一种两用插拔LED灯管的解决方案

插拔管LED采用插拔的形式组接灯具,方便快捷,使用广泛.目前,插拔管灯的灯头有G24D(2针)和G24Q(4针),主要因为一种是直接市电接入(L和N),另外一种是预热启动的外置电子镇流器驱动.两者外观类似,但使用电特性差异很大.通俗的说法是两针市电接入灯头名称为G24D,四针为镇流器输出接入灯头名称为G24Q.现阶段,...     

MYG20型压敏电阻器参数表

型号压敏电压 (V)最大诈续T作最大限制8/20 ps能量耐量Zms通流容量8/20 ps最大静态功率静态电容IkHz外形尺寸(恤) 电压(V)ACDCVAJAWPFDT士1 .0W士1 .0dMYG20G05K47045~5230381041 .01 .0500 .014507 .53 .55.00.6MYG20G07K470932 .51 .81250 .021 1509.03 .95 .00 .6935.04.52500,052200135407.50,8MYG20G10K47093108 .55000 .15500174 .07 .50 .8MYG20G14K47093203010000 .213000234.6101 .0MYG20G20K470MYG20G05K56050~6235451231 .01 .0500 .01 400l7 .53.55.00.61 102 .52 .21250 .029509.0405.00.6MYG20G07K5601…     

中国4G研究与评估同步于国际日韩树LTE榜样

据10月份ITU结束各国的4G（IMT—Advanced）技术标准征集工作的时限已经只有两个月之余了,业界对LTE和B4G的关注日趋热烈。前不久在未来移动通信论坛承办的“新一代移动通信国际高峰论坛暨ICB3G-2009”会议上,多位国际／国内4G专家的演讲可谓有“高度含金量”,本刊特此与未来移动通信论坛合作,将关于4G的国际研发和合作的最新进展与读者分享。     

日开发出最快光通信技术每秒可传4部电影

讨论第3代以后移动电话技术的ICB3G-2004(International Conference on Beyond 3G Mobile Communications-2004)5月28-29日在东京举行。目前正在探索下一代技术的中国和韩国表示，将在2006年推出名为“Wi-Bro”的高速无线接人技术。     

4G研究进入关键年

今年是中日韩开展4G研究交流合作的第7年。据悉，中日韩以及中国和欧盟国家的4G研究合作最新动向，将在6月25-26日举办的“新一代移动通信国际高峰论坛暨ICB3G-2009”大会上向业界详细公布。今年的会议内容将重点关注“国家政策法规、频谱策略及IMT-A战略发展研究计划”、“IMT-A、3G演进及相关技术、标准化活动”、“新一代移动通信技术战略合作”等议题。     

李世鹤：3G瓶颈直接影响LTE前景

主流国际运营商几乎都打出了LTE的试商用时间表，国内的TD-LTE研发也在加快速度，并且计划明年在世博会上“一露身手”。但“中国3G之父”李世鹤在ICB3G-2009会议上却给LTE的组网与实际需求提出了质疑。     

一种高性能、低成本、大功率高压钠灯用电子镇流器

<正> 前言 高压钠灯电子镇流器是在普通荧光灯电子镇流器基础上发展起来的,其原理与普通荧光灯电子镇流器是很接近的,都是一种高频交流交换器。但在电路上要比普通荧光灯电子镇流器复杂得多,其主要原因是: 1.高压钠灯工作于电弧放电状态,灯管内的气体压强受环境温度的影响很     

基于控制器L6585的58W双T8灯管电子镇流器

L6585是意法半导体公司生产的一种集功率因数校正控制器和电子镇流器控制器于同一芯片上的组合IC,用其可以设计高性能和高可靠不同类型的荧光灯交流电子镇流器.L6585的结构及主要特点1.引脚功能L6585采用20引脚SO封装,引脚排列如图1所示.L6585的各     

实现TD及TD-LTE有序衔接发展——新一代移动通信高峰论坛综述

新一代移动通信国际高峰论坛暨B3G国际会议（ICB3G——2009）日前在北京落幕。国家发展和改革委员会副主任张晓强、科技部副部长杜占元、工业和信息化部总工程师苏金生等参加大会并发表讲话。与会专家认为,TD—LTE是TD—SCDMA长期演进及向IMT-Advanced发展的重要路径,TD—SCDMA与TD—LTE在相当长的时间内将并存发展,要实现TD—SCDMA及TD—LTE的有序衔接发展。     

