Effect of pulse duration and size of interelectrode interval on electrospark spraying. II. Effect of pulse duration and size of interelectrode interval on composition and mechanical properties of coatings

The effect of electrospark spaying on the hardness, wear resistance, and phase composition of hard-alloy coatings is investigated. A coating mechanism is proposed to consider change in dynamic properties of cathode jets depending on the interelectrode interval and the effect of pulse duration on the local temperature of the substrate. __________ Translated from Poroshkovaya Metallurgiya, Vol. 46, No. 1–2(453), pp. 115–121, 2007.     

Effect of cholecystokinin on meal size and intermeal interval in the sham-feeding rat.

Gave 8 Sprague-Dawley male albino rats with gastric fistulas liquid food with the fistula closed (normal feeding) or open (sham feeding) after 3 hrs of food deprivation. Meal size (MS) was larger, latency to rest (LR) after a meal was longer, and intermeal interval (IMI) was shorter during sham feeding than during normal feeding. The putative satiety signal cholecystokinin (CCK, 20% pure) decreased MS and LR and increased IMI during sham feeding. After CCK (30 U/kg) the MS, LR, and IMI were the same during sham feeding as during normal feeding. The synthetic octapeptide (OCT) of CCK, which has the known biological actions of the complete hormone, reproduced the effects of CCK (30 U/kg) on MS and LR but not on IMI. The CCK and OCT were also tested for their ability to serve as a UCS for the formation of a conditioned taste aversion (CTA) in 10 3-hr food-deprived sham-feeding rats. The OCT did not serve as a UCS for a CTA in the same sham-feeding conditions in which OCT produced normal MS and LR. Impure CCK (30 U/kg), however, did serve as a UCS for a CTA under these conditions. Results are consistent with the hypothesis that CCK produces satiety in rats. (18 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effect of grain size of WC-Co-B alloying electrodes on the formation of a reinforced layer during electric-spark alloying

Conclusions A study was made of the effect of grain. size of electrodes made of a low-cobalt hard metal microalloyed with amorphous boron, on the cathode weight gain, and quality of resultant coatings. With decreasing alloying electrode grain size, the cathode weight gain grows and the coating structure becomes more continuous.Translated from Poroshkovaya Metallurgiya, No. 11(215), pp. 80–83, November, 1980.     

Effect of spraying rate on microstructure of spray deposited Al-Fe-V-Si alloy

Abstract

In this study gas atomisation and spray deposition of a series of AlFeVSi alloys were carried out. Traces of transient liquid were observed as lamellar structure in the middle of the specimen. The heat transfer conditions of this structure were modelled by finite difference calculation. Metallographic specimens for optical microscopy were prepared from the preforms formed in these processes. Optical microscopy showed the presence of dispersoids in the specimens. The dispersoids were characterised as AlFeVSi cubic phase by X-ray diffraction analysis. SEM was used to examine the morphology of phases and quantitative element analysis to reveal the chemical composition of the dispersoids present. The one-dimensional mathematical model, which describes the heat diffusion during spray deposition, was solved using the finite difference method.     

Effect of pulse duration on wound healing using a CO2 laser

Epidemiological data strongly implicate sunlight as the principal environmental cause of melanoma; however, critical molecular targets for ultraviolet (UV)-induced melanoma remain to be identified. The p53 tumor suppressor gene is one possible target, being abnormally expressed in 20-40% of primary melanomas. We undertook a population-based molecular epidemiological study with the aim of determining the environmental and phenotypic factors associated with p53-positive and p53-negative melanomas. One hundred fifty cases of melanoma were randomly ascertained from the Queensland Cancer Registry and matched to 150 electoral roll controls. Data on environmental and phenotypic exposures were collected through interviews and physical examination of all participants. Sections of tumor tissue were obtained from 134 (89%) cases and stained with the anti-p53 DO-7 monoclonal antibody (MAb) following microwave antigen retrieval. Of 121 useable sections, 22 tumors (18%) had more than 1% cells with positive staining consistent with abnormalities in p53 expression. Strongest predictors of p53-positive melanoma were inability to tan [odds ratio (OR) 6.8], history of non-melanoma skin cancer (OR 3.2) and site of melanoma: head/neck (OR 2.2) and lower limbs (OR 2.3). In contrast, factors such as nevus density and freckling propensity were strongly associated only with p53-immunonegative melanoma (OR 8.6 for >25 moles; OR 3.0 for heavy facial freckling). Overall, the determinants of p53-positive and p53-negative melanomas were independent and complementary, the former being associated with features of sun-sensitivity and chronic sun exposure, the latter with phenotypic markers of melanocytic proliferation. Our findings are consistent with at least 2 independent pathways in the pathogenesis of melanoma, characterized by environmental induction and p53 overexpression on the one hand and pigment cell instability on the other.     

