共查询到20条相似文献,搜索用时 13 毫秒
1.
Francisco J. Osuna-Prieto Francisco M. Acosta Unai A. Perez de Arrilucea Le Floch Blanca Riquelme-Gallego Elisa Merchan-Ramirez Huiwen Xu Juan Carlos De La Cruz-Mrquez Francisco J. Amaro-Gahete Jose A. Llamas-Elvira Eva M. Trivio-Ibez Antonio Segura-Carretero Jonatan R Ruiz 《Journal of the International Society of Sports Nutrition》2022,19(1):417
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Y Liu R Lange J Langanky T Hamma B Yang JM Steinacker 《Journal of the International Society of Sports Nutrition》2012,9(1):37
ABSTRACT: BACKGROUND: Exercise causes a variety of physiological and metabolic changes that can in turn reduce exercise tolerance. One of the potential mechanisms responsible for fatigue is "exercise-induced hyperammonemia". Previous studies have shown that supplementation with amino acids can increase training tolerance. The alpha-keto acids are biochemical analogs of amino acids and can be converted to amino acids through transamination, thus reducing the cellular ammonia level. This double blind, placebo-controlled study was designed to investigate the effects of alpha-keto acid supplementation (KAS) on training tolerance, training effect, and stress-recovery state. METHODS: Thirty-three untrained young male adults underwent four weeks of training (5 sessions/week; 30 minutes running at the individual anaerobic threshold followed by 3 x 3 minute sprints/each session). Throughout the 4 weeks of training and one week of recovery, subjects took alpha-ketoglutarate (AKG group, 0.2 g/kg/d, n=9), branched-chain keto acids (BCKA group, 0.2 g/kg/d, n=12) or isocaloric placebo (control group, n=12) daily. RESULTS: The 4th week training volume, maximum power output and muscle torque were higher in the AKG group (175+/-42 min, 412+/-49 Watts and 293+/-58 Newton meters, respectively, P<0.05) and the BCKA group (158+/-35, 390+/-29 and 273+/-47, P<0.05) than in the control group (92+/-70, 381+/-67 and 233+/-43). The general stress and emotional exhaustion as assessed by the rest-stress-questionnaire-sport after the 3rd week of training increased significantly in the control group (P<0.05), but not in the KAS groups. CONCLUSIONS: Under KAS, subjects could bear a higher training volume and reach a higher power output and peak muscle torque, accompanied by a better stress-recovery-state. Thus, KAS improves exercise tolerance and training effects along with a better stress-recovery state. Whether the improved training tolerance by KAS is associated with effects on ammonia homeostasis requires further observation. 相似文献
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Christian J Cook Blair T Crewther Liam P Kilduff Scott Drawer Chris M Gaviglio 《Journal of the International Society of Sports Nutrition》2011,8(1):2
Background
We investigated the effects of sleep deprivation with or without acute supplementation of caffeine or creatine on the execution of a repeated rugby passing skill. 相似文献4.
ABSTRACT: BACKGROUND: in vitro and animal studies have demonstrated that Chlorella is a potent biological response modifier on immunity. However, there were no direct evidences for the effect of Chlorella supplementation on immune/inflammation response in healthy humans. Methods: This study was designed for an 8-week randomized, double-blinded, placebo-controlled trial: 5g of Chlorella (n=23) or Placebo (n=28) as form of tablets. Mainly, cytotoxic activities of Natural killer (NK) cells and serum concentrations of interferon-gamma, interleukin-1beta and interleukin-12 were measured. Results: After the 8-week, serum concentrations of interferon-gamma (p<0.05) and interleukin-1beta (p<0.001) significantly increased and that of interleukin-12 (p<0.1) tended to increase in the Chlorella group. The increments of these cytokines after the intervention were significantly bigger in the Chlorella group than those in the placebo group. In addition, NK cell activities (%) were significantly increased in Chlorella group, but not in Placebo group. The increments of NK cell activities (%) were also significantly bigger in the Chlorella group than the placebo group. Additionally, changed levels of NK cell activity were positively correlated with those of serum interleukin-1beta (r=0.280, p=0.047) and interferon-gamma (r=0.271, p<0.005). Signficantly positive correlations were also observed among the changed levels of serum cytokines; between interferon-gamma and interleukin-1beta (r=0.448, p<0.001), between interleukin-12 and interleukin-1beta (r=0.416, p=0.003) and between interleukin-12 and interferon-gamma (r=0.570, p<001). Conclusion: These results may suggest a beneficial immunostimulatory effect of short-term Chlorella supplementation which enhances the NK cell activity and produces interferon-gamma and interleukin-12 as well as interleukin-1beta, the Th-1 cell-induced cytokines in healthy people. 相似文献
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Courtenay Dunn-Lewis William J Kraemer Brian R Kupchak Neil A Kelly Brent A Creighton Hui-Ying Luk Kevin D Ballard Brett A Comstock Tunde K Szivak David R Hooper Craig R Denegar Jeff S Volek 《Nutrition journal》2011,10(1):1-10
