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1.
The objective of the study was to determine sensory and objective characteristics of broiler breast and thigh meat from commercial broilers fed rendered spent hen meal (RSHM) from hatch to 42 d of age. Breast and thigh muscles from 90, 6-wk-old straight-run broilers (i.e., mixed male and female broilers) fed starter and grower diets consisting of either 0, 8, or 12% RSHM were evaluated for sensory characteristics, instrumental texture, and compositional profiles. The RSHM treatments had no adverse effects (P > 0.05) on juiciness, chicken flavor intensity, tenderness, or compositional profiles for the breast or thigh meats. Off-flavor scores for all treatments were above the threshold value, indicating that the RSHM imparted no off-flavors to the breast and thigh meats. Warner-Bratzler shear measurements were similar (P > 0.05) for breast meat from broilers in all treatments. No shear measurements were conducted for the thigh meat. It was concluded that RSHM can be incorporated into the diets of broilers at levels of up to 12% without causing objectionable sensory characteristics in the cooked broiler meat.  相似文献   

2.
OBJECTIVES: The aim of this study was to determine the effects of Cl- channel blockers on the cardiac cystic fibrosis transmembrane conductance regulator (CFTR) Cl- current (ICl) and the protein kinase A-regulated L-type calcium current (PKA-ICa). METHODS: Whole-cell ICl and ICa were recorded from isolated guinea pig ventricular myocytes using the patch clamp technique during stimulation of PKA by forskolin (1 or 2 microM). RESULTS: The inhibitory effects of clofibric acid, p-chlorophenoxy propionic acid, gemfibrozil, diphenylamine-2-carboxylate (DPC), anthracene-9-carboxylate, 4,4'dinitrostilbene-2,2'-disulfonic acid and indanyloxyacetic acid 94 were examined on the two currents. Clofibric acid (1 mM), p-chlorophenoxy propionic acid (1 mM) and gemfibrozil (250 microM) produced an approximate 50% decrease in ICl, but had no effect on the PKA-ICa. Surprisingly, application of DPC (500 microM and 1 mM) and anthracene-9-carboxylate (500 microM) strongly reduced both currents. However, inhibition of the Ca2+ and Cl- channels by DPC could be differentiated in two important ways. First, increasing the pH of the external solution from 7.4 to 10.0 prevented the block of ICl by DPC, but did not attenuate the reduction in the PKA-ICa. Second, DPC inhibited the PKA-ICa in mouse atrial myocytes which lacked ICl. Neither 4,4'dinitrostilbene-2,2'-disulfonic acid (100 microM) nor indanyloxyacetic acid 94 (50 microM) caused any change in either of the guinea pig ventricular currents. CONCLUSIONS: Drugs such as DPC and anthracene-9-carboxylate which block the cardiac CFTR Cl- channel also inhibit the regulation of the L-type ICa. During beta-adrenergic stimulation, changes produced by these drugs on the cardiac action potential duration will be attributable to inhibition of both the Cl- and Ca2+ currents. Analogues of clofibric acid may serve as selective blockers of the CFTR Cl- channel that can be used to determine the physiological function of ICl in cardiac excitation.  相似文献   

3.
02 consumption by human term placenta has been measured during perfusion in vitro, with a technique that permits perfusion of the intervillous space as well as the umbilical circulation. The rate at which 02 was consumed was directly related to the rate at which it was supplied, within the limits studied. Previous estimates of 02 consumption yielded figures approximating 3 ml. per minute per kilogram of placenta, but these estimates were attained under conditions of limited oxygen supply. When oxygen was delivered to the placenta at rates believed to be those achieved in vivo, oxygen consumption approximated 10 ml. per minute per kilogram. This rate of 02 consumption is similar to those obtained from studies of animal placentas in vivo and is more consistent with that of an active metabolic organ. If one were to accept estimates of 02 consumption by the human fetus in utero, the present studies indicate that approximately one fifth of maternal oxygen supplied to the conceptus is diverted to support placental metabolism.  相似文献   

