温米退积型与进积型浅水辫状河三角洲沉积模式

不同类型辫状河三角洲的成因分析是预测剩余油分布及制定合理开发政策的基础.岩石地球化学及成因地层分析表明.温米油田三间房组是在气候干燥的淡水湖盆长期基准面旋回内的退积型和进积型浅水辫状河三角洲沉积.应用精细成因地层对比方法建立三间房组单砂层成因地层格架.基于单分流河道识别:退积型辨状河三角洲规模小,分流河道宽深比30～58,平面形态纵向由枝状向指状演化,发育CSm→MSp-1→FSh→FSp-h→FStr→FSp-h→Fr较细岩石相组合;进积型辫状河三角洲规模相对较大.分流河道宽深比53～108,平面形态纵向呈指状-枝状一片状演化.发育SCm→GCSm→CStr→FSp-h→FSp-l较粗岩石相组合.湖底坡折带发育小型河口坝,水气交替注入能较大幅度提高这类油藏的采收率.     

海拉尔盆地贝尔凹陷贝西地区南屯组层序地层特征

应用沉积学和层序地层学的原理和方法,利用地震、钻井、岩心等资料,结合盆地区域构造演化特征,建立了海拉尔盆地贝尔凹陷贝西地区南屯组层序地层格架,将南屯组划分为1个超层序、4个三级层序、11个体系域.在层序格架内共识别出扇三角洲、辫状河三角洲、湖底扇、湖泊4种主要沉积相类型及8种亚相类型.南屯组沉积时期区内经历了初始沉降一快速沉降一沉降减弱一萎缩的构造演化过程,并形成与其对应的4个三级层序:SQ1沉积时期,研究区为分割的断陷盆地,湖盆规模较小,主要发育扇(辫状河)三角洲;SQ2沉积时期,湖盆规模迅速增大,统一的湖盆基本形成,沉积格局与SQ1时期相似·但有所不同的是区内西南缘出现物源供给,形成扇三角洲沉积;SQ3沉积时期,湖盆规模最大,区内各个物源方向的扇(辫状河)三角洲沉积规模明显减小,湖底扇及滑塌浊积体等重力流深水沉积相对发育;SQ4沉积时期,湖盆萎缩,湖盆规模迅速减小,同时东南部物源供给不足,造成东南部辫状河三角洲沉积几乎消失.生储盖组合及成藏条件综合分析表明:SQ2、SQ3低位体系域及高位体系域发育优质储层,并由于紧邻规模较大的烃源岩,在邻近断裂发育地区易形成断块圈闭及断背斜圈闭;在斜坡地区和缓坡带可形成不整合面作为遮挡的不整合-岩性圈闭及以各类砂体作为储集空间的地层超覆圈闭.     

塔南凹陷东部构造带南屯组储层宏观非均质性对油气分布的影响

塔南凹陷东部构造带南屯组地层主要发育近岸水下扇沉积,局部发育三角洲沉积.复杂的沉积充填样式塑造了本区复杂的岩性油藏.在细分地层单元内对储层岩性、物性、含油性统计分析的基础上,优选多种储层非均质性分类方案,结合砂体成因、叠置样式、平面展布特征以及渗透率韵律性等方面的分析,按照层间、平面、层内3个层次对储层宏观非均质性进行了解剖分析.结果表明:层序旋回对储层垂向岩性、物性的变化具有控制作用;凝灰质的发育对南屯组储层具有破坏作用,影响油气的运聚;水下分流沟道及河道砂是油气聚集的主要砂体类型;水下扇中扇是油气主要聚集区带.     

宝北三工河组储层沉积特征精细研究及应用

辫状河三角洲是我国油气藏比较常见的沉积体系,沉积环境复杂多变,在同一沉积亚相中仍然存在具有明显沉积韵律、岩石相组合的小的沉积单元.通过岩心剖面对比,将辫状(水下)分流河道细分为充填河道、废弃河道和进积河道三个小的沉积单元,并结合开发动态特征分析了不同沉积单元对开发过程的影响,具有明显的规律性.精细研究油藏沉积特征对提高油田采收率具有现实意义.     

