Relative effectiveness of instructions, agreements, and reinforcement in behavioral contracts with alcoholics.

Evaluated the effects of the components of behavioral contracting on drinking in 40 chronic alcoholics. Ss were divided into 4 groups matched on age, education, length of problem drinking, and initial operant drinking responses. They were then exposed to 1 of the following conditions: (a) verbal instructions to limit alcohol consumption, (b) signed written agreement to limit consumption, (c) verbal instructions plus reinforcement for compliance, and (d) signed agreement plus reinforcement. Pre- and postoperant analog drinking sessions, in which leverpressing was reinforced with alcohol on a fixed ratio reinforcement schedule, served to assess effects of the experimental conditions. Results indicate that while instructions and signed agreements had limited influence on drinking, both groups receiving reinforcement for compliance significantly decreased their operant drinking. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Drink less or drink slower: The effects of instruction on alcohol consumption and drinking control strategy use.

Brief alcohol interventions often involve recommendations to use drinking control strategies. However, little is known about the functional effect of these strategies on alcohol use. This prospective study employed an experimental design to evaluate the relationship between strategy use and alcohol consumption. The differential effects of instructions to increase the use of strategies or to reduce alcohol consumption were compared to self-monitoring (SM) only. Undergraduate drinkers were randomized into 3 conditions: SM plus strategy increase (SI; n = 61), SM plus alcohol reduction (AR; n = 60), and SM control (SM; n = 56). Participants in the AR group reduced their alcohol use over 2 weeks, while those in the SI group did not drink less. Participants in the SI group increased strategy use over time, whereas the AR group increased use of some strategies but not others. These results indicate that increasing use of drinking control strategies does not necessarily result in reduced drinking. Furthermore, all strategies are not equal in their association with alcohol consumption; if the goal is alcohol reduction, type of strategy recommended may be important. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cost-benefit analysis of the Program for Early Screening of Cervico-uterine Cancer]

Initiation of alcohol drinking using the sucrose-substitution procedure was studied in inbred Lewis rats. One group of animals was initiated to self-administer alcohol prior to being placed in the continuous-access condition, whereas the second group of animals did not undergo initiation. During the continuous-access period, the animals were housed in operant chambers where they had continuous access to alcohol (10% v/v), food, and water during daily 23-h experimental sessions. After 5 weeks of baseline conditions, the response, requirement for food was increased over weeks. This was followed by weekly increases in the ethanol response requirement with the food response requirement returned to baseline conditions. In the continuous-access condition, both groups consumed similar amounts of alcohol by the end of the 4-week baseline period and showed similar numbers of dippers presented per alcohol bout and number of alcohol bouts per day. During the food response requirement manipulation, alcohol consumption increased for both groups but intake increased significantly more for the noninitiated group. The difference between groups was accounted for by a larger number of alcohol drinking bouts per day for the noninitiated group. Alcohol consumption decreased at each increase in ethanol reinforcement response requirement for both groups. Alcohol-reinforced responding per session increased for the noninitiated animals but remained unchanged for the initiated group during this condition. Responding increased substantially for both groups when the alcohol reinforcement response requirement was returned to baseline conditions. These results suggest that alcohol may serve more as a food source for noninitiated animals during the food reinforcement manipulation and that initiation may result in more resistance to change during the alcohol reinforcement manipulation. These data show that the type of initial exposure to alcohol can impact future drinking patterns.     

Comparison of alcohol-preferring and nonpreferring selectively bred rat lines. I. Ethanol initiation and limited access operant self-administration

Several lines of alcohol-preferring and alcohol-nonpreferring rats have been developed using selective breeding based on 24-hr homecage ethanol consumption. However, it remains unclear if the selection based on two-bottle choice resulted in similar ethanol self-administration when measured using an operant procedure. In this paper, we compare our previous work using alcohol-accepting (AA) and alcohol-nonaccepting (ANA) rats with data obtained using the identical procedures in the (P) and (NP) rat lines, and both replicate lines of the high alcohol drinking (HAD1 and HAD2) and low alcohol drinking (LAD1 and LAD2) lines. All rats from each line were initiated to self-administer 10% ethanol using the sucrose fading procedure. After initiation, increasing concentrations of ethanol up to 30% ethanol were tested. The results indicated that only in the LAD1 and LAD2 lines was ethanol presentation not able to maintain lever pressing after initiation. Compared with the AA line, the P, HAD1, HAD2, and NP lines all self-administered more ethanol in the operant paradigm after initiation. The ANA line self-administered less ethanol than the AA line, but more than the LAD lines. Correlational analysis of homecage consumption with operant ethanol self-administration suggested that approximately 62% of the genetic variance in operant self-administration resulted from genes selected for the homecage drinking. At the same time, it was clear that there were genetic influences on operant self-administration that were not selected for by homecage ethanol drinking.     

