Untersuchungen der Pränataltoxizität von Butenylisothiocyanat an Ratten

Prenatal toxicity study of butenyl isothiocyanate in rats Butenyl isothiocyanate (BylITC), the hydrolysis product of the glucosinolate gluconapin, present in various cruciferous vegetables and in rapeseed, was administered in oral doses of 0, 50, 100 and 150 mg/kg to pregnant rats on day 12 to 19 of gestation. Maternal toxicity was indicated by reduced body weight gain and increases in the weights of liver and kidneys. BylITC doses of 100 and 150 mg/kg caused retardation of fetal growth and ossification.     

Zur Wirkung von 2,4-Dichlorphenol auf Enzymaktivitäten und andere Parameter in parenchymatösen Organen von Ratten

Effects of 2,4-dichlorophenol on enzyme activities and other parameters in parenchymatous organs of rats After repeated administration of 2,4-dichlorophenol the aminopeptidases AAP and LAP, and the alkaline phosphatase in various organs were influenced. The treatment causes stimulatory or inhibitory activities. Also with histological and histochemical methods damages could be detected.