High-strength superparamagnetic composite fibers

The polymer composites of magnetic nanoparticles can be possibly used in a bulk form by preserving all the novel characteristics of magnetic nanoparticles such as superparamagnetic behavior. By introducing magnetic properties of Fe₃O₄ nanoparticles into polymer fibers, novel magnetic properties combine with the advantages of composite fibers such as light-weight and ease-of-use. Using dry-jet-wet fiber spinning technology, we have successfully fabricated iron oxide/polyacrylonitrile (Fe₃O₄/PAN) composite fibers with 10 wt% nanoparticle in the polymer matrix. Composite fiber with a diameter as small as 15 μm can achieve tensile strength and tensile modulus values as high as 630 MPa and 16 GPa, respectively. Superparamagnetic properties of Fe₃O₄ nanoparticles were preserved in the composite fibers with saturation magnetization at 80 emu/g and coercivity of 165 G.     

A sonochemical method for synthesis of Fe3O4 nanoparticles and thermal stable PVA-based magnetic nanocomposite

Fe₃O₄ nanoparticles were synthesized via a simple surfactant-free sonochemical reaction. Room temperature synthesis without using inert atmosphere is the novelty of this work. The effect of different parameters on the morphology of the products was investigated. The magnetic properties of the samples were also investigated using an alternating gradient force magnetometer. Fe₃O₄ nanoparticles exhibit a ferromagnetic behavior with a saturation magnetization of 66 emu/g and a coercivity of 39 Oe at room temperature. For preparation magnetic nanocomposite, Fe₃O₄ nanoparticles were added to the polyvinyl alcohol (PVA). Nanoparticles can enhance the thermal stability and flame retardant property of the PVA matrix.     

磁性Fe3O4纳米粒子用作靶向药物载体的制备及分析

Fe3O4 magnetic nanoparticles were prepared by the aqueous co-precipitation of FeCl3-6H2O and FeCl2-4H2O with addition of ammonium hydroxide. The conditions for the preparation of Fe3O4 magnetic nanoparticles were optimized, and Fe3O4 magnetic nanoparticles obtained were characterized systematically by means of transmission electron microscope （TEM）, dynamic laser scattering analyzer （DLS） and X-ray diffraction （XRD）. The results revealed that the magnetic nanoparticles were cubic shaped and dispersive, with narrow size distribution and average diameter of 11.4 nm. It was found that the homogeneous variation of pH value in the solution via the control on the dropping rate of aqueous ammonia played a critical role in size distribution. The magnetic response of the product in the magnetic field was also analyzed and evaluated carefully. A 32.6 mT magnetic field which is produced by four ferromagnets was found to be sufficient to excite the dipole moments of 0.05 g Fe3O4 powder 2 cm far away from the ferromagnets. In conclusion, the Fe3O4 magnetic nanoparticles with excellent properties were competent for the magnetic carders of targeted-drug in future application.     

Magnetic-field-induced Fe3O4@CNTs/PES/SPSf composite membrane for efficient removal of methylene blue by adsorption and catalytic degradation

Novel composite membranes are successfully developed for adsorption and catalytic degradation of methylene blue (MB) by blending Fe₃O₄-coated CNTs (Fe₃O₄@CNTs) nanoparticles in polyethersulfone (PES) and sulfonated polysulfone (SPSf) matrix via nonsolvent-induced phase separation (NIPS) method assisted by magnetic field. Fe₃O₄@CNTs nanoparticles migrate to the separation layer under the induction of magnetic field, thus Fe₃O₄@CNTs/PES/SPSf composite membranes prepared under magnetic field exhibit a better dye removal ability compared with that without magnetic field. The MB removal ratio by Fe₃O₄@CNTs/PES/SPSf composite membrane containing 8 wt% Fe₃O₄@CNTs (M2−M) can reach up to 99% in 30 min under the conditions of 0.25 g composite membrane, 20 mg/L MB, 0.1 mol/L H₂O₂, pH = 3 and 80°C. Furthermore, the composite membranes show excellent recycling performance, as the MB removal capacity remains at 99% even after four cycles.     

