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Positron emission tomography and nuclear magnetic resonance spectroscopy are non-invasive techniques that allow serial metabolic measurements to be obtained in a single subject. Significant advantages could be obtained if both types of scans could be acquired with a single machine. A small-scale PET scanner, designed to operate in a high magnetic field, was therefore constructed and inserted into the top half of a 7.3 cm bore, 9.4 T NMR magnet and its performance characterized. The magnetic field did not significantly affect either the sensitivity (approximately 3 kcps/MBq) or the spatial resolution (2.0 mm full width at half maximum, measured using a 0.25 mm diameter line source) of the scanner. However, the presence of the PET scanner resulted in a small decrease in field homogeneity. The first, simultaneous 31P NMR spectra (200, 80 degrees pulses collected at 6 s intervals) and PET images (transverse, mid-ventricular slices at the level of the mitral value) from isolated, perfused rat hearts were acquired using a specially designed NMR probe inserted into the bottom half of the magnet. The PET images were of excellent quality, enabling the left ventricular wall and interventricular septum to be clearly seen. In conclusion, we have demonstrated the simultaneous acquisition of PET and NMR data from perfused rat hearts; we believe that the combination of these two powerful techniques has tremendous potential in both the laboratory and the clinic.  相似文献   

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OBJECTIVE: The aim of the study was to investigate the prevalence and demographic correlates of suicidal ideation and behaviours among university students in Australia and the utilisation of mental health services by this population. METHOD: Suicidal ideation and behaviours and demographic variables were assessed in a population of 1,678 undergraduate students by use of a modified Suicide Ideation Scale (SIS) and questionnaire. RESULTS: Sixty two percent of students surveyed showed some suicidal ideation and 6.6% reported one or more suicide attempts. Over half of the group who reported suicide attempts did not use any type of mental health services. Suicidal ideation was found to be highly correlated with previous use of mental health services. In examining the relationship between suicidal ideation (SI) and demographic variables, SI was not significantly different for gender or parental marital status but was related to living arrangements, racial groups, religious affiliation and father's education. CONCLUSIONS: The results suggest that a higher proportion of students reported suicidal ideation and behaviours than that documented in related studies undertaken in the USA. While these findings draw attention to a higher level of suicidal ideation in students who utilise mental health assistance, more than half of those who reported suicide attempts did not use any kind of mental health service. The study has particular implications for detecting and assisting young people with a high suicide risk within the university environment.  相似文献   

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Compares demographic and methodological differences between 2 self-report studies on the prevalence of drug addiction among North American University students. A far higher prevalence of addiction was reported among students at a university in Wisconsin (D. R. Cook; see record 1988-26796-001) than among students at a university in British Columbia, Canada (B. K. Alexander, 1985; B. K. Alexander and A. R. Schweighofer, 1988). It is concluded that the Wisconsin procedure inflated the prevalence data by not ensuring that the Ss defined addiction consistently and by imposing a dichotomous choice on the continuous dimension of addictive involvement. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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A range of health behaviors was related to beliefs concerning health practices and health knowledge. A questionnaire dealing with health-related practices, health beliefs and knowledge of health risk factors was answered by 166 male and 179 female students aged 18-30 years at Stockholm University. Female students reported engaging in better health behavior than males. Beliefs about the importance of health behaviors were closely related to their frequency of occurrence. There was only a weak relationship between health behaviors and knowledge of specific health matters. It is concluded that health attitudes rather than health knowledge determine health behavior.  相似文献   

7.
Examined the academic performance, majors, study habits, and socioemotional adjustment of 177 Chinese and Chinese-American university students. 94 Ss were foreign born, and 83 Ss were 2nd-, 3rd-, or 4th-generation Americans. Data were collected through official university records, questionnaires, and inventories. Ss were divided into 3 groups, depending on place of birth and length of residency in the US. Results indicate that the image of the high-achieving, well-adjusted Chinese student was tempered when criteria other than grade point average were examined. Although grades received by the 3 groups of Ss exceeded the university average, recent immigrants apparently used certain strategies to compensate for limited English proficiency by taking reduced courseloads, studying more hours, and limiting career majors. There was also evidence that the recent immigrants were less socioemotionally adjusted than were other Ss. Implications for counseling and research are discussed. (24 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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Researchers find that most children from divorced families function normally, but some clinicians assert that young people are disturbed even many years after a divorce. These accounts may be less discrepant than they appear, because research typically focuses on notably problematic behavior (disorder), whereas case studies emphasize more subtle inner turmoil (distress). In Study 1 college students reported painful feelings, beliefs, and memories about their parents divorce on a reliable new measure, but they also reported accepting the divorce and having few psychological symptoms. Distress about family life was greater among students from divorced than from married families. Study 2 replicated these findings in a community sample of young people from low-income divorced families. In both studies, greater distress was associated with children's residence, frequency of contact with fathers, interparental conflict, and psychological symptoms. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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This article describes gender differences in alcohol and other drug (AOD) use and misuse in a representative sample of young women and men in the United States. Data were drawn from the National Longitudinal Survey of Youth (NLSY) and focus on gender differences in prevalence and patterns of AOD use in African American, Hispanic, and White young adults ages 19 to 24 years old. Findings are summarized and implications for prevention are presented.  相似文献   

