共查询到19条相似文献,搜索用时 73 毫秒
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以紫沙参多糖及水提取物作为受试物,观察其连续多次经口给对免疫功能的影响。结果显示能显著地增加粒廓清指数K及吞噬指数α,增强单核巨噬细胞的吞噬功能;能显著增加小鼠耳肿胀度,提示沙参能够增强二硝基氟苯诱导的小鼠迟发型变态反应。 相似文献
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1.通过紫沙参水提物,醇提物经口经给药和腹腔注射给药的最大耐受量试验,结果显示紫沙参水提物和醇提物均属基本无毒范围。2.以紫沙参的乙醇提取物,乙酸乙酯提取物作为受试物,观察其连续多次经口给药的镇咳,祛痰作用,结果显示紫沙参镇咳,祛痰作用显著。 相似文献
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西洋参根多糖对免疫抑制小鼠免疫功能的影响 总被引:7,自引:0,他引:7
应用环磷酰胺引起免疫抑制小鼠模型,观察了西洋参根多糖(PQRP)对其免疫功能的影响。结果表明,PQRP不仅能抗免疫抑制小鼠外周血白细胞减少、胸腺和脾脏重量的减轻,并能增强正常和免疫抑制小鼠网状内皮系统的吞噬功能;可明显促进免疫抑制小鼠牌淋巴细胞转化,并提高白细胞介素-2活性。提示PQRP可作为一种新的免疫调节剂。 相似文献
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《中国生物制品学杂志》2015,(7)
目的探讨枸杞多糖对亚健康小鼠机体免疫功能及抗疲劳作用的影响及其作用机制。方法采用复合因素建立亚健康小鼠模型,随机分为模型组、枸杞多糖高剂量组(400 mg/kg体重)和低剂量组(200 mg/kg体重),另设对照组(未建模),经小鼠灌胃给药,每天1次,灌胃21 d,对照组和模型组给予等量蒸馏水。对建模小鼠进行行为学评价;检测各组小鼠的免疫功能(脾脏和胸腺指数、T和B淋巴细胞增殖能力及CD4+/CD8+值)和抗疲劳能力(游泳力竭时间、下丘脑5-羟色胺(5-hydroxytryptamine,5-HT)和多巴胺(Dopamine,DA)含量及海马区谷氨酸受体NR2A m RNA表达水平)。结果模型小鼠体重、自主活动次数、挣扎时间及游泳力竭时间明显低于对照组(P0.05),避暗穿梭次数明显高于对照组(P0.05)。模型组小鼠的胸腺、脾脏指数、B淋巴细胞增殖能力、CD4+/CD8+值、游泳力竭时间、下丘脑DA含量及海马区NR2Am RNA的表达均显著低于对照组(P0.05),5-HT含量明显高于对照组(P0.05);枸杞多糖高剂量组小鼠胸腺指数、脾脏指数、B淋巴细胞增殖能力、CD4+/CD8+值、游泳力竭时间、下丘脑DA含量及小鼠海马NR2A m RNA的表达均显著高于模型组(P0.05),且5-HT含量明显低于模型组(P0.05);各组间T细胞增殖能力无明显变化。结论成功建立亚健康小鼠模型,枸杞多糖可提高亚健康模型小鼠的免疫功能及抗疲劳作用,为枸杞多糖的临床应用提供了实验依据。 相似文献
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《化工之友》2008,(11)
目的研究具有潜在益生特性的乳酸杆菌Lactobacillus casei.Zhang(LcZhang活)菌、灭活菌制剂对小鼠免疫功能的影响,为进一步研究其增强机体免疫活性的机理提供依据。方法采用动物活体试验方法,应用分离自酸马奶,并经过耐酸性实验、人工胃肠消化液中存活能力筛选的LcZhang,制备成热致死菌体和活菌制剂各分成高、中、低三个剂量组灌服小鼠15d,测定胸腺指数、脾脏指数;观察ConA促进脾淋巴细胞增殖作用、脾脏巨噬细胞吞噬中性红的能力。结果与对照组相比,实验各组的胸腺指数无明显变化。活菌制剂组脾脏指数、脾淋巴细胞增殖能力、脾巨噬细胞吞噬中性红的能力有所提高且差异显著(P<0.05);并且在本试验选取的3个剂量范围内基本呈量效关系。灭活菌制剂对以上指标的影响与对照相比无显著差异。结论LcZhang活菌制剂的免疫调节作用优于热致死菌体制剂。活菌制剂对小鼠的非特异性免疫功能及细胞免疫功能产生了多方面的、有利于机体免疫功能状态的调节作用。 相似文献
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为研究颜料紫1的脱色问题,从一盒长满菌苔的广告浓缩染料(主要显色原料颜料紫1)中筛选菌株,通过摇瓶培养、以及平板分离等获得了单一纯种菌株、并进一步对该菌株进行了18S rDNA测序分析,从而鉴定出该菌为杂色曲霉(Aspergillus versicolor).在此基础上,系统地研究了该菌株对颜料紫1的脱色条件.综合单因素实验和响应面法优化实验的结果表明:该杂色曲霉菌对于颜料紫1脱色的最佳条件为碳源葡萄糖 30g/L,颜料紫1起始含量为250 mg/L,NaNO3含量为0.3g/L,pH 值5.5,这时可获得最高的颜料紫1脱色率为84.64%.最后,通过傅里叶变换红外光谱仪(FTIR)分析,揭示了该杂色曲霉菌对颜料紫1的脱色机制主要为吸附脱色. 相似文献
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熔块釉中外加氧化锌的作用及对铅,镉溶出量影响的应用研究 总被引:1,自引:0,他引:1
本文研究了熔块釉中外加氧化锌的作用及不同类型的氧化锌对铅、镉溶出量的影响,并指出用间接法氧化锌(BA01-05(I型)优级品)代替直接法氧化锌(ZnO-X1),对降低陶瓷铅镉溶出量,使其达到美国FDA准则要求有比较理想的效果。 相似文献
