AUTO-SMASH: A self-calibrating technique for SMASH imaging

Recently a new fast magnetic resonance imaging strategy, SMASH, has been described, which is based on partially parallel imaging with radiofrequency coil arrays. In this paper, an internal sensitivity calibration technique for the SMASH imaging method using self-calibration signals is described. Coil sensitivity information required for SMASH imaging is obtained during the actual scan using correlations between undersampled SMASH signal data and additionally sampled calibration signals with appropriate offsets ink-space. The advantages of this sensitivity reference method are that no extra coil array sensitivity maps have to be acquired and that it provides coil sensitivity information in areas of highly non-uniform spin-density. This auto-calibrating approach can be easily implemented with only a small sacrifice of the overall time savings afforded by SMASH imaging. The results obtained from phantom imaging experiments and from cardiac studies in nine volunteers indicate that the self-calibrating approach is an effective method to increase the potential and the flexibility of rapid imaging with SMASH.     

A multicoil array designed for cardiac SMASH imaging

Recently, several partially parallel acquisition (PPA) techniques have been presented which use spatial information inherent in an RF coil array to reconstruct an image from a reduced set of phase encoding steps. PPAs represent a change in paradigm for the RF coil designer since the focus for arrays to be used with PPAs is to optimize the spatial encoding that is provided by the array. One of the first practical implementations of PPA imaging was demonstrated using the SMASH technique. In this study, we present our results from the construction of the first array designed specifically for cardiac SMASH imaging. Additional design criteria are presented for SMASH arrays that are not considered in conventional array design. Using these design criteria, a four-element array was constructed and then tested in SMASH imaging experiments in the heart. This array has been used in all of our initial cardiac and head SMASH studies with good results.     

Recent advances in image reconstruction, coil sensitivity calibration, and coil array design for SMASH and generalized parallel MRI

Parallel magnetic resonance imaging (MRI) techniques use spatial information from arrays of radiofrequency (RF) detector coils to accelerate imaging. A number of parallel MRI techniques have been described in recent years, and numerous clinical applications are currently being explored. The advent of practical parallel imaging presents various challenges for image reconstruction and RF system design. Recent advances in tailored SiMultaneous Acquisition of Spatial Harmonics (SMASH) image reconstructions are summarized. These advances enable robust SMASH imaging in arbitrary image planes with a wide range of coil array geometries. A generalized formalism is described which may be used to understand the relations between SMASH and SENSE, to derive typical implementations of each as special cases, and to form hybrid techniques combining some of the advantages of both. Accurate knowledge of coil sensitivities is crucial for parallel MRI, and errors in calibration represent one of the most common and the most pernicious sources of error in parallel image reconstructions. As one example, motion of the patient and or the coil array between the sensitivity reference scan and the accelerated acquisition can lead to calibration errors and reconstruction artifacts. Self-calibrating parallel MRI approaches that address this problem by eliminating the need for external sensitivity references are reviewed. The ultimate achievable signal-to-noise ratio (SNR) for parallel MRI studies is closely tied to the geometry and sensitivity patterns of the coil arrays used for spatial encoding. Several parallel imaging array designs that depart from the traditional model of overlapped adjacent loop elements are described. Summary of material presented at the 2001 ISMRM workshop on MRI hardware, Cleveland, OH, USA.     

Recent advances in image reconstruction, coil sensitivity calibration, and coil array design for SMASH and generalized parallel MRI.

Parallel magnetic resonance imaging (MRI) techniques use spatial information from arrays of radiofrequency (RF) detector coils to accelerate imaging. A number of parallel MRI techniques have been described in recent years, and numerous clinical applications are currently being explored. The advent of practical parallel imaging presents various challenges for image reconstruction and RF system design. Recent advances in tailored SiMultaneous Acquisition of Spatial Harmonics (SMASH) image reconstructions are summarized. These advances enable robust SMASH imaging in arbitrary image planes with a wide range of coil array geometries. A generalized formalism is described which may be used to understand the relations between SMASH and SENSE, to derive typical implementations of each as special cases, and to form hybrid techniques combining some of the advantages of both. Accurate knowledge of coil sensitivities is crucial for parallel MRI, and errors in calibration represent one of the most common and the most pernicious sources of error in parallel image reconstructions. As one example, motion of the patient and/or the coil array between the sensitivity reference scan and the accelerated acquisition can lead to calibration errors and reconstruction artifacts. Self-calibrating parallel MRI approaches that address this problem by eliminating the need for external sensitivity references are reviewed. The ultimate achievable signal-to-noise ratio (SNR) for parallel MRI studies is closely tied to the geometry and sensitivity patterns of the coil arrays used for spatial encoding. Several parallel imaging array designs that depart from the traditional model of overlapped adjacent loop elements are described.     