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One of the forces generated during skeletal loading is hydrostatic pressure. In the work presented here, the ability of increased pressure to influence recruitment of osteoclasts was evaluated. Murine marrow cultures, with pO2 and pCO2 kept constant, were subjected to either control (1.0 atm) or elevated (1.37 or 2.0 atm) hydrostatic pressure. As compared to control, cultures pressurized for 6 days at 1.37 atm formed less osteoclast-like cells (OCLC) (71 +/- 6% of control, P < 0.0001). A similar degree of inhibition occurred in cultures exposed to pressure during days 2-4 only (62 +/- 6%), while treatment during days 5-7 failed to inhibit the OCLC number relative to control (99 +/- 5%). Delivery of 2.0 atm pressure on days 2-4 generated 52 +/- 4% OCLC compared to control. Since macrophage colony stimulating factor (MCSF)-dependent proliferation of osteoclast precursors occurs during the pressure-sensitive period, semiquantitative RT-PCR for MCSF mRNA was performed after 3 days in 1.37 atm (days 2-4). As compared to controls, pressure caused a decrease in mRNA coding for the membrane bound form of MCSF (71.2 +/- 4% (n = 25, P < or = 0.05), while the MCSF RT-PCR product representing the secreted form showed no consistent change. This lack of response of the soluble MCSF RT-PCR product was expected, as levels of bioassayable MCSF were not altered by pressure. Extrapolating these data to in vivo conditions suggests that load-bearing will inhibit the formation of osteoclasts.  相似文献   

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Generativity is conceived as a configuration of psychosocial features constellated around the goal of providing for the next generation. This study used a stratified random sampling of young (ages 22–27 yrs), midlife (ages 37–42 yrs), and older (ages 67–72 yrs) adults to examine age–cohort differences in 4 generativity features: generative concern, commitments, actions, and narration. Although prevailing views on generativity (e.g., E. H. Erikson, 1963) predict a peak in midlife and decline thereafter, support for this developmental hypothesis was mixed. Midlife Ss scored higher than young and older Ss on concern and actions in a second administration of measures, but not in the first. Generative commitments and narration showed high scores for both midlife and older Ss and relatively low scores for young Ss. Generative concern, assessed with the Loyola Generativity Scale, was positively associated with life satisfaction. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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The present study is a detailed evaluation of age at smoking initiation among university male students in Kuwait based on a random sample of 664 students selected from all students during 1993. The Acturial Life Table analysis revealed that almost one tenth of the students initiated cigarette smoking between ages 16 and 17 with the rate of initiation increasing rapidly thereafter and reaching 30% by age 20 and almost 50% by the time they celebrate their 24th birthday. The most important environmental risk factor positively associated for smoking initiation was observed to be the history of smoking among siblings with a relative risk of 1.4. Compared to students of medicine and engineering, the students of other faculties revealed a higher risk in smoking initiation with an RR = 1.77 for sciences and commerce and 1.61 for other faculties (arts, law, education and Islamic studies). The analysis revealed a rising generation trend in cigarette smoking. There is a need for reduction of this trend among young adults in Kuwait and throughout other countries in the region.  相似文献   

13.
There is evidence that the origin of obstructive lung disease may be traced back to foetal life. The associations between birth characteristics and asthma symptoms were studied in a random population sample of young Norwegian adults. Respiratory symptoms were recorded in a population-based questionnaire survey. The records of all subjects aged 20-24 yrs were linked with the Medical Birth Registry of Norway. Of 868 subjects born in Norway, there were 690 (79%) responders. The associations between asthma symptoms and birth characteristics were analysed by logistic regression, adjusted for possible confounding factors. Asthma symptoms in young adults were inversely associated with birth weight (odds ratio (OR)wheeze=0.82; 95% confidence interval (CI)=0.69-0.96x500 g increase in birth weight(-1))), and after adjustment for gestational age, birth length, parity and maternal age (ORwheeze=0.69; 95% CI=0.50-0.95x500 g increase in birth weight(-1)). The association did not vary according to adult smoking habits or atopic status and remained when premature and low weight births were excluded (ORwheeze=0.73; 95% CI=0.60-0.90x500 g increase in birth weight(-1)). The association was consistent for all asthma symptoms. Adjusted for birth weight, asthma symptoms were further associated with low gestational age, high birth length and low maternal age. In a random sample of young adults, asthma symptoms were strongly associated with low birth weight, an association driven by the full-term births within the normal birth weight range. The findings show that the risk for adult asthma is partly established early in life and suggest that poor intrauterine growth is involved in the aetiology of asthma.  相似文献   