Background
Evidence suggests that folate deficiency may be causatively linked to depressive symptoms. However, little is known on the status of use of folic acid and vitamin supplements among people with mental disorders. This study examined the prevalence and the likelihood of use of folic acid or vitamin supplements among adults with depression and anxiety in comparison to those without these conditions.Methods
Using data from 46, 119 participants (aged ≥ 18 years) in the 2006 Behavioral Risk Factor Surveillance System survey, we estimated the adjusted prevalence and odds ratios with 95% confidence intervals for taking folic acid and vitamin supplements among those with ever diagnosed depression (n = 8, 019), ever diagnosed anxiety (n = 5, 546) or elevated depressive symptoms (n = 3, 978, defined as having a depression severity score of ≥ 10 on the Patient Health Questionnaire-8 diagnostic algorithm).Results
Overall, women were more likely than men to take folic acid supplements 1-4 times/day (50.2% versus 38.7%, P < 0.001) and vitamin supplements (62.5% versus 49.8%, P < 0.001). After multivariate adjustment, men with ever diagnosed depression or anxiety were 42% and 83%, respectively, more likely to take folic acid supplements < 1 time/day; 44% and 39%, respectively, more likely to take folic acid supplements 1-4 times/day; and 40% and 46%, respectively, more likely to take vitamin supplements compared to men without these conditions (P < 0.05 for all comparisons). Women with ever diagnosed depression were 13% more likely to take folic acid supplements 1-4 times/day and 15% more likely to take vitamin supplements than women without this condition (P < 0.05 for both comparisons). Use of folic acid and vitamin supplements did not differ significantly by elevated depressive symptoms in either sex.Conclusion
The prevalence and the likelihood of taking folic acid and vitamin supplements varied substantially by a history of diagnosed depression among both men and women and by a history of diagnosed anxiety among men, but not by presence of elevated depressive symptoms in either sex. 相似文献6.
Yuta Komano Kazunori Shimada Hisashi Naito Kosuke Fukao Yoshihiko Ishihara Toshio Fujii Takeshi Kokubo Hiroyuki Daida 《Journal of the International Society of Sports Nutrition》2018,15(1):39
Background
Lactococcus lactis JCM 5805 (LC-Plasma) is a unique lactic acid bacteria (LAB) which activates plasmacytoid dendritic cells (pDC). We aimed to evaluate the effect of LC-Plasma on dendritic cell (DC) activity and subjective indices of upper respiratory tract infections (URTI) and fatigue in athletes under high intensity exercise.Methods
We conducted a randomized, placebo-controlled, double-blinded trial. Fifty-one male subjects belonging to a university sports club were randomized into placebo (n?=?25) and LC-Plasma (n?=?26) groups. Individuals ingested placebo capsules containing cornstarch or LC-Plasma capsules containing 100 billion cells of heat-killed LC-Plasma per day for 13 days. During the intervention period, subjects performed high intensity exercise according to their sports club training regime. Blood and saliva sampling were obtained at days 1 and 14, and physical conditions were recorded in a diary. We investigated expression of maturation markers on DCs, muscle damage and stress markers and used student’s t test adjusted by Bonferoni’s method for multiple comparison between groups. These data were presented as mean?±?SD. We also investigated cumulative days of symptoms regarding infections and fatigue and used Chi-square test for comparison between groups. These data were presented as cumulative number.Results
CD86 as maturation marker on pDC was significantly increased in the LC-Plasma group at day 14 (Placebo: 296?±?70 vs. LC-Plasma: 365?±?115; Mean Fluorescent Intensity; p?=?0.013). Cumulative days of URTI were significantly lower in the LC-Plasma group (Placebo: URTI positive 56, URTI negative 256 vs. LC-Plasma: URTI positive 39, URTI negative 299; days; p?=?0.028) and symptoms like sneeze or running nose were significantly lower in the LC-Plasma group (Placebo: Symptom positive 52, Symptom negative 258, vs. LC-Plasma: Symptom positive 36, Symptom negative 301; days; p?=?0.032). Moreover, the cumulative days of fatigue were significantly fewer in the LC-Plasma group (Placebo: Symptom positive 128, Symptom negative 182, vs. LC-Plasma: Symptom positive 110, Symptom negative 225; days; p?=?0.032). Markers of muscle damage and stress markers were not significantly different between groups.Conclusion
We consider that heat-killed LC-Plasma supplementation relieves morbidity and symptoms of URTI via activation of pDC and decreases fatigue accumulation during consecutive high intensity exercise in athletes. However, LC-Plasma ingestion did not affect markers of muscle damage and stress.Trial registration
UMIN-CTR, UMIN000020372. Registered 28 December 2015.7.
