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1.
Purpose
Contact lens discomfort remains poorly understood, not least due to lack of associations between clinical signs and symptoms. This study aimed to explore the relationships between osmolarity, comfort and lid wiper epitheliopathy in contact lens wear.Methods
Twenty subjects participated in a randomized, cross-over study where comfilcon A and lotrafilcon A lenses were each worn for 10 days separated by a 7 days washout period. Tear and contact lens osmolarity, ocular symptoms including comfort, tear stability and production, and lid wiper epitheliopathy were measured.Results
Comfort and tear stability decreased and upper lid wiper staining and foreign body sensation increased with lens wear. These were not affected by lens type. A reduction in tear production was seen after 10 days of comfilcon A lens wear. High proportions of lid wiper epitheliopathy were observed at the upper (range 65%–85%) and lower (range 90%–100%) lid margins. Tear and contact lens osmolarity were unaffected by lens wear or type. Contact lens osmolarity was associated with comfort (r = 0.45, p = 0.009). Tear osmolarity moderately correlated with tear stability (r = ?0.53, p = 0.014) and tear production (r = ?0.44, p = 0.012) but not with lid wiper staining.Conclusions
A relationship between comfort and contact lens osmolarity and between tear osmolarity and tear stability and production were found, however, this study was unable to demonstrate an association between comfort and tear osmolarity or lid wiper epitheliopathy. Further studies using contact lenses with a wider range of comfort responses are warranted to investigate these associations further. 相似文献2.
Luigina Sorbara Jyotsna Maram Trefford Simpson Natalie Hutchings 《Contact lens & anterior eye》2018,41(2):193-200
Purpose
First, to examine how wearing high and low modulus lenses with two different base curves affected lens fit, and the corneal tissue and bulbar conjunctival vascular tissue (bulbar redness and blood velocity). Secondly, to quantify the associations between these baseline and outcome variables and the third purpose was to correlate these variables with end of day comfort.Methods
Thirty participants wore higher (PureVision (PV) 8.3, 8.6) and lower (Acuvue Advance (AA) 8.3, 8.7) modulus silicone hydrogel lenses for two weeks on a daily wear basis. Lens fitting characteristics were examined. Corneal epithelial thickness was measured and the cornea and conjunctiva were assessed. RBC velocity was estimated from high magnification bulbar conjunctival images. Subjective comfort/dryness was reported by participants using visual analogue scales.Results
AA lenses were rated the most comfortable (ANOVA, p = 0.041). The least movement was while using the AA 8.3 base curve lens (Tukey p = 0.028). Steep AA and PV lenses showed significantly higher conjunctival staining at the 2 week visit (ANOVA, p = 0.029). There was a significant decrease in RBC velocity with both steeper AA lenses vs PV lenses (Tukey, p = 0.001). Comparing baseline and 2 week visits, there was a significant negative correlation for the PV 8.3 between comfort and superior bulbar staining (r = ?0.53). For both the PV 8.3 and AA 8.3 reduced RBC velocity was correlated with dryness (r = 0.61 and r = 0.91, respectively).Conclusions
Physical differences in contact lenses affect structural and vascular functional aspects of the ocular surface and these may be associated with symptoms of dryness. 相似文献3.
Purpose
To compare vision correction preferences, refractive error, and gender of non-presbyopes and presbyopes.Methods
Adults who wear spectacles or contact lenses completed a survey about refractive correction opinions and refractive error was measured.Results
Of the 304 subjects, 38.2% were presbyopic (≥40 years) and 59.2% were female. Spectacles were the primary vision correction for 78.0% of subjects. Compared to contact lens wearers, the proportion of presbyopes was higher (p = 0.006) in spectacle wearers. There was no difference in the proportion of presbyopes and non-presbyopes who have tried contact lenses (p = 0.2) or who would prefer to wear contact lenses (p = 0.2). In contact lens wearers, there was no difference in the proportion of presbyopes and non-presbyopes with a history of temporary discontinuation (p = 0.9). Within the contact lens wearing group, there was no refractive error difference between presbyopes and non-presbyopes (spherical equivalent p = 0.6; power vector J0 p = 0.5; power vector J45 p = 0.4; anisometropia p = 0.2). Overall, contact lens wearers were more likely to be female (p = 0.004). There was no difference in gender in presbyopic and non-presbyopic contact lens wearers (p = 0.5).Conclusions
Presbyopes and non-presbyopes have similar opinions about spectacles and contact lenses. Presbyopes of all refractive errors prefer contact lens correction when good vision and comfort can be achieved. Eye care providers should not assume that presbyopia, refractive error, or gender are factors that preclude a patient from being interested in contact lens wear. 相似文献4.