Synthesis,characterization of Fe3O4@glycine doped polypyrrole magnetic nanocomposites and their potential performance to remove toxic Cr(VI)

Fe₃O₄ coated glycine doped polypyrrole magnetic nanocomposite (Fe₃O₄@gly-PPy NC) was prepared via coating of suspended Fe₃O₄ nanoparticles with gly-PPy. FE-SEM and HR-TEM images indicated that Fe₃O₄ nanoparticles were encapsulated by precipitating gly-PPy moieties. Chromium(VI) adsorption followed a Langmuir isotherm with maximum capacity of 238–303 mg/g for a temperature range of 25–45 °C at pH 2. The adsorption process was governed by the ionic interaction and the reduction of Cr(VI) to Cr(III) by the PPy moiety. Results showed that NCs are effective adsorbents for the removal of Cr(VI) from wastewater and can be separated by external magnetic field from the reactor.     

Magnetic properties and self-heat behaviors of core@shell structured MnFe2O4@Fe3O4 magnetic nanoparticles

In this work, a facile solvothermal synthesis of MnFe₂O₄ nanoparticles is followed by an easy and reproducible process to envelop the synthesized MnFe₂O₄ nanoparticles with iron oxide nanoparticles using ethanol and ethylene glycol as solvents. All prepared MnFe₂O₄ nanoparticles show a homogenous distribution of spherical particles with an average particle size between 12 and 16 nm. The encapsulation process of MnFe₂O₄ nanoparticles does not affect their homogenous distribution with a very thin layer of Fe₃O₄ on the shell structure. The magnetic properties showed a superparamagnetic character with enhanced magnetic properties of MnFe₂O₄@Fe₃O₄ compared to pure MnFe₂O₄, which has been verified by magnetization and electron spin resonance. The heating efficiency of the prepared samples was evaluated in terms of the specific loss power using the calorimetric method. The synthesized MnFe₂O₄ nanoparticles show a significantly high value of about 72 W/g, which got doubled in the core@shell structure and reached 140 W/g at 189 kHz and 10kA/m of the magnetic field.     

Significant magnetoelectric enhancement of composite films of CoZnxFe2-xO4 particles and poly (vinylidene fluoride-trifluoroethylene) for AC magnetic sensors

Polymer-based magnetoelectric (ME) nanocomposites exhibit a low ME effect and high bias field at room temperature, which severely limits their application in flexible wearable sensors. To overcome these obstacles, Zn-doped magnetic nanoparticles of CoZn_xFe_2-xO₄ (x = 0, 0.1, 0.2, and 0.3) were prepared by an auto-combustion method in this work. The obtained magnetostrictive curves imply that Zn element doping can improve greatly the piezomagnetic coefficient of magnetic nanoparticles, and among the tested materials, CoZn_0.1Fe_1.9O₄ has the largest piezomagnetic coefficient. Composite films of poly(vinylidene fluoride-trifluoroethylene) and CoZn_0.1Fe_1.9O₄ (P(VDF-TrFE)/CoZn_0.1Fe_1.9O₄) were prepared by spin coating. The maximum ME voltage coefficient of P(VDF-TrFE)/CoZn_0.1Fe_1.9O₄ composite film with a filler weight concentration of 10 wt% is 87.9 mV cm⁻¹ Oe⁻¹ with a bias field of 1050 Oe and a resonance frequency of 46 kHz, which is the highest value reported in the literature of 0–3 type polymer-based ME composite films at present. To evaluate the composite films for application in magnetic sensors, the ME output voltage was measured at a bias field of 1050 Oe with increasing AC magnetic field, demonstrating a good linear relationship with linearity of 0.999. These results indicate that the piezomagnetic coefficient of magnetic materials is an the important factor for the great enhancement of the ME voltage coefficient. This work provides a new approach for the synthesis of more effective polymer-based ME nanocomposites for potential applications in smart wearables.     

Synthesis and characterization of Sr2+ and Gd3+ doped magnetite nanoparticles for magnetic hyperthermia and drug delivery application

