共查询到20条相似文献，搜索用时 46 毫秒
1.
Jennifer K. Mooi Michael T.M. Wang Joevy Lim Andreas Müller Jennifer P. Craig 《Contact lens & anterior eye》2017,40(3):170-174
Purpose
To compare clinical tear film break-up time measurements obtained non-invasively, with those measured following minimal and conventional volumes of fluorescein instillation.Methods
Forty-one subjects (20 male, 21 female, mean ± SD age 34 ± 11 years), with or without dry eye, participated in a prospective cross-over study. Tear film break-up time was measured by the Tearscope Plus? with fine grid insert. Measurements were made in triplicate, with no fluorescein instillation (NIBUT), then following application of a minimal volume of 1 μl fluorescein from the Dry Eye Test? (mTBUT), and finally with 15–30 μl of fluid instilled via a conventional fluorescein strip (TBUT). A fifteen-minute interval between each set of measurements minimised the risk of residual contamination effects.Results
All three techniques displayed statistically significant pairwise correlation (all p < 0.001). TBUT values were significantly shorter than both NIBUT (geometric mean 8.6 s versus 10.9s, p = 0.03) and mTBUT (geometric mean 8.6 s versus 10.6s, p = 0.03), and demonstrated narrower spread (both p < 0.05). No significant differences were detected between NIBUT and mTBUT (all p > 0.05).Conclusions
Tear film break-up time values measured with conventional fluorescein instillation were shortened, while minimal fluorescein instillation and non-invasive methods produced comparable readings. This suggests that minimising instilled volumes can reduce the impact of fluorescein on clinical measurements of tear film stability. 相似文献2.
G. Carracedo J. Canales P. Gonzalez A. Recchioni C. Carpena-Torres J. Carballo-Álvarez 《Contact lens & anterior eye》2018,41(2):180-186
Objective
To study the influence of soft contact lens (SCL) central thickness and material in keratoconus on visual function after intracorneal ring segment (ICRS) surgery.Methods
A pilot, experimental, prospective, cross-sectional and double-blind study was performed. Fourteen keratoconus patients with age range of 34.75 ± 9.22 years (7 males and 7 females) with ICRS implanted were involved in the study. Two different SCL materials [Hioxifilcon A (G-5X/p-GMA/HEMA) and Lucifilcon A (silicone-hydrogel)] with four different central thicknesses (0.1, 0.2, 0.3 and 0.4 mm) were fitted in one eye per patient, selected randomly. High and low corrected distance visual acuity (CDVA) and contrast sensitivity (CS), corneal topography and corneal and total aberrometry were measured.Results
Corneal spherical like, coma like and root mean square (RMS) decreased significantly for 0.3 and 0.4 mm in both SCL materials (p < 0.05). Total RMS decreased significantly for 0.4 mm with both SCL materials (p < 0.05). High and low CDVA improved for 0.4 mm of thickness for both materials (p < 0.05). Statistically increasing were found in all thicknesses studied for CS in both materials (p < 0.05).Conclusion
A central thickness of the SCL equal or superior to 0.4 mm seems to decrease the ocular high order aberration (HOA) and to improve the visual function in keratoconus patients implanted with ICRS. However, the modulus of rigidity of the SCL would not influence the HOA correction. 相似文献3.
Purpose
To assess the repeatability and reproducibility of Visante? OCT and Oculus Pentacam HR® in measuring central (CCT) and topographic corneal thickness (TCT) along the principle meridians in keratoconus (KC) corneae.Method
Twenty participants diagnosed with KC were recruited. There were two study visits. On the first study visit, two repeated corneal thickness measurements were obtained with each instrument. Measurements were repeated at least 48hrs later in the same order. TCT were recorded in the 90, 180, 45 and 135 meridians at 1mm intervals across 8mm chord.Results
Mean CCT for Visante? OCT was 484.97 ± 43.14 μm (range: 484.84–486.09) and Oculus Pentacam HR® was 478.86 ± 45.31 μm (range: 477.20–480.53). No significant difference in TCT between the two visits (p = 0.54) and measurements (p = 0.63) for Visante? OCT. For Oculus Pentacam HR®, no significant difference was found for each visit (p = 0.18) but differences existed in the measurements outside of the central region (p = 0.001). Tukey post-hoc analysis shows the differences (p ? 0.05) were found in the +1 and +4 (supero-temporal) locations in the 135 meridian. Significant differences were found comparing the two instruments, (p < 0.05). Bland Altman plots were used to demonstrate the differences between the two instruments and indicate their limits of agreement.Conclusion
Both instruments gave repeatable measurements as no significant differences were found in most locations in all meridians. Comparing the two instruments, they were not reproducible in all locations. 相似文献4.
