Effects on executive function following damage to the prefrontal cortex in the rhesus monkey (Macaca mulatta).

[Correction Notice: An erratum for this article was reported in Vol 123(3) of Behavioral Neuroscience (see record 2009-07961-027). There was an error in the first sentence of the third full paragraph in the text on p. 235. The sentence should read “Based on the lesion reconstructions it was determined, as intended, that all monkeys had complete damage to areas 46, 8a, 8b, 9 and slight damage to area 10.”] Executive function is a term used to describe the cognitive processes subserved by the prefrontal cortex (PFC). An extensive body of work has characterized the effects of damage to the PFC in nonhuman primates, but it has focused primarily on the capacity of recognition and working memory. One limitation in studies of the functional parcellation of the PFC has been the absence of tests that assess executive function or its functional components. The current study used an adaptation of the Wisconsin Card Sorting Test, a classic test of frontal lobe and executive function in humans, to assess the effects of bilateral lesions in the dorsolateral PFC on executive function in the rhesus monkey (Macaca mulatta). The authors used the category set-shifting task, which requires the monkey to establish a pattern of responding to a specific category (color or shape) based on reward contingency, maintain that pattern of responding, and then shift to responding to a different category when the reward contingency changes. Rhesus monkeys with lesions of the dorsolateral PFC were impaired in abstraction, establishing a response pattern to a specific category and maintaining and shifting that response pattern on the category set-shifting task. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"The role of ventral and orbital prefrontal cortex in conditional visuomotor learning and strategy use in rhesus monkeys (Macaca mulatto)": Correction to Bussey et al (2001).

Reports an error in "The role of ventral and orbital prefrontal cortex in conditional visuomotor learning and strategy use in rhesus monkeys (Macaca mulatta)." by Timothy J. Bussey, Steven P. Wise and Elisabeth A. Murray (Behavioral Neuroscience, 2001[Oct], Vol 115[5], 971-982). In Figure 1 (p. 974), the extent of the intended lesions in the sections 32 and 28 mm from the interaural plane was misprinted. The correctly printed figure is shown in the erratum. (The following abstract of the original article appeared in record 2001-18882-001.) Four rhesus monkeys (Macaca mulatta) were trained to learn novel sets of visuomotor associations in 50 trials or less, within single test sessions. After bilateral ablation of the orbital and ventral prefrontal cortex, the monkeys lost the ability to learn these associations within a session, although they could learn them when given several daily sessions. Thus, relatively slow, across-session visuomotor learning depends on neither the ventral nor orbital prefrontal cortex, but rapid, within-session learning does. The ablations also eliminated at least 2 response strategies, repeat-stay and lose-shift, which might account, in part, for the deficit in rapid learning. The deficit is unlikely to result from a failure of visual discriminative ability or working memory: The monkeys could discriminate similar stimulus material within a session, and reducing the working memory load did not improve within-session learning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Prefrontal cortex and rule abstraction: Where and whether? Theoretical comment on Moore et al. (2009).

The primate dorsolateral prefrontal cortex is implicated in diverse aspects of behavioral regulation, cognitive control, and memory. However, direct neuropsychological evidence supporting a requirement of this area in functions other than spatial working memory has been scarce. T. L. Moore, S. P. Schettler, R. J. Killiany, D. L. Rosene, and M. B. Moss (see record 2009-04037-001) have shown, for the first time, that lesions of dorsolateral prefrontal cortex in the rhesus monkey (including areas 9 and 46) substantially impair performance in a test of executive function modeled on the Wisconsin Card Sorting Task. The pattern of impairment is consistent with a role for dorsolateral prefrontal areas in rule abstraction but may relate to a role for this area in rule maintenance as well. Interestingly, monkeys with dorsolateral prefrontal lesions do not appear to perseverate in their use of particular rules in the task, different from the common impairment associated with frontal lobe damage in humans. These findings indicate that dorsolateral prefrontal cortex is necessary for some aspects of rule-guided behavior in the primate brain and help illuminate the involvement of different prefrontal areas in different aspects of executive function and rule-guided behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The role of ventral and orbital prefrontal cortex in conditional visuomotor learning and strategy use in rhesus monkeys (Macaca mulatta).