Commendable efforts have been gingered towards the fight against cancer. Nevertheless, it remains a major public health concern due to its predominant cause of death globally. Given this, we synthesized two different nanoparticles, Sr²⁺ and Gd³⁺ doped magnetite for magnetic hyperthermia and drug delivery application. Based on the characterization, the diffractogram shows that only one phase related to magnetite with a crystallite size of 10 nm was formed. TEM images revealed nanoparticles of spherical shapes of approximately 12 nm. There is no difference in magnetic saturation of the as-received synthesized samples (Fe₃O₄@Sr and Fe₃O₄@Gd), while the BET-specific surface area of Fe₃O₄@Gd is 8 m² g⁻¹ higher than Fe₃O₄@Sr. The heat generation in alternating magnetic field (the magnetic hyperthermia) of Fe₃O₄@Sr functionalized with citric acid and loaded with 5- fluorouracil (Fe₃O₄@Sr@CA@5-flu) is slower than Fe₃O₄@Gd@CA@5-flu. The specific absorption rate (SAR) of Fe₃O₄@Gd@CA@5-flu, 112.0 ± 10.4 W g⁻¹ was found to be higher than that of Fe₃O₄@Sr@CA@5-flu. The thermogram shows that 11% of the drug was successfully loaded on Fe₃O₄@Gd@CA@5-flu. The release of the antitumor drug by the synthesized nanoparticle drug carriers for ovarian cancer (SKOV-3 cells) therapy showed that more than 50% of the cancer cell’s viability was reduced after 72 h of incubation. The synthesized nanoparticles demonstrated a promising drug carrier for the treatment of SKOV-3 cells.     

A magnetically recyclable TS-1 for ammoximation of cyclohexanone

In this paper, Fe₃O₄ nanoparticles coated with titanium silicalite-1 (designated Fe₃O₄@TS-1) were successfully prepared and used as catalysts for ammoximation of cyclohexanone. Characterizations demonstrated that the magnetic catalyst was coated with a thin TS-1 layer of ~ 30 nm in thickness. The catalyst still displayed excellent catalytic activity after introducing Fe₃O₄ core. Recovery experiments revealed that Fe₃O₄@TS-1 catalyst could be easily recovered by adding an external magnetic field. Moreover, no appreciable catalytic deactivation was observed after four times of recycling. This work provided a promising way to overcome the recycle problem during the application of TS-1.     

Synthesis and analysis of structural,compositional, morphological,magnetic, electrical and surface charge properties of Zn-doped nickel ferrite nanoparticles

Zn-doped nickel ferrite nanoparticles (Zn_xNi_(1-x)Fe₂O₄) were synthesized using the co-precipitation technique. The structural and compositional studies of the Zn_xNi_(1-x)Fe₂O₄ nanoparticles revealed their face-centred cubic spinel structure and an appropriate amount of Zn doping in nickel ferrite nanoparticles, respectively. The morphological analysis had been carried out to obtain the particle size of the synthesized nanoparticles. The magnetic studies revealed the superparamagnetic nature of the Zn_xNi_(1-x)Fe₂O₄ nanoparticles, and the maximum magnetization of 30 emu/g for the Zn_0.2N_0.8Fe₂O₄ sample. The M ? H curves were fitted with the Langevin function to obtain the magnetic particle diameter of Zn_xNi_(1-x)Fe₂O₄ nanoparticles. The electrical conduction in Zn_xNi_(1-x)Fe₂O₄ nanoparticles was explained through the Verway hopping mechanism. The Zn_0.2N_0.8Fe₂O₄ nanoparticle exhibited a higher electrical conductivity of 42 μS/cm and surface charge of ?29/7 mV due to the enhanced hopping of Fe³⁺ ions in the octahedral sites. Owing to this nature, they were identified as the suitable candidates in the applications such as thermoelectrics, hyperthermia, magnetic coating and for the preparation of conducting ferrofluids.     

Magnetically aligning multilayer graphene to enhance thermal conductivity of silicone rubber composites

The increasing demand for packaging materials calls for new technologies to achieve excellent thermal conductivity of polymer composites with low content of thermal conductive filler. This article prepared a kind of magnetically functionalized multilayer graphene (Fe₃O₄@MG) via electrostatic interactions, which efficiently enhanced the thermal conductivity of silicone rubber (SR) composites by the alignment of Fe₃O₄@MG in an external magnetic field. The morphology and structure of the Fe₃O₄@MG together with the thermal conductivity of corresponding Fe₃O₄@MG/SR composites were systematically investigated by SEM, TEM, XRD, elemental mapping, and thermal conductivity tester. The obtained results showed that Fe₃O₄@MG was induced to form chain-like bundles in silicone rubber matrix under the applied magnetic field, which enhanced the MG–MG interaction, and formed effective thermal pathways in the alignment direction. Furthermore, as coating mass ratio of Fe₃O₄@MG increased, the thermal conductivity of randomly oriented Fe₃O₄@MG/silicone rubber composites (R-Fe₃O₄@MG/SR) decreased gradually, whereas the through-plane thermal conductivity of vertically aligned Fe₃O₄@MG/silicone rubber composites (V-Fe₃O₄@MG/SR) increased even filled with same contents of thermal conductive filler. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47951.     