An 8-channel Tx/Rx dipole array combined with 16 Rx loops for high-resolution functional cardiac imaging at 7 T

Objective

To demonstrate imaging performance for cardiac MR imaging at 7 T using a coil array of 8 transmit/receive dipole antennas and 16 receive loops.

Materials and methods

An 8-channel dipole array was extended by adding 16 receive-only loops. Average power constraints were determined by electromagnetic simulations. Cine imaging was performed on eight healthy subjects. Geometrical factor (g-factor) maps were calculated to assess acceleration performance. Signal-to-noise ratio (SNR)-scaled images were reconstructed for different combinations of receive channels, to demonstrate the SNR benefits of combining loops and dipoles.

Results

The overall image quality of the cardiac functional images was rated a 2.6 on a 4-point scale by two experienced radiologists. Imaging results at different acceleration factors demonstrate that acceleration factors up to 6 could be obtained while keeping the average g-factor below 1.27. SNR maps demonstrate that combining loops and dipoles provides a more than 50% enhancement of the SNR in the heart, compared to a situation where only loops or dipoles are used.

Conclusion

This work demonstrates the performance of a combined loop/dipole array for cardiac imaging at 7 T. With this array, acceleration factors of 6 are possible without increasing the average g-factor in the heart beyond 1.27. Combining loops and dipoles in receive mode enhances the SNR compared to receiving with loops or dipoles only.

     

Investigation of complex phased array coil designs for cardiac imaging

In this study we present a method to simulate complex phased array coil designs for cardiac imaging. It is based on the combination of numerically calculatedB ₁ field vectors for each coil of the array and a noise resistance data set, which is acquired only once with a set of test coils. This technique allowed fast assessment of the SNR performance of arbitrary geometries of single coils to be used as building blocks in complex array configurations. In addition, since clinical scanners usually provide only four receiver channels, we used this method to investigate the use of hardware combiners for different array configurations, consisting of up to eight coils. Simulated array geometries resulted in up to ≈30% gain in SNR for deep cardiac structures, compared to a conventional linear four coil array. This was confirmed by phantom experiments with implemented coils     

Phase compensation in single echo acquisition imaging

Parallel imaging in magnetic resonance imaging is currently the primary route to decreasing scan time. Single echo acquisition (SEA) imaging is a completely parallel imaging method that collects a full image in a single echo. This article discusses the implications related to imaging with voxel-sized coils, specifically as they relate to the potential for SEA imaging with large planar and cylindrical arrays. Phased array coils with large numbers of elements have been used to form images in SEA imaging. As implemented, the array elements are on the order of the voxel dimensions in one direction. A complication that arises in this case is the potential for signal loss due to the phase variation over the voxel impressed by the receive coil. This problem has been investigated for the cases of planar and cylindrical arrays. In the case of planar arrays, a single phase compensation pulse can be shown to easily eliminate the dephasing of the radio frequency (RF) coil. Unfortunately, for cylindrical arrays, the rotation of the coil phase gradient requires different phase compensation gradient strengths to optimize the signal from each coil, an obvious problem in single echo imaging. One potential solution is to use the cylindrical coil in the transmit/receive mode, which eliminates the need for phase compensation entirely but will require a more complex interface to the scanner.     

Accelerated time-resolved 3D contrast-enhanced MR angiography at 3T: clinical experience in 31 patients

Purpose: To evaluate whether time-resolved 3D MR-angiography at 3T with a net acceleration factor of eight is applicable in clinical routine and to evaluate whether good image quality and a low artifact level can be achieved with a temporal update rate that allows for additional information on pathologies. Materials and methods: Thirty-one consecutive patients underwent time-resolved 3D contrast-enhanced MR-angiography on a 3T system. Imaging consisted of accelerated 3D gradient echo sequences combining parallel imaging with an acceleration factor of four, partial Fourier acquisition along phase and slice encoding direction, and twofold temporal acceleration using view sharing. Data volumes representing the arterial and venous contrast phases were independently evaluated by two experienced radiologists by grading of image quality and artifact level on a 0–3 scale. Results: Time-resolved MR-angiography was successfully performed in all subjects without the need for contrast agent bolus timing. Excellent arterial (average score = 2.65 ± 0.32) and good venous (average score = 2.56 ± 0.28) diagnostic image quality and little image degrading due to artifacts (average score = 2.20 ± 0.16) were confirmed by both independent readers (agreement in 65.2% of all evaluations). In 14 patients vascular pathologies were identified in the arterial phases. In eight examinations temporal resolution and depiction of contrast agent dynamics provided additional information about pathology. Discussion: Without the necessity for additional bolus timing, time-resolved 3D contrast-enhanced MR-angiography with imaging acceleration along both the spatial encoding direction and temporal domain revealed excellent diagnostic image quality in neurovascular and thoracic imaging. Despite the limited spatial resolution as compared to high-resolution imaging of the carotid artery bifurcation, the results demonstrate the applicability of contrast-enhanced MR-angiography in thoracic and abdominal MRA as well as cervical imaging with a temporal update rate allowing for additional information on pathologies. Future studies may include an evaluation of optimal trade-offs between spatial and temporal resolution, different acceleration factors and a comparison to the gold-standard for accuracy.     