Michael J. Doughty 《Contact lens & anterior eye》2017,40(2):109-115
Purpose
To assess if polymegethism and pleomorphism were evident in corneal endothelium after medium-term rigid gas permeable (RGP) contact lens wear.Methods
In a cross-sectional observational study over 12 years, single images of the central region of the corneal endothelium of one eye of 46 subjects were taken with a non-contact specular microscope, along with a measure of central corneal thickness (CCT). The images were printed onto A3-sized paper and 100 cells/image measured by planimetry.Results
Subjects aged between 20 and 32 years, with an average cumulative RGP wear of 6.0 +/? 1.6 years (range 3–9 years) were assessed; 26 of the subjects were Caucasian and 20 were Asian. The mean CCT was 0.515 +/? 0.027 mm. The group cell area value was 401 +/? 42 sq micron to give an estimated endothelial cell density (ECD) of 2520 +/? 273 cells/sq mm. As compared to a historical database, most endothelia (37/46) showed some changes with the mean coefficient of variation on cell area (COV) being 36.7 +/? 8.0% and the percentage of 6-sided (HEX) being 51.8 +/? 8.8%. There were modest correlations between years of RGP wear and both COV (p = 0.009, r spearman = 0.424) and HEX (p = 0.025, r spearman = ?0.291), but not for ECD or CCT.Conclusions
Corneal endothelial polymegethism appears to be a commonplace consequence of RGP lens wear with the magnitude of the change being related to the cumulative duration of the lens wear. 相似文献5.
Purpose
To compare the prophylactic efficacy of single application of lipid and non-lipid containing tear supplements, prior to exposure of symptomatic dry eye subjects to a simulated adverse environment.Methods
Thirty subjects with mild-to-moderate dry eye symptoms participated in the prospective, randomised, double-masked, paired-eye trial. A lipomimetic drop (Systane® Balance) was applied to one eye (randomised), and a non-lipid containing drop (Systane® Ultra) applied simultaneously to the contralateral eye. Subjects were subsequently exposed to a validated simulated adverse environment model created by a standing fan directed towards the eye, at a distance of 1 m, for 2.5 min. Low contrast glare acuity, lipid layer grade (LLG), non-invasive tear break-up time (NIBUT), temperature variation factor (TVF), and tear meniscus height (TMH) were evaluated at baseline, following eye drop instillation and following simulated adverse environment exposure.Results
Both therapies resulted in increased NIBUT (both p < 0.001), and prevented its decline below baseline with simulated adverse environment exposure (both p > 0.05). However, only the lipomimetic drop increased LLG (p < 0.001) and precluded its fall below baseline post-adverse environment exposure (p = 0.15). Furthermore, post-instillation and post-exposure LLGs and NIBUT were significantly higher in the lipomimetic group (all p < 0.05). No significant changes were observed in glare acuity, TVF and TMH (all p > 0.05). More subjects (67%) reported greater ocular comfort in the eye receiving the lipomimetic.Conclusions
Single application of both lipid and non-lipid containing eye drops conferred protective effects against exposure to adverse environmental conditions in subjects with mild-to-moderate dry eye, although the lipomimetic demonstrated superior prophylactic efficacy. 相似文献6.