Mg0.5Ni0.5Fe2O4 nanoparticles as heating agents for hyperthermia treatment

In the present work, Mg_0.5Ni_0.5Fe₂O₄ nanopowders were prepared by a sol-gel combustion method. The magnetic properties, heat generation ability in an AC magnetic field and cytotoxicity of the mixed ferrite nanopowders were investigated. The results showed that the powders have crystalline spinel structure with a particle size in the range of 20-90 nm. Maximum saturation magnetization (Ms) of 51 emu/g was obtained for the Mg_0.5Ni_0.5Fe₂O₄ nanoparticles calcined at 900°C. The results showed that, the coercivity (Hc) of the Mg_0.5Ni_0.5Fe₂O₄ initially increases up to 700°C and then decreases with increasing temperature, whereas the Ms of the samples continuously increases. The Mg_0.5Ni_0.5Fe₂O₄ sample exhibited a temperature increase up to 45°C during 10 minutes in the exposure of magnetic field of 200 Oe. By increasing the viscosity of ferrofluid, the heat generation ability of nanoparticles reduced up to 9% at magnetic field of 200 Oe. Cell compatibility of the ferrite powders was studied by MTT assay using MG63 cell line proliferation. MTT results showed that calcination temperature of the Mg_0.5Ni_0.5Fe₂O₄ nanoparticles significantly affects the cell compatibility.     

Cytotoxic effect of functionalized superparamagnetic samarium doped iron oxide nanoparticles for hyperthermia application

Magnetic Fluid Hyperthermia (MFH) is an emerging and safe technique for cancer treatment. Radiotherapy and Chemotherapy are widely adopted techniques for treating cancer but cause damage to the nearby healthy tissue. This paves the way for hyperthermia treatment for cancer. Since healthy cells are more heat-tolerant than malignant cells, magnetic nanoparticles with superparamagnetic properties were used in hyperthermia treatment. Surface modified magnetite (Fe₃O₄) iron oxide nanoparticles with enhanced stability, solubility, bio-compatibility and magnetic property were employed in hyperthermia treatment. In the present study, Superparamagnetic Samarium doped magnetite (Fe₃O₄:Sm) nanoparticles were functionalized with Oleylamine (OAm) and polyvinyl alcohol (PVA) by the sol-gel process. The obtained nanoparticles were characterized by X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Transmission Electron Microscopy (TEM), and UV–Visible diffuse reflectance spectroscopy (UV-DRS), Thermogravimetric analysis (TGA) and Vibrating Sample Magnetometer (VSM). From XRD data, the crystallite size of oleylamine coated samarium doped magnetite (OAm–Fe₃O₄:Sm) and PVA-coated samarium doped Fe₃O₄ (PVA- Fe₃O₄:Sm) were found to be 9.5 nm and 10.9 nm, respectively. TEM images of the functionalized nanoparticles were visualized as a spherical structure with reduced agglomeration. UV-DRS gives the bandgap value of OAm–Fe₃O₄:Sm and PVA- Fe₃O₄:Sm coated samarium doped magnetite to be 2.3 eV and 2 eV respectively. VSM measurement of OAm-Fe₃O₄:Sm and PVA- Fe₃O₄:Sm coated, showed superparamagnetic behaviour. The cytotoxicity study on the L929 cell line shows that both oleylamine and PVA-coated samarium doped magnetite were less toxic and biocompatible compared to the uncoated Fe₃O₄:Sm. The hyperthermia study reveals a rise in temperature within a few seconds with a high Specific Absorption Rate (SAR) value, confirming that the functionalized Samarium doped Fe₃O₄ was an effective nanomaterial for hyperthermia application.     