关于IEC 60598-1(四)

1（1）问题：有一个带镇流器的灯具,内部有金属反光镜,镇流器固定在塑料材料上,并带有一个比例漫射器。     

Design of fluorescent lamp ballast with PFC using a power piezoelectric transformer

An investigation of a high-power piezoelectric transformer (PT) as a potential component for a fluorescent lamp (FL) ballast with power factor correction (PFC) is discussed. The attractiveness of the PT is primarily the simplicity of the resulting circuit, and it is easy to be produced in mass with a low cost. A single-stage charge-pump PFC ballast using a PT is proposed. The proposed ballast circuit improved the drawbacks of the conventional voltage-source charge-pump PFC (VS-CPPFC) scheme. Empirical PT modeling based on power level excitation is performed to design the proposed circuit, and the experimental and simulation results are provided to verify theoretical analysis.     

A Multistage-Responsive Antibody-Delivery Strategy to Improve Immunotherapy for NSCLC Brain Metastasis by Ultrasensitive Releasing and Tumor-Anchoring

Immune checkpoint blockade (ICB) therapy has emerged as a promising approach in clinical oncology. For brain metastases, the presence of the robust blood–brain barrier (BBB) and potential immune-related adverse events (irAEs) pose significant challenges. Here, a multistage-responsive antibody-delivery strategy is developed for non-small cell lung cancer (NSCLC) brain metastases, with the ultra-pH sensitivity borate bonds. The antibody-delivery nanoformulation (MB-aPDL1) is able to maintain the “silent state” in health tissue, cross the BBB/BTB by the GLUT1-mediated transcytosis, release the functionalized aPDL1 responsively, and promote the aPDL1 tumor-anchoring. In the in vivo tumor region, the MB-aPDL1 rapidly releases the activated BPA₆-aPDL1, which successfully anchors to the tumor cells and improves the efficiency of ICB therapy. The two in vivo ICB therapy studies show a significant tumor growth inhibition from the MB-aPDL1 with an encouraging cure rate of 20% for the NSCLC brain metastases, due to enhanced immune response in tumor, commendably with less behavioral adverse reactions and liver damage. Taken together, this antibody-delivery strategy holds substantial potential for application in clinical treatment of brain metastases.     

An Integrated Nanoaircraft Carrier Modulating Antitumor Immunity to Enhance Immune Checkpoint Blockade Therapy

Immune checkpoint blockade (ICB) therapy revolutionizes cancer therapeutics. However, the effectiveness of ICB therapy is restricted. Focusing on the tumor itself and the immune system, an integrated nanoaircraft carrier that coloaded three therapeutic agents (NNG/OTC) to eradicate tumor cells, enhance T-cells intratumoral infiltration, and relieve the inhibition of tumor immunosuppressive microenvironment (TIM) is designed. First, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is used to combine with oxaliplatin for reducing tumor burden. Second, oxaliplatin is used to elicit immunogenic cell death and combine with cytosine-phosphate-guanine (CpG) to promote dendritic cells maturation, ultimately increasing T-cells intratumoral infiltration. Third, CpG is further used to repolarize M2 type of tumor-associated macrophages, thus reversing immunosuppression of TIM. The nanoaircraft carrier can effectively arrive at the tumor site and detach small-sized nanoparticles under a high concentration of matrix metalloproteinase-2, which promotes deep tumor penetration. Under the mediation of targeting ligands, three therapeutic agents loaded in small-sized nanoparticles could be launched to their target cells. NNG/OTC modulates the antitumor immunity and exhibits excellent tumor inhibition when in combination with ICB therapy, indicating the increased response of ICB therapy. Collectively, NNG/OTC can co-deliver various drugs with different physicochemical properties and provide a promising strategy for enhancing ICB therapy.     

Toward Biomaterials for Enhancing Immune Checkpoint Blockade Therapy

Despite the remarkable progress in immune checkpoint blockade (ICB) therapy for cancer treatment, low objective response and immune‐related side effects (immune‐related adverse events, irAEs) limit the further development of ICBs. To address these challenges and enhance the efficiency of cancer immunotherapy, the emerging interest has focused on manipulating biomaterials to form innovational drug delivery systems that are necessary to effectively deliver immune checkpoint inhibitors. Such biomaterial‐based strategies can improve accumulation, control release, and enhance retention of checkpoint inhibitors within target locations while simultaneously reducing drug exposure for off‐target tissues, thereby optimizing both the efficacy and safety. In addition, with the assistance of biomaterials, combinations of ICB and conventional treatment strategies including chemotherapy, radiotherapy, and phototherapy are designed to further enhance the response rate of ICB. This review focuses on the latest reports on engineering biomaterials to improve the antitumor efficiency of ICB, with stress on antibody‐, gene‐, and trap protein–based immune checkpoint blockade strategies and their combinations with conventional therapies. Challenges and future trends in engineering biomaterials to modulate immune checkpoint therapy are discussed.     