[Correction Notice: An erratum for this article was reported in Vol 115(6) of Behavioral Neuroscience (see record 2007-17010-001). In Figure 1 (p. 974), the extent of the intended lesions in the sections 32 and 28 mm from the interaural plane was misprinted. The correctly printed figure is shown in the erratum.] Four rhesus monkeys (Macaca mulatta) were trained to learn novel sets of visuomotor associations in 50 trials or less, within single test sessions. After bilateral ablation of the orbital and ventral prefrontal cortex, the monkeys lost the ability to learn these associations within a session, although they could learn them when given several daily sessions. Thus, relatively slow, across-session visuomotor learning depends on neither the ventral nor orbital prefrontal cortex, but rapid, within-session learning does. The ablations also eliminated at least 2 response strategies, repeat-stay and lose-shift, which might account, in part, for the deficit in rapid learning. The deficit is unlikely to result from a failure of visual discriminative ability or working memory: The monkeys could discriminate similar stimulus material within a session, and reducing the working memory load did not improve within-session learning. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Impairment of executive function induced by hypertension in the Rhesus monkey (Macaca mulatta).

The effects of chronic, untreated hypertension on executive function were investigated in a nonhuman primate model of hypertensive cerebrovascular disease. Executive function was assessed with the Conceptual Set-Shifting Task (CSST), a task adapted from the human Wisconsin Card Sorting Test (WCST). Like the WCST, the CSST requires abstraction of a stimulus set, followed by a series of set shifts. Performance on the CSST by 7 young adult monkeys (Macaca mulatta) with surgically induced hypertension was compared with that of 6 normotensive monkeys. The hypertensive group was significantly impaired relative to the normotensive group in abstraction and set shifting. Although the neural basis of this impairment is unclear, evidence from studies with humans and monkeys suggests that the prefrontal cortex may be the locus for this effect of hypertension. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Bilateral neurotoxic amygdala lesions in rhesus monkeys (Macaca mulatta): Consistent pattern of behavior across different social contexts": Correction.

Reports an error in "Bilateral neurotoxic amygdala lesions in rhesus monkeys (Macaca mulatta): Consistent pattern of behavior across different social contexts" by Christopher J. Machado, Nathan J. Emery, John P. Capitanio, William A. Mason, Sally P. Mendoza and David G. Amaral (Behavioral Neuroscience, 2008[Apr], Vol 122[2], 251-266). In the aforementioned article, Table 1 on page 256 was incorrect. The correct table is printed in the erratum. (The following abstract of the original article appeared in record 2008-03769-001.) Although the amygdala has been repeatedly implicated in normal primate social behavior, great variability exists in the specific social and nonsocial behavioral changes observed in nonhuman primates with bilateral amygdala lesions. One plausible explanation pertains to differences in social context. This study measured the social behavior of amygdala-lesioned and unoperated rhesus monkeys (Macaca mulatta) in 2 contexts. Monkeys interacted in 4-member social groups over 32 test days. They were previously assessed in pairs (N. J. Emery et al., 2001) and were therefore familiar with each other at the beginning of this study. Across the 2 contexts, amygdala lesions produced a highly consistent pattern of social behavior. Operated monkeys engaged in more affiliative social interactions with control partners than did controls. In the course of their interactions, amygdala-lesioned monkeys also displayed an earlier decrease in nervous and fearful personality qualities than did controls. The increased exploration and sexual behavior recorded for amygdala-lesioned monkeys in pairs was not found in the 4-member groups. The authors concluded that the amygdala contributes to social inhibition and that this function transcends various social contexts. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"On the relationship between lateralized brain function and orienting asymmetries": Correction to Teufel et al. (2010).