4.
5.
In this article, intraoral intake of an ascending concentration series of sucrose was found to plateau between concentrations of 0.3 M and 2.0 M, and thus failed to show the typical inverted U-shaped intake function found in standard intake tests. Two experiments were conducted to explain this result. In Exp 1, intraoral and standard 30-min, 1-bottle intake of ascending sucrose concentrations (0.03, 0.1, 0.3 1.0, 1.3, and 2.0 M) were compared. Sucrose intake was similar for both delivery methods. In a second experiment we examined the effect of the order of sucrose concentration presentation on the 1-bottle 30-min intake of nondeprived intact rats. An ascending concentration order of the solutions produced a significantly greater intake of concentrated sucrose solutions than did a random order. This result strongly suggests that the standard decline in sucrose intake at higher concentrations is determined not only by postoral factors but also by experiential factors (i.e., order of presentation). (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

6.
The interaction between molten salts of the type LiCl-KCl-MeCl n (Me=Ca, Sr, U; = to 0.45; and x KCl/x LiCl=0.69) and zeolite 4A have been studied at 823 K. The main interactions between these salts and zeolite are molten salt occlusion to form salt-loaded zeolite and ion exchange between the molten salt and salt-loaded zeolite. An irreversible chemical reaction has been observed in the LiCl-KCl-UCl3+zeolite system. The extent of occlusion is a function of the concentration of MeCl n in the zeolite and is equal to 10±1 Cl per zeolite unit cell, (AlSiO4)12, at infinite MeCl n dilution. The ion-exchange mole-fraction equilibrium constants (separation factors) with respect to Li are decreasing functions of the concentration of SrCl2 and UCl3, but an increasing function of the concentration of CaCl2 in the zeolite. At infinite MeCl n dilution, they are equal to 0.9, 11.9, and 13 for CaCl2, SrCl2, and UCl3, respectively. The standard ion-exchange chemical potentials are equal to −50.0, −84, and −101.1 kJ·mol−1 for Ca2+, Sr2+, and U3+, respectively.  相似文献   

7.
The activity of the dissociative anaesthetics ketamine and gamma-hydroxybutyrate against seizures induced by mercaptopropionate and pentylenetetrazol have been determined. Ketamine (90 mg/kg) prevented the seizures induced by both convulsants, but gamma-hydroxybutyrate had negligible anticonvulsant activity. Mercaptopropionate (150 mg/kg) produced a rapid fall in whole brain glutamate decarboxylase activity which correlated with the onset of convulsions. Ketamine given prior to the mercaptopropionate prevented the convulsions, but had no effect on the reduction of enzyme activity. It was concluded that although ketamine was an anticonvulsant it did not act by preventing the inhibition of glutamate decarboxylase responsible for mercaptopropionate-induced convulsions.  相似文献   

8.
A method for reading the foetal heart rate tracings and a guide of management advise in each case have been established from a review of the literature and the study of 500 records. The tracings are schematically divided into three categories according to the presumed risk of foetal distress: normal or "tolerable" tracings, alarm symptoms and danger symptoms. For each categorie, and according to the duration of the variations, a type of management is proposed. Other diagnostic means, such as capillary blood pH measurement are desirable to improve the foetal state diagnostic and make the treatment more precise.  相似文献   

9.
Boneless strip loin subprimals (n = 24) were fabricated from 12 USDA Standard yield grade 2 carcasses at a commercial beef processing facility and processed 48 h postmortem to determine the effect of injection of 200 or 250 mM calcium chloride (CaCl2) solution at 5% (wt/wt) on beef quality traits. One-third of the subprimal served as the control; the remaining portion was injected with either 200 or 250 mM CaCl2 at 5% (wt/wt). The CaCl2 concentration treatment was randomly assigned to strip loins fabricated from either the right or left side of the carcass. After 7 or 14 d of postmortem storage at 2 degrees C, 2.5-cm-thick steaks were cut from each control and treated portion of the subprimals and evaluated for Warner-Bratzler shear (WBS) force, retail display characteristics, Minolta colorimeter L*, a*, and b* values, and trained sensory panel ratings. Treatment of the muscle with 250 mM CaCl2 increased (P < .05) trained sensory panel tenderness and beef flavor scores, and both CaCl2 concentrations decreased WBS force values, when compared with the control. Scores for color, uniformity, and browning in the retail display case did not differ (P > .05) for the 200-mM treatment compared with the control. Scores for discoloration in the retail display decreased (P < .05) for all three-way interactions of CaCl2 concentration, aging time, and display time after d 2 (except 7-d control, which remained the same [P > .05] d 1 through 5). The L* values did not differ (P < .05) for interactions of CaCl2 concentration, x aging time, and retail display.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

