observed on characteristics of formulations. The microspheres revealed their potential in the development of sustained release drug carriers for water soluble/insoluble drugs.     

Kinetics of crosslinking reaction of PVA membrane with glutaraldehyde

Prior to investigate the influences of degree of crosslinking on the hydrophilicity and mechanical strength of polyvinyl alcohol (PVA) membrane, the kinetics of crosslinking of PVA membrane with glutaraldehyde was examined. The reaction variables were temperature, hydroxyl group concentration of PVA membrane, and concentrations of glutaraldehyde and sulfuric acid in crosslinking solution. The overall reaction rate of crosslinking was suggested, which agrees well with the experimental results. The crosslinking reaction is approximately first order with respect to the concentration of hydroxyl group of PVA membrane, of glutaraldehyde, and of sulfuric acid. The activiation energy was estimated to be about 5.77 kcal/mol. It was also found that the degree of crosslinking of PVA membrane can be easily changed by controlling the reaction variables.     

影响戊二醛杀菌性能的因素

影响戊二醛杀菌效果的主要因素有浓度、ｐＨ值、温度、贮存时间、微生物类型、溶剂与添加剂等。对蛋白质的交联作用是其杀菌的主要方式。