Sarah La Porta Weber Rossen Mihaylov Hazarbassanov Alex Nasaré José Álvaro Pereira Gomes Ana Luisa Hofling-Lima 《Contact lens & anterior eye》2017,40(3):151-156
Purpose
To evaluate conjunctival impression cytology and HLADR expression changes after wearing scleral contact lenses (ScCLs) for moderate to severe dry eye disease (DED).Design
Prospective interventional case series.Methods
Forty-one eyes from 25 patients with moderate to severe DED were evaluated for Esclera ScCL treatment. Best-corrected visual acuity (BCVA) and slit-lamp findings were assessed. Impression cytology specimens were obtained from DED patients at the baseline and after wearing ScCLs for 12 months. The impression cytology specimens were analyzed using morphological results score, and HLA-DR positive cells were detected and quantified. The values were compared to assess the IC changes after wearing ScCLs.Results
Forty-one eyes from 25 patients were fitted with ScCLs to manage DED. The underlying diseases were Stevens-Johnson syndrome (22 eyes), Sjogren’s syndrome (11 eyes), graft-versus-host disease (2 eyes), dry eye after keratomileusis (2 eyes) and undifferentiated ocular surface disease (4 eyes). The HE-PAS impression cytology score did not differ significantly before and after wearing ScCLs for 12 months in DED patients (p > 0.05). The percentage of eyes expressing the HLA-DR antigen in the temporal conjunctiva after wearing ScCL for 12 months significantly increased in patients with Sjogren’s syndrome (11.11% to 66.66%; p = 0.0498). In groups with Stevens Johnson syndrome and other ocular surface disorders, we did not observe statistically significant differences (p > 0.05).Conclusions
The ScCLs did not change the parameters used to evaluate inflammatory processes, which were measured using conjunctival impression cytology and HLA-DR expression, except in Sjogren syndrome, in which there was an unexpected increase in HLA expression. 相似文献7.
Purpose
To compare the current optometric practices and attitudes in the management of keratoconus patients in the UK and Spain.Methods
An online survey (adapted to optometric practices) was distributed via a newsletter emailed by various professional organizations in the UK and Spain.Results
Four hundred and sixty-four practitioners (126 in the UK; 338 in Spain) who prescribed gas permeable GP contact lenses (CLs) more than once per month (54.8% of UK practitioners and 28.1% of practitioners in Spain; p < 0.01) responded to the questionnaire. A combination of multiple factors is considered necessary in the keratoconus detection (79.4% in the UK, 75% in Spain; p = 0.68), and the use of classification criteria is considered relevant (67.5% in the UK, 70.7% in Spain; p = 0.49). There is a high consensus on the consideration that GP CL fitting is more difficult in keratoconus (79.4% in the UK, 80.5% in Spain; p = 0.79) requiring more diagnostic lenses (3.2 ± 1.4 and 3.4 ± 1.2 in the UK and Spain, respectively; p = 0.72) than are necessary for healthy eyes. Using corneal topography is uncommon from both countries (38.1% in the UK, 59.8% in Spain; p < 0.01), with a similar ophthalmologist referral pattern (at initial diagnosis, 50% in both the UK and Spain; p = 1.00). Few cases of co-management with ophthalmologists were noted (no co-management reported by 60.3% in the UK and 72.8% in Spain, p = 0.01).Conclusion
This study provides initial observations and evidence regarding keratoconus management by optometrists in the UK and Spain and shows similarity in the professional practices and attitudes of practitioners in these two countries. 相似文献8.
