The effect of improved rations and different doses of Glutamevitum on the vitamin status and work capacity of children who started school at the age of 6 years

The influence of qualitatively different nutrition and additional vitaminization with varying doses of "Glutamevitum" on excretion with urine of vitamins B1, B2 PP and C, as well as the presence of microclinical symptoms of vitamin deficiency and psychophysiological parameters were studied in 120 children (6 groups, 20 subjects in each) who went to school at six years of age. The children received corrected nutrition and vitamins during 6 months of the winter-spring period. It was established that the nutrition corrected by selection of food products and additional vitaminization with optimal doses of vitamins (1/2 tablet of "Glutamevitum" added by vitamins C, P and A in a dose of 10, 30, 0.25 mg, respectively) significantly lowered fatigue as a result of psychoemotional and mental stress in children of 6 years of age studying at school, vitamin excretion with urine increased, microclinical symptoms of vitamin deficiency were appreciably lowered, the working capacity and attention as well as nervous-reflectory activity were significantly improved in the critical period of early studying.     

The vitamin C, B12 and folate allowances of pregnant women in Moscow]

A dietary supply of vitamins was studied in 212 pregnant women for 11 months. Mean blood levels of vitamins were found subnormal, the percentage of the women with vitamin deficiency increased. Especially inadequate was supply of folate followed by vitamin C. Intake of 1 dragee a day of polyvitamins "Gendevitum" improved the vitamin status of the examinees with the best results obtained in the first trimester. Folate and B12 levels decreased with advance of pregnancy irrespective of polyvitamins administration. Vitamin C supply was better in summer and autumn, folate levels were higher in winter and spring. It is suggested that vitamins C, B12 and folate deficiency observed in pregnancy should be corrected.     

Effect of dietary correction and administration of multivitamin preparations on providing rural technical school students with vitamin C and B 1

Actual nutrition and providing with vitamins C and B1 were studied in students of rural trade school (youths aged 16-17 years) in the town of Volsk, the Saratov region. The actual nutrition was corrected by inclusion of curds and other milk and vegetable products into the ration. The content of ascorbic acid in the usual and corrected rations, estimated analytically, during spring comprised 17 and 29%, and vitamin B1--49 and 75% of the recommended standard. The insufficient providing of the students with vitamins C and B1 in spring was confirmed by their low level of excretion with urine, and by lowered vitamin C concentration and activity of vitamin B1-dependent enzyme transketolase in the blood of the investigated students. The ration correction improved to a certain extent the values of providing with vitamins C and B1 but could not eliminate vitamin deficiency. Administration of "Undevitum" in a dose of 1 dragee/day during 4 months eliminated the vitamin deficiency in the ration and provided optimum vitamin levels for the students.     

Experimental-hygienic basis for the preventive nutrition of workers exposed to intense industrial noise

Provision with vitamins C, P, B6, PP, changes in the blood serum creatine kinase activity, some parameters of carbohydrate metabolism and integral values were studied in rats exposed to the 30-day action of stable "white" noise with the intensity of 100 dB A, in the presence of both usual physiologic and specially developed, pathogenetically validated nutrition. Simultaneously, the above biochemical parameters, acoustic sensitivity and subjective data were comparatively investigated in two groups of workers of "noisy" occupations. It was shown that the proposed prophylactic ration produced a favourable effect on the studied parameters of the body exposed to intensive industrial noise.     