Michael T.M. Wang Kalaivarny Ganesalingam Chee Seang Loh Trisha Alberquerque Suhaila Al-Kanani Stuti L. Misra Jennifer P. Craig 《Contact lens & anterior eye》2017,40(1):53-58
Purpose
To assess the effects of two weeks of regular phospholipid liposomal spray application on lipid layer grade, tear film stability, subjective comfort, visual acuity, and lipid deposition in silicone hydrogel contact lens wearers.Methods
Thirty-one existing contact lens wearers were enrolled and fitted with two week planned replacement silicone hydrogel contact lenses (Acuvue® Oasys®) in a prospective, randomized, paired-eye, investigator-masked trial. A phospholipid liposomal spray (Tears Again®) was applied to one eye (randomized) four times daily for two weeks. LogMAR high contrast visual acuity (VA), low contrast glare acuity (LCGA), non-invasive tear film break-up time (NIBUT), and lipid layer grade (LLG) were measured at baseline and day 14, in both treated and control eyes. Subjective comfort relative to baseline, and spectrofluorophotometric assessment of contact lens surface lipid deposition were also assessed on day 14.Results
All measurements did not differ at baseline between treated and control eyes. Lipid layer thickness and tear film stability were increased on day 14 in treated eyes (all p < 0.05), but not in control eyes (all p > 0.05). A greater proportion of participants reported improved comfort in the treated eye relative to the control eye (p = 0.002). There were no significant differences in visual acuity or in contact lens surface lipid deposition, between treated and control eyes, on day 14 (all p > 0.05).Conclusion
The phospholipid liposomal spray increased tear film stability, lipid layer thickness and subjective comfort in silicone hydrogel contact lens wearers, without adversely affecting visual acuity or contact lens surface lipid deposition. 相似文献5.
Purpose
To investigate the effect of soft contact lenses (SCL) wearing modality and lens materials on the changes in conjunctival bulbar and limbal redness and conjunctival and corneal staining after two months of SCL wear. Comfort level was also analyzed.Methods
In this longitudinal clinical trial, forty-seven neophyte myopic subjects were fitted with a monthly disposable lens (lotrafilcon-B or comfilcon-A or balafilcon-A) in one eye and a daily disposable lens (nelfilcon-A or stenofilcon-A or nesofilcon-A) in the other eye, randomly selected. Conjunctival bulbar and limbal redness and conjunctival and corneal staining were evaluated before and after lens wear. Effect of lens wearing modality and lens materials on these changes was also determined. Level of comfort was evaluated subjectively twice per day. Comfort level and reduction in end-of-day comfort were compared between different lens wearing modalities and materials.Results
Bulbar and limbal redness and conjunctival and corneal staining were increased (p < 0.001) after lens wear, and changes were similar with daily and monthly disposable lens wear (p > 0.05). Limbal redness was associated with lens materials, and lotrafilcon-B induced the least among the studied lenses (p < 0.05). There was no significant association between the wearing modality and the average comfort level and reduction of end-of-day comfort (p > 0.05).Conclusion
Two months of SCL wear increased conjunctival redness, conjunctival and corneal staining, which were not associated with the lens wearing modality. There was a reduction in end-of-day comfort, similar to daily and monthly lenses. The change in limbal redness and reduction in end-of-day comfort were associated with the characteristics of the lens material. 相似文献6.