Effect of current pulse frequency on the structure and properties of electric-spark alloyed coatings of the Ti - Al - N system

The mass transfer kinetics, composition, structure, and properties of coatings, formed by high-frequency electric-spark alloying of 45 and 40X steels with the Ti - Al (3:1, 1:1, 1:3) intermetallics and TiN - AIN (1:1) nitride were studied as a function of the current pulse frequency(ν = 1200 and 1600 Hz). A decrease in ν was found to lead to a higher mass transfer coefficient and higher microhardness and Young’s modulus of the coating as well. This is due to the decrease in the Ti/Al ratio on the surface. The phase composition of intermetallic and nitride coatings differed only insignificantly and did not depend on the value of ν. The main phases of the coatings were Fe - Ti - O and Al - Ti - O solid solutions. The nitride and intermetallic coatings had similar friction coefficients f and wear rates I (f = 0.26 and 0.28, I = 5.4 and 5.9 µm/km), despite the difference in their structure. We can assume that the coating phase composition which defines the composition of the secondary structure under dry friction, is the main factor controlling tribological behavior.     

Influence of autonomic tone on QT interval duration

The autonomic tone has been shown to influence the duration of the QT interval, however the independent contribution of sympathetic and parasympathetic tone is not fully elucidated. The influence of autonomic tone on QT duration was studied in 10 young healthy volunteers by evaluating the changes in QT and RR duration induced by i.v. isoproterenol infusion and by standing before and after i.v. administration of propranolol or atropine. Furthermore, the relationship between RR interval and QT duration was evaluated during nocturnal sinus arrhythmia and submaximal exercise test. Low doses of isoproterenol reduced RR (p < 0.01) but not QT interval duration, while higher doses influenced both RR (p < 0.0001) and QT (p < 0.001) duration. Propranolol did not influence standing-induced shortening of RR and QT intervals; on the contrary, atropine administration abolished standing-induced QT interval shortening, without influencing RR changes. QT duration resulted significantly related to preceding RR interval at peak exercise (r = 0.87, p < 0.001) and during nocturnal sinus arrhythmia (r = 0.73, p < 0.0005), however, the regression lines showing the correlation between QT and preceding RR interval were different. Both sympathetic and parasympathetic tone appear to contribute to heart rate-independent changes in QT duration. In the basal state parasympathetic more than sympathetic tone influences the relation QT-heart rate. Major increases of sympathetic nervous system activity may change the relation QT-heart rate. Thus, in case of abrupt autonomic changes, any proposed formula for heart rate correction of QT may result inappropriate, also in the normal range of heart rate.     

Peripheral control of meal size in the rat: Effect of sham feeding on meal size and drinking rate.

3 sham-feeding studies using liquid diets and 9 mildly food-deprived male albino Sprague-Dawley rats suggest the existence of 2 types of control signals that determine liquid meal size. One appears to be a signal arising from activation of tension receptors in the stomach wall that set an upper limit on the size of a meal. The other appears to be a signal that controls the rate at which fluid is ingested. This 2nd type of signal may be a form of conditioned control of ingestion because repeated experience with sham feeding leads to progressive increases in the drinking rate. The progressive increase may reflect the extinction of a control signal that normally modulates the rate of fluid ingestion. (24 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Glomerular filtration rate and kidney size after six years disease duration in non-insulin-dependent diabetic subjects