Factors influencing the temporal relationship between alcohol consumption and experiences with aggression among college women.

The authors assessed temporal relationships among alcohol use, aggression, and mood using daily data from 179 college women. Participants called an interactive voice response system over an 8-week period. The odds of experiencing verbal, sexual, and physical aggression (odd ratios = 2.25, 19.44, and 11.84, respectively) were significantly higher on heavy drinking days (M = 7.46 drinks) compared to nondrinking days. Both a history of victimization and greater psychological symptom severity influenced the odds of involvement in verbal aggression. The odds of alcohol consumption were 3 times higher during the 24 hr following verbal aggression compared with days in which verbal aggression did not occur. On the day immediately following involvement in either verbal or physical aggression, positive mood decreased and negative mood increased. During the week (2-7 days) following sexual aggression, women's positive mood was decreased. These findings reinforce the need for interventions aimed at reducing heavy episodic drinking on college campuses. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Long-term self-intravenous "drinking" in the rat.

Results of a series of experiments show that male Wistar albino rats, when water was available only by intravenous self-injection, learned to rehydrate by pressing a lever even after desalivation and for periods up to 90 days. It appears that hydromineral regulation was occurring about a new, lower set point for body fluid content which was necessary for the onset and maintenance of intravenous "drinking." The regulatory nature of the operant was confirmed by appropriate modulation of operant rate to amount of reinforcement per leverpress and in tonicity of self-injected fluid. There seemed to be some "motivational deficits," and these Ss did not respond for intravenous water as the oral controls did when challenged with traditional intra- and extracellular thirst stimuli. More complex stimuli (e.g., heat and salty food) led to compensatory responding. While interoceptors alone seemed capable of eliciting the defense of a homeostatic hydromineral balance, the control over the operant was less precise than for normal oral drinking. (57 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The Morning After: Limit Violations and the Self-Regulation of Alcohol Consumption.

The authors examined whether the reciprocal relationship between alcohol consumption and distress unfolded over time in 2 samples of social drinkers. Participants monitored their alcohol intake and their cognitive and emotional responses to that drinking on hand-held computers. On mornings after drinking, those who had violated their self-imposed limits the day before reported more guilt, even after controlling for acute negative symptoms of drinking and amount consumed. Reciprocally, guilt led to poorer self-regulation of alcohol intake: Greater distress over alcohol consumption was linked to more intake, intoxication, and more limit violations. Individual differences moderated the relationships among limit violations, distress, and drinking. Consistent with the limit violation effect, violating a limit produced distress over consumption among social drinkers, and they responded to that distress by drinking more. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Behavioral analysis of chronic alcoholism in four women

Observed the behavior of 4 female 38-50 yr old alcoholics over a 22-day period at the Alcoholic Behavior Research Laboratory, Rutgers University. A 12-day drinking period was preceded by a 6-day predrinking baseline assessment period and followed by a 4-day postdrinking withdrawal phase. Points earned for operant responding at a button-pressing task were spent to purchase alcohol, relief from programmed social isolation, or both during specified periods. Ss emitted high operant rates during predrinking, largely to accumulate socialization points. Operant rate declined when alcohol became available. When Ss resumed operant responding, they tended to work for and spend about the same number of alcohol points each day. Ss resumed working for socialization points when they ran out of them; they continued to earn these points into the postdrinking period. Ss consumed consistent amounts of alcohol each day in a cyclic pattern, almost always reaching their highest blood alcohol level at the midnight reading. Drink preference, sip magnitude, and consumption time resembled more closely those behaviors reported for male social drinkers than for male alcoholics. Ss reported generally improved affect when drinking began. No changes in psychopathology were noted during drinking. (22 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Schizophrenia as a "put-on."

Refutes findings of L. S. Levitz and L. P. Ullman (see43:4) by citing evidence that schizophrenics are unresponsive to social instructions and verbal reinforcement, and differ from normals in being unable to turn off disturbed thinking. The importance of determining reinforcement contingencies and the mechanisms responsible for schizophrenic thinking in order to modify central schizophrenic symptoms is emphasized. (25 ref.) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Verbal operant conditioning of hospitalized psychiatric patients.