10.
工业硅酸浸去除金属杂质钙   总被引:1,自引:0,他引:1  
研究了HF-HCl浸出剂体系中,HF含量、HCl含量、浸出时间和硅粉粒度等因素对除钙的影响.结果表明,HF含量是最主要的影响因素;在2%HF-3%HCl、室温20 ℃、5h的最佳条件下,钙的去除率达到84.5%;在HF-HC1浸出剂体系中,CaF2的形成降低了钙的去除率.电子显微镜和能谱分析发现,工业硅中存在含钙四元系金属间化合物Si8Al6Fe4Ca,该化合物易被低浓度氢氟酸去除.  相似文献   

11.
A hypothesis is presented suggesting that nicotinamide (NIC) is an initial signal substance in the response of eukaryotic cells to conditions which cause DNA-strand breakage, especially in connection with oxidative stress. In the stressed cell, NIC is released as a result of the activity of poly(ADP-ribose)polymerase (PADPRP). PADPRP is known to be activated by DNA-strand breakage, caused by e.g. oxidative stress or mutagens. NIC and its metabolite trigonelline (N-methylnicotinic acid) can induce defensive metabolism at the gene level. Connections between NIC and DNA-methylation are also considered. This hypothesis is discussed in the light of own observations and literature reports.  相似文献   

12.
Spouses' balancing of housework and leisure activities at home may affect their recovery from work. This paper reports on a study of everyday family life in which 30 dual-earner couples were tracked around their homes by researchers who recorded their locations and activities every 10 min. For women, the most frequently pursued activities at home were housework, communication, and leisure; husbands spent the most time in leisure activities, followed by communication and housework. Spouses differed in their total time at home and their proportion of time devoted to leisure and housework activities, with wives observed more often in housework and husbands observed more often in leisure activities. Both wives and husbands who devoted more time to housework had higher levels of evening cortisol and weaker afternoon-to-evening recovery. For wives, husbands' increased housework time also predicted stronger evening cortisol recovery. When both spouses' activities were entered in the same model, leisure predicted husbands' evening cortisol, such that husbands who apportioned more time to leisure, and whose wives apportioned less time to leisure, showed stronger after-work recovery. These results suggest that the division of labor within couples may have implications for physical health. (PsycINFO Database Record (c) 2011 APA, all rights reserved)  相似文献   

13.
14.
Within a prospective study of the course of HIV-infection in women, 80 HIV-infected women without AIDS were delivered of 80 children between 1985 and September 1992. The median of the age of gestation was 38 weeks. Until 1988 Caesarean section was chosen as mode of delivery (45 women). Later when the mode of delivery appeared to have no influence on the frequency of maternofetal HIV transmission, vaginal delivery was preferred (35 women). None of the infants was breastfed. Three infants --delivered vaginally--died within the first 6 months of life before their infection status could be determined. Seventy-seven children could be observed for 18 months or longer regularly every three months. 10 of the 77 children were found to be HIV- infected by serological, virological and clinical criteria. Taking into account the mode of delivery, of 32 children who were delivered vaginally or by emergency Caesarean section 8 were found to be HIV-infected. None of 26 children delivered by elective Caesarean section after an uneventful pregnancy is infected. In 19 women Caesarean section was performed within 2 hours after onset of labour or after episodes of preterm labour which required hospital admission for treatment. Two children of these women are infected. No differences of CD4+ cell counts and p24 antigenaemia could be determined between the mothers of the three groups. The risk of fetal HIV infection was increased by preterm labour (p < 0.01) and the mode of delivery (p < 0.01). A correlation between loss of CD4 cells in the mother and increased risk of infection for the child is seen in children born spontaneously or delivered by emergency Caesarean section (p < 0.001). No correlation was found between the length of labour at delivery, the time of the rupture of membranes before birth as well as of the parity and the risk of fetal infection in that group. These findings point to labour as an important factor which increases the risk of maternofetal transmission of HIV. The onset of labour is accompanied by dramatic immunological alterations as a sudden increase of chemotactics and inflammatory cytokines at the maternofetal interface. The accumulation and stimulation of maternal immune cells will--if these cells are carriers of HIV--result in production and release of infectious HIV. This virus may accumulate in the maternofetal interface or gain access to the amniotic cavity. Since amniotic fluid is swallowed by the fetus, the largest potential port of entry for HIV in the fetus are the fetal lungs and the gastrointestinal tract. For the prevention of maternofetal transmission of HIV delivery before onset of labour or alternatively the protection of the fetus during parturition by means of potent antiviral compounds can be considered.  相似文献   