Izabela K. Garaszczuk Maryam Mousavi Alejandro Cervino Exposito Maciej M. Bartuzel Robert Montes-Micó D. Robert Iskander 《Contact lens & anterior eye》2018,41(1):54-59
Purpose
To assess the early-phase of tear clearance rate (TCR) with anterior segment optical coherence tomography (OCT) and to determine the association between TCR and other clinical measures of the tear film in a group of young subjects with different levels of tear film quality.Methods
TCR was classified as the percentage decrease of subject’s inferior tear meniscus height 30 s after instillation of 5 μl 0.9% saline solution. Fifty subjects (32F and 18M) aged (mean ± standard deviation) 25.5 ± 4.3 years volunteered for the study. It consisted of a review of medical history, Ocular Surface Disease Index (OSDI) questionnaire, tear film osmolarity measurements, slit lamp examination and TCR estimation based on dynamic measurements of the lower tear meniscus with OCT. Estimates of TCR were contrasted against subject age and tear film measures commonly used for dry eye diagnosis, which includes OSDI score, fluorescein tear film break-up time (FBUT), tear meniscus height (TMH), blinking frequency, tear film osmolarity and corneal staining.Results
The group mean TCR was 29 ± 13% and 36 ± 19% respectively after 30 and 60 s margin after saline solution instillation. Statistically significant correlations were found between TCR and FBUT (r2 = 0.319, p < 0.001), blinking frequency (r2 = 0.138, p < 0.01), tear film osmolarity (r2 = 0.133, p < 0.01) and subject’s age (r2 = 0.095, p < 0.05).Conclusions
Anterior segment optical coherence tomography allows following changes of tear meniscus morphology post saline solution instillation and evaluating the TCR. OCT based TCR might be used as additional measure of the lacrimal functional unit. 相似文献9.
Siegfried Wahl Luise Fornoff G. Alex Ochakovski Arne Ohlendorf 《Contact lens & anterior eye》2018,41(2):175-179
Purpose
The study investigated the effect of the design of multifocal contact lenses on the sensitivity to contrast and disability glare.Methods
Contrast sensitivity was measured in 16 young adults (mean age: 25.5 ± 2.5 years) at a distance of 2 m under two conditions: no-glare and glare. Two designs (Center Near and Center Distance) of the Biofinity soft contact lens were used to simulate correction for presbyopes, while a correction with single vision trial lenses and contact lenses acted as controls.Results
The design of the used multifocal contact lenses had a significant influence on the log area under the curve of the contrast sensitivity function (AUC-CSF). Compared to the spectacle lens correction, the AUC-CSF was significantly reduced, in case CS was measured with the Center Near design lens, under the no-glare (p < 0.001) and the glare condition (p: p < 0.001). In case of the Center Distance design contact lens, the AUC-CSF was significantly smaller in case CS was tested under glare (p = 0.001). Disability glare (DG) was depending on the spatial frequency and the design of the multifocal lens, while the Center Distance design produced higher amounts of DG (p < 0.001), compared to the other used corrections.Conclusion
The optical design of a multifocal contact lenses has a significant impact on the contrast sensitivity as well as the disability glare. In order to dispense the best correction in terms of contact lenses, the sensitivity to contrast under no-glare and glare conditions should be tested a medium spatial frequencies. 相似文献10.
Michael T.M. Wang Irene Cho Soo Hee Jung Jennifer P. Craig 《Contact lens & anterior eye》2017,40(4):236-241
Purpose
To compare the effects on tear film parameters and contamination in cosmetic eyeliner wearers, after single application of two lipid-based dry eye treatments: a lipid-containing lubricant eye drop and a phospholipid liposomal spray.Methods
Fifty participants were enrolled in a prospective, randomised, paired-eye, investigator-masked trial. Pencil eyeliner (Body Shop® Crayon Eye Definer) was applied to the upper eyelid periocular skin of both eyes, anterior to the lash line. Baseline tear film quality was assessed fifteen minutes after eyeliner application. A lubricant drop (Systane® Balance) was then applied to one eye (randomised), and liposomal spray (Tears Again®) to the contralateral eye. Tear film contamination, lipid layer grade, non-invasive tear film break-up time and tear evaporation rate were evaluated fifteen minutes post-treatment and compared to pre-treatment values.Results
Pre-treatment measurements did not differ between eyes assigned to lubricant drop and liposomal spray. Tear film contamination was observed in a greater proportion of eyes following both treatments (both p < 0.05), with no significant difference between treatments (p = 0.41). Both treatments improved lipid layer thickness (both p ≤ 0.01), but effected no significant change in non-invasive tear film break-up time or tear evaporation rate (all p > 0.05). Changes in tear film parameters did not differ between treatments (all p > 0.05).Conclusions
Both the lipid-containing lubricant eye drop and phospholipid liposomal spray result in clinically apparent tear film contamination in eyeliner cosmetic wearers. Although both treatments effected an increase in lipid layer thickness, neither displayed clinical efficacy in improving tear film stability. 相似文献11.
