The current situation of lagophthalmos and keratopathy of leprosy in PR China

OBJECTIVE: Previous studies have reported poorer health behaviors in high vs. low hostile subjects. The role of stress in these observed differences has not been explored although interpersonal stress does increase cardiovascular response in high hostiles. Given evidence that stress may induce increased salt-intake, this study examined the role of hostility and interpersonal stress in increasing sodium consumption in addition to cardiovascular reactivity. METHOD: Sixty-nine male undergraduates were categorized into high (HiHo) and low hostile (LoHo) groups based on Buss-Durkee Hostility Inventory scores. Subjects engaged in either a math task with harassment, math task without harassment, or a control/rest condition. Sodium intake was assessed posttask by having subjects ingest a sodium-free soup that was presented with a saltshaker without any comments. Cardiovascular measures were also recorded. RESULTS: HiHo subjects consumed more salt than LoHo subjects irrespective of experimental condition. HiHo subjects who were harassed also exhibited greater cardiac output, systolic blood pressure, and forearm blood flow than did HiHo nonharassed, HiHo control, or LoHo subjects. CONCLUSION: HiHo subjects exhibited increased salt-intake, although evidence for stress-induced salt-intake was not obtained. Nonetheless, the combination of salt and stress may contribute to the cardiovascular hyperreactivity and risk for cardiovascular disease in hostile individuals.     

Developmental toxicity of steviol, a metabolite of stevioside, in the hamster

Family history of hypertension (positive and negative) and gender groups were compared on cardiovascular responses at rest, during stressors and during recovery. Two tasks were employed, mental arithmetic and an anger recall interview. Both levels and reactivity measures of blood pressure, heart rate, cardiac output and total peripheral resistance were included. In addition, participants filled out several questionnaires measuring state feelings during the task and recovery periods, trait anger/hostility and emotions. Both men and women with a positive family history of hypertension exhibited higher tonic levels of blood pressure and heart rate at rest, recovery and during both tasks. They also exhibited greater heart rate reactivity during the mental arithmetic task and greater blood pressure reactivity to both tasks when post-math recovery, but not initial rest, was used as a covariate. Positive family history individuals reported less trust and gregariousness, more depression and aggression, less awareness of somatic responses to the tasks and less effort to relax during the post-task rest periods. Finally, significant correlations were found between low anger expression how anger experience and high anger control and task SBP levels in positive family history individuals.     

Cynical hostility and vulnerability to disease: Social support, life stress, and physiological response to conflict.

34 extremely high and 34 low scorers on the hostility (Ho) scale proposed by W. Cook and D. Medley (1954) were selected from a pool of male undergraduates. Consistent with previous findings, high-Ho Ss reported greater anger proneness and a more cynical view of others than did low-Ho Ss. The high-Ho group also tended to be more hostile and less friendly during role-played interactions involving high and low levels of interpersonal conflict. High-Ho Ss displayed greater diastolic blood pressure reactivity during interpersonal conflict and reported less social support and more negative life events and daily irritants then did low-Ho Ss. Results support the interpretations of the Ho scale as a measure of cynical hostility and are consistent with the hypothesis that hostility is related to disease by way of excessive physiological reactivity and a generally stressful, unsupportive social network. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Hostility, cigarette smoking, and responses to a lab-based social stressor.

High-trait hostility is associated with persistent cigarette smoking. To better understand mechanisms that may account for this association, we examined the effects of acute smoking abstinence and delayed versus immediate smoking reinstatement on responses to a social stressor among 48 low hostile (LH) and 48 high hostile (HH) smokers. Participants completed two laboratory sessions, one before which they had smoked ad lib and one before which they had abstained for the prior 12 hr. During each session, participants completed a stressful speaking task and then smoked immediately after the stressor or after a 15-min delay. The effect of immediate versus delayed smoking reinstatement on recovery in negative mood was significantly moderated by hostility. When reinstatement was delayed, HH participants showed significant increases in negative mood over time, whereas LH participants showed little change. When reinstatement was immediate, HH and LH smokers showed similar significant decreases in negative mood. Smoking abstinence did not moderate hostility effects. Cigarette smoking may prevent continuing increases in negative mood after social stress in HH smokers, which may partially explain their low rates of quitting. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Body fat distribution and hemodynamic stress responses in premenopausal obese women: A preliminary study.