Effects of biologically active food additives with different contents of vitamins on the vitamin status in humans

The comparative study of influence of two biologically active food additives with the different contents of vitamins is carried out: a drink "Zolotoi Shar", the dose of vitamins in which makes 50-90% from recommended daily consumption, and "Vitabalance 2000", the contents of vitamins in which at 2-17 of time exceeds need of organism. The use of both additives within 3 weeks resulted in increase of levels of vitamins C, A, E, B2, B6 and carotenoids in blood serum. However if in case of consumption of a drink an authentic level was reached only for vitamin C and beta-carotene, in a case "Vitabalance 2000" for all investigated vitamins except vitamin A. Thus, if the consumption of a drink has lowered frequency of deficiency of 3-4 vitamins, but has not allowed to liquidate it completely, in case of "Vitabalance 2000" consumption the simultaneous deficiency 3-4 vitamins. The received data allow to believe the biologically active food additives containing vitamins in amounts exceeding recommended consumption, are convenient for fast liquidation of hypovitaminoses, and the preparations containing vitamins in doses making 30-50% from need of organism, are acceptable for daily filling of insufficient consumption of vitamins with a usual diet for a long time.     

Sources of energy values and contribution of various products to maintenance of chemical contents of the diet of an unorganized population of Moscow

With use of a method of daily reproduction at representative sample of an unorganized population of inhabitants of Moscow the sources of energy value and contribution of various products to supply organism by the basic food substances (protein, fats, carbohydrates and cholesterol) are investigated. Is established that the nutrition structure is obviously debalanced. More quarters of daily diet energy is provided for consumption of animal fats and simple sugars. Is shown that the main part of fat (2/3) enters in organism as the "latent" fats of animal products, the fats "in the pure form" half consist from butters. The main source of the saturated fats and cholesterol for men are meat, and for women--the dairy products. 12% researched refuse purified sugars.     

The vitamin allowance of the pupils in a rural vocational and technical school and their prophylactic vitaminization]

The actual nutrition and providing with vitamins C and B1 was studied in boys aged 16-17 years, students of a rural trade school (Volsk of Saratov Province). Although the caloric value of their ration was high enough the content of animal proteins was only 42-48 g/day. The content of ascorbic acid in the ration comprised 48%, in the spring of 1987 it was 17%, and of 1988-29% of the recommended standard, vitamin B1 levels did not show seasonal differences. Vitamin C and B1 deficiencies in the spring were proved by their low excretion levels in urine, and by a low concentration of vitamin C and decreased activity of B1-dependent enzyme transketolase in the blood. Intake of "Undevitum" (1 dragee/day) during 4 months was conductive to the improvement of the student providing with vitamins.     

Biologically active food supplements in comprehensive therapy of patients with ischemic heart disease and hypertension and the background of overweight

The influence of anti-atherosclerotic diet with including some biologically active additives, with contain vitamins C, E, beta-carotene, Zn, Cr, Se was studied in 80 patients with ischemic heart disease, hypertension disease. The usage of biologically active additives during 4 weeks has promoted positive changes of clinical symptoms of diseases against a background of lowering of serum cholesterol, triglycerides and increasing of IgA, IgG, vitamins A, E, C.     

关于营养素补充剂管理相关问题的刍议

营养素补充剂是指以补充维生素、矿物质而不是以提供能量为目的的产品。其作用是补充膳食供给的不足,预防营养缺乏和降低发生慢性退行性疾病的危险性。就营养素补充剂的管理中的原料和辅料,维生素、矿物质的标示值、企业标准中的范围值,及人群推荐摄入量范围进行了讨论,并提出了相关的政策建议。     

A 100-Year Review: From ascorbic acid to zinc—Mineral and vitamin nutrition of dairy cows