Reports an error in "On the relationship between lateralized brain function and orienting asymmetries" by Christoph Teufel, Asif A. Ghazanfar and Julia Fischer (Behavioral Neuroscience, 2010[Aug], Vol 124[4], 437-445). In the article, we wrote that “the likelihood of obtaining at least one significant result at p n. The probability of obtaining at least one significant result is therefore 1 — (1— α)n. (The following abstract of the original article appeared in record 2010-16138-001.) Hemispheric specializations for language perception constitute one of the classic topic in cognitive neuroscience. Evidence has accumulated to suggest that lateralized acoustic processing is not restricted to humans but is also found in numerous animal species. One of the methods used to track such lateralization is the orienting-asymmetry paradigm, a simple, noninvasive means to study lateralization that has been applied to a range of different species ranging from harpy eagles to humans. Here we summarize and compare the results of studies employing the orienting-asymmetry paradigm, showing that these studies yield largely inconsistent results. We critically discuss the methodology's implicit assumptions and conclude that the empirical inconsistencies produced by the orienting-asymmetry paradigm, and the lack of sufficient evidence supporting the paradigm's underlying assumptions, warrant serious caution when interpreting results obtained by the method. Nontrivial interpretations of orienting-asymmetry results will require a much better understanding of how lateralized brain functions interact with overt behaviors. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

"Understanding and using the Implicit Association Test: I. An improved scoring algorithm": Correction to Greenwald et al. (2003).

Reports an error in "Understanding and using the Implicit Association Test: I. An improved scoring algorithm" by Anthony G. Greenwald, Brian A. Nosek and Mahzarin R. Banaji (Journal of Personality and Social Psychology, 2003[Aug], Vol 85[2], 197-216). The article contained several errors. On page 203, the data lines in Figure 2 are incorrectly labeled. As in Figure 1, the line with filled squares as data points should be labeled MEAN, the line with filled diamonds as data points should be labeled MEDIAN, and the line with unfilled squares as data points should be labeled RECIPROCAL. (The following abstract of the original article appeared in record 2003-05897-003.) In reporting Implicit Association Test (IAT) results, researchers have most often used scoring conventions described in the first publication of the IAT (A. G. Greenwald, D. E. McGhee, & J. L. K. Schwartz, 1998). Demonstration IATs available on the Internet have produced large data sets that were used in the current article to evaluate alternative scoring procedures. Candidate new algorithms were examined in terms of their (a) correlations with parallel self-report measures, (b) resistance to an artifact associated with speed of responding, (c) internal consistency, (d) sensitivity to known influences on IAT measures, and (e) resistance to known procedural influences. The best-performing measure incorporates data from the IAT's practice trials, uses a metric that is calibrated by each respondent's latency variability, and includes a latency penalty for errors. This new algorithm strongly outperforms the earlier (conventional) procedure. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Differential involvement of the dorsal anterior cingulate and prelimbic-infralimbic areas of the rodent prefrontal cortex in spatial working memory": Correction to Ragozzino et al. (1998).

Reports an error in "Differential involvement of the dorsal anterior cingulate and prelimbic-infralimbic areas of the rodent prefrontal cortex in spatial working memory" by Michael E. Ragozzino, Spencer Adams and Raymond P. Kesner (Behavioral Neuroscience, 1998[Apr], Vol 112[2], 293-303). Figure 1 (page 295) and Figure 4 (page 299) were printed incorrectly. The corrected figure pages and corresponding captions are provided in the erratum. (The following abstract of the original article appeared in record 1998-01023-003.) The present study examined the effects of quinolinic acid lesions of the dorsal anterior cingulate and prelimbic-infralimbic cortices on spatial working memory and spatial discrimination using go/no-go procedures. All testing occurred in a 12-arm radial maze. In a working memory task, rats were allowed to enter 12 arms for a cereal reward. Three or 4 arms were presented for a 2nd time in a session, which did not result in a reward. In a spatial discrimination task, rats had successive access to 2 different arms. One arm always contained a reward, and the other never contained a reward. Prelimbic-infralimbic lesions impaired spatial working memory but only produced a transient spatial discrimination deficit. Dorsal anterior cingulate lesions did not induce a deficit in either task. These findings suggest that the prelimbic-infralimbic cortices, but not the anterior cingulate cortex, are important in spatial working memory. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Entorhinal cortex lesions disrupt the transition between the use of intra- and extramaze cues for navigation in the water maze": Correction to Oswald et al. (2003).