Maria Vidal-Rohr James S. Wolffsohn Leon N. Davies Alejandro Cerviño 《Contact lens & anterior eye》2018,41(1):117-121
Aim
Retrospective analysis of different contact lens wearing groups suggests lens surface lubricity is the main factor influencing contact lens comfort. However, the examined commercially available contact lenses differ in material and design as well as surface properties. Hence this study isolates the contribution of lens surface properties using an ultra-thin coating technology.Methods
Nineteen habitual contact lens wearers (21.6 ± 1.7years) wore formofilcon B soft monthly disposable contact lenses with and without coating technology modified surface properties for a month each in a randomised double-masked cross-over study.Objective non-invasive
breakup time (NIKBUT), NIKBUT average and ocular redness (Jenvis grading scale) were evaluated (Keratograph 5M) after 1 week and 1 month of wear. Symptoms were assessed using the Contact Lens Dry Eye Questionnaire (CLDEQ-8); perceived vision quality and subjective lens comfort at insertion, mid-day and end of the day were rated with four Visual Analog Scales.Results
Perceived visual quality (F = 5.049,p = 0.037), contact lens dry eye symptoms (F = 14.408,p = 0.001) and subjective lens comfort (F = 28.447,p < 0.001) were better for coated compared to uncoated lenses. The surface coating postponed the lens dewetting (F = 8.518,p = 0.009) and increased the pre-lens tear film stability (F = 5.626,p = 0.029), but bulbar (F = 0.340,p = 0.567) and limbal (F = 0.110,p = 0.744) redness were similar for both contact lenses. No parameter changed significantly between a weeks’ and months’ wear (p > 0.05). Lens surface wettability and ocular redness were not correlated to changes in symptoms (p > 0.05).Conclusion
As previously hypothesised, enhancing the physical surface properties of a soft contact lens improves subjectively rated wearer comfort, which, in turn, should result in reduced contact lens discontinuation. 相似文献12.
Purpose
To assess dry eye treatment with four preservative-free dry eye artificial tear treatments to facilitate evidence-based prescribing.Methods
A randomised, single masked crossover trial of Clinitas Soothe, Hyabak, Tears Again and TheraTears artificial tears was conducted on 50 symptomatic dry eye patients, aged 60.8 ± 14.2 years. At baseline and after trialling each treatment for 4 weeks, signs and symptoms were assessed using the Ocular Surface Disease Index (OSDI), non-invasive tear break-up time, fluorescein tear break-up time, tear meniscus height (TMH), Phenol Red test, lid-parallel conjunctival folds (LIPCOF), ocular surface staining, and lipid layer grading and osmolarity (baseline visit only).Results
OSDI (p = 0.002), LIPCOF (p = 0.014) and conjunctival staining (p < 0.001) significantly improved from baseline, however, the impact of each dry eye treatment on ocular symptoms and signs was similar. Clinitas Soothe and Hyabak were preferred by 34%/30% of participants, but only subjective comparison with the other drops influenced this choice. TheraTears was preferred (by 24%) by those with a lower baseline tear volume (p = 0.01) and Tears Again (by 12%) by those with a thinner baseline lipid layer (p = 0.04). The treatment that afforded the greatest improvement in clinical signs did not consistently match each individual’s preferred treatment.Conclusions
If prescribed to a general dry eye population, the artificial tears performed similarly, improving symptoms and conjunctival signs. However, osmolarity balanced artificial tears were the preferred treatment in individuals with low baseline tear volume and lipisomal spray for individuals with a baseline lipid layer deficiency. 相似文献13.