To examine the relationship between body fat distribution and hemodynamic stress responses, cardiovascular responses to a speech task and a forehead cold pressor task were evaluated with 24 premenopausal women classified a priori as either centrally or peripherally obese. Results showed that women with central adiposity exhibited greater stress-related increases in diastolic blood pressure and total peripheral resistance, whereas women with peripheral adiposity exhibited greater stress-related increases in cardiac output. Depression, self-consciousness, hostility, and mood scores did not explain significant variance in the stress response differences between regional adiposity groups. The findings suggest that central adiposity may increase the risk of cardiovascular disease in women at least in part by enhancing vascular responses to stress. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cardiovascular and neurohumoral responses to behavioral challenge as a function of race and sex.

Cardiovascular and hormonal responses to a structured interview, an electronic video game, a cold pressor test, and exercise on a bicycle ergometer were assessed in 83 normotensive Black and White men and women (aged 25–44 yrs). Black Ss showed significantly greater diastolic blood pressure (DBP) responses than White Ss during the cold pressor test, which were not accounted for by an increase in plasma catecholamines. Exercise produced reliably greater systolic blood pressure (SBP) increases in Black women than in Black men or White women. Men showed significantly greater SBP and DBP changes than women during the video game. The pattern of physiological reactivity elicited by challenge may be related to the Ss' race and sex. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Familial environment associated with Type A behaviors and psychophysiological responses to stress in children.

Studied the characteristics of family environments associated with children"s Type A behaviors, anger frequency and expression, hostile outlook, hostility displayed during an interview, and cardiovascular responses to laboratory stressors. Two measures of family environment, Positive Affiliation and Authoritarianism, were derived by a factor analysis of the Family Environment Scale completed by parents. 66 girls and 48 boys enrolled in Grades 2–12 from 114 families served as Ss. Families scoring low on Positive Affiliation had children who were assessed as more angry and hostile. Boys from these families had a more pronounced heart rate response to all laboratory stressors. High Authoritarianism scores in combination with low Positive Affiliation scores in families predicted a heightened heart rate response in boys. Sex differences in the pattern of associations among family and child characteristics were also found. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Relaxation training and cardiovascular response to experimental stressors.

Blood pressure (BP) and heart rate were measured in 36 Ss (mean age 33 yrs) during periods of rest, intentional relaxation, unsignaled reaction time (RT), cold pressor tasks, and recovery periods, both before and after 4 wks of progressive relaxation training, transcendental meditation analog treatment, or an assessment control condition. Both types of relaxation training resulted in significant reductions in BP, but not heart rate, levels across all posttreatment assessment intervals (baseline, stress periods, and stress recovery). Relaxation training did not reduce cardiovascular response during stress periods, but did result in more rapid BP reductions in stress recovery periods. Scores on the Jenkins Activity Survey were related to posttreatment BP level during the RT task, with high scorers showing higher BPs than low scorers. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Parental history of hypertension and hostility moderate cardiovascular responses to interpersonal conflict

A parental history of hypertension has been implicated in the development of hypertension, perhaps by virtue of an elevated cardiovascular response to stress. Similarly, hostility has been hypothesized to be linked to cardiovascular disease through cardiovascular hyperreactivity. The interaction of parental history and hostility in moderating cardiovascular response has been infrequently examined, though research suggests the two may be linked through familial factors. The present study examined the cardiovascular response of 98 healthy young adult males categorized as offspring of hypertensive subjects (PH+) or offspring of normotensive subjects (PH-) and as high or low hostile, based on Cook-Medley Hostility scores (HiHo vs. LoHo). Subjects were exposed to either an harassment or non-harassment stressor. Results indicated elevated cardiac output and forearm blood flow responses in PH+/HiHo subjects who were harassed as compared to any other harassed subject and all non-harassed individuals. This hemodynamic response pattern of elevated blood flow suggests a mechanism of hypertensive disease development.     

Organizational justice and men's likelihood to sexually harass: The moderating role of sexism and personality.