Reports an error in "Entorhinal cortex lesions disrupt the transition between the use of intra- and extramaze cues for navigation in the water maze" by C. J. P. Oswald, D. M. Bannerman, B. K. Yee, J. N. P. Rawlins, R. C. Honey and M. Good (Behavioral Neuroscience, 2003[Jun], Vol 117[3], 588-595). The definitions "Present = intramaze landmark present during Stage 2" and "Absent = intramaze landmark absent during Stage 2" appear incorrectly in the caption to Figure 3. These terms and definitions should appear in the caption to Figure 4. (The following abstract of the original article appeared in record 2003-05069-018.) This study with rats examined the effects of excitotoxic lesions to the entorhinal cortex (EC) and hippocampus (HPC) on using extramaze and intramaze cues to navigate to a hidden platform in a water maze. HPC lesions resulted in a disruption to the use of extramaze cues, but not intramaze cues, whereas EC lesions had no effect on the use of these cues when they were encountered for the fast time. However, prior navigation training in which 1 type of cue was relevant disrupted navigation with the other type in rats with EC lesions. Results show that the EC contributes to the processing of spatial information, but that this contribution is most apparent when there is a conflict between 2 sources of navigational cues in the water maze. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Clinician bias in the diagnosis of posttraumatic stress disorder and borderline personality disorder": Correction to Woodward et al. (2009).

Reports an error in "Clinician bias in the diagnosis of posttraumatic stress disorder and borderline personality disorder" by Halley E. Woodward, Casey T. Taft, Richard A. Gordon and Laura A. Meis (Psychological Trauma: Theory, Research, Practice, and Policy, 2009[Dec], Vol 1[4], 282-290). In this article, the copyright attribution is incorrect. The article is in the public domain. (The following abstract of the original article appeared in record 2009-23661-003.) A sample of volunteers from a group of randomly selected psychologists in New York State (N = 119) provided a primary diagnosis and rule-out diagnoses for a case vignette that included balanced criteria for borderline personality disorder (BPD) and posttraumatic stress disorder (PTSD) in a mail survey. Vignettes portrayed a male or a female client, and history of childhood sexual abuse was presented either first or last. Results indicated that cognitive–behavioral therapy (CBT) clinicians were more likely to diagnose PTSD than BPD or other disorders, and psychodynamic clinicians were more likely to diagnose BPD or other disorders than PTSD. An anchoring effect (i.e., evidence that one regards initial information as an anchor that may or may not be adjusted upon exposure to subsequent information) of abuse history presentation was found. Findings did not support a patient or clinician gender bias. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Reasoning about the disclosure of success and failure to friends among children in the United States and China": Correction to Heyman et al. (2008).

Reports an error in "Reasoning about the disclosure of success and failure to friends among children in the United States and China" by Gail D. Heyman, Genyue Fu and Kang Lee (Developmental Psychology, 2008[Jul], Vol 44[4], 908-918). An error was introduced in the production process. The heading for the bottom half of Table 1 should be "China," not "Canada." (The following abstract of the original article appeared in record 2008-08592-002.) Children's reasoning about individuals' willingness to disclose their successes and failures was investigated among 194 6- to 11-year-olds in the United States and China. In Study 1, participants showed a valence-matching effect, in which they predicted that individuals would be more likely to disclose their performance to an audience of friends if the friends' level of achievement was similar rather than dissimilar. This effect was weaker among children from China, who were more likely to justify their responses with reference to the implications for learning together or improving future performance. Results of Study 2 suggest that for children from the United States, the disclosure of successful performance to a friend who has performed poorly is seen as implicitly conveying the message "I'm better than you," whereas for children from China the message is "I can help you to do better." Results are interpreted with reference to cultural values and expectations about helping others to learn. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Psychology in extremis: Preventing problems of professional competence in dangerous practice settings": Correction to Johnson et al. (2011).