Sara Ortiz-Toquero Guadalupe Rodriguez Victoria de Juan Raul Martin 《Contact lens & anterior eye》2017,40(3):143-150
Purpose
To calculate and validate a new web-based algorithm for selecting the back optic zone radius (BOZR) of spherical gas permeable (GP) lens in keratoconus eyes.Methods
A retrospective calculation (n = 35; multiple regression analysis) and a posterior prospective validation (new sample of 50 keratoconus eyes) of a new algorithm to select the BOZR of spherical KAKC design GP lenses (Conoptica) in keratoconus were conducted. BOZR calculated with the new algorithm, manufacturer guidelines and APEX software were compared with the BOZR that was finally prescribed. Number of diagnostic lenses, ordered lenses and visits to achieve optimal fitting were recorded and compared those obtained for a control group [50 healthy eyes fitted with spherical GP (BIAS design; Conoptica)].Results
The new algorithm highly correlated with the final BOZR fitted (r2 = 0.825, p < 0.001). BOZR of the first diagnostic lens using the new algorithm demonstrated lower difference with the final BOZR prescribed (-0.01 ± 0.12 mm, p = 0.65; 58% difference ≤ 0.05 mm) than with the manufacturer guidelines (+0.12 ± 0.22 mm, p < 0.001; 26% difference ≤ 0.05 mm) and APEX software (-0.14 ± 0.16 mm, p = 0.001; 34% difference ≤ 0.05 mm). Close numbers of diagnostic lens (1.6 ± 0.8, 1.3 ± 0.5; p = 0.02), ordered lens (1.4 ± 0.6, 1.1 ± 0.3; P < 0.001), and visits (3.4 ± 0.7, 3.2 ± 0.4; p = 0.08) were required to fit keratoconus and healthy eyes, respectively.Conclusion
This new algorithm (free access at www.calculens.com) improves spherical KAKC GP fitting in keratoconus and can reduce the practitioner and patient chair time to achieve a final acceptable fit in keratoconus. This algorithm reduces differences between keratoconus GP fitting (KAKC design) and standard GP (BIAS design) lenses fitting in healthy eyes. 相似文献14.
Purpose
To investigate the effect of soft contact lenses (SCL) wearing modality and lens materials on the changes in conjunctival bulbar and limbal redness and conjunctival and corneal staining after two months of SCL wear. Comfort level was also analyzed.Methods
In this longitudinal clinical trial, forty-seven neophyte myopic subjects were fitted with a monthly disposable lens (lotrafilcon-B or comfilcon-A or balafilcon-A) in one eye and a daily disposable lens (nelfilcon-A or stenofilcon-A or nesofilcon-A) in the other eye, randomly selected. Conjunctival bulbar and limbal redness and conjunctival and corneal staining were evaluated before and after lens wear. Effect of lens wearing modality and lens materials on these changes was also determined. Level of comfort was evaluated subjectively twice per day. Comfort level and reduction in end-of-day comfort were compared between different lens wearing modalities and materials.Results
Bulbar and limbal redness and conjunctival and corneal staining were increased (p < 0.001) after lens wear, and changes were similar with daily and monthly disposable lens wear (p > 0.05). Limbal redness was associated with lens materials, and lotrafilcon-B induced the least among the studied lenses (p < 0.05). There was no significant association between the wearing modality and the average comfort level and reduction of end-of-day comfort (p > 0.05).Conclusion
Two months of SCL wear increased conjunctival redness, conjunctival and corneal staining, which were not associated with the lens wearing modality. There was a reduction in end-of-day comfort, similar to daily and monthly lenses. The change in limbal redness and reduction in end-of-day comfort were associated with the characteristics of the lens material. 相似文献15.