福山凹陷花场北部流一段储层沉积特征

为解决福山凹陷中特低渗透储量比例大、注水开发矛盾突出的问题,利用岩芯、测井、录井等资料,探讨花场地区流一段储层的岩石类型、构造特征,分析储层的岩相特征,明确储层的沉积环境。利用测井曲线和岩屑描述建立沉积微相的测井相模式,探究砂体的分布规律。结果表明:花场北部流一段储层发育两点物源,主要发育辫状河三角洲前缘亚相沉积;微相类型包括水下分流河道、河口坝、席状砂等5种类型;流一段储层沉积的砂体以水下分流河道为主,砂体分布具有明显规律性和方向性,水下分流河道的砂体宽度较大,由南至北呈叶状展布。该研究可为福山凹陷进一步的勘探与开发提供一定的理论依据。     

地震沉积学在识别陆相湖泊浊积砂体中的应用

地震沉积学是一门新兴边缘交叉学科,它以三维地震数据为基础,结合岩心、测井等资料.通过先进的地球物理技术,对沉积微相进行精细研究.胜利油田滨682井区沙三中、下亚段以近岸水下扇、浊流和半深湖一深湖沉积为主,浊积砂是该层主要的产油砂体.为了分析该地区浊积砂的分布规律,在地震沉积学理论指导下,运用90°相位调整技术和地层切片技术对滨682井区目的层段进行了研究.研究结果认为:垂向上,滨682井区沙三下亚段的下部和上部以及沙三中亚段的下部和上部是浊积砂体发育的有利层段;在平面上,沙三下亚段沉积早期浊积砂体主要发育在研究区东南部,面积最大可迭1.71 km2;沙三下亚段沉积晚期浊积砂体在东部、东南部和南部都有发育.南部浊积砂体面积较大,可达3.37 km0,东南部和东部浊积砂体面积较小,在1.61 km2左右;沙三中亚段沉积早期浊积砂体发育在研究区东北和东南,面积可达1.90 km2;沙三中亚段沉积晚期浊积砂体发育在研究区西部和东南部,面积都较小,一般为1.15km2.     

鄂尔多斯盆地演武地区延安组延10油层组沉积相研究

演武地区延10段是鄂尔多斯盆地延安组重要油层组之一,但对其沉积相的相关研究较为贫乏。结合整个鄂尔多斯盆地的构造及沉积演化特征,通过对演武地区延10段的岩石学特征、泥岩颜色、沉积构造等特征的综合研究,并结合沉积岩石学、层序地层学、岩相古地理等地质理论,认为演武地区延10油层组属于河流沉积体系,发育辫状河相,并进一步将其划分为河道砂坝、泛滥平原等两个沉积微相。根据延10段沉积微相的展布及演化规律,并结合其区域沉积和构造背景,建立了研究区延10油层组的沉积模式。     

柴西南阿拉尔地区古近纪—新近纪地层结构及环境特征

为研究阿拉尔地区古近纪—新近纪地层结构及环境特征,在野外岩芯观察和描述的基础上,对研究区地层结构类型进行划分和形成机理解释,识别出各时期地层结构类型并结合古生物特征,最终进行环境特征综合分析。结果表明:地层结构包括均质型和非均质型(互层式、夹层式、进积型、退积型和无序多层式);各地层结构的形成与沉积物供给速率同可容空间速率之间的对比差异有关;下干柴沟组—下油砂山组时期识别出扇三角洲平原和滨浅湖2种沉积亚相及部分微相类型,表现为扇三角洲平原和滨浅湖交替沉积,湖平面多次升降旋回,气候经历了温凉干旱—暖热—半干旱—干旱加剧,水体逐渐咸化,沉积环境由还原转向氧化。     

百口泉地区二叠系下乌尔禾组沉积特征研究及有利储层预测

百口泉地区二叠系下乌尔禾组发育一套近源的粗粒碎屑沉积。目前针对该区的研究资料较少,沉积相类型仍有争议,生产矛盾突出,对后期油藏开发研究工作造成很大困难。通过岩心观察,结合测录井和分析化验对百口泉油田二叠系下乌尔禾组沉积相进行研究。研究表明,下乌尔禾组发育一套扇三角洲沉积,而不是辫状河三角洲沉积体,可识别出扇三角洲前缘、前三角洲2个亚相以及扇面河道,水下分支河道等6个微相。结合该区试油成果及物性资料分析,得出牵引流成因的水下分支河道微相含油性较好,为有利储层;而碎屑流等重力流成因的储层,含油性较差,可视为差储层。为该区的后续勘探开发、评价提供思路和方法,也为克拉玛依油田及其他扇三角洲发育区的油气勘探研究工作提供借鉴。     

