基于深度神经网络的个性化睡眠癫痫发作预测

现有癫痫发作预测方法存在精度较低、错误报警率较高、癫痫患者睡眠脑电特异性、致痫灶位置和类型不同导致脑电信号存在差异的问题.文中提出基于深度神经网络的个性化睡眠癫痫发作预测方法,帮助医生和患者采取及时有效的治疗措施,降低患者患并发症和猝死的概率.对原始脑电信号滤波和分段以去除噪声,保证短时间内触发警报,利用离散小波变换分解信号并提取统计特征表征脑电信号时频特征.再应用双向长短期记忆网络挖掘最具鉴别能力的特征并结合留一法分类,经过决策过程优化得到预测结果.在不同频带限制条件下的实验表明,与睡眠癫痫相关的δ频带信号是影响发作预测性能的重要因素.相比现有睡眠癫痫预测方法,文中方法性能较优.     

Automatic classification of sleep stages based on the time-frequency image of EEG signals

In this paper, a new method for automatic sleep stage classification based on time-frequency image (TFI) of electroencephalogram (EEG) signals is proposed. Automatic classification of sleep stages is an important part for diagnosis and treatment of sleep disorders. The smoothed pseudo Wigner–Ville distribution (SPWVD) based time-frequency representation (TFR) of EEG signal has been used to obtain the time-frequency image (TFI). The segmentation of TFI has been performed based on the frequency-bands of the rhythms of EEG signals. The features derived from the histogram of segmented TFI have been used as an input feature set to multiclass least squares support vector machines (MC-LS-SVM) together with the radial basis function (RBF), Mexican hat wavelet, and Morlet wavelet kernel functions for automatic classification of sleep stages from EEG signals. The experimental results are presented to show the effectiveness of the proposed method for classification of sleep stages from EEG signals.     

Classification of sleep stages based on LSTAR model

Sleep study is very important in the health since sleep disorders affect the productivity of individuals. One of the important topics in sleep research is the classification of sleep stages using the electroencephalogram (EEG) signal. Electrical activities of brain are measured by EEG signal in the laboratory. In real-world environments, EEG signal is also used in portable monitoring devices to analyze sleep. In this study, we propose an efficient method for classification of sleep stages. EEG signals are examined by a new model from autoregressive (AR) family, namely logistic smooth transition autoregressive (LSTAR) to study sleep process. In contrast to the AR model, LSTAR is a non-linear one; therefore, it is suitable for modeling non-linear signals such as EEG. In the current research, at first, each 30-second epoch of EEG signal is decomposed into the time-frequency sub-bands using the double-density dual-tree discrete wavelet transform (D3TDWT). In the second step, LSTAR model is used for feature extraction from each sub-band. Next, the dimension of feature vector is reduced by tensor locality preserving projection (tensor LPP) method, and then the obtained features are given to classifier to determine the stage of each epoch based on the number of considered classes. After classifying sleep stages, some misclassified epochs can be corrected according to the smoothing rule. We consider different classifiers and evaluate their performance. The results indicate the efficiency of the proposed method in comparison with the recently introduced methods in terms of accuracy and Kappa coefficient.     

Classification of sleep stages using class-dependent sequential feature selection and artificial neural network

Several studies have been conducted for automatic classification of sleep stages to ease time-consuming manual scoring process that can involve a high degree of experience and subjectivity. But none of them has found a practical usage in medical area so far because of their under acceptable success rates. In this study, a different classification scheme is proposed to increase the success rate in automatic sleep stage scoring in which sleep stages were classified as Awake, Non-REM1, Non-REM2, Non-REM3 and REM stages. Using EEG, EMG and EOG recordings of five healthy subjects, a modified version of sequential feature selection method was applied to the sleep epochs in class by class basis and different artificial neural network (ANN) architectures were trained for each class. That is to say, sleep stages were classified with five ANN architectures each of which uses different features and different network parameters for classification. The highest classification accuracy was obtained for REM sleep as 95.13 % in addition to the lowest classification accuracy of 86.42 % for Non-REM3 sleep. The overall accuracy, on the other hand, was recorded as 90.93 %, which is a comparatively good result when the other studies using all stages are taken into account.     