Synthesis and Characterization of Magnetically Retrievable Fe3O4/Polyvinylpyrrolidone/Polystyrene Nanocomposite Catalyst for Efficient Catalytic Oxidation Degradation of Dyes Pollutants

Recently, the application of metal oxides such as Fe₃O₄ nanoparticles have wide interest for environmental remediation and treatment of wastewater especially contaminated with azo dyes owing to its high degradation efficacy and low toxicity. The recovery of magnetic catalysts without losing their efficiency is an essential feature in the catalytic applications. The aim of this article is to investigate and synthesis of magnetically retrievable Fe₃O₄/polyvinylpyrrolidone/polystyrene (Fe₃O₄/PVP/PS) nanocomposite for the catalytic degradation of azo dye acid red 18 (AR18). Fe₃O₄/PVP/PS nanocomposite was prepared in two steps. Firstly, PVP/PS microsphere was synthesized by γ-irradiation polymerization of styrene in presence of PVP solution. Secondly, deposition of Fe₃O₄ nanoparticles on PVP/PS microsphere was achieved by the alkaline co-precipitation of Fe³⁺/Fe²⁺ ions. The chemical structural and morphological properties of PVP/PS microsphere and Fe₃O₄/PVP/PS nanocomposite were examined by XRD, TEM, DLS, FTIR, EDX and VSM techniques. TEM results showed homogeneous morphology, spherical shaped and well-dispersed Fe₃O₄ nanoparticles with average particle size of 26 nm around PVP/PS microspheres. The VSM measurements of Fe₃O₄/PVP/PS nanocomposite exhibit excellent magnetic response of saturation magnetization 26.38 emu/g which is suitable in magnetic separation. The effect of the synthesized Fe₃O₄/PVP/PS nanocomposite on the catalytic degradation of AR18 in presence of hydrogen peroxide (H₂O₂) as a heterogeneous Fenton-like catalyst was examined. The catalyst Fe₃O₄/PVP/PS/H₂O₂ played basic role in promoting the oxidation degradation efficiency of AR18 of initial concentration 50 mg/L to 94.4% in 45 min with excellent recyclability till the sixth cycles under the best conditions of pH 3, 2% v/v H₂O₂ and 0.3 g catalyst amount. Furthermore, the Fe₃O₄/PVP/PS/H₂O₂ hybrid catalyst system supports high capability for oxidation degradation of mixture of different dyes. The Fe₃O₄/PVP/PS nanocomposite catalyst had high magnetic and recyclability characters which are acceptable for the treatment of wastewater contaminated by various dyes pollutants.

     

Preparation and sedimentation behavior of conductive polymeric nanoparticles

A facile route to prepare Fe₃O₄/polypyrrole (PPY) core-shell magnetic nanoparticles was developed. Fe₃O₄ nanoparticles were first prepared by a chemical co-precipitation method, and then Fe₃O₄/PPY coreshell magnetic composite nanoparticles were prepared by in-situ polymerization of pyrrole in the presence of Fe₃O₄ nanoparticles. The obtained nanoparticles were characterized by scanning electronic microscopy (SEM), transmission electronic microscopy (TEM) and laser particle size analyzer. The images indicate that the size of Fe₃O₄ particles is about 10 nanometers, and the particles are completely covered by PPY. The Fe₃O₄/PPY core-shell magnetic composite nanoparticles are about 100 nanometers and there are several Fe₃O₄ particles in one composite nanoparticle. The yield of the composite nanoparticles was about 50%. The sedimentation behavior of Fe₃O₄/PPY core-shell magnetic nanoparticles in electrolyte and soluble polymer solutions was characterized. The experimental results indicate that the sedimentation of particles can be controlled by adjusting electrolyte concentration, solvable polymers and by applying a foreign field. This result is useful in preparing gradient materials and improving the stability of suspensions.     

Immobilization of Aspergillus niger xylanase A on Fe3O4-coated chitosan magnetic nanoparticles for xylooligosaccharide preparation

Aspergillus niger xylanase A (XylA) was immobilized onto Fe₃O₄-coated chitosan magnetic nanoparticles prepared by the layer-by-layer self-assembly approach. The Fe₃O₄-coated chitosan magnetic nanoparticles showed a high binding capacity of 162.2 mg ∙ g^− 1-particles and a recovery activity of 56.5% for XylA. The immobilized XylA showed improved thermostability and storage stability compared with free XylA. The immobilized XylA retained 87.5% activity after seven successive reactions by magnetic separation. Xylotriose and xylohexaose were the main products released from birchwood xylan and wheat bran insoluble xylan by immobilized XylA, respectively.     