To evaluate the association of TNFB NcoI polymorphism with SLE in the Korean population, we investigated the frequencies of the TNFB and HLADRB1 alleles in 281 controls and 97 SLE patients, including 56 patients with nephritis and 41 patients without nephritis. The frequency of the TNFB*2 homozygote in SLE was significantly increased over controls (43.3% vs 28.5%, RR = 1.9,p < 0.01). In SLE with nephritis, the TNFB*2 homozygote was more significantly increased (57.1% vs 28.5%, RR = 3.4,p < 0.0001), whereas there was no significant difference between SLE without nephritis and controls. The study of HLA-DRB 1 alleles revealed the increased frequencies of DRB1*02 and *03 (30.9% vs 18.2%, RR = 2.0,p < 0.01; 8.2% vs 2.1%, RR = 4.1,p < 0.05). There was no significantly different distribution of HLA-DRB1 alleles between SLE patients with nephritis and without nephritis. We found positive LD between TNFB*1 and HLA-DR1B1*13, and between TNFB*2 and the particular DRB1 allele: *15, *04, and *07 in controls and/or in SLE patients. After stratification for each HLADRB1 allele, SLE with nephritis showed a higher frequency of TNFB*2 homozygote compared with the corresponding controls in DRB1*15, *08, and *09 positives. Our results suggest that the TNFB*2 homozygote may be a strong susceptibility gene of SLE with nephritis in the Korean population.     

Effect of grain size on high strain rate deformation of copper

Experiments were performed to observe the deformation characteristics of oxygen-free high-conductivity (OFHC) copper at high strain rates (up to 40,000 s⁻¹) and to relate differenc in grain size with differences in deformation behavior. The rod impact and torsional Hopkinson bar test methods were used in these experiments. Results show that grain size reductions substantially reduce surface irregularities that develop during deformation. The effect of grain size on the yield stress and on the strain-hardening behavior of copper is small and is similar to the effect of grain size in copper at quasistatic strain rates. The observation that grain size has a substantial effect on surface irregularities may have important implications for applications in which stable deformation of thin sections is of concern.     

Effect of electrode (tool) material density on the electric-spark alloying process

Conclusions Determinations were made of the effect of sintering temperature on density, hardness, and transverse rupture strength for VK6 and T30K4 hard metals. The relationship was found between the increase in volume of the layer forming on the cathode base plate and the starting porosity of a hard-metal alloying electrode. It is shown that a residual porosity of hard metals of 7–9% ensures optimum conditions of coating formation in the ESA of steel.Translated from Poroshkovaya Metallurgiya, No. 7(223), pp. 53–55, July, 1981.     

WC粉末粒度对超音速火焰喷涂WC-CoCr涂层组织性能的影响

采用超音速火焰喷涂(HVOF)工艺制备了纳米结构、双峰结构和常规结构3种WC-CoCr复合涂层。探讨了不同WC粉末粒度对涂层沉积过程的脱碳行为、涂层微观组织及力学性能的影响。结果表明:随WC颗粒尺寸减小,涂层脱碳率增大,W_2C含量增加,孔隙率降低,涂层的显微硬度和界面结合强度增大;但是纳米结构涂层中粘结相的非晶化现象严重,断裂韧度显著下降;双峰结构涂层因纳米、亚微米WC颗粒的合理搭配和协同效应表现出最好的断裂韧性,同时兼具较高的显微硬度和界面结合强度。     

Effects of dose and interdose interval on conditioned heart rate tolerance to smoking.

The effects of an environmental cue and smoking administration on heart rate (HR) responses to smoking were investigated in 2 studies. The 1st study was performed without smoking, to rule out the possibility that the cue manipulations alone could produce HR habituation. Thirty-six male nonsmokers were exposed to 6 trials of a changing or repeating cue (segments of a story on audiotape), followed by a paced-breathing period. HR habituation was not found. In the 2nd study, 40 male smokers smoked 4 puffs every 10 min (small-dose/long-interdose interval [IDI]) or 6 puffs every 5 min (large-dose/short-IDI) in 6 trials. The same repeating or changing cue preceded smoking. Only the repeating-cue, small-dose/long-IDI group developed HR tolerance. Modifying the cue on Trial 6 did not reverse tolerance. The results indicated that (a) tolerance to smoking appears to be subject to conditioning, (b) this effect depends on the dose and IDI, and (c) the observed tolerance is not likely to be a result of the effects of the cue alone. Nonassociative tolerance to smoking a high-dose/short-IDI did not occur in this study. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Wheel access duration in rats: I. Effects on feeding and running.