250W高压钠灯电子镇流器的研究

为满足人们对绿色照明的要求,该文设计了节能、高功率因数及总谐波失真低的高压钠灯电子镇流器来替代传统的电感式镇流器,采用有源功率因数校正、恒功率控制、低频方波驱动的三级式结构的电路设计,并搭建了样机,实现了160V～265V宽电压输入,功率因数PF≥0.99,总谐波畸变因数THD≤9．1％,电路可靠工作,通过了电磁兼容传导干扰测试。     

Ferroptosis and Pyroptosis Co-Activated Nanomodulator for “Cold” Tumor Immunotherapy and Lung Metastasis Inhibition

Immune checkpoint blockade (ICB) therapy is an emerging strategy for cancer immunotherapy; however, the actual effects of ICB therapy are greatly limited by the immunosuppressive tumor microenvironment (TME, i.e., “cold” tumors). Although engineered nanomaterials display significant importance to regulate TME in cancer treatment, most of them focus on “immunosilent” apoptotic processes that cannot elicit sufficient immune responses for further immunotherapy. Herein, a GSH-responsive nanomodulator is reported that can reverse the immunosuppressive TME for “cold” tumor immunotherapy and lung metastasis inhibition through simultaneous ferroptosis and pyroptosis induction. The nanomodulator is constructed by loading FDA-approved sulfasalazine (SAS) and doxorubicin (DOX) on disulfide-doped organosilica hybrid micelles, where SAS and DOX are released through the GSH-stimulated rupture of micelles to induce ferroptosis and pyroptosis, respectively, promoting dendritic cells (DCs) maturation and cytotoxic T lymphocytes (CTLs) elevation through massive tumor-associated antigen release. In vivo experimental results verify that desirable tumor destruction of the nanomodulator at low concentrations is achieved. More importantly, combination of this nanomodulator and programed death ligand-1 antibodies significantly inhibits primary tumors and distant lung metastases as a result of elevated mature DCs and CTLs. This strategy to modulate immunosuppressive TME by nanomodulator-induced non-apoptotic death provides a new promising paradigm for ICB therapy.     

集成元件印制板技术

集成元件印制板是把无源元件(如电阻、电容和电感)分别或综合集成到PCB(印制板)内层而形成的,它是新一代HDI/BUM板发展的一个重要方面,并且随着集成电路(IC)的高集成化、高频信号和高速数字信号传输的发展,要求印制板有更好的特性阻抗和更小的电磁干扰,采用集成元件印制板既能提高印制板的高密性又能达到更好的特性阻抗匹配和更小的电磁干扰.介绍了集成电容印制板和集成电阻印制板的材料及工艺过程.     

Green Concerns in Federated Learning over 6G

As Information,Communications,and Data Technology(ICDT)are deeply integrated,the research of 6G gradually rises.Meanwhile,feder-ated learning(FL)as a distribute...     

A novel single-stage push-pull electronic ballast with high inputpower factor

A novel single-stage push-pull electronic ballast with high input power factor is presented in this paper. The proposed electronic ballast combines the front-end power-factor corrector and push-pull converter into a single-stage power converter. Compared to the single-stage class-D electronic ballast, the proposed circuit does not require an isolated driver. The control of the circuit is easier and the cost less. The circuit of the ballast is analyzed and the design guidelines are listed. The experimental results verify the theoretical derivation     

A novel single-stage constant-wattage high-power-factor electronicballast

A novel single-stage high-power-factor electronic ballast is presented in this paper. The ballast is obtained from the integration of a buck-boost converter and a half-bridge LC resonant inverter. The ballast features lamp power regulation against line voltage fluctuations together with high power factor and dimming capability. The steady-state analysis of the ballast is performed and a low-frequency model of the input stage is derived. A design example, including closed-loop circuitry, is also presented. Finally, some experimental results from a laboratory prototype are shown