斜坡区岩性地层圈闭识别技术与应用——以歧口凹陷滨海地区东部为例

为了揭示歧口凹陷古近系岩性地层油气藏分布规律并指导钻探,应用层序地层学理论,结合三维地震、测井和岩心资料对岐口凹陷滨海地区古近系开展了层序地层分析.古近系作为一个超层序组发育3个超层序、11个三级层序.根据同沉积构造坡折类型,可以把层序划分为挠曲坡折型层序和断坡型层序2种层序类型.其中:断坡型层序主要发育在超层序1,挠曲坡折型层序主要发育在超层序2和超层序3.在滨海斜坡区,超层序2和超层序3由挠、由坡折控制的层序低位体系域和高位体系域砂体与湖扩展体系域优质烃源岩配置良好、埋深适中、成藏条件优越,是地层岩性油气藏发育有利区.提出了模型正演和有效数计算相结合的地震属性优选方法及地震属性控制下的储层预测技术,并利用该项技术在有利区内预测了6个有利目标.     

Regional differences in suicide in Hungary in the light of registered cases of depression

Author made a revision on the theory published by Rihmer and alii in the year 1989. According to this theory the marked regional differences of suicide in Hungary are caused by the different discovery of the "endogen depression" (rate of diagnosed depression). So the lower is the diagnosis of depression the higher is the suicide rate in a given territory. They have seen a negative correlation between the number of working physicians and the suicide rates. Author made a reexamination on a correct database between 1985-1994. He has also made a study using the DSM-III-R diagnostic criteria in four counties of Hungary. His results deny the theory above mentioned. The rank-correlation of the number of GP and the suicide rates in Hungary in years 1985-1994 did not show correlation. So the underdiagnosis of the depressive disorders and the different number of GP are not the cause of the regional differences of suicide in Hungary.     

Role of clozapine in the occurrence of chromosomal abnormalities in human bone-marrow cells in vivo and in cultured lymphocytes in vitro

Bone-marrow chromosomes were examined from 38 mentally and physically retarded and two psychiatric patients who were being treated with a variety of neuropharmacologic drugs. Twenty of these patients used clozapine (Leponex). The clastogenic effects of clozapine in vitro were studied in the lymphocyte cultures of three patients--one free of hematologic disease and two who 6 months earlier had had agranulocytosis attributed to the use of clozapine. The mean frequency of cytogenetic abnormalities in the bone-marrow cells of patients who used clozapine was significantly increased (P less than 0.05). The two patients who had had agranulocytosis had a greater frequency of cytogenetic abnormalities in their cultured lymphocytes in vivo and in vitro than the patient free of hematologic disease. A clone with a 13/14 chromosome translocation was detected in one of the patients. As all patients received a number of drugs during the in vivo and in vitro studies no definite conclusions could be drawn regarding the role played by clozapine in the occurrence of chromosomal abnormalities.     

Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo

The aim of the present study was to test the ability of the chemotherapeutic agent suramin to inhibit angiogenesis in experimental models in vitro and in vivo. In the culture of rat aortic rings on fibronectin, suramin dose-dependently inhibited vascular cell growth, achieving the maximal effect (mean - 88% versus controls, P < 0.05) at 400 microg/ml. Image analysis showed that suramin could inhibit microvessel sprouting in fibrin from rat aortic rings as evaluated by the ratio between the cellular area and the mean gray value of the sample (sprouting index); suramin at 50 microg/ml significantly reduced the sprouting index from the control value of 0.35+/-0.04 to 0.14+/-0.02 mm2/gray level (P < 0.05). Likewise, the area occupied by cells was 19.2+/-1.8 mm2 as compared with 41.8+/-4.2 mm2 in controls (P < 0.05). In the rat model of neovascularization induced in the cornea by chemical injury, suramin at 1.6 mg/eye per day reduced the length of blood vessels (0.7+/-0.1 mm as compared with 1.5+/-0.1 mm in controls, P < 0.05). In the same model the ratio between the area of blood vessels and the total area of the cornea (area fraction score) was decreased by suramin from 0.19+/-0.02 in controls to 0.03+/-0.003 (P < 0.05). Suramin given i.p. at 30 mg/ kg per day markedly inhibited the neovascularization induced in the rat mesentery by compound 48/80 or conditioned medium from cells secreting the angiogenic protein fibroblast growth factor-3 (FGF-3). The area fraction score in control rats treated with compound 48/80 was 0.31+/-0.03, and this was reduced to 0.07+/-0.01 by suramin (P < 0.05). After i.p. administration of FGF-3 the area fraction score was reduced by suramin from 0.29+/-0.03 to 0.05+/-0.01 (P < 0.05). These results provide evidence that suramin exerts inhibitory effects on angiogenesis in both in vitro and in vivo models.     