A degeneracy study in the circulant and bordered-circulant approach to birdcage and planar coils

A method for finding closed-form solutions for the normal mode frequencies of systems with circulant 2pi/2 symmetry was investigated. This method is particularly good for questions of degeneracy that arise when one considers parallel imaging techniques like SENSE and SMASH in MRI. It is applicable to systems that include birdcage coils as well as planar coils with the appropriate rotational symmetry. A proof is given that complete degeneracy of all normal mode frequencies is impossible when all mutual inductive couplings are included. We tested the method against measurements made on a planar coil array and on an 8-element birdcage coil. The inclusion of the co-rotating end-ring mode changes the fundamental symmetry of the system from circulant to "bordered circulant". Closed-form solutions for the normal mode frequencies of a bordered circulant system are also given.     

Multiple channel phased arrays for echo planar imaging

A new interface combining phased arrays and echo-planar imaging (EPI) technologies was developed for two channel breast MR EPI applications. A detailed design for a dual-channel, EPI-compatible, phased array breast coil is described. EPI digital data multiplexing, signal controlling and sampling schemes are also presented. Results from breast phantoms and patients demonstrate a 55% improvement in signal-to-noise ratio when compared to a conventional two-loop, single channel coil configuration. This method can be easily expanded to a four or more channel, EPI-compatible, phased array system to improve field-of-view coverage and signal-to-noise ratio.     

Multiple channel phased arrays for echo planar imaging

A new interface combining phased arrays and echo-planar imaging (EPI) technologies was developed for two channel breast MR EPI applications. A detailed design for a dual-channel. EPI-compatible, phased array breast coil is described. EPI digital data multiplexing, signal controlling and sampling schemes are also presented. Results from breast phantoms and patients demonstrate a 55% improvement in signal-to-noise ratio when compared to a conventional two-loop, single channel coil conliguration. This method can be easily expanded to a four or more channel. EPI-compatible, phased array system to improve field-of-view coverage and signal-to-noise ratio.     

Comparison of three commercially available radio frequency coils for human brain imaging at 3 Tesla

Objective To evaluate a transverse electromagnetic (TEM), a circularly polarized (CP) (birdcage), and a 12-channel phased array head coil at the clinical field strength of B ₀ = 3T in terms of signal-to-noise ratio (SNR), signal homogeneity, and maps of the effective flip angle α. Materials and methods SNR measurements were performed on low flip angle gradient echo images. In addition, flip angle maps were generated for α_nominal = 30° using the double angle method. These evaluation steps were performed on phantom and human brain data acquired with each coil. Moreover, the signal intensity variation was computed for phantom data using five different regions of interest. Results In terms of SNR, the TEM coil performs slightly better than the CP coil, but is second to the smaller 12-channel coil for human data. As expected, both the TEM and the CP coils show superior image intensity homogeneity than the 12-channel coil, and achieve larger mean effective flip angles than the combination of body and 12-channel coil with reduced radio frequency power deposition. Conclusion At 3T the benefits of TEM coil design over conventional lumped element(s) coil design start to emerge, though the phased array coil retains an advantage with respect to SNR performance.     

Design and fabriacation of a three-axis multilayer gradient coil for magnetic resonance microscopy of mice

There is great interest in the non-destructive capabilities of magnetic resonance microscopy for studying murine models of both disease and normal function; however, these studies place extreme demands on the MR hardware, most notably the gradient field system. We designed, using constrained current minimum inductance methods. and fabricated a complete, unshielded three-axis gradient coil set that utilizes interleaved, multilayer axes to achieve maximum gradient strengths of over 2000 mT m⁻¹ in rise times of less than 50 μs with an inner coil diameter of 5 cm. The coil was wire-wound using a rectangular wire that minimizes the deposited power for a given gradient efficiency. Water cooling was also incorporated into the coil to assist in thermal management. The duty cycle for the most extreme cases of single shot echo planar imaging (EPI) is limited by the thermal response and expressions for maximum rates of image collection are given for burst and continuous modes of operation. The final coil is capable of the collection of single shot EPI images with 6 mm field of view and 94 μm isotropic voxels at imaging rates exceeding 50 s⁻¹.     