Purpose
This study was designed to develop a novel technique called non-invasive keratograph dry-up time (NIK-DUT), which used an adapted corneal topographer, to analyse in-vitro contact lens surface dewetting and the effects of combinations of lenses and lens care solutions on dewetting.Methods
Variables were assessed to optimise sensitivity and reproducibility. To validate the method, in-vitro dewetting of silicone hydrogel contact lenses (balafilcon A, comfilcon A, lotrafilcon A, lotrafilcon B and senofilcon A) was tested. All lens types were soaked in OPTI-FREE® PureMoist® Multipurpose Disinfecting Solution (OFPM) and Sensitive Eyes® Saline Solution. The mean NIK-DUT, defined as drying of 25% of the placido ring measurement segments (NIK-DUT_S25), was calculated for each lens/lens solution combination and a visual map constructed representing the time and location of the dry-up event.Results
Optimal conditions for NIK-DUT measurement included mounting onto a glass stage with a surface geometry of r = 8.5 mm, e = 0, and measuring with high intensity red or white illumination. This method detected significant differences in contact lens dewetting with different lens soaking solutions. NIK-DUT_S25 for all lenses was longer when pre-soaked in OFPM versus saline. Visual analysis showed that dewetting of contact lenses was not uniform across surfaces and differed between test solutions.Conclusions
NIK-DUT is suitable for detecting differences in dewetting among various contact lenses and lens-care combinations. NIK-DUT can quantify the dewetting of large areas of lens surfaces with little subjective influence. Lens care solutions containing surface-active wetting agents were found to delay surface dewetting of silicone hydrogel lenses. 相似文献7.
Siegfried Wahl Luise Fornoff G. Alex Ochakovski Arne Ohlendorf 《Contact lens & anterior eye》2018,41(2):175-179
Purpose
The study investigated the effect of the design of multifocal contact lenses on the sensitivity to contrast and disability glare.Methods
Contrast sensitivity was measured in 16 young adults (mean age: 25.5 ± 2.5 years) at a distance of 2 m under two conditions: no-glare and glare. Two designs (Center Near and Center Distance) of the Biofinity soft contact lens were used to simulate correction for presbyopes, while a correction with single vision trial lenses and contact lenses acted as controls.Results
The design of the used multifocal contact lenses had a significant influence on the log area under the curve of the contrast sensitivity function (AUC-CSF). Compared to the spectacle lens correction, the AUC-CSF was significantly reduced, in case CS was measured with the Center Near design lens, under the no-glare (p < 0.001) and the glare condition (p: p < 0.001). In case of the Center Distance design contact lens, the AUC-CSF was significantly smaller in case CS was tested under glare (p = 0.001). Disability glare (DG) was depending on the spatial frequency and the design of the multifocal lens, while the Center Distance design produced higher amounts of DG (p < 0.001), compared to the other used corrections.Conclusion
The optical design of a multifocal contact lenses has a significant impact on the contrast sensitivity as well as the disability glare. In order to dispense the best correction in terms of contact lenses, the sensitivity to contrast under no-glare and glare conditions should be tested a medium spatial frequencies. 相似文献8.