ADAPTIVE NEURO-FUZZY INFERENCE SYSTEM FOR AUTOMATIC SLEEP MULTISTAGE LEVEL SCORING EMPLOYING EEG,EOG, AND EMG EXTRACTED FEATURES

A new system for sleep multistage level scoring by employing extracted features from twenty five polysomnographic recording is presented. For the new system, an adaptive neuro-fuzzy inference system (ANFIS) is developed for each sleep stage. Initially, three types of electrophysiological signals including electroencephalogram (EEG), electrooculogram (EOG), and electromyogram (EMG) were collected from twenty five healthy subjects. The input pattern used for training the ANFIS subsystem is a set of extracted features based on the entropy measure which characterize the recorded signals. Finally an output selection subsystem is utilized to provide the appropriate sleep stage according to the ANFIS stage subsystems outputs. The developed system was able to provide an acceptable estimation for six sleep stages with an average accuracy of about 76.43% which confirmed its ability for multistage sleep level scoring based on the extracted features from the EEG, EOG and EMG signals compared to other approaches.     

EEG rhythm/channel selection for fuzzy rule-based alertness state characterization

The aim of the paper is to automatically select the optimal EEG rhythm/channel combinations capable of classifying human alertness states. Four alertness states were considered, namely ‘engaged’, ‘calm’, ‘drowsy’ and ‘asleep’. The features used in the automatic selection are the energies associated with the conventional rhythms, \(\delta , \theta , \alpha , \beta\) and \(\gamma\), extracted from overlapping windows of the different EEG channels. The selection process consists of two stages. In the first stage, the optimal brain regions, represented by sets of EEG channels, are selected using a simple search technique based on support vector machine (SVM), extreme learning machine (ELM) and LDA classifiers. In the second stage, a fuzzy rule-based alertness classification system (FRBACS) is used to identify, from the previously selected EEG channels, the optimal features and their supports. The IF–THEN rules used in FRBACS are constructed using a novel differential evolution-based search algorithm particularly designed for this task. Each alertness state is represented by a set of IF–THEN rules whose antecedent parts contain EEG rhythm/channel combination. The selected spatio-frequency features were found to be good indicators of the different alertness states, as judged by the classification performance of the FRBACS that was found to be comparable to those of the SVM, ELM and LDA classifiers. Moreover, the proposed classification system has the advantage of revealing simple and easy to interpret decision rules associated with each of the alertness states.

     

基于经验模态分解和SVM的脑电信号分类方法

脑电信号的非线性、非平稳性造成对运动想象脑电信号的分类识别存在特征提取困难、可区分性低以及分类识别性能差等问题。本文提出一种基于经验模态分解(Empirical Mode Decomposition, EMD)和支撑向量机(Support Vector Machine, SVM)的运动想象脑电信号分类方法,充分利用EMD算法在处理非线性、非平稳信号的自适应性以及SVM在小样本条件的高识别性能和强泛化能力。首先利用EMD算法将C3、C4导联信号分解为一系列本征模函数(Intrinsic Mode Function, IMF),然后从IMF的信息和能量等维度提取特征将脑电信号转换至区分性更强的特征域,最后利用SVM进行分类识别。采用国际BCI竞赛2003中的Graz数据进行验证,所提方法可以得到94.6%的正确识别率,为在线脑-机接口系统的研究提供了新的思路。     

基于CNN-BiLSTM的自动睡眠分期算法

睡眠分期是睡眠数据分析的基础,针对目前睡眠分期存在的依赖人工提取、人工判别效率低、自动睡眠分期准确率不高等问题,本文研究模型是基于卷积神经网络和双向长短时记忆神经网络2个深度学习神经网络相结合的,利用脑电信号来进行自动睡眠分期的模型方法.算法能提取得到原始脑电信号的梅尔频谱,利用卷积神经网络和双向长短时记忆神经网络进行...     