In Exp. I, 81 male psychiatric patients were divided into 9 subgroups according to age and length of hospitalization. Plural nouns were reinforced by positive verbal feedback. Results were: (1) least chronic Ss increased their operant rates; (2) most chronic Ss did not; and (3) there was significant interaction with respect to age and chronicity. In Exp. II, 60 schizophrenics were divided into 6 subgroups with respect to length of hospitalization and mode of reinforcement, i.e., verbal, primary, or combination. Acute-type schizophrenics responded positively to all types of reinforcement. Chronics responded only to primary reinforcement and to the combination procedure. Mode of reinforcement was a significant variable affecting operant rate. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The effect of negative verbal cues upon verbal behavior.

Research which investigated the capacity to modify behavior, starting from the framework of Skinner's operant conditioning paradigm and utilizing verbal behavior, was found to have primarily explored the effect of positive secondary reinforcement. The present investigation explored the effect of a negative verbal cue presented under different schedules of reinforcement upon verbal behavior. Ss (male VA psychiatric patients) responded to projective techniques. The E varied the frequency of negative verbal reinforcement defined as "unh unh." The hypothesis that such a negative reinforcement would depress verbal behavior was substantiated, with a periodic schedule of reinforcement being more effective. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol intake and cognitive abilities in old age: The Lothian Birth Cohort 1936 study.

Objective: Moderate alcohol consumption has been associated with better cognitive performance in late adulthood, possibly by improving vascular health. Few studies have examined the potentially confounding roles of prior cognitive ability and social class in this relationship. Method: Participants were 922 healthy adults about 70 years old in the Lothian Birth Cohort 1936 study, for whom there are IQ data from age 11. Alcohol consumption was obtained by self-report questionnaire. Cognitive outcome measures included general cognitive ability, speed of information processing, memory, and verbal ability. Results: Moderate to substantial drinking (>2 units/day) was associated with better performance on cognitive tests than low-level drinking (≤2 units/day) or nondrinking in men and women. After adjusting for childhood IQ and adult social class, most of these associations were removed or substantially attenuated. After full adjustment, a small, positive association remained between overall alcohol intake and memory (women and men) and verbal ability (women only). Women's overall alcohol intake was derived almost exclusively from wine. In men, effects differed according to beverage type: wine and sherry–port consumption was associated with better verbal ability, but beer was associated with a poorer verbal ability and spirits intake was associated with better memory. Conclusions: Prior intelligence and socioeconomic status influence both amount and type of alcohol intake and may partly explain the link between alcohol intake and improved cognitive performance at age 70. Alcohol consumption was found to make a small, independent contribution to memory performance and verbal ability, but these findings' clinical significance is uncertain. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

The alcohol deprivation effect in the alcohol-preferring P rat under free-drinking and operant access conditions

The alcohol-deprivation effect (ADE) was examined under 4-hr operant and 24-hr free-choice alcohol access in the alcohol-preferring (P) rat after deprivation intervals from 2 to 4 weeks. Results indicated that adult male P rats responding for 6 weeks on a concurrent FR-5/FR-1 schedule of reinforcement for alcohol and water, respectively, and then deprived of alcohol for 2 weeks, demonstrated a 40% increase in alcohol responding during the first 60 min of alcohol reinstatement. The alcohol deprivation effect was temporary, however, as responding did not differ from baseline levels on the second day of reinstatement. In a second experiment, weanling male and female P rats received 7 weeks of continuous access to alcohol, beginning at 21 days of age, and were then deprived of alcohol for 4 weeks. On the first day of alcohol reinstatement, P rats exhibited a 40% to 45% increase from baseline alcohol drinking levels, with alcohol intake returning to baseline levels by the 3rd day of reinstatement. Although alcohol intake was higher in females than in males when adjustment was made for body weight, there were no gender differences in the magnitude of the alcohol deprivation effect. Taken together, these results indicate that the ADE is a long-lasting phenomenon that occurs under both operant and continuous access conditions in the P rat, and thus these rats may be useful models for the study of factors involved in relapse of alcohol drinking.     

Influence of naltrexone on cue-elicited craving among hazardous drinkers: The moderational role of positive outcome expectancies.