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A study of the dry-pressing characteristics of several fire brick and building brick clays was made by compressing them, at high and low pressures, into large shapes with a hydraulic press The clays do not effectively transmit the pressure into the interior. The finest grained clays are morc deficient in this respect. The result is a porosity gradient as high as 15% of the interior porosity between center and surface. Such a variation may account, in part, for the defects in dry-press ware. The addition of fired grog increases the pressure transmission. Some clays require more than 50% grog and some less for maximum pressure transmission and optimum results. Fireclay shapes as much as ten inches in thickness and of substantially uniform physical properties can be formed if the proper amount of grog is used. 相似文献
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Of the three factors, elasticity, coefficient of expansion and rate of temperature change, which affect spalling, the former is by far the most important. Only small differences are found between fire clay mixtures of widely varying structure and composition in the rate at which they change in temperature under like conditions of heating. The coefficient of expansion varies directly with the silica content and differences in this respect of large order were found. However, the spalling on the particular mixtures tested varied almost inversely as the coefficient of expansion. This apparent discrepancy is explained on the basis of greater elastic properties of the brick which had high expansions. The elasticity may be varied between wide limits and is sufficiently important as to overbalance the effect of greater expansion. This property is accordingly the one upon which efforts directed toward the development of non-spalling brick should be centered. It was discovered that a plastic deformation could be obtained at as low a temperature as 635°C. This gives the effect of elasticity and undoubtedly has considerable influence on spalling at the higher temperature ranges. Results are given for a number of load tests which show clearly the importance of hard firing. The secondary expansion of brick made from Pennsylvania flint clay is shown to be influenced by the temperature of reheating, as well as its rate. Detailed results showing the effect of grind and firing on the finished size of the brick included in the investigation are also given. 相似文献
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煤化程度和升温速率对热分解影响的研究 总被引:24,自引:0,他引:24
采用非等温热重法考察了我国八种煤的热解过程。研究表明,煤热解过程分为三个阶段,其中第二阶段为热解的主要区间,温度范围为250℃ ̄320℃,占总失重的70% ̄80%,随煤化程度的提高,初始热解温度从300℃增加到460℃,随升温速率的提高,热重积分曲线向高温区偏移,煤样热解的最大失重速率温度随之提高,最终失重是由煤化程度和热解的终温决定,升温速率对其没有影响。 相似文献
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The scale-up effect, which is a key factor controlling the performance of industrial cyclones, is conventionally estimated through grade efficienty curves. A new principle based on the centrifugal separation factor (CSF) is proposed to improve the scale-up procedure in designing industrial cyclones. 相似文献
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