Mechanical and magnetic response of magneto-rheological elastomers with different types of fillers and their hybrids

The use of secondary reinforcing fillers such as graphene or multi-wall carbon nanotube (CNT) for improving mechanical properties is an effective strategy to obtain high performance magneto-rheological elastomers (MREs). Therefore, MREs were prepared via solution mixing of room-temperature-vulcanized silicone rubber (RTV-SR) and iron oxide (Fe₃O₄), and hybridized with iron wire, Few-layer graphene (FLG), and CNT as secondary nanofillers. The isotropic mechanical properties were studied through compressive tests, and their compressive moduli and reinforcing factors were determined. From these studies, it was found that CNT-based hybrid MREs show the highest compressive mechanical properties. For example, at 80 per hundred parts of rubber (phr), the compressive modulus was 3.5 MPa (RTV-SR/Fe₃O₄), 4.1 MPa (RTV-SR/Fe₃O₄-FLG), 5.5 MPa (RTV-SR/Fe₃O₄-CNT), and 3.7 MPa (RTV-SR/Fe₃O₄-iron wires). A nanofiller with higher aspect ratio (CNT), has a strong effect on the isotropic mechanical properties, whereas a lower aspect ratio nanofiller (FLG) has a greater effect on magnetic sensitivity. Although iron wires with lower specific surface areas can only improve the mechanical properties slightly, they can improve the magnetic sensitivity of MREs because of its stronger magnetic behavior.     

Facile fabrication of nanocomposite microspheres with polymer cores and magnetic shells by Pickering suspension polymerization

Pickering suspension polymerization was used to prepare magnetic polymer microspheres that have polymer cores enveloped by shells of magnetic nanoparticles. Styrene was emulsified in an aqueous dispersion of Fe₃O₄ nanoparticles using a high shear. The resultant Pickering oil-in-water (o/w) emulsion stabilized solely by magnetic nanoparticles was easily polymerized at 70 °C without stirring. Fe₃O₄ nanoparticles act as effective stabilizers during polymerization and as building blocks for creating the organic–inorganic hybrid nanocomposite after polymerization. The fabricated magnetic nanocomposites were characterized by FTIR, XRD, TGA, DSC, GPC, XPS and SEM. The structures of the polymer core and the nanoparticle shell were analyzed. We investigated the effects on the products of the weight of Fe₃O₄ nanoparticles used to stabilize the original Pickering emulsions. Pickering suspension polymerization provides a new route for the synthesis of a variety of hybrid nanocomposite microspheres with supracolloidal structures.     

Efficient visible light magnetic modified iron oxide photocatalysts

Magnetite iron oxide (Fe₃O₄) nanoparticles were synthesized via simple co-precipitation method using ferrous and ferric ions salts. Fe₃O₄ nanoparticles were modified by silica and titania. Pure and modified nanoparticles were employed for dye degradation under visible light. X-ray diffraction analysis indicated inverse spinel structure of Fe₃O₄ nanoparticles. The particle size of magnetite nanoparticles is decreased due to coating of silica and titania. Scanning and transmission electron microscopy indicated the spherical morphology for all samples. The synthesized Fe₃O₄ nanoparticles were ferromagnetic in nature with highest saturation magnetization value of 1.1034 emu as compared to silica and titania coated samples. Fourier transform infra-red spectra confirmed the incorporation of magnetite nanoparticles with silica and titania. Titania modified magnetite sample showed the highest photocatalytic activity as compared to silica modified magnetite nanoparticles and bare iron oxide under visible light irradiations.     

Functional acrylic acid as stabilizer for synthesis of smart hydrogel particles containing a magnetic Fe3O4 core

This paper reports a novel method to synthesize magnetic, stimuli-sensitive latex nanoparticles made with magnetite/poly(N-isopropylacrylamide-co-acrylic acid) (Fe₃O₄/P(NIPAAm-co-AAc)). To form a stabilized suspended core, iron oxide (Fe₃O₄) was functionalized with AAc such that further polymerization with NIPAAm and AAc monomers could occur. The P(NIPAAm-co-AAc) shell layer exhibited thermosensitive properties. The inclusion of Fe₃O₄ into the latex nanoparticles was confirmed using transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction spectroscopy, thermogravimetric analyzer (TGA), and superconducting quantum interference device magnetometer. The NIP–(AAc2.6–Fe) latex nanoparticles contained 2.25% Fe₃O₄ (by weight), as determined by TGA analysis. The particle diameters measured approximately 160–240 nm with a lower critical solution temperature of 35 °C. These novel magnetic stimuli-responsive latex nanoparticles have potential applications in numerous fields, such as catalyst supports, protein immobilization, cancer therapy, target drug delivery systems, and other biomedical applications.