The effects of 0-, 2-, and 24-hr wheel access on the pattern of running, feeding, and weight were explored over 24 days in 3 groups of 8 male rats. Both 2 and 24 hr of wheel access suppressed feeding by about 15% for about 8 days before feeding gradually returned to normal. Weight in these 2 groups was similar and was suppressed for the 24 days. Like the pattern seen with drug self-administration (S. H. Ahmed & G. F. Koob, 1998, 1999), running levels stayed low with short, 2-hr daytime wheel access, but with long, 24-hr access, rats' running escalated over days to chronically high levels. These results may have relevance for the understanding of addiction and anorexia nervosa. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

ERPs in anterior and posterior regions associated with duration and size discriminations.

The main objective of the present study was to determine whether event-related potentials (ERPs) predominant in prefrontal cortex (PFC) respond in a similar fashion to ERPs predominant in posterior parietal cortex (PPC) in duration and size discrimination tasks. The results indicate that contingent negative variation (CNV) and P300 components changed according to task demands. In the time-related task, amplitudes and duration of both components increased as a function of stimulus duration and easier discriminability. This was not the case in the size discrimination task. These results are in accordance with the hypothesis of a functional link between PFC and PPC in timing behavior. The later-appearing LPCt component was observed in both tasks, but its amplitude increased only as a function of stimulus duration. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Pattern rate and interpattern interval in development of matching simple auditory-visual patterns.

Assessed the possibility that previous failures to find evidence of more rapid inter- than intramodal development of matching of simple auditory and visual patterns have occurred because of the exclusive use of slow patterns and short interpattern intervals. In Exp I 32 1st- and 32 3rd-grade boys were compared in inter- and intramodal matching of fast or slow spatiotemporal patterns with long or short interpattern intervals. In Exp II the same comparisons were made for 32 2nd- and 32 4th-grade boys using temporal patterns. In both studies modality was a within-Ss variable, whereas age, pattern rate, and interpattern interval were between-Ss variables. Results indicate that in Exp I 3 separate indices of sensitivity coincided in indicating a significant effect of pattern rate but not of interpattern interval. The more rapid development of inter- than of intramodal matching for fast but not for slow patterns provided support for the hypothesis that auditory–visual integration increases with age at least in boys. In Exp II there was no indication of differential inter- and intramodal development under any condition. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The effect of abdominal wall morphology on ultrasonic pulse distortion. Part I. Measurements

The relative importance of the fat and muscle layers of the human abdominal wall in producing ultrasonic wavefront distortion was assessed by means of direct measurements. Specimens employed included six whole abdominal wall specimens and twelve partial specimens obtained by dividing each whole specimen into a fat and a muscle layer. In the measurement technique employed, a hemispheric transducer transmitted a 3.75-MHz ultrasonic pulse through a tissue section. The received wavefront was measured by a linear array translated in the elevation direction to synthesize a two-dimensional aperture. Insertion loss was also measured at various locations on each specimen. Differences in arrival time and energy level between the measured waveforms and computed references that account for geometric delay and spreading were calculated. After correction for the effects of geometry, the received waveforms were synthetically focused. The characteristics of the distortion produced by each specimen and the quality of the resulting focus were analyzed and compared. The measurements show that muscle produces greater arrival time distortion than fat while fat produces greater energy level distortion than muscle, but that the distortion produced by the entire abdominal wall is not equivalent to a simple combination of distortion effects produced by the layers. The results also indicate that both fat and muscle layers contribute significantly to the distortion of ultrasonic beams by the abdominal wall. However, the spatial characteristics of the distortion produced by fat and muscle layers differ substantially. Distortion produced by muscle layers, as well as focal images aberrated by muscle layers, show considerable anisotropy associated with muscle fiber orientation. Distortion produced by fat layers shows smaller-scale, granular structure associated with scattering from the septa surrounding individual fat lobules. Thick layers of fat may be expected to cause poor image quality due to both scattering and bulk absorption effects, while thick muscle layers may be expected to cause focus aberration due to large arrival time fluctuations. Correction of aberrated focuses using time-shift compensation shows more complete correction for muscle sections than for fat sections, so that correction methods based on phase screen models may be more appropriate for muscle layers than for fat layers.