Difference in changes of plasma volume in two types of Goldblatt hypertension in rabbits

High plasma renin concentration (PRC) and hematocrit (Ht) were observed in hypertensive rabbits with one renal artery clipped and an intact opposite kidney (Group A), while rather low PRC and Ht in hypertensive ones with one renal artery clipped and the opposite kidney removed (Group B). Plasma volume (PV), blood volume (BV), and packed cell volume (PCV) were estimated in these two types of hypertensive rabbits, and also in sham-operated rabbits (Group C). In Group A, 4 weeks after clipping of a renal artery, PV was decreased and significant inverse correlations were observed between PV and the elevation of blood pressure and between PV and PRC. A significant correlation between PRC and the elevation of blood pressure was also found 4 and 12 weeks after the clipping. PCV was increased until 12 weeks after clipping. In Group B, PV was increased 1 and 4 weeks after clipping, then returned to the initial level. Ht was decreased 1 and 12 weeks, and PCV was decreased 12 weeks after clipping. These results would indicate that a high Ht seen in Group A was partly due to the decreased PV and partly due to the increased PCV, while, in Group B, a low Ht in early stage might be mainly due to the increased PV, but in the late stage, a decreased PCV appeared to play a role to lower Ht. PRC seems to be affected differently by PV in these two types of hypertension.     

CS1000在天铁烧结生产过程控制中的应用

结合天津铁厂烧结分厂二烧车间烧结过程控制的具体情况,介绍了分散型控制系统在烧结生产上的应用以及数据网上发布的一种方法。     

Efficacy of lomefloxacin in treatment of nonspecific inflammatory diseases and in prophylaxis of postoperative complications in urology

Clinical and bacteriological efficacies of lomefloxacin and ofloxacin were comparatively estimated in the treatment of 104 urologic patients with nonspecific inflammatory diseases and in 36 urologic patients for prophylaxis of inflammatory complications after surgical interventions. The majority of the urinary tract pathogens i.e. Enterobacteriaceae spp. and gramnegative nonfermenting bacteria were highly susceptible to both the fluoroquinolones. The clinical and bacteriological efficacies of lomefloxacin amounted to 94.4 and 80.7 per cent and those of ofloxacin to 92 and 79.2 per cent respectively. The prophylactic use of lomefloxacin and ofloxacin was efficient in 94.7 and 94.1 per cent of the cases respectively. The antibacterial prophylaxis in urologic patients should be applied not only at the period of surgical interventions but also during the early postoperative period.     

Epidemiology of trichinellosis in lynx in Finland

To examine the possibility of cytokine gene therapy in relation to pancreatic cancer, we evaluated the antitumor effect of human pancreatic carcinoma cells (AsPC-1) which were retrovirally-transduced with several kinds of cytokine genes. These cells were inoculated into BALB/c nude mice and their tumor volumes were assessed. The in vitro growth rate of the transduced cells was not different from that of a parental cell line. Among the transduced cells, human interleukin (IL)-6-transduced AsPC-1 and mouse granulocyte macrophage colony-stimulating factor-transduced AsPC-1 cells showed a significant retardation of tumor growth compared with a parental cell line. In the cases of AsPC-1 cells transduced with the human IL-2 or mouse IL-4 gene, small tumors were generated but thereafter they regressed completely. Histological examinations showed monocytic cell infiltration around the tumors of IL-2- or IL-4-producing cells. These data suggest that secretion of IL-2 or IL-4 from tumor cells can induce an antitumor effect even in the defective condition of mature T cells.