Clustering technique-based least square support vector machine for EEG signal classification

This paper presents a new approach called clustering technique-based least square support vector machine (CT-LS-SVM) for the classification of EEG signals. Decision making is performed in two stages. In the first stage, clustering technique (CT) has been used to extract representative features of EEG data. In the second stage, least square support vector machine (LS-SVM) is applied to the extracted features to classify two-class EEG signals. To demonstrate the effectiveness of the proposed method, several experiments have been conducted on three publicly available benchmark databases, one for epileptic EEG data, one for mental imagery tasks EEG data and another one for motor imagery EEG data. Our proposed approach achieves an average sensitivity, specificity and classification accuracy of 94.92%, 93.44% and 94.18%, respectively, for the epileptic EEG data; 83.98%, 84.37% and 84.17% respectively, for the motor imagery EEG data; and 64.61%, 58.77% and 61.69%, respectively, for the mental imagery tasks EEG data. The performance of the CT-LS-SVM algorithm is compared in terms of classification accuracy and execution (running) time with our previous study where simple random sampling with a least square support vector machine (SRS-LS-SVM) was employed for EEG signal classification. We also compare the proposed method with other existing methods in the literature for the three databases. The experimental results show that the proposed algorithm can produce a better classification rate than the previous reported methods and takes much less execution time compared to the SRS-LS-SVM technique. The research findings in this paper indicate that the proposed approach is very efficient for classification of two-class EEG signals.     

基于注意力机制的多分支LSTM心理负荷评估模型

充分获取脑电信号的有效特征已成为心理负荷评估亟待解决的问题.提出一种多分支LSTM和注意力机制相结合的多分类网络框架.首先,此网络在对脑电信号做切片处理后,采用多分支LSTM网络提取切片中的时间特征;然后,利用注意力机制对所提取的时间特征进行权重参数优化;最后,通过softmax层输出心理负荷评估结果.通过消融实验和对比实验对模型进行验证.结果 表明,此网络无论在二分类任务还是多分类任务中的表现均优于现有先进网络.     

一种基于个人身份认证的正面人脸识别算法

利用小波分解提取人脸特征技术和支持向量机 (SVM)分类模型 ,提出了一种基于个人身份认证的正面人脸识别算法 (或称为人脸认证方法 ) .针对 M个用户的人脸认证算法包括二个阶段 :(1)训练阶段 :使用小波分解方法对脸像训练集中的人脸图象进行特征提取 ,并用所提取的人脸特征向量训练 M个 SVM(对应 M个用户 ) ;(2 )认证阶段 :先由待认证者所声称的用户身份 (姓名或密码等 )确定对应的一训练好的 SVM,然后用这一 SVM对小波分解方法提取的待认证人的脸像特征向量进行分类 ,分类结果将显示待认证人所声称的身份是否真实 .利用 ORL人脸图象库对该算法的实验测试结果 ,以及与径向基函数神经网络作为分类器时的实验结果比较表明了该算法性能的优越性     

基于稀疏组lasso-granger因果关系特征的脑电信号情感识别

针对目前基于单一脑区功能性网络层面的特征提取,文中提出稀疏组lasso-granger因果关系方法.首先从效应性脑网络层面提取不同脑区之间的因果关系作为脑电特征,分别提取受试者α,β,γ脑电波段的granger因果特征值.然后引用稀疏组lasso算法对获取的granger因果特征值进行特征筛选,获得高相关性特征子集作为情感分类特征.最后使用SVM分类器进行情感分类.此外,为了减少计算时间复杂度,使用过滤特征选择(ReliefF)算法,选取有效的脑电信号通道.实验表明,文中方法在Valence-Arousal二维情感模型上获得较高的平均情感分类准确率,分类效果优于对比的脑电特征,提取的情感脑电特征可以有效识别受试者的不同情感状态.     