A degeneracy study in the circulant and bordered-circulant approach to birdcage and planar coils

A method for finding closed-form solutions for the normal mode frequencies of systems with circulant symmetry was investigated. This method is particularly useful for questions of degeneracy that arise when one considers parallel imaging techniques like SENSE and SMASH in MRI. It is applicable to systems that include birdcage coils as well as planar coils with the appropriate rotational symmetry. A proof is given that complete degeneracy of all normal mode frequencies is impossible when all mutual inductive couplings are included. We tested the method against measurements made on a planar coil array and on an 8-element birdcage coil. The inclusion of the co-rotating end-ring mode changes the fundamental symmetry of the system from circulant to 'bordered circulant.' Closed-form solutions for the normal mode frequencies of a bordered circulant system are also given.     

Design and optimization of a 3‐coil resonance‐based wireless power transfer system for biomedical implants

This paper presents a resonance‐based wireless power transfer system using a single layer of inductor coil windings, in a pancake configuration, in order to obtain a compact system for implantable electronic applications. We theoretically analyzed the system and characterized it by measuring its inductance, self‐resonant frequency, and quality factor Q. In our resonance‐based wireless power transfer prototype, we proposed a 3‐coil system, using two 15‐mm radius implantable coils, with a resonance frequency of 6.76 MHz. This system can effectively transfer power for a distance of up to 50 mm. Moreover, our proposed 3‐coil system can achieve a high Q‐factor and has a comparable power transfer efficiency (PTE) to previously reported works about 3‐coil and 4‐coil systems. The experimental PTE can achieve 82.4% at a separation distance of 20 mm and more than 10% PTE at a distance of 40 mm. Copyright © 2014 John Wiley & Sons, Ltd.     

基于超声相控线阵的缺陷全聚焦三维成像

在无损检测领域,缺陷三维成像能够还原材料内部缺陷的空间信息,与传统的二维成像相比有着明显的优势。目前实现超声相控阵缺陷三维成像主要依靠面阵探头,而这些设备往往十分复杂和昂贵。通过采取适当的数据采集方法和后处理成像算法,超声相控线阵系统能够实现低成本、高效率的三维超声检测成像。采用断层扫描和全矩阵捕捉的方法获取成像数据;再利用全聚焦成像算法绘制高分辨率的断层图像;根据这些图像在三维空间中真实的位置关系,插值还原出缺陷的三维图像。此外,针对全聚焦成像算法计算量大的问题,提出了一种加速算法。实验表明,这种检测方法能够快速得到目标空间区域的高质量三维图像,准确体现缺陷的空间分布情况,相比于借助B扫查图像和C扫查图像材料内部缺陷的方法,具有更强的直观性。     

基于USB+FPGA技术的密码算法硬件实现平台设计

设计了一种基于USB2．0和现场可编程门阵列（FPGA）技术的密码算法硬件实现平台。讨论了该平台系统架构、各层面划分及其解决方案,使用超高速集成电路硬件描述语言设计了端口复用先入先出阵列存储器、数据加密等功能模块,对平台功能进行了验证。     

Efficient foldover suppression using SENSE

Parallel imaging techniques, which in principle represent procedures of unfolding a reduced dataset, are well known and well established in MR imaging. This paper presents a further application of one particular reconstruction method, the SENSE algorithm, considered from a different point of view to remove potential foldover in conventional images acquired with multiple receive coils. Based on the coil sensitivity information, a body coverage map in the excited plane is calculated. This is used together with the measured raw data in a SENSE-type reconstruction to optimize the signal-to-noise ratio (SNR) as well as to remove foldover reliably by unfolding the image to a larger field of view. The reconstruction is performed automatically, without any user interaction, and does not affect data acquisition. Based on phantom and in vivo studies, which retain high image quality after the removal, the potential and limits of this approach are discussed, also taking into account future scanner hardware that will support a large number of parallel receiver channels.Acknowledgement The authors would like to thank Romhild Hoogeveen from Philips Medical Systems in Best, Netherlands, for helpful discussions.     

Experimental verification of massive antenna systems employing parallelogram planar arrays

This paper experimentally verifies how the parallelogram planar array (PPA) can improve the space division multiplexing (SDM) performance of multiuser massive multiple‐input multiple‐output (MIMO) in line‐of‐sight (LOS) channels. PPA can reduce the spatial channel correlation (inter‐user correlation) without any increase in processing load. Channel state information (CSI) of up to 94 antenna elements is measured with simplified test equipment in an outdoor propagation environment. Assessment of the measured CSI confirms the effectiveness of PPA in terms of reduced spatial channel correlation and its higher order SDM ability with simplified user scheduling.     

遥感云图纹理特征提取算法实时加速设计

为了解决灰度共生矩阵对遥感云图特征提取实时图像处理过程中算法复杂度高,运算时间长,数据运算量大等问题,提出了一种Vivado HLS实现卫星遥感云图特征提取算法的硬件加速方法.通过对灰度共生矩阵纹理特征提取算法以及Vivado HLS硬件加速设计进行研究,利用Vivado HLS对灰度共生矩阵纹理特诊提取进行硬件加速,...