15.
The oxygen-enriched alpha case on titanium and alloys was successfully deoxygenated to satisfactory levels by electrolysis in molten CaCl2, in which the cathode was made from the metal to be refined. The oxygen distribution in the metal before and after electrolysis was characterized by microhardness tests, scanning electron microscopy (SEM), and energy-dispersive X-ray (EDX). The electrolysis has been carried out at voltages sufficiently below that for the decomposition of CaCl2, and the results obtained suggest that the alpha case deoxygenation follows a simple oxygen ionization mechanism in which the oxygen in the metal is simply ionized at the cathode/electrolyte interface, dissolves in the molten salt, and then discharges at the anode. It is shown that by applying the electrochemical method, the alpha cases on both commercially pure titanium (CP Ti) and the Ti-6Al-4V alloy can be effectively deoxygenated. In particular, due to the removal of oxygen, the original alpha case (single phase) on the Ti-6Al-4V alloy has been converted back to the two-phase microstructure.  相似文献   

16.
A female patient with an ischaemic focal lesion in the non-dominant cerebral hemisphere due to stenosis of the right carotid artery is presented. Besides a mild left hemiparesis the clinical symptomatology included a pronounced hemi-neglect syndrome in the form of unilateral limb akinesia, a failure to respond to stimuli presented to the left of the midline as well as anosognosia and anosodiaphoria. Despite the 6-week rehabilitation training, the neglect syndrome was rather stabilized with only a slight tendency for improvement.  相似文献   

17.
The mechanism by which excessive NaCl intake raises blood pressure has not been fully clarified. The present study was undertaken in 87 Japanese inpatients with essential hypertension to investigate the interrelation among effects of age, sex and the renin-angiotensin system on NaCl sensitivity. After ingesting a regular NaCl diet (170 mmol/day) for one week, subjects were placed sequentially on a week of low NaCl diet (50 mmol/day) and a week of high NaCl diet (340 mmol/day). NaCl sensitivity defined as the difference in mean blood pressure between the low and high NaCl diets did not differ between genders. NaCl sensitivity was positively correlated with age and the change in PRA. The fall in PRA after NaCl loading was significantly smaller in women than in men. By multiple regression analysis, age and the change in PRA independently contributed to the change in mean blood pressure. Furthermore, the interaction between sex and the change in PRA was selected as a statistically significant variable. In conclusion, NaCl sensitivity of blood pressure is independently associated with age and the inadequate suppression of the renin-angiotensin system. Because the contribution of the change in PRA to NaCl sensitivity was greater in women than in men, the mechanism of blood pressure elevation after NaCl loading may differ between genders.  相似文献   

18.
19.
Tested the hypothesis that the amount of time spent watching TV is significantly related to the strength of traditional sex-role development. Data from 80 kindergartners and 2nd, 4th, and 6th graders support the hypothesis and suggest that this relationship holds equally for both sexes and does not change with increasing age. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

20.
Poppy seeds from seven different origins (Dutch, Australian, Hungarian, Spanish, Czech, and two Turkish) were analyzed for the amount of opiates present. Four grams of each kind of seeds, equivalent to the amount of seeds on two bagels, were ingested by volunteers. One volunteer also ingested four times the same amount of poppy seeds from the same origin (Spanish). During 24 hours urine samples were obtained and screened for the presence of morphine and codeine using the FPIA technique (cut-off = 200 ng/mL) and a GC/MS confirmation with a limit of detection (LOD) of 25 ng/mL for codeine and morphine. Poppy seeds from different origins contain a wide variation of morphine (2-251 micro g/g) and codeine (0.4-57.1 micro g/g) content. No other opiate could be detected. After ingestion a large interindividual variation of excretion of opiates exists. The testing results from the same kind of seeds ingested four times with a one week interval by the same volunteer also show a poor reproduceability. Several kinds of poppy seeds can give positive testing results (Australian, Hungarian, Spanish and one kind of Turkish seeds). Within 24 hours all testing results became negative.  相似文献   

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