This study demonstrated relations between men's perceptions of organizational justice and increased sexual harassment proclivities. Respondents reported higher likelihood to sexually harass under conditions of low interactional justice, suggesting that sexual harassment likelihood may increase as a response to perceived injustice. Moreover, the relation between justice and sexual harassment proclivities was especially marked for men low in agreeableness and high in hostile sexism. This finding is consistent with an interactionist perspective, suggesting that individual differences in hostility in general and toward women in particular affect how a person reacts to perceived unfairness. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social influence, marriage, and the heart: Cardiovascular consequences of interpersonal control in husbands and wives.

Examined the effects of exerting social influence or control on cardiovascular responses in 45 married couples (aged 20–40 yrs) who were undergraduates. Compared with husbands discussing a problem with their wives, husbands attempting to influence or persuade their wives displayed larger increases in systolic blood pressure (SBP) before and during the discussion. Furthermore, these physiological effects were accompanied by increases in anger and a more hostile and coldly assertive interpersonal style. Although wives who engaged in social influence attempts displayed generally similar behavior, they did not show the elevated SBP response or anger. Results are discussed in terms of the social context of cardiovascular reactivity and potential marital factors in cardiovascular health. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cardiovascular responses during effortful active coping and acute experience of anger in women

This study addresses the question of whether effortful active coping and anger provocation add in their effects on cardiovascular responses. Heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) responses of 64 female students were collected during an active versus nonactive coping task with and without provocation. After a baseline period, women did mental arithmetic (active coping) or read numbers aloud (nonactive coping). Half of each group was then additionally provoked. Ratings of the emotional states (Positive and Negative Affect Scale) indicate that provocation led to an increase in anger, but not in fear or negative or positive affect. Effortful active coping and provocation elevated cardiovascular activity. Although active coping enhanced all cardiovascular variables, provocation particularly affected HR and DBP. The effects of active coping and provocation on HR and DBP but not on SBP were additive and probably were produced by different physiological mechanisms.     

Chronic stress influences cardiovascular and neuroendocrine responses during acute stress and recovery, especially in men.

This study tests the influence of chronic stress on cardiovascular and neuroendocrine responses to and recovery from acute stressors and whether the effects are gender specific. Sixty-two healthy, middle-aged persons (50% women) performed mental-arithmetic and public-speaking tasks and relaxed thereafter for 1 hr while their cardiovascular and neuroendocrine functions were measured. Participants with higher levels of chronic stress showed lower systolic blood pressure (SBP) and epinephrine (E; men only) and marginally lower levels of norepinephrine (NE) responses to the tasks and showed lower levels of cortisol and marginally lower NE responses during recovery. Relative to women, men had high diastolic blood pressure (DBP) responses to the tasks and high SBP, DBP, and E responses during recovery. Gender differences in cardiovascular disease in midlife may be due to gender differences in inability to recover quickly, in addition to enhanced acute-stress response. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Psychosocial predictors of natural killer cell mobilization during marital conflict.

This study examined how specific emotions relate to autonomic nervous and immune system parameters and whether cynical hostility moderates this relationship. Forty-one married couples participated in a 15-min discussion about a marital problem. Observers recorded spouses' emotional expressions during the discussion, and cardiovascular, neuroendocrine, and immunologic parameters were assessed throughout the laboratory session. Among men high in cynical hostility, anger displayed during the conflict was associated with greater elevations in systolic and diastolic blood pressure, cortisol, and increases in natural killer cell numbers and cytotoxicity. Among men low in cynical hostility, anger was associated with smaller increases in heart rate and natural killer cell cytotoxicity. These findings suggest that models describing the impact of stress on physiology should be refined to reflect the joint contribution of situational and dispositional variables. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Hostility and Distraction Have Differential Influences on Cardiovascular Recovery From Anger Recall in Women.

This study investigated the relation of dispositional hostility to cardiovascular reactivity during an anger-recall task and of hostility and distraction to posttask recovery in 80 healthy women (ages 18-30). Half were randomly assigned to distraction during recovery. Hostility predicted slower systolic blood pressure and preejection period during recovery. Distraction was related to faster cardiac recovery, higher high-frequency (HF) power, lower low-frequency (LF) power and LF:HF ratios, and lower state anger and rumination during recovery. These results indicate deleterious influences of hostility on cardiovascular recovery but not during anger recall. The findings also show beneficial effects of distraction in expediting cardiovascular recovery, possibly through reducing rumination and anger. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Interpersonal aggression and the Type A coronary-prone behavior pattern: A theoretical distinction and practical implications.