Purpose
To compare the efficacy of Dr Organic Tea Tree Face Wash, OcuSoft Lids Scrub Plus and the BlephEx? device at treating of Demodex folliculorum blepharitis.Methods
Eighty-six subjects (33 males/36 females) were enrolled in a randomised controlled interventional treatment study. Subjects completed a dry eye symptom questionnaire and were assessed for presence of Demodex folliculorum. Subjects were divided into three groups according to treatment: Dr Organic Tea Tree Face Wash (A) (n = 28), OcuSoft Lid Scrub Plus (B) (n = 30), or in-house lid scrub with the BlephEx? device before nightly lid scrubs with OcuSoft Lid Scrub Plus (C) (n = 28). Subjects were advised to clean their eyelids nightly for four weeks. Each subject was re-assessed for symptoms and Demodex folliculorum blepharitis after two weeks and four weeks of treatment.Results
The quantity of Demodex folliculorum was significantly reduced after four weeks of treatment in all three groups (p < 0.05). Overall, there was no difference in efficacy between the three treatments (p > 0.1). Symptoms reported by subjects were significantly improved after two and four weeks of treatment (p < 0.05). Overall, there was no difference in efficacy between the three treatments to reduce symptoms after two or four weeks (p = ?0.813 and p = 0.646 respectively).Conclusion
All three methods tested have shown good ability to reduce Demodex folliculorum quantity, improve subjective symptoms and help treat Demodex folliculorum blepharitis. 相似文献16.
Kate Gifford Paul Gifford Peter L. Hendicott Katrina L. Schmid 《Contact lens & anterior eye》2017,40(3):184-189
Purpose
To compare near point binocular vision function of young adult myopes wearing orthokeratology (OK) lenses to matched single vision soft disposable contact lens (SCL) wearers.Methods
A retrospective clinical record analysis of all OK wearers (18–30 years) presenting over an 18 month period was undertaken. Data was extracted for 17 OK wearers, with 17 SCL wearers matched for age, refractive error and duration of contact lens wear. Binocular vision data included horizontal phoria (phoria), horizontal base-in (BIFR) and base-out fusional reserves (BOFR) and accommodation accuracy (AA).Results
The OK group was 25.8 ± 3.2 years, with a duration of wear of 45.7 ± 25 months and refractive error of R ?2.09 ± 1.23D, L ?2.00 ± 1.35D. Compared to matched SCL wearers the OK group were significantly more exophoric (OK ?2.05 ± 2.38Δ; SCL 0.00 ± 1.46Δ, p = 0.005) and had better accommodation accuracy (OK 0.97 ± 0.33D; SCL 1.28 ± 0.32D, p = 0.009). BIFR and BOFR were not different in the two groups. Frequency histograms showed that more SCL wearers had high lags of accommodation (AA ≥ 1.50D: 8 SCL,2 OK) and esophoria (≥1Δ: 5 SCL,1 OK) than OK wearers. A positive correlation was found between refraction and phoria in the SCL group (r = 0.521, p = 0.032).Conclusion
Young adult myopes wearing OK lenses display more exophoria and lower accommodative lags at near compared to matched single vision SCL wearers. Young adult myopes with specific binocular vision disorders may benefit from OK wear in comparison to single vision SCL wear. This has relevance to both the visual acceptance of OK lenses and in managing risk factors for myopia progression. 相似文献17.
Michael T.M. Wang Kalaivarny Ganesalingam Chee Seang Loh Trisha Alberquerque Suhaila Al-Kanani Stuti L. Misra Jennifer P. Craig 《Contact lens & anterior eye》2017,40(1):53-58
Purpose
To assess the effects of two weeks of regular phospholipid liposomal spray application on lipid layer grade, tear film stability, subjective comfort, visual acuity, and lipid deposition in silicone hydrogel contact lens wearers.Methods
Thirty-one existing contact lens wearers were enrolled and fitted with two week planned replacement silicone hydrogel contact lenses (Acuvue® Oasys®) in a prospective, randomized, paired-eye, investigator-masked trial. A phospholipid liposomal spray (Tears Again®) was applied to one eye (randomized) four times daily for two weeks. LogMAR high contrast visual acuity (VA), low contrast glare acuity (LCGA), non-invasive tear film break-up time (NIBUT), and lipid layer grade (LLG) were measured at baseline and day 14, in both treated and control eyes. Subjective comfort relative to baseline, and spectrofluorophotometric assessment of contact lens surface lipid deposition were also assessed on day 14.Results
All measurements did not differ at baseline between treated and control eyes. Lipid layer thickness and tear film stability were increased on day 14 in treated eyes (all p < 0.05), but not in control eyes (all p > 0.05). A greater proportion of participants reported improved comfort in the treated eye relative to the control eye (p = 0.002). There were no significant differences in visual acuity or in contact lens surface lipid deposition, between treated and control eyes, on day 14 (all p > 0.05).Conclusion
The phospholipid liposomal spray increased tear film stability, lipid layer thickness and subjective comfort in silicone hydrogel contact lens wearers, without adversely affecting visual acuity or contact lens surface lipid deposition. 相似文献18.