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CONTEXT: Behaviors that result in potential exposure to human immunodeficiency virus (HIV) usually begin in adolescence or young adulthood, but trends in HIV incidence in young people remain unclear. OBJECTIVE: To estimate trends in HIV incidence in teenagers and young adults. DESIGN AND SETTING: Back-calculation of past HIV incidence in persons born between 1960 and 1974 using US national acquired immunodeficiency syndrome (AIDS) incidence data and estimates of the distribution of times between HIV infection and AIDS. MAIN OUTCOME MEASURES: Incidence and prevalence of HIV in 1988 and 1993 in persons aged 20 and 25 years, respectively, in each of those years. RESULTS: As of January 1993, about 22000 men and 11000 women aged 18 to 22 years were living with HIV infection in the United States. Homosexual contact was the leading route of infection among young men. Heterosexual contact was the leading route of infection among young women. The HIV incidence attributed to homosexual contact or injection drug use decreased among persons aged 20 and 25 years between 1988 and 1993, but HIV incidence attributed to heterosexual contact was stable or increasing. Notably, in men aged 20 and 25 years, HIV prevalence declined by about 50% in white men but was relatively stable in black and Hispanic men. In contrast, HIV prevalence in women aged 20 and 25 years rose by 36% and 45%, respectively, because of increasing heterosexual transmission. Overall, HIV prevalence in persons aged 20 and 25 years declined by only 14% between 1988 and 1993. CONCLUSIONS: In young persons, HIV incidence in homosexual men and injection drug users was slowing by 1993; this favorable trend was offset by increasing heterosexual transmission, especially in minorities.  相似文献   

15.
Applied the cyclic-stage model of self-initiated smoking cessation by J. O. Prochaska and C. C. DiClemente (1984) to data on 3,179 young adults (aged 17–21 yrs) to determine the cross-sectional distribution of stages and the frequency and pattern of changes among stages over time. Compared to older adults, the distribution of the stages differed substantially. There were twice as many relapsers and only half as many maintainers among young adults. One-yr changes in stages were examined using a static model that did not take into account the cyclic nature of the change process and a dynamic model that did. Both models, especially the dynamic model, suggested more movement among stages in younger than in older adults. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

16.
Attempted to replicate I. H. Gotlib's (see record 1984-15153-001) finding of a high intercorrelation among various measures of distress (depression, state anxiety, trait anxiety, psychosomatic complaints, and assertiveness) within an undergraduate sample. Results obtained from 134 undergraduates found the Beck Depression Inventory to be highly correlated with the State-Trait Anxiety Inventory—Form Y, the Rathus Assertiveness Schedule, and the Psychosomatic Symptom Checklist, although the assertiveness measure demonstrated some discriminant validity according to a principal-components analysis. A canonical correlation analysis revealed that all 5 measures of distress were significantly related to causal attributions concerning both positive and negative events on the Attributional Style Questionnaire, partially replicating Gotlib's results. (10 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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This article discusses some personal and situational factors which hinder the use of condoms among young single adults ages 18 to 25 years engaged in sexual exchange relationships in a Ghanaian town. Based on focus group discussions and in-depth interviews, this article highlights some key impediments often not adequately discussed in the discourse on condom use but considered vital in any attempt to increase condom use and ultimately reduce HIV transmission. The includes the dilemma facing women who want to use condoms for HIV prevention in premarital sexual exchange relationships (quite different from prostitution) contracted with material gain in mind. Women may face the risk of losing material benefits from sexual exchange relationships if the man is unwilling to use condoms. It is recommended that HIV health educators must increase the involvement of young single adults in exploring these and situational impediments and together design interventions to improve condom use.  相似文献   

18.
This research tested the hypothesis that age differences in both self-efficacy perceptions and problem-solving performance would vary as a function of the ecological relevance of problems to young and older adults. The authors developed novel everyday problem-solving stimuli that were ecologically representative of problems commonly confronted by young adults (young-adult problems), older adults (older adult problems), or both (common problems). Performance on an abstract problem solving task lacking in ecological representativeness (the Tower of Hanoi problem) also was examined. Although young persons had higher self-efficacy beliefs and performance levels on the Tower of Hanoi task problem and the young-adult problems, this pattern reversed in the domain of older adult problems, where the self-efficacy beliefs and performance of older persons exceeded those of the young. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

19.
The authors utilized a modified version of Herek’s (1986, 1993) Sexual Orientation Survey to assess experiences of religiously based prejudice and discrimination reported by conservative Christian students at public (N = 96) and private religious (N = 96) university settings. Apart from hearing more prejudicial verbal comments, participants attending a secular university did not report experiencing higher levels of actual discrimination and prejudice than respondents attending a Christian university, with one exception: being discriminated against by university faculty. Symptoms of depression and anxiety were not related to perceptions of religiously based prejudice among participants. These findings neither support claims of widespread prejudice against conservative Christian students at secular universities nor permit the complete dismissal of such concerns, particularly among university faculty. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

20.
Although researchers have found that social support is an effective coping mechanism to deal with stress, there has been little research on gender differences in perceived stress and use of social support. In the present study, 186 undergraduate students from a Maritime university rated the perceived stressfulness of five scenarios, and identified the type and source of social support they would use to cope with each of the situations. Women perceived three of the five scenarios as significantly more stressful than did men. Women indicated that they would turn to their partner and friends to a greater extent than men would. Women also reported that they would seek emotional support to a greater degree than did men. However, when the perceived stressfulness of the scenarios was controlled, some of the gender differences in the sources and types of support disappeared. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

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