Objectives
To evaluate the corneal confocal microscopy and dry eye findings in patients with contact lens discomfort.Methods
The study included 3 groups of participants: Contact lens wearers using silicone hydrogel soft contact lenses who are symptomatic (CLD, n = 15) or asymptomatic (ACL, n = 11) and non-wearers as controls (n = 14). Duration of contact lens wear, Ocular Surface Disease Index (OSDI) questionnaire responses, fluorescein tear break-uptime (FBUT), and corneal confocal microscopy findings were recorded.Results
Mean age was 25.7 ± 8.2 years and male/female ratio was 7/33. Demographic findings were similar regarding the groups. CLD patients had a longer lens use history than ACL (median 5 vs 2 years, p < 0.001). OSDI scores were higher in CLD group than ACL or controls (p < 0.001, p = 0.002). FBUT was significantly lowest in CLD group, compared to controls and ACL (p < 0.001, p = 0.039). FBUT was also lower in ACL patients compared to controls (p = 0.036). There was no difference between basal epithelium cell counts between all 3 groups. Anterior stromal activated keratocyte numbers were similar between contact lens using groups but was lower in controls (p = 0.005). However, dendritiform cells in the sub-basal nerve layer were higher in CLD group compared to controls but similar to ACL (p < 0.001, p = 0.058). Graded sub-basal nerve tortuosity was more prominent in CLD group than the ACL (p = 0.014).Conclusion
Patients with CLD had been wearing contact lenses for longer than those without symptoms. OSDI and FBUT scores were worse in CLD patients. In contact lens discomfort patients, there were increased dendritiform cells, indicating intensified inflammatory status of the cornea. 相似文献9.
Jennie Diec Thomas Naduvilath Daniel Tilia Eric B. Papas Percy Lazon de la Jara 《Contact lens & anterior eye》2017,40(6):367-381
Purpose
To describe a ranked symptoms scale (RSS) discriminating subjective responses in contact lens (CL) wear in various situations.Method
Forty experienced clinical trial participants were interviewed for their perceptions of ocular comfort scales, resulting in a numerical RSS. For further evaluation, 20 CL wearers enrolled into a prospective, randomised, crossover trial. Two silicone-hydrogel CLs and a lens care solution (LCS) [Combinations A & B] were selected based on prior performance identifying best/worst combinations for end-of-day comfort. The RSS and a numerical rating scale (NRS) were administered at two time-points (insertion/removal) on alternating days for 6 days.Results
Both NRS and RSS showed acceptable internal consistency for comfort, vision and handling (Cronbach alpha = 0.71 for both scales) and similar repeatability for comfort and handling (coefficients-of-repeatability within 0.1 and 0.2 units, respectively, for each scale). The NRS and RSS discriminated differences between combinations for comfort (p ≤ 0.031) and vision (p ≤ 0.026) at both time-points. Additionally, the RSS showed lens/edge awareness influenced discomfort the most, ranking higher at insertion (p = 0.038) and higher for Combination-B at both time-points (p ≤ 0.002). Symptoms of dryness and tired eyes increased for both combinations at removal (p < 0.02). The RSS also showed haziness and blurred distance vision influenced vision dissatisfaction with Combination-B at lens removal (p ≤ 0.038) while eye strain/headache increased for both combinations by time of removal (p ≤ 0.013).Conclusions
The RSS is able to discriminate subjective responses between combinations and time-of-day. The RSS’s ability to rank symptoms may be a useful tool in understanding perceptions of discomfort or dissatisfaction with CL wear. 相似文献10.
Qiurong Zhu Bi Yang Nan Deng Yifan Li Tingwei Wang Huang Qi Longqian Liu 《Contact lens & anterior eye》2018,41(2):229-233
Purpose
To assess the prevalence and general knowledge of contact lens wearers among college students in Chengdu, a metroplolitan of Chinaand find out the routine habits of use and hygienic conditions when wearing contact lenses.Method
The questionnaire was distributed to 1,600 ametropic participants who were from 8 different universities. Data about demographics, general contact lens handling habits, personal attitudes, hygiene behaviors and eye health conditions were collected. We made the analysis ofthe demographics and wearing of contact lenses. Possible reasons for behaviors related to the care of contact lenses were analyzed.Results
The prevalence of contact lens use was 19.80%. Most users (82.15%) were females. An aesthetic effect was cited as the first reason for using (57.91%). The comfort of eyes was the first consideration (75.76%) when buying. To keep clean and use safe, 86.20% subjects washed hands before handling and 83.50% cleaned the lens carefully after removing. There was significant difference between males and females regarding the replacement of the solution (p = 0.014). 32.66% wears knew the removal of protein deposits. A total of 54.88% were not informed of the potential complications of contact lens. The incidence of ocular discomfort was 44.78%. Only 3.03% of the students paid regular visits to ophthalmic clinics.Conclusion
The prevalence of contact lenses was relatively low in Chengdu. The wears had limited knowledge about using and careof contact lens. More education on standard lens wear and care should be provided to wearers. 相似文献11.