Mineral and vitamin nutrition of dairy cows was studied before the first volume of the Journal of Dairy Science was published and is still actively researched today. The initial studies on mineral nutrition of dairy cows were simple balance experiments (although the methods available at the time for measuring minerals were anything but simple). Output of Ca and P in feces, urine, and milk was subtracted from intake of Ca and P, and if values were negative it was often assumed that cows were lacking in the particular mineral. As analytical methods improved, more minerals were found to be required by dairy cows, and blood and tissue concentrations became primary response variables. Those measures often were poorly related to cow health, leading to the use of disease prevalence and immune function as a measure of mineral adequacy. As data were generated, mineral requirements became more accurate and included more sources of variation. In addition to milk yield and body weight inputs, bioavailability coefficients of minerals from different sources are used to formulate diets that can meet the needs of the cow without excessive excretion of minerals in manure, which negatively affects the environment. Milk, or more accurately the lack of milk in human diets, was central to the discovery of vitamins, but research into vitamin nutrition of cows developed slowly. For many decades bioassays were the only available method for measuring vitamin concentrations, which greatly limited research. The history of vitamin nutrition mirrors that of mineral nutrition. Among the first experiments conducted on vitamin nutrition of cows were those examining the factors affecting vitamin concentrations of milk. This was followed by determining the amount of vitamins needed to prevent deficiency diseases, which evolved into research to determine the amount of vitamins required to promote overall good health. The majority of research was conducted on vitamins A, D, and E because these vitamins have a dietary requirement, and clinical and marginal deficiencies became common as diets for cows changed from pasture and full exposure to the sun to stored forage and limited sun exposure. As researchers learned new functions of fat-soluble vitamins, requirements generally increased over time. Diets generally contain substantial amounts of B vitamins, and rumen bacteria can synthesize large quantities of many B vitamins; hence, research on water-soluble vitamins lagged behind. We now know that supplementation of specific water-soluble vitamins can enhance cow health and increase milk production in certain situations. Additional research is needed to define specific requirements for many water-soluble vitamins. Both mineral and vitamin research is hampered by the lack of sensitive biomarkers of status, but advanced molecular techniques may provide measures that respond to altered supply of minerals and vitamins and that are related to health or productive responses of the cow. The overall importance of proper mineral and vitamin nutrition is known, but as we discover new and more diverse functions, better supplementation strategies should lead to even better cow health and higher production.     

Effect of the type of nutrition and aflatoxin B1 on the structure of chromosomes

Deficiency of the essential nutrients lysine, methionine, threonine and vitamins A, E, C significantly increases the mutagenic environment of somatic cells in growing Wag rats. Aflatoxin B1 produces a pronounced mutagenic effect on the cellular genetic apparatus; this effect is substantially modified due to the nutrition character: it is either intensified or inhibited. The results obtained suggest that the nutritional factors can de used for prevention and elimination of aflatoxin B1-induced mutations.     

Estimation of nutrition of elderly and senile patients with surgical diseases at home

Analysis of estimation of nutrition 500 of elderly and senile patients with surgical disease at home. The diets of patients are characterised by foods rich of animal protein and carbohydrate. But a dificienny of meat, fish, dairy products frent, berries is marhed. The diets thas dificiency in rations of patients are characterized by irrational set basic food products, cannot provide daily needs for nutrients: animal protein, vitamins C, A, vitamins B group, beta-carotene and mineral element--Ca, Mg, P, Zn, Se.Entering of nutrional substance, such as vitamins, and mineral elements with a food is reduced in dietary restrictions, deficiency means, residence in country-side.     

Effectiveness of use in preventive nutrition the food ptoducts with contents of pectin and vitamins

Daily inclusion in the diet of Pskov GRES workers the drinks or kissels containing 2 g pectin per daily serving (cup) during 6 months was accompanied by a statistically significant decline of their supply with vitamins C, B2, A and beta-carotene. This is reflected both in reducing the average vitamin concentration in blood serum and in the increase of the quota of people with deficiency of several vitamins. Additional inclusion of 13 vitamins in these drinks and kissels, in a dose about 80% of the RDA, has prevented the deterioration of vitamin status.     

Effects of biologically active supplements on the antioxidant and vitamin status of patients with hypertension and ischemic heart disease

Biologically active additives in integrated therapy of patients with cardiovascular diseases against a background body overweight. The influence of antiaterosclerotic diet with including some biologically active additives, which contain vitamins C, E, B2, B6, beta-carotene, Zn, Mg, Na, K, Ca, I was studied in 91 patients with ischemic heart disease, hypertension disease. The usage of biologically active additives during 4 weeks has promoted positive changes of clinical symptoms of diseases against a background of lowering of serum cholesterol, triglycerides and increasing of vitamins A, E, C, B2, B6.     

