乙丙橡胶中试聚合工艺物料平衡关系

乙丙橡胶中试溶液聚合工艺是聚合反应气相与脱气系统气相汇总形成循环物流,循环物流中丙烯的组成是聚合物结构的主导因素,丙烯的相变是聚合反应温度的控制关键,因此,明确聚合、脱气、压缩环节丙烯的含量和状态,是物料衡算、热量衡算、动量衡算的关键因素,更是设备设计、工程控制的决定性因素。本文通过根据乙丙橡胶聚合工艺特点,明确聚合釜气液相乙烯、丙烯的物料分配原则,结合聚合反应热换热关系,通过对丙烯循环量、溶解量的计算,确定了聚合工艺物料状态及衡算关系。     

润滑油清净剂烷基苯磺酸碳数分布的LC-MS分析

目前国内外有关润滑油清净剂烷基结构分析主要集中在烷基碳数在C16以下的苯磺酸盐产品,对于C20左右的碳数分布的研究较少。由于润滑油清净剂在色谱分析中的溶解度较低,笔者采用酸化萃取等方法对烷基苯磺酸钙进行前处理,优化了酸化的温度、时间和萃取试剂的用量。利用高效液相色谱-质谱联用技术建立了烷基苯磺酸同系物的检测方法。采用C18反相柱为分析柱,对分离后的各组分用液相色谱-质谱联用(LC-MS)仪进行了确认。得到最佳的色谱分离条件为:流动相为甲醇-水与甲醇-35 mmol/L磷酸二氢钠水溶液,采用梯度洗脱,检测波长为254 nm。结果表明,该法对烷基链为C17~C20的烷基苯磺酸钠的同系物能完全分离。     

利用高分溶解平衡核算加氢装置物料平衡的探索

针对目前实验室测定装置物料平衡方法中存在的高分各种低分子烃类溶解度不同对物料平衡的影响,改变测定装置物料平衡的流程,利用反应物料在高分溶解后废氢中低分子烃类含量,结合HYSYS软件中Adjust功能,较为准确核算装置物料平衡,还原加氢反应本身的反应结果。     

玻璃纤维生产中的产量计算和物料平衡

玻璃纤维由原料到制品的生产过程,是各种材料在不断消耗和添加的过程.生产过程中各个工序、各个阶段的产品对于下道工序,下道阶段又成原料,它们之间的消耗和添加又都对最终制品的产量和质量发生影响.     

物料平衡控制在丙烯精馏塔中的应用

基于物料平衡控制理论及方法,建立稳态模型,并采用动态补偿,前馈控制方法,以SPECTROM系统实现其过程控制,使丙烯合格率由原来的95.4％提高到99.9％。     

常压水煤气部分甲烷化物料平衡和能量平衡计算模型

本文闸明了常压水煤气部分甲烷化物料平衡和能量平衡计算模型。提出了于基物料平衡计算公式。讨论了工业甲烷化催化剂基本参数和干基收缩比的计算方法。分析了甲烷化热效率的构成。     

烷基苯磺酸颜色的探讨

从原料组成、副反应、工艺条件等诸多方面探讨了烷基苯磺酸颜色变深的原因。     

物料平衡管理的优化与创新

阐述了物料平衡管理的优化与创新的内涵及主要做法.并介绍了实施效果.     

反应网络的物料平衡一致性校验

通过对反应网络的物料平衡分析,提出了反应网络的物料平衡一致性校验方程,并用于反应网络的数据校正和推测。     

重烷基苯磺酸的品质改善研究

采用硅胶吸附法和碳酸钡中和法,脱除重烷基苯磺酸（HABSA）中的硫酸。以石油醚和乙醇为洗脱剂,采用硅胶层析柱法洗脱分离HABSA与重烷基苯（HAB）。实验结果表明：硅胶吸附法虽然能脱除一定量的硫酸,但其HABSA回收效果差;与之相反,碳酸钡中和法可脱除70%以上的硫酸,且保持高的HABSA回收率。实验结果也表明,硅胶柱层析法是一种快速简便且高效的分析或工业分离HAB与HABSA的方法。碳酸钡中和法和硅胶柱层析法的联合运用可有效脱除HABSA中的杂质,达到品质改善的目的。     

烟用香精香料中奎尼酸的测定

建立以高效液相色谱测定烟用香精香料中奎尼酸含量的方法。以质量分数50%的乙醇为萃取剂,样品经振荡提取后,采用C18色谱柱分离和二极管阵列检测器测定。结果表明,奎尼酸在1.0～250.0 mg/L范围内线性关系良好,相关系数为0.999,检出限为3.12μg/g,加标回收率为92.6%～105.1%,相对标准偏差（RSD）〈5%（n=5）。所建立的方法具有灵敏度高、准确性好、操作简便等优点,适合于烟用香精香料中奎尼酸的批量测定。     

重烷基苯磺酸的生产,性能及应用

叙述了重烷基苯磺酸在国产ＳＯ３磺化装置上的生产过程中的工艺控制条件和产品的性能,并对其在各工业领域中的应用作了介绍。     

四氟苯甲酸反相高效液相色谱法分离条件的探索

研究了含氟有机酸的高效液相色谱分析方法,应用反相C18色谱柱,以15%甲醇/85%(20mmol/L KH2PO4缓冲溶液pH=2.3)为流动相,流速为1.0mL/min,紫外检测波长276nm。探索了流动相的选择,并考察了此方法的线性关系,回归方程及相对标准偏差,实验表明,在选定色谱条件下,此方法能较好地解决四氟苯甲酸的定量分析问题。     

Development of a Rapid Ultra High-Performance Liquid Chromatography/Tandem Mass Spectrometry Method for the Analysis of sn-1 and sn-2 Lysophosphatidic Acid Regioisomers in Mouse Plasma