12.
Purpose
To investigate changes in tear and ocular surface of patients with keratoconus using rigid gas permeable contact lenses (RGPCL) and compare them against keratoconus patients who were not using lenses as well as a control group of healthy subjects.Methods
24 keratoconus patients using RGPCL (Group 1) 22 patients who were not using lenses (Group 3) and 21 healthy subjects (Group 3) were included in the study. Subjective complaints about the subjects’ eyes have been investigated using the ocular-surface disease index (OSDI). After the control of best-corrected visual acuity, anterior chamber and fundus examinations were performed.Results
Schirmer (p-value = 0.01) and tear break up mean comparison tests (p-value = 0.002) revealed significant differences across different groups but tear osmolarity analysis did not (p-value >0.05). Oxford and OSDI scores were compatible with Schirmer and tear break up test comparisons. (for both p-value = 0.001) Moreover, no statistical differences were seen in impression cytology measures between groups. (p-value >0.05)Conclusions
The erosion in the tear film stability is in line with the erosion in the ocular surface epithelium. Taking into account the statistical indifference between the impression cytology measures across groups, the break up time differences may be attributed to the collagen destruction in tear. 相似文献13.
Purpose
The aim of this work was to investigate the locus and extent of vitronectin (Vn) deposition on ex vivo contact lenses and to determine the influence of wear modality together with surface and bulk characteristics of the lens material.Methods
The quantity and location of Vn deposition on the surfaces of contact lens materials was investigated using a novel on-lens cell attachment assay technique.Results
Vn mapping showed that deposition resulted from lens-corneal interaction rather than solely from the tear film. Higher cell counts on the posterior surface of the lenses were determined in comparison to the anterior surface. Overall gross Vn deposition was greater for high water content-low modulus materials (117 ± 4 average cell count per field) than low water content-high modulus materials (88 ± 6 average cell count per field).Conclusions
The role of Vn in plasmin regulation and upregulation is widely recognised. The findings in this paper suggest that the locus of Vn on the contact lens surface, which is affected by material properties such as modulus, is potentially an important factor in the generation of plasmin in the posterior tear film. Consequently, the potential for materials to affect Vn deposition will influence lens-induced inflammatory processes. 相似文献14.
Purpose
To evaluate a novel fitting algorithm for estimation of alignment curve (AC) radius during orthokeratology lens trial.Methods
Fifty myopic children were recruited in this study. AC radii were estimated by both traditional method using flat K readings and eccentricity values and by a novel fitting algorithm, which was composed of 256 circle fittings using corneal elevation data from the corresponding AC region and a succedent toric fitting based on these calculated AC curvatures. Parameters of the final ordered lenses were determined by fluorescein analysis and corneal topography. The number of lens trials was recorded for each patient, and the consistencies of AC radius and astigmatism between the first trial lenses and the final ordered lenses were tested by Pearson correlations and Bland-Altman plots.Results
The numbers of trials for the novel algorithm and traditional method were 1.2 ± 0.4 times vs. 1.8 ± 0.7 times, respectively, and Mann-Whitney test showed significant difference (z = ?3.27, p = 0.001). AC radii of the first trial lenses estimated by the novel fitting algorithm were more close to that of the final ordered lenses, showing a R square value of 0.994 for the fitting algorithm and 0.927 for the traditional method, respectively. Similar results could also be noticed for astigmatism estimation.Conclusion
AC radius and astigmatism of ortho-k lens could be better estimated by two steps of fitting algorithm using corneal elevation data, which may shorten the time needed for ortho-k lens trial and achieve better lens fitting status. 相似文献15.