Stephen M Schmitz Jennifer E Hofheins Robert Lemieux 《Journal of the International Society of Sports Nutrition》2010,7(1):1-9
Background
Research has shown micronutrient deficiency to be scientifically linked to a higher risk of overweight/obesity and other dangerous and debilitating diseases. With more than two-thirds of the U.S. population overweight or obese, and research showing that one-third are on a diet at any given time, a need existed to determine whether current popular diet plans could protect followers from micronutrient deficiency by providing the minimum levels of 27 micronutrients, as determined by the U.S. Food and Drug Administrations (FDA) Reference Daily Intake (RDI) guidelines.Methods
Suggested daily menus from four popular diet plans (Atkins for Life diet, The South Beach Diet, the DASH diet, the DASH diet) were evaluated. Calorie and micronutrient content of each ingredient, in each meal, were determined by using food composition data from the U.S. Department of Agriculture Nutrient Database for Standard Reference. The results were evaluated for sufficiency and total calories and deficient micronutrients were identified. The diet plans that did not meet 100% sufficiency by RDI guidelines for each of the 27 micronutrients were re-analyzed; (1) to identify a micronutrient sufficient calorie intake for all 27 micronutrients, and (2) to identify a second micronutrient sufficient calorie intake when consistently low or nonexistent micronutrients were removed from the sufficiency requirement.Results
Analysis determined that each of the four popular diet plans failed to provide minimum RDI sufficiency for all 27 micronutrients analyzed. The four diet plans, on average, were found to be RDI sufficient in (11.75 ± 2.02; mean ± SEM) of the analyzed 27 micronutrients and contain (1748.25 ± 209.57) kcal. Further analysis of the four diets found that an average calorie intake of (27,575 ± 4660.72) would be required to achieve sufficiency in all 27 micronutrients. Six micronutrients (vitamin B7, vitamin D, vitamin E, chromium, iodine and molybdenum) were identified as consistently low or nonexistent in all four diet plans. These six micronutrients were removed from the sufficiency requirement and additional analysis of the four diets was conducted. It was determined that an average calorie content of (3,475 ± 543.81) would be required to reach 100% sufficiency in the remaining 21 micronutrients.Conclusion
These findings are significant and indicate that an individual following a popular diet plan as suggested, with food alone, has a high likelihood of becoming micronutrient deficient; a state shown to be scientifically linked to an increased risk for many dangerous and debilitating health conditions and diseases. 相似文献8.