Reports an error in "Psychology in extremis: Preventing problems of professional competence in dangerous practice settings" by W. Brad Johnson, Shannon J. Johnson, Glenn R. Sullivan, Bruce Bongar, Laurence Miller and Morgan T. Sammons (Professional Psychology: Research and Practice, 2011[Feb], Vol 42[1], 94-104). The title and authors for the first section of the article, beginning of the first column on page 95, were inadvertently omitted. The section should have begun with the following: “In Extremis Practice: Ensuring Competence During and After Deployment to a Combat Zone,” by W. Brad Johnson and Shannon J. Johnson. (The following abstract of the original article appeared in record 2011-04544-013.) When a psychologist provides services in a dangerous context—a work setting defined by persistent threat to the psychologist's own personal safety and well-being—the psychologist is said to practice in extremis. Psychologists who routinely function in extremis, such as those in correctional, disaster response, military, and police psychology—among other specialties—may be at increased risk for troubling experiences such as direct or vicarious traumatization, compassion fatigue, and empathy failure. Over time, in extremis experiences may contribute to decrements in professional competence. When psychologists become aware of personal problems that interfere with their work, they must take steps to ameliorate the problem while protecting consumers. In this Focus on Ethics, we discuss the difficulty inherent in self-identifying and correcting problems of professional competence when working in a high-threat environment. Three expert commentaries further elucidate in extremis competency concerns from the perspective of disaster response, police, and military psychology. The authors provide numerous recommendations for helping psychologists to ensure ongoing competence in in extremis jobs. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

"Ovarian hormones and cognition in the aged female rat: I. Long-term, but not short-term, ovariectomy enhances spatial performance": Correction to Bimonte-Nelson et al. (2003).

Reports an error in "Ovarian Hormones and Cognition in the Aged Female Rat: I. Long-Term, but Not Short-Term, Ovariectomy Enhances Spatial Performance" by Heather A. Bimonte-Nelson, Rachel S. Singleton, Christopher L. Hunter, Kimber L. Price, Alfred B. Moore and Ann-Charlotte E. Granholm (Behavioral Neuroscience, 2003[Dec], Vol 117[6], 1395-1406). The fifth sentence of the abstract reads, "Aged rats exhibited estradiol and elevated progesterone levels comparable to those of young rats." The sentence should read as follows: "Aged rats exhibited similar estradiol and elevated progesterone levels compared with those of young rats." (The following abstract of the original article appeared in record 2003-10460-025.) Although research suggests that ovariectomy (ovx) is detrimental to spatial cognition in young rats, little work has evaluated the cognitive effects of ovx in aged rats. The authors investigated the effects of ovx in aged rats using the water radial-arm maze. In Study 1, young rats and aged rats receiving ovx 1.5 months before testing outperformed aged rats receiving sham surgery or ovx 21 days before testing. In Study 2, young rats and aged rats receiving ovx 2.0 or 6.0 months before testing outperformed aged sham rats. Aged rats exhibited estradiol and elevated progesterone levels comparable to those of young rats. The findings suggest that 1.5-6.0 months, but not 21 days, of ovx improves spatial memory in aged rats. The hypothesis that long-term ovarian hormone loss is detrimental to spatial memory in aged rats was not supported. The authors hypothesize that removal of elevated progesterone levels is related to the ovx-induced cognitive enhancement. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Treating traumatized OEF/OIF veterans: How does trauma treament affect the clinician?": Correction to Voss Horrell et al. (2011).

