The Effect of Fullerene C60 and its Amine Derivative on the ZDDP Antioxidative Functionality

In this work we describe the effect of both fullerene and its oil-soluble amine derivative on antioxidative properties of ZDDP (zinc dialkyldithiophosphate, alky groups: isobutyl and isoamyl). An oxidation reaction in the presence of AIBN (as an initiator) was chosen as chemical probe to investigate mutual interaction of ZDDP with fullerene and its derivative. According to the experimental results, both fullerene C₆₀ and its amine derivative show more antioxidative properties than ZDDP. Experimentally, it is concluded that the presence of these species increase the effect of ZDDP as antioxidant. This effect could be experimentally described in terms of the metal center of ZDDP.     

气相色谱-质谱法测定夜来香种子油中的脂肪酸

利用气相色谱-质谱联用技术对夜来香种子油中的脂肪酸(经甲酯化后)进行分离和定性,共鉴定出二十种脂肪酸。并用归一化法确定出各成分在夜来香种子油中的相对含量。对所得的结果进行了讨论。     

气相色谱法同时测定食品中34种脂肪酸

本文建立了气相色谱法同时测定食品中34种脂肪酸的方法。食品中的脂肪酸经酸水解后,用石油醚-乙醚(1+1)提取脂肪,KOH/CH3OH皂化和甲酯化,生成脂肪酸甲酯,GC-FID检测。该方法回收率在91.28%～109.59%之间,相对标准偏差小于8.48%,34种脂肪酸的检出限在1.32mg/kg～3.36mg/kg之间,能满足实际检测工作的需要。本方法准确、灵敏,检测的脂肪酸种类多,具有实际推广价值。     

Influence of omega fatty acids on skin permeation of a coenzyme Q10 nanoemulsion cream formulation: characterization,in silico and ex vivo determination

Objective: The aim of this study was to develop a coenzyme Q10 nanoemulsion cream, characterize and to determine the influence of omega fatty acids on the delivery of coenzyme Q10 across model skin membrane via ex vivo and in silico techniques.

Methods: Coenzyme Q10 nanoemulsion creams were prepared using natural edible oils such as linseed, evening primrose, and olive oil. Their mechanical features and ability to deliver CoQ10 across rat skin were characterized. Computational docking analysis was performed for in silico evaluation of CoQ10 and omega fatty acid interactions.

Results: Linseed, evening primrose, and olive oils each produced nano-sized emulsion creams (343.93–409.86?nm) and exhibited excellent rheological features. The computerized docking studies showed favorable interactions between CoQ10 and omega fatty acids that could improve skin permeation. The three edible-oil nanoemulsion creams displayed higher ex vivo skin permeation and drug flux compared to the liquid-paraffin control cream. The linseed oil formulation displayed the highest skin permeation (3.97?±?0.91?mg/cm²) and drug flux (0.19?±?0.05?mg/cm²/h).

Conclusion: CoQ10 loaded-linseed oil nanoemulsion cream displayed the highest skin permeation. The highest permeation showed by linseed oil nanoemulsion cream may be due to the presence of omega-3, -6, and -9 fatty acids which might serve as permeation enhancers. This indicated that the edible oil nanoemulsion creams have potential as drug vehicles that enhance CoQ10 delivery across skin.     

GC/MS分析纸浆及沉积树脂中脂肪酸组成

本文用色谱-质谱联用分析了纸浆及其沉积物的树脂中的脂肪酸成分。结果表明:纸浆中脂肪酸成分主要是油酸、9,11-十八碳二烯酸和软脂酸。沉积树脂的脂肪配成分基本上与之相同。纸浆中甘油三酸酯的脂肪酸的主要成分是油酸和软脂酸。纸浆中的甘油三酸酯是导致制浆造纸过程中产生树脂障碍的主要有害成分之一。     

红外光谱法测定柴油中脂肪酸甲酯的检出限及不确定度评定

柴油中脂肪酸甲酯含量的测定广泛采用红外光谱法,针对此方法的检测能力和准确性进行了研究.试验测定红外光谱法检测柴油中脂肪酸甲酯的检出限和定量限分别为0.0066 g/L和0.0220 g/L,加标回收率为99.2％～101.3％,结果表明试验方法具备良好的准确性,能够准确灵敏地检测柴油中脂肪酸甲酯.测定的合成相对标准不确...     

脂肪酰基氨基酸在矿物润滑油中的摩擦磨损特性

通过摩擦磨损试验研究了月桂酰基谷氨酸、月桂酰基甘氨酸和月桂酰基丙氨酸对HVI350矿物润滑油摩擦磨损性能的影响,采用扫描电子显微镜(SEM)和X射线光电子能谱仪(XPS)分析了磨斑表面形貌和表面膜化学特征。结果表明,在一定浓度范围内,三种脂肪酰基氨基酸均可改善矿物润滑油的抗磨减摩性能,其抗磨减摩机制是氨基酸在摩擦表面形成具有抗磨减摩作用的吸附膜和摩擦化学反应膜。