Edouard Lafosse Daniel Monsálvez Romín José-Juan Esteve-Taboada James S. Wolffsohn Cristian Talens-Estarelles Santiago García-Lázaro 《Contact lens & anterior eye》2018,41(1):122-127
Purpose
To assess and compare the effect of the corneo-scleral lenses (C-ScL) and scleral lenses (ScL) on tear film parameters and central corneal thickness (CCT) in healthy presbyopic subjects.Methods
Thirty subjects wore two contact lenses (CLs), randomly assigned, of neutral power, but of different diameters, 12.7 mm (C-ScL) and 18 mm (ScL) and being equal in the others parameters: material (HS100) and centre thickness (0.29 mm). At baseline, 20 min after insertion and at 8 h, the tear meniscus area (TMA) and CCT was measured (with optical coherence tomography) as well as tear osmolarity.Results
TMA revealed statistical differences for both lenses at 20 min (p < 0.001), and also at 8 h (p = 0.003), being greater for the C-ScL. CCT showed statistical differences for both lenses at 20 min (p = 0.002), and also at 8 h (p = 0.001), being lower for the C-ScL. Osmolarity did not reveal statistical differences at 20 min (p = 0.29), while it was statistically different at 8 h (p = 0.03), being lower for the C-ScL.Conclusions
C-ScL lead to a lesser reduction in the TMA and a lower induced hypoxic stress than the ScL. Osmolarity levels remained within normal values across the day with no clinical difference between lenses. Both designs can represent a good optical platform for correcting presbyopia as well as protecting the ocular surface by vaulting the cornea. 相似文献16.
Alejandra Consejo Maciej M. Bartuzel D. Robert Iskander 《Contact lens & anterior eye》2017,40(5):293-300
Purpose
To assess whether short-term soft contact lens wear alters the anterior eye surface.Methods
Twenty-two neophyte subjects wore soft contact lenses for a period of five hours. Topography based corneo-scleral limbal radius estimates were derived from height measurements acquired with a corneo-scleral profilometer. Additionally, central corneal thickness (CCT), anterior chamber depth (ACD), corneal curvature radius (R) and white-to-white (WTW) diameter were acquired with an OCT-assisted biometer. Measurements were obtained without lens wear (baseline), immediately after lens removal following five hours of wear and three hours after lens removal.Results
Short-term soft contact lens wear significantly modifies corneo-scleral limbal radius (mean ± SD: 130 ± 74 μm, p << 0.001) and the changes are repeatable. In contrast, the WTW diameter and R were not modified. ACD and CCT were significantly affected but no significant correlations were found between the increment of the limbal radius and the decrease in ACD and CCT. Limbal radius increment was reversed three hours after lens removal for 68% of the subjects but the time course of this reversal was not uniform.Conclusions
It is possible to accurately quantify limbal radius changes as a consequence of soft contact lens wear. The increment in the limbal diameter could reach over 0.5 mm but that alteration does not correspond to changes in WTW diameter and it was not observable to the examiner using a slit lamp. Assessing topographical limbus after contact lens wear could be a tool to optimize the selection of the contact lens, from the perspective of anterior eye surface changes. 相似文献17.
Purpose
To explore the safety profile and overall visual improvement over the course of RGP contact lens wear on children with unilateral or bilateral amblyopia resulting from myopia.Methods
This was a retrospective analysis case series study. Clinical records of 15 patients who were fitted with RGP contact lenses at the Shanghai Eye and EENT Hospital of Fudan University between the period of January 2009 to December 2014 were reviewed. The inclusion criteria for review included patients with myopia of ?3.00DS or greater in one or both eyes and an initial best-corrected visual acuity (BCVA) of logMAR 0.4 or worse for 3 year olds, and logMAR 0.3 or worse for 4 years old and above. One or both myopic eyes were fitted with RGP lenses.Results
15 subjects and 22 amblyopic eyes were included. The mean baseline BCVA was logMAR 0.70 ± 0.38, which improved to a VA of 0.23 ± 0.28 at the time of review (p < 0.05). Baseline myopia also increased from ?8.18 ± 2.93DS to ?11.41 ± 3.76DS (p < 0.05). The final visual acuity at the time of this review was correlated with the initial refractive error (r = ?0.695, p < 0.05) as well as the initial BCVA (r = 0.854, p < 0.05). There was also a strong correlation between initial refractive error and initial BCVA (r = 0.?801, p < 0.05)Conclusion
RGP contact lens wear is a safe and effective refractive treatment option in young children with amblyopia due to myopia. 相似文献18.