Intensity-based statistical features for classification of lungs CT scan nodules using artificial intelligence techniques

A computer-aided diagnostic (CAD) system for effective and accurate pulmonary nodule detection is required to detect the nodules at early stage. This paper proposed a novel technique to detect and classify pulmonary nodules based on statistical features for intensity values using support vector machine (SVM). The significance of the proposed technique is, it uses the nodules features in 2D & 3D and also SVM for the classification that is good to classify the nodules extracted from the image. The lung volume is extracted from Lung CT using thresholding, background removal, hole-filling and contour correction of lung lobe. The candidate nodules are extracted and pruned using the rules based on ground truth of nodules. The statistical features for intensity values are extracted from candidate nodules. The nodule data are up-samples to reduce the biasness. The classifier SVM is trained using data samples. The efficiency of proposed CAD system is tested and evaluated using Lung Image Consortium Database (LIDC) that is standard data-set used in CAD Systems for Lungs Nodule classification. The results obtained from proposed CAD system are good as compare to previous CAD systems. The sensitivity of 96.31% is achieved in the proposed CAD system.     

A novel Parkinson’s Disease Diagnosis Index using higher-order spectra features in EEG signals

Higher-order spectra (HOS) is an efficient feature extraction method used in various biomedical applications such as stages of sleep, epilepsy detection, cardiac abnormalities, and affective computing. The motive of this work was to explore the application of HOS for an automated diagnosis of Parkinson’s disease (PD) using electroencephalography (EEG) signals. Resting-state EEG signals collected from 20 PD patients with medication and 20 age-matched normal subjects were used in this study. HOS bispectrum features were extracted from the EEG signals. The obtained features were ranked using t value, and highly ranked features were used in order to develop the PD Diagnosis Index (PDDI). The PDDI is a single value, which can discriminate the two classes. Also, the ranked features were fed one by one to the various classifiers, namely decision tree (DT), fuzzy K-nearest neighbor (FKNN), K-nearest neighbor (KNN), naive bayes (NB), probabilistic neural network (PNN), and support vector machine (SVM), to choose the best classifier using minimum number of features. We have obtained an optimum mean classification accuracy of 99.62%, mean sensitivity and specificity of 100.00 and 99.25%, respectively, using the SVM classifier. The proposed PDDI can aid the clinicians in their diagnosis and help to test the efficacy of drugs.

     

Wavelet-based envelope features with automatic EOG artifact removal: Application to single-trial EEG data

In this study, we propose an analysis system for single-trial classification of electroencephalogram (EEG) data. Combined with automatic EOG artifact removal and wavelet-based amplitude modulation (AM) features, the support vector machine (SVM) classifier is applied to the classification of left finger lifting and resting. Automatic EOG artifact removal is proposed to eliminate the EOG artifacts automatically by means of independent component analysis (ICA) and correlation coefficient. The features are then extracted from the discrete wavelet transform (DWT) data by the AM method. Finally, the SVM is used for the discriminant of wavelet-based AM features. Compared with EEG data without EOG artifact removal, band power features and LDA classifier, the proposed system achieves promising results in classification accuracy.     

基于分层聚类及重采样的大规模数据分类

针对大规模数据的分类问题,将监督学习与无监督学习结合起来,提出了一种基于分层聚类和重采样技术的支持向量机(SVM)分类方法。该方法首先利用无监督学习算法中的k-means聚类分析技术将数据集划分成不同的子集,然后对各个子集进行逐类聚类,分别选出各类中心邻域内的样本点,构成最终的训练集,最后利用支持向量机对所选择的最具代表样本点进行训练建模。实验表明,所提方法可以大幅度降低支持向量机的学习代价,其分类精度比随机欠采样更优,而且可以达到采用完整数据集训练所得的结果     