Reports an error in "Treating traumatized OEF/OIF veterans: How does trauma treatment affect the clinician" by Sarah C. Voss Horrell, Dana R. Holohan, Lea M. Didion and G. Todd Vance (Professional Psychology: Research and Practice, 2011[Feb], Vol 42[1], 79-86). The word “While” was erroneously inserted in the first sentence of the “Clinician Factors” section. The corrected sentence is provided in the erratum. (The following abstract of the original article appeared in record 2011-04544-011.) The authors of this article describe the rewards and challenges for clinicians treating veterans who have served in Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF). Issues of vicarious trauma, secondary traumatic stress, compassion fatigue, and burnout are defined and reviewed, as are compassion satisfaction and posttraumatic growth. Patient, clinician, and organizational characteristics that are likely to affect clinicians working with this clinical population are discussed. Patient factors that may increase strain on clinicians are discussed such as age, likelihood of redeployment, comorbid conditions, attendance issues, and elevated risk for suicide and aggression. Clinician factors, such as theoretical orientation, training, supervision, military affiliation, personal trauma history, spirituality, social support, and self-care, are also discussed as possible risk and protective factors for vicarious trauma and burnout. Organizational influences, such as caseload size and diversity, clinician control and autonomy, use of evidence-based practices, availability of resources, rural isolation, and the philosophy of the clinic, are further discussed. Recommendations for ameliorating risks are discussed relative to each area and include allowing clinicians to plan their own appointments so as to balance their caseload of OEF/OIF veterans, attending to self-care practices, and having a supportive team with thorough training in evidence-based practices. Future empirical research is needed on risk and resiliency factors for clinicians working with traumatized OEF/OIF veterans given that this population is likely to grow. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

"Social influences on the selection of a protein-sufficient diet by Norway rats (Rattus norvegicus)": Correction to Beck and Galef (1989).

Reports an error in "Social influences on the selection of a protein-sufficient diet by Norway rats (Rattus norvegicus)" by Matthew Beck and Bennett G. Galef (Journal of Comparative Psychology, 1989[Jun], Vol 103[2], 132-139). There was a misstatement. On page 137, second column, second paragraph, the sentence that begins on line 7 ought to read as follows: Protected t tests revealed that subjects in the Different Food-Same Place Group gained a significantly smaller percentage of body weight than did subjects in each of the other two groups (LSD = .67, both ps 1989-31944-001.) Investigated effects of interactions between naive and knowledgeable rats (Rattus norvegicus) on selection of a nutritionally adequate diet by the naive. We found that during a 7-day test, isolated rats choosing among 4 foods, 3 of which were protein-deficient and 1 of which was protein-rich, failed to learn to prefer the protein-rich diet and lost weight. Conversely, those rats that interacted with conspecifics trained to eat the protein-rich diet developed a strong preference for that diet and thrived. The authors also found that Ss were more strongly influenced in their diet selection by the flavor of the foods eaten by conspecifics than by the locations where conspecifics fed. The results suggest that social influence may be important in development of adaptive patterns of diet choice by rats (or other dietary generalists) that need to find nutritionally adequate diets in demanding environments. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social competence of adult chimpanzees (Pan troglodytes) with severe deprivation history: I. An individual approach": Correction to Kalcher-Sommersguter et al. (2011).

Reports an error in "Social competence of adult chimpanzees (Pan troglodytes) with severe deprivation history: I. An individual approach" by Elfriede Kalcher-Sommersguter, Signe Preuschoft, Karl Crailsheim and Cornelia Franz (Developmental Psychology, 2011[Jan], Vol 47[1], 77-90). Table 4 (p. 86) contained an error. The development of stationary vicinity for LD (late deprived) chimpanzees is misstated as ns. However, the difference is highly significant as p = .008. (The following abstract of the original article appeared in record 2011-00627-005.) Early social deprivation in highly social mammals interferes with their varying needs for security and stimulation. Toleration of social stimulation was studied in 18 adult ex-laboratory chimpanzees, who had been deprived for 16 to 27 years, during their 1st year after resocialization into 1 of 3 social groups. For this, a model of social competence was developed with 5 grades of social stimulation. The chimpanzees were classified as either early deprived (EDs; M = 1.2 years) or late deprived (LDs; M = 3.6 years) according to their age at entering the laboratory. EDs did not differ significantly from LD chimpanzees in the first 3 grades of social stimulation (i.e., the toleration of stationary vicinity, initiation of brief sociopositive contacts and gentle social play). LDs, however, clearly exceeded EDs in the 4th and 5th grade of social stimulation (i.e., their engagement in allogrooming and their toleration of passive close proximity). Furthermore, LDs showed greater social initiative in changing a social situation and had more expanded grooming networks compared with EDs. Moreover, in LDs and ED females, but not in ED males, toleration of stationary vicinity increased from the 1st to the 2nd year of group living. (PsycINFO Database Record (c) 2011 APA, all rights reserved)