Purpose
To compare the current optometric practices and attitudes in the management of keratoconus patients in the UK and Spain.Methods
An online survey (adapted to optometric practices) was distributed via a newsletter emailed by various professional organizations in the UK and Spain.Results
Four hundred and sixty-four practitioners (126 in the UK; 338 in Spain) who prescribed gas permeable GP contact lenses (CLs) more than once per month (54.8% of UK practitioners and 28.1% of practitioners in Spain; p < 0.01) responded to the questionnaire. A combination of multiple factors is considered necessary in the keratoconus detection (79.4% in the UK, 75% in Spain; p = 0.68), and the use of classification criteria is considered relevant (67.5% in the UK, 70.7% in Spain; p = 0.49). There is a high consensus on the consideration that GP CL fitting is more difficult in keratoconus (79.4% in the UK, 80.5% in Spain; p = 0.79) requiring more diagnostic lenses (3.2 ± 1.4 and 3.4 ± 1.2 in the UK and Spain, respectively; p = 0.72) than are necessary for healthy eyes. Using corneal topography is uncommon from both countries (38.1% in the UK, 59.8% in Spain; p < 0.01), with a similar ophthalmologist referral pattern (at initial diagnosis, 50% in both the UK and Spain; p = 1.00). Few cases of co-management with ophthalmologists were noted (no co-management reported by 60.3% in the UK and 72.8% in Spain, p = 0.01).Conclusion
This study provides initial observations and evidence regarding keratoconus management by optometrists in the UK and Spain and shows similarity in the professional practices and attitudes of practitioners in these two countries. 相似文献19.
Mar Seguí-Crespo Javier Parra Picó Pedro Ruíz Fortes Alberto Artola Reig Francisco J. Blanes-Mompó Rafael J. Pérez-Cambrodí 《Contact lens & anterior eye》2018,41(2):187-192
Purpose
To determine the usefulness of a silicone-hydrogel bandage contact lens (BCL) in the immediate postoperative period after uneventful myopic laser in-situ keratomileusis (LASIK).Methods
The study design was randomized but not masked and data collection was prospective. This study comprised 51 consecutive myopic eyes intervened by means of the LASIK technique to compensate their refractive error. Patients were randomly assigned to two different groups. The experimental group included 24 eyes of 12 patients that were fitted with a BCL immediately after the flap replacement. The control group included 27 eyes of 14 patients with no BCL. Patients were examined 24 h after the surgery; the experimental group was analyzed immediately after the extraction of the BCL. Postoperative uncorrected distance visual acuity (UDVA) and postoperative topographic indexes were compared to baseline in both groups.Results
The experimental group achieved worse results in the majority of the studied variables. Postoperative UDVA was worse in experimental group (p < 0.01). Likewise, corneal asphericity (Q) was significantly higher in experimental group (p = 0.024). Topographic indexes showed higher asymmetry in the corneal maps pertaining to experimental group. Specifically, the index of surface variance (ISV) (p = 0.017) and index of vertical asymmetry (IVA) (p = 0.031) were higher in experimental group. Also, the postoperative central corneal thickness (CCT) resulted in higher values for eyes pertaining to experimental group.Conclusions
The fitting of a silicone-hydrogel BCL after uneventful LASIK provokes morphological changes in the ocular structures that may lead to a worse UDVA secondary to a higher postoperative CCT and corneal edema. 相似文献20.