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Paul H. Falcone Aaron C. Tribby Roxanne M. Vogel Jordan M. Joy Jordan R. Moon Chantelle A. Slayton Micah M. Henigman Joanne A. Lasrado Brandon J. Lewis Brenda A. Fonseca Kristin M. Nieman Kelli A. Herrlinger 《Journal of the International Society of Sports Nutrition》2018,15(1):58
Background
Proprietary spearmint extract (PSE) containing a minimum 14.5% rosmarinic acid and 24% total phenolic content, has evinced positive effects on cognition in individuals aged 50–70 with memory impairment after chronic supplementation. To address the growing interest in connecting mental and physical performance, the present study examined whether the nootropic effects of PSE translate into changes in reactive agility following daily supplementation with PSE.Methods
Utilizing a randomized, double-blind, placebo-controlled, parallel design, healthy, recreationally-active men and women (n?=?142) received 900?mg of PSE or placebo (PLA) daily for 90?days. Reactive agility, our primary outcome, was determined by measuring the number of hits and average reaction time (ART) on a Makoto Arena II, a 3600 audio-visual device that measures stationary, lateral, and multi-directional active choice reaction performance. Safety was evaluated using complete blood count, comprehensive metabolic panel, and blood lipids. Measurements were evaluated on days 7, 30, and 90 of supplementation.Results
An overall treatment effect (p?=?0.019) was evident for increased hits with PSE on the stationary test with footplates, with between group differences at Day 30 (PSE vs. PLA: 28.96?±?2.08 vs. 28.09?±?1.92 hits; p?=?0.040) and Day 90 (PSE vs. PLA: 28.42?±?2.54 vs. 27.02?±?3.55 hits; p?=?0.002). On the same task, ART improved (treatment effect, p?=?0.036) with PSE at Day 7 (PSE vs. PLA: 0.5896?±?0.060 vs. 0.6141?±?0.073?s; p?=?0.049) and Day 30 (PSE vs. PLA: 0.5811?±?0.068 vs. 0.6033?±?0.055?s; p?=?0.049). PSE also significantly increased hits (treatment effect, p?=?0.020) at Day 30 (PSE vs. PLA: 19.25?±?1.84 vs. 18.45?±?1.48 hits; p?=?0.007) and Day 90 (PSE vs. PLA: 19.39?±?1.90 vs. 18.66?±?1.64 hits; p?=?0.026) for the multi-directional test with footplates. Significant differences were not observed in the remaining Makoto tests. PSE was well tolerated as evidenced by no effects observed in the blood safety panels.Conclusions
The findings of the current study demonstrate that consumption of 900?mg of PSE improved specific measures of reactive agility in a young, active population.Trial registration
clinicaltrials.gov, NCT02518165. Registered August 7, 2015 – retrospectively registered.11.
Abbie E Smith Ashley A Walter Jennifer L Graef Kristina L Kendall Jordan R Moon Christopher M Lockwood David H Fukuda Travis W Beck Joel T Cramer Jeffrey R Stout 《Journal of the International Society of Sports Nutrition》2009,6(1):5
Background
Intermittent bouts of high-intensity exercise result in diminished stores of energy substrates, followed by an accumulation of metabolites, promoting chronic physiological adaptations. In addition, β-alanine has been accepted has an effective physiological hydrogen ion (H+) buffer. Concurrent high-intensity interval training (HIIT) and β-alanine supplementation may result in greater adaptations than HIIT alone. The purpose of the current study was to evaluate the effects of combining β-alanine supplementation with high-intensity interval training (HIIT) on endurance performance and aerobic metabolism in recreationally active college-aged men. 相似文献12.
The role of polyunsaturated fatty acid supplementation in intestinal inflammation and neonatal necrotizing enterocolitis 总被引:9,自引:0,他引:9
Dietary polyunsaturated fatty acid (PUFA) supplementation has been shown to reduce the incidence of necrotizing enterocolitis (NEC) in a recent randomized, controlled trial. These compounds are known to modulate the inflammatory cascade and to influence intestinal health in a variety of ways. Although the pathophysiology of NEC is not well understood, recent evidence suggests that platelet-activating factor (PAF) is a key endogenous mediator of intestinal necrosis in animals. Using a neonatal rat model of NEC that includes the key risk factors of asphyxia and formula feeding, we investigated the role of dietary PUFA supplementation on the incidence and pathophysiology of NEC. Our findings suggest that PUFA reduce the incidence of NEC by modulating PAF metabolism and endotoxin translocation. 相似文献
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Jennifer L Graef Abbie E Smith Kristina L Kendall David H Fukuda Jordan R Moon Travis W Beck Joel T Cramer Jeffrey R Stout 《Journal of the International Society of Sports Nutrition》2009,6(1):18-7
Background
High-intensity interval training has been shown to be a time-efficient way to induce physiological adaptations similar to those of traditional endurance training. Creatine supplementation may enhance high-intensity interval training, leading to even greater physiological adaptations. The purpose of this study was to determine the effects of high-intensity interval training (HIIT) and creatine supplementation on cardiorespiratory fitness and endurance performance (maximal oxygen consumption (VO2PEAK), time-to-exhaustion (VO2PEAKTTE), ventilatory threshold (VT), and total work done (TWD)) in college-aged men. 相似文献18.
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Augustin N Zeba Hermann Sorgho Noël Rouamba Issiaka Zongo Jeremie Rouamba Robert T Guiguemdë Davidson H Hamer Najat Mokhtar Jean-Bosco Ouedraogo 《Nutrition journal》2008,7(1):7
Background
Vitamin A and zinc are crucial for normal immune function, and may play a synergistic role for reducing the risk of infection including malaria caused by Plasmodium falciparum. 相似文献20.