In Study 1, 85 male undergraduates were classified as Type A (coronary prone) or Type B (noncoronary prone) on the basis of scores on the Jenkins Activity Survey. Ss participated in a version of A. H. Buss's (1961) teacher–learner procedure that allowed the isolation of hostile from instrumental acts. Results indicate that a prior task frustration produced greater aggression by Type A's than Type B's, but only under conditions where the aggressive act could not affect a confederate's immediate performance (i.e., hostile aggression). Study 2 examined the representation of Type A's and Type B's among 20 women in treatment for child abuse, 20 women who were victims of spouse abuse, and 20 control women. Findings show that Type A's were more likely than Type B's to exhibit the extreme hostility found in child abuse. Both studies suggest that a lack of control may underlie the greater aggression displayed by Type A's and Type B's. (39 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Stability of individual differences in physiological responses to stress.

Evaluated cardiovascular and plasma catecholamine responses to an audiovisual conflict task in 56 males (aged 25–59 yrs), classified as Type A (coronary prone) or Type B (noncoronary prone), and high or low reactors to a stressful subtraction task administered 2 mo earlier. A high/low-reactor classification showed positive associations with systolic blood pressure (BP), diastolic BP, heart rate, and plasma catecholamines. Related personality characteristics (e.g., feelings of anger, evaluative anxiety) were positively associated with being a high reactor, whereas the outward display of hostile impulses showed an inverse relationship. Findings are discussed in terms of a distinction between anger and hostility and the role of evaluation apprehension in Type A behavior. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Changes in and stability of hostile characteristics: Results from a 4-year longitudinal study of children.

Changes in and stability of hostility characteristics and their relationship to age, sex, and family support were examined among 108 10–18 yr olds in a 4-yr longitudinal study. Clinical ratings of Structured Interview potential for hostility, self-reported MMPI-derived hostile attitudes, and perceptions of family support were obtained at study entry and at follow-up when Ss were aged 15–21 yrs. Results showed relative stability of hostility rankings across 4 yrs, with males being more hostile than females. Both sexes increased in hostility over time, with the greatest increase in Ss who perceived low family support at follow-up and whose parents perceived high family support at study entry. Results are consistent with notions that early signs of hostility are risk factors for later development of coronary disease and that family environment influences development of hostility. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effects of hostility on ambulatory blood pressure and mood during daily living in healthy adults.

This study (a) tested the effects of hostile attributes on ambulatory blood pressure (BP), heart rate, and mood monitored repeatedly over 3 days in 100 healthy men and women and (b) determined whether the cardiovascular effects of trait hostility were moderated by mood. Multilevel random-coefficients regression analyses showed that hostile individuals exhibited higher systolic and diastolic BP and rated their current moods as more negative and less positive throughout the monitoring. Individuals low in hostility exhibited high BP only during the few occasions when they experienced negative mood. However, these patterns were true only when participants were classified by Potential for Hostility ratings from the Structured Interview (R. H. Rosenman, 1978), not by the Cynical Hostile Attitudes score derived from the Cook-Medley scale. Results provide convergent and ecological validity of interview rating of hostility and illuminate one possible dynamic mechanism by which overt hostile behaviors might contribute to the rates of increased cardiovascular morbidity and mortality. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Patterns of cardiovascular responses to stress as a function of race and parental hypertension in men.

Investigated cardiovascular responses to 12 stressors known to elicit either beta-adrenergic (mental arithmetic) or alpha-adrenergic (forehead cold pressor) reactivity in 27 Black and 29 White normotensive male college undergraduates. Ss in each group were selected for presence or absence of parental hypertension. Based on previous research (e.g., F. M. Abboud and J. W. Eckstein [1966], H. Barcroft et al [1960]) Blacks were expected to show smaller cardiovascular responses to the beta-adrenergic mental arithmetic task and greater responses to the alpha-adrenergic cold pressor relative to the Whites. Unlike previous findings, no significant racial differences in cardiovascular responses were found during either task. However, Black participants had significantly higher systolic blood pressure and diastolic blood pressure levels throughout the cold pressor periods. (PsycINFO Database Record (c) 2010 APA, all rights reserved)