A comparison of the physico‐chemical properties of low‐cholesterol ghee with standard ghee from cow and buffalo creams

Low‐cholesterol ghee with 90% less cholesterol was prepared using β‐cyclodextrin. The physico‐chemical properties such as Reichert‐Meissl (RM) value, Polenske value, Butyro‐refractometer (BR) reading at 40°C, Iodine value and free fatty acids (FFA) as oleic acid in cow standard ghee and the corresponding low‐cholesterol ghee remained almost unaltered. A similar trend was also observed in buffalo ghee. Fat soluble vitamins (β‐carotene, A and E) in both cow and buffalo low‐cholesterol ghee were very similar to that of respective standard ghee samples. However, 65 to 70% loss of vitamin D was observed in low‐cholesterol ghee.     

Vitamin status of diamond cutters

Workers engaged in industrial treatment of diamonds manifested deficient supply of ascorbic acid, thiamine, riboflavin, pyridoxine and niacin in spring and autumn. This was ascertained on the basis of studying actual nutrition and specific indicators of the content of vitamins or their catabolites in the urine and blood and determination of metabolic functions of some vitamin-dependent enzymes.     

不同饲料喂养鸡蛋中胆固醇的含量测定

对A,B,C,D四组不同饲料喂养新鲜鸡蛋的胆固醇含量进行测定,比较鸡蛋的平均重量、蛋清相对重量、蛋黄相对重量、蛋壳相对重量、蛋壳厚度.筛选出胆固醇含量较低的营养保健型鸡蛋.结果表明:A、B组的胆固醇含量偏高.C和D组的胆固醇含量较低,所有其他检测指标基本上没有差异.综合营养和经济因素,D组的鸡蛋更适宜于加工生产.     

Provision of workers and employees of Kuzbass industrial enterprises with vitamins C, E, A and beta-carotene

The content of vitamins C, E, A and beta-carotene was studied in the blood serum of 404 workers and employees of the Kuzbass industrial enterprises. Insufficient providing of the body with ascorbic acid, tocopherol and beta-carotene has been revealed. The number of workers and employees with vitamin C deficiency comprises at an average 95%, with vitamin E deficiency--9%, and with beta-carotene deficiency--34%. Industrial enterprises characterized by hard physical labor and occupational health hazard have been found to be most unfavourable with respect to providing with vitamins. The results of the investigations conducted have evidenced the necessity of correcting the vitamin nutrition of the subjects studied.     

Vitamin allowance of cosmonauts during preflight training and after completing short space flights

Supply of the main and doubling crews of cosmonauts with vitamins C, A, D, E, B1, B2, B6, PP, and B12, folic acid and carotinoids was studied during training and after the completion of short-term space flights (from 4 to 13 days). As the result of the investigation conducted during the intensive training, 1 month before the space flight some cases of certain vitamins deficiency were revealed. Administration of additional vitamins during 2 weeks before the flight led to a rise in the cosmonauts' supply with vitamins. The findings obtained after the short-term space flights evidence an intensive metabolization of vitamins and increased vitamin requirements during this period.     

Preservation of vitamins during preparation of dry specialized dairy products

Preservation of vitamins A, E, C, B6, B1, B2, B5, Bc was studied during preparation of dried special-purpose milk mixtures ("Solnyshko", "Inpitan", enpits, low-lactose mixtures) and after storage ("Inpitan", and low-lactose mixtures) during 1 year at 4 and 18 degrees C. It has been established that vitamins A, E and C are most subjected to deterioration during production of dried special-purpose mixtures, their losses comprise 17-47, 18-43, 13-41%, respectively. B2 and B5 were most resistant in the process of the mixture production. No significant losses of vitamins were recorded during storage of "Inpitan" and low-lactose mixtures.