Purpose
To assess the compliance of Daily Disposable Contact Lenses (DDCLs) wearers with replacing lenses at a manufacturer-recommended replacement frequency. To evaluate the ability of two different Health Behavioural Theories (HBT), The Health Belief Model (HBM) and The Theory of Planned Behaviour (TPB), in predicting compliance.Method
A multi-centre survey was conducted using a questionnaire completed anonymously by contact lens wearers during the purchase of DDCLs.Results
Three hundred and fifty-four questionnaires were returned. The survey comprised 58.5% females and 41.5% males (mean age 34 ± 12 years). Twenty-three percent of respondents were non-compliant with manufacturer-recommended replacement frequency (re-using DDCLs at least once). The main reason for re-using DDCLs was “to save money” (35%). Predictions of compliance behaviour (past behaviour or future intentions) on the basis of the two HBT was investigated through logistic regression analysis: both TPB factors (subjective norms and perceived behavioural control) were significant (p < 0.01); HBM was less predictive with only the severity (past behaviour and future intentions) and perceived benefit (only for past behaviour) as significant factors (p < 0.05).Conclusions
Non-compliance with DDCLs replacement is widespread, affecting 1 out of 4 Italian wearers. Results from the TPB model show that the involvement of persons socially close to the wearers (subjective norms) and the improvement of the procedure of behavioural control of daily replacement (behavioural control) are of paramount importance in improving compliance. With reference to the HBM, it is important to warn DDCLs wearers of the severity of a contact-lens-related eye infection, and to underline the possibility of its prevention. 相似文献19.
Does a two-year period of orthokeratology lead to changes in the endothelial morphology of children?
Purpose
To compare changes in endothelial morphology in the central and superior cornea in subjects wearing single-vision spectacles and orthokeratology lenses over two years.Methods
Endothelial images of the two locations of 99 subjects (6–12 years) from completed myopia control studies were analysed. Endothelial cell density (ECD), coefficient of variation in cell size (CV), and hexagonality (HEX) before and two years after treatment were compared between the two groups of subjects.Results
Baseline ECD and CV in the central cornea were slightly lower than those in the superior cornea, but no significant difference in HEX was found in the two corneal locations. After two years, reduction in ECD and increase in CV were only significant in the central cornea, but not in the superior cornea. Reduction in HEX was significant in both corneal locations. Subjects receiving orthokeratology had smaller reduction in ECD in the central cornea compared to the controls (orthokeratology: 56 ± 94 cells/mm2; control: 98 ± 91 cells/mm2, p = 0.024), otherwise, there were no significant differences in the changes in endothelial morphology in the two corneal locations between the two groups of subjects.Conclusions
The current study confirmed that there were differences in endothelial morphology of central and superior cornea of Chinese children aged 6–12 years. The morphological response to normal ageing differed between the two corneal locations as reduction in cell density and polymegathism were found only in the central cornea whilst pleomorphism was found in both locations. Orthokeratology lens wear had minimal effect on the developmental changes in endothelial morphology. 相似文献20.
Melis Palamar Irmak Karaca Huseyin Onay Ilgen Ertam Ayse Yagci 《Contact lens & anterior eye》2018,41(2):154-156