Lysophosphatidic acids (lysoPtdOH) are involved in several physiological processes including cell proliferation, inflammation, and glucose metabolism. However, measuring lysoPtdOH is challenging due to inadequate extraction techniques, poor chromatographic resolution, or the inability to discriminate between sn-1 and sn-2 regioisomers. In the present work, we developed a high-throughput (10 min run times) ultra-high-performance liquid chromatography–tandem mass spectrometry method capable of discriminating lysoPtdOH species by their fatty acyl composition and sn-localization on glycerol backbones. We quantitated sn-1/sn-2 regioisomeric pairs of lysoPtdOH with 16:0, 18:0, 18:1, 18:2, 20:4, and 22:6 fatty acyl chains using 50 μL of mouse plasma. The method presented here can be expanded to profile more lysoPtdOH species, and has the potential to be used in clinical settings to quickly screen lysoPtdOH profiles. Finally, the ability to discriminate between sn-1 and sn-2 isomers can provide insights regarding the metabolic origins and fates of specific lysoPtdOH molecules.     

Chromatographic performance of monodisperse macroporous particles produced by modified seeded polymerization. II. The effect of the diluent/seed‐latex ratio

Poly(styrene‐co‐divinylbenzene)‐based monodisperse macroporous particles were obtained by a modified seeded polymerization technique. The monodisperse polystyrene particles, obtained by dispersion polymerization in sufficiently large sizes and with suitable average molecular weights, were directly used as the seed latex in the production of macroporous particles. Therefore, the number of swelling and polymerization stages in the multistage production was reduced. In the first stage, the seed particles were swollen with a diluent, dibutyl phthalate (DBP), and then with a monomer phase including styrene, divinylbenzene, and, as an initiator, benzoyl peroxide. The monodisperse macroporous particles were obtained by the repolymerization of the monomer mixture in the seed particles. The particles, having different porosity characteristics, were synthesized through variations in the dibutyl phthalate/seed‐latex (DBP/SL) ratio. Selected macroporous particle samples were slurry‐packed into stainless steel high‐performance liquid chromatography columns (300 mm long × 7.8‐mm i.d.). The separation of the protein mixture by these columns in the reversed‐phase chromatography (RPC) mode was investigated. Liquid chromatograms with high resolutions were obtained under an acetonitrile/water gradient over a wide range of flow rates (i.e., 0.5–3 mL/min), especially for the particles produced with a monomer/seed‐latex (M/SL) ratio of 3.0 mL/g. In the RPC experiments, the particles produced with an M/SL ratio of 3.0 mL/g and DBP/SL ratios of 1.0 and 1.5 mL/g exhibited better chromatographic performance than the other samples. The maximum theoretical plate number was 3500 for the particles produced with the M/SL ratio of 3.0 mL/g and DBP/SL ratio of 1.5 mL/g with albumin as the analyte. The size exclusion chromatography (SEC) calibration curves and the back‐pressure/flow‐rate relationships of the produced columns were also determined. The particles obtained with an M/SL ratio of 3.0 mL/g and a DBP/SL ratio of 1.5 mL/g exhibited the best performance in SEC applications. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 92: 3685–3696, 2004     

基于高分辨质谱技术的植物源性药食同源特色农产品中10种农药残留的测定和快速筛查

建立了人参、五味子、刺五加、人参花、灵芝和灵芝孢子粉基质中10种农药残留的高分辨液相质谱检测及筛查方法,样品中残留的农药采用乙腈提取,经氯化钠及乙酸钠盐析分层,提取液经无水硫酸镁、N-丙基乙二胺(PSA)和石墨化炭黑(GCB)吸附剂分散固相萃取净化,用高效液相色谱-高分辨质谱定性.在上述检测方法条件下,所测的10种农药...     

高效液相色谱法测定化妆品中依克多因的含量

建立高效液相色谱法测定化妆品中依克多因的分析方法,采用Agilent Poroshell 120 EC-C₁₈色谱柱（100 mm×3.0 mm,2.7μm）分离,以甲醇和p H为3.0的40 mmol/L磷酸二氢钠-10 mmol/L 1-庚烷磺酸钠缓冲溶液梯度洗脱,流速0.8 m L/min,柱温30℃,检测波长210 nm。采用外标法定量测定化妆品中的依克多因含量。结果表明,依克多因在5～800 mg/L的质量浓度范围内呈现良好线性关系,相关系数为0.999 8,方法的检出限和定量限分别为0.3和1.0 mg/L。该方法具有分离效率高、分析时间短、节省溶剂等优点,解决了依克多因在C₁₈色谱柱上保留弱的问题。     

白酒接触塑料中增塑剂迁移规律研究

建立了高效液相色谱法测定增塑剂DBP和DEHP的含量的方法。色谱柱为ZORBAX Eclipse XDB-C184.6×150 mm5μm,以甲醇/水为流动相,紫外检测器外标法定量。方法检出限为2 ng,回收率范围85.6%~113.5%,相对标准偏差为3.4%。结果表明,几种白酒接触塑料在乙醇溶液中增塑剂DBP和DEHP有不同程度的的迁移。其迁移量与提取时间、乙醇浓度、塑料材质等相关。     

国产磺酸生产现状及其质量分析

综述了烷基苯 (LAB)质量与磺酸质量的对应关系 ,特别是LAB的可磺化值对磺酸有效物含量的影响 ,阐述了磺化装置与洗衣粉装置配套的优点。通过国内一些厂家磺酸质量的对比 ,分析了影响磺酸质量及磺酸物料平衡的几个因素 ,并指出了我国目前磺酸生产的实际水平及发展趋势