This study was designed to elucidate mechanisms by which naltrexone (NTX) influences drinking among hazardous drinkers. Thirty-six hazardous drinkers received 50 mg NTX or placebo on 2 separate occasions before participation in a taste test procedure with low-alcohol beer. Urges to drink before consumption, beer volume consumed, and perceived stimulation and sedation after consumption were assessed. Although NTX did not influence beer consumption, hazardous drinkers who reported high positive reinforcement expectancies rated their urges to drink as significantly lower when they were on NTX compared with placebo. Positive outcome expectancies also moderated the effects of NTX on subjective reports of stimulation following drinking. These findings suggest that naltrexone may be particularly effective at reducing alcohol cue-elicited positive reinforcement for those with high positive alcohol outcome expectancies. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Review of Outpatient behavior therapy: A clinical guide.

Reviews the book, Outpatient behavior therapy: A clinical guide edited by Michel Hersen. In the preface to the book, Hersen indicates that very few texts have incorporated a practical, how-to-do-it flavor for the treatment of a wide variety of patients. This book is designed to fill this gap. The book has three parts: general issues, adult disorders, and childhood disorders. This book could be a valuable, practical reference for psychotherapists who wish to utilize behavior therapy procedures with outpatient clients whose disorders fall within the scope of the book's chapters. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Examining the role of drinking motives in college student alcohol use and problems.

A motivational model of alcohol involvement (M. L. Cooper, M. R. Frone, M. Russell, & P. Mudar, 1995) was replicated and extended by incorporating social antecedents and motives and by testing this model cross-sectionally and longitudinally in a sample of college students. Participants (N = 388) completed a questionnaire battery assessing alcohol use and problems, alcohol expectancies, sensation seeking, negative affect, social influences, and drinking motives. Associations among psychosocial antecedents, drinking motives, and alcohol involvement differed from those found by M. L. Cooper et al. (1995). These findings point to the importance of social influences and of positive reinforcement motives but not to the centrality of drinking motives in this population. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Alcohol and depression: Effects on mood and biased processing of self-relevant information.

Alcohol's effects on mood and processing of self-relevant information were studied in a sample of 57 college students (39 men and 18 women). Participants were blocked on level of depression and were randomly assigned to alcohol or placebo conditions. After beverage consumption, participants processed trait adjectives under self-relevant and semantic-processing instructions. Results showed that biased processing of depressed content adjectives by depressed participants under placebo conditions was reversed after consuming alcohol. Further, reduced recall of depressed-content, self-relevant information after alcohol consumption was significantly related to alcohol-enhanced mood in depressed participants. Results are discussed in relation to mechanisms of reinforcement that may link the coexistence of alcohol abuse and affective disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Further validation of a cigarette purchase task for assessing the relative reinforcing efficacy of nicotine in college smokers.

The authors sought to further validate a cigarette purchase task (CPT), a self-report analogue of a progressive-ratio operant schedule, for the assessment of the relative reinforcing efficacy (RRE) of nicotine in smokers. The measure was assessed in terms of its correspondence to typically observed operant behavior, convergent validity, and divergent validity. Participants were 33 individuals (58% male, age M = 19.30 years) who smoked at least weekly (M = 5.31 cigarettes/day) and underwent a single assessment session. Data from the CPT exhibited the predicted inverse relationship between consumption and price, the predicted relationship between consumption and expenditure, and a heterogeneous pattern of interrelationships among the indices of reinforcement. In addition, 2 indices from the measure, intensity of demand and maximum expenditure for cigarettes, exhibited robust convergent and divergent validity. Although this is an incipient research area and the current study used a relatively small sample, these findings support the validity of a CPT as a time- and cost-efficient method for assessing nicotine reinforcement. Theoretical implications of the findings, limitations, and future directions are also discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The influence of alcohol expectancy priming and mood manipulation on subsequent alcohol consumption.

Studies showing that verbal priming can implicitly affect alcohol consumption have been used to support cognitive models of expectancies. However, because expectancy words reflect affective states as well as drinking outcomes, mediation through an affective pathway remains theoretically plausible (i.e., such words inadvertently may affect mood, which in turn influences drinking). The primary pathway was identified (and expectancy theory was tested) by comparing memory priming (using alcohol expectancy or neutral words) with mood induction (using positive or neutral music); an unrelated experiment paradigm allowed the priming manipulation to implicitly affect drinking. Men in the alcohol priming group drank significantly more than men in each of the other conditions, and, consistent with theory, men with histories of heavier drinking drank the most when primed with alcohol expectancies, indicating that expectancies can function as automatic memory processes. (PsycINFO Database Record (c) 2010 APA, all rights reserved)