基于混合神经网络的脑电时空特征情感分类

提出一种脑电图（electroencephalograph,简称EEG）数据表示方法,将一维链式EEG向量序列转换成二维网状矩阵序列,使矩阵结构与EEG电极位置的脑区分布相对应,以此来更好地表示物理上多个相邻电极EEG信号之间的空间相关性.再应用滑动窗将二维矩阵序列分成一个个等长的时间片段,作为新的融合了EEG时空相关性的数据表示.还提出了级联卷积-循环神经网络（CASC_CNN_LSTM）与级联卷积-卷积神经网络（CASC_CNN_CNN）这两种混合深度学习模型,二者都通过CNN卷积神经网络从转换的二维网状EEG数据表示中捕获物理上相邻脑电信号之间的空间相关性,而前者通过LSTM循环神经网络学习EEG数据流在时序上的依赖关系,后者则通过CNN卷积神经网络挖掘局部时间与空间更深层的相关判别性特征,从而精确识别脑电信号中包含的情感类别.在大规模脑电数据集DEAP上进行被试内效价维度上两类情感分类实验,结果显示,所提出的CASC_CNN_LSTM和CASC_CNN_CNN网络在二维网状EEG时空特征上的平均分类准确率分别达到93.15%和92.37%,均高于基准模型和现有最新方法的性能,表明该模型有效提高了EEG情感识别的准确率和鲁棒性,可以有效地应用到基于EEG的情感分类与识别相关应用中.     

Performance of hidden Markov model and dynamic Bayesian network classifiers on handwritten Arabic word recognition

This paper presents a comparative study of two machine learning techniques for recognizing handwritten Arabic words, where hidden Markov models (HMMs) and dynamic Bayesian networks (DBNs) were evaluated. The work proposed is divided into three stages, namely preprocessing, feature extraction and classification. Preprocessing includes baseline estimation and normalization as well as segmentation. In the second stage, features are extracted from each of the normalized words, where a set of new features for handwritten Arabic words is proposed, based on a sliding window approach moving across the mirrored word image. The third stage is for classification and recognition, where machine learning is applied using HMMs and DBNs. In order to validate the techniques, extensive experiments were conducted using the IFN/ENIT database which contains 32,492 Arabic words. Experimental results and quantitative evaluations showed that HMM outperforms DBN in terms of higher recognition rate and lower complexity.     

Automatic recognition of sleep spindles in EEG via radial basis support vector machine based on a modified feature selection algorithm

This paper presents an application of a radial basis support vector machine (RB-SVM) to the recognition of the sleep spindles (SSs) in electroencephalographic (EEG) signal. The proposed system comprises of two stages. In the first stage, for feature extraction, a set of raw amplitude values, a set of discrete cosine transform (DCT) coefficients, a set of discrete wavelet transform (DWT) approximation coefficients and a set of adaptive autoregressive (AAR) parameters are calculated and extracted from signals separately as four different sets of feature vectors. Thus, four different feature vectors for the same data are comparatively examined. In the second stage, these features are then selected by a modified adaptive feature selection method based on sensitivity analysis, which mainly supports input dimension reduction via selecting the most significant feature elements. Then, the feature vectors are classified by a support vector machine (SVM) classifier, which is relatively new and powerful technique for solving supervised binary classification problems due to its generalization ability. Visual evaluation, by two electroencephalographers (EEGers), of 19 channel EEG records of six subjects showed that the best performance is obtained with an RB-SVM providing an average sensitivity of 97.7%, an average specificity of 97.4% and an average accuracy of 97.5%.     

基于周期分割的睡眠自动分期研究

为实现高效的自动睡眠分期，提出一种基于周期分割的时域信号处理方法，采用合并增减序列方法对三个通道多导睡眠图记录（2路脑电，1路眼电）进行周期分割，根据信号波形的周期标记睡眠各期的特征波形，提取特征波形在每一帧数据的时长占比与平均幅值作为特征。双向长短时记忆网络（Bi-directional Long Short-Term Memory，Bi-LSTM）作为分类器，解决传统机器学习方法无法利用睡眠数据时间上下文信息的缺点。对42?699个样本使用交叉验证方法得到了84.8%的平均准确率，实验结果表明合并增减序列方法可以降低脑电信号分析的复杂度，是一种有效的时域信号处理方法，双向长短时记忆网络可以有效提高睡眠分期准确率，具有良好的应用前景。