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1.
PURPOSE: To determine risk factors for secondary hemorrhage and poor visual outcome in children with traumatic hyphemas. METHODS: We reviewed 99 eyes of 97 children younger than 18 years who had been hospitalized for hyphema within 48 hours of blunt eye trauma. Inpatient records were examined for race, age, sickle cell trait status, size of hyphema and intraocular pressure at admission, secondary hemorrhage (rebleed of hyphema), and medications while hospitalized. Fifty-five eyes of 53 children had at least 1 month of follow-up or attained best-corrected visual acuity of 20/50 or better at their last outpatient visit. RESULTS: Among 99 eyes of 97 children with traumatic hyphema, secondary hemorrhage occurred in nine eyes (9%). Among 72 eyes of 70 African-American children, secondary hemorrhage occurred in nine eyes (14%), whereas in 27 eyes of 27 white children, there were no secondary hemorrhages. However, when the 14 eyes of 13 sickle cell trait-positive children were excluded from the African-American group, the 57 eyes of sickle cell trait-negative African-American and white children did not have any secondary hemorrhages. The sickle cell trait-positive group had secondary hemorrhages in nine of 14 eyes (64%), significantly (P < .005) different from the 0% rate in the 57 eyes of African-American sickle cell trait-negative and white children. The sickle cell trait-positive group also had higher intraocular pressure and permanent visual impairment. CONCLUSION: Sickle cell trait is a significant risk factor for secondary hemorrhage, increased intraocular pressure, and permanent visual impairment in children who have traumatic hyphemas following blunt trauma. 相似文献
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Besides the fast tetrodotoxin-sensitive Na+ current, small dorsal root ganglion neurones of rats also possess a slower tetrodotoxin-resistant Na+ current. The blocking effect of commonly used local anaesthetics upon the tetrodotoxin-resistant Na+ current was investigated in the present paper. Dorsal root ganglia were dissected from adult rats and cells were enzymatically isolated. The whole-cell patch clamp technique was then used to measure inward Na+ currents of small dorsal root ganglion neurones. Externally applied local anaesthetics reversibly blocked the tetrodotoxin-resistant Na+ current in a dose-dependent manner. Half-maximal blocking concentrations for tonic block were: lignocaine, 326 microM; prilocaine, 253 microM; mepivacaine, 166 microM; etidocaine, 196 microM bupivacaine, 57 microM procaine, 518 microM benzocaine, 489 microM; tetracaine, 21 microM; and dibucaine, 23 microM. Blocking of the current by lignocaine was independent of temperature. The quaternary lignocaine derivative OX-314 did not have any effect upon the tetrodotoxin-resistant Na+ current when applied externally. High concentrations of tetrodotoxin also blocked the tetrodotoxin-resistant Na+ current with a half-maximal blocking concentration of 115 microM. The block by high tetrodotoxin concentrations did not compete with the lignocaine block, suggesting that there were two independent blocking mechanisms for the two substances. The tetrodotoxin-resistant Na+ currents also showed a marked sensitivity to phasic (use-dependent) block by local anaesthetics. 相似文献
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How do clinical supervisors respond to supervisees' reports of sexualized or sexually harassing behaviors by patients? A survey of experienced supervisors was conducted to answer this question and to determine the incidence of such reports. A substantial number of participants reported receiving at least 1 report of patient sexual harassment of a supervisee. Reports ranged from persistent inappropriate sexual comments to physical sexual assaults. Supervisors' responses ranged from supervisory discussions to active interventions. Clinical supervisors must acknowledge the potential for supervisees to be sexually harassed by patients and incorporate strategies to deal with harassment in their training programs. (PsycINFO Database Record (c) 2011 APA, all rights reserved) 相似文献
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J Warszawski A Messiah J Lellouch L Meyer JC Deville 《Canadian Metallurgical Quarterly》1997,16(4):397-423
Two-phase stratification sampling with unequal selection probabilities is a relatively cost-efficient strategy to address problems on a nationwide basis and to perform comparative analyses of specific subgroups. This was the case with the ACSF survey. Specific procedures to estimate the variances of unbiased estimators in complex sampling designs are not included in standard statistical packages and no specialized software is available for two-phase sampling. A detailed synthesis of general basic rules for inference about a target population from a probability sample is first presented. We follow with a standard procedure to estimate means and percentages with their confidence intervals according to the design. Finally, numerical results are discussed. 相似文献
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A nationwide survey of 750 female psychologists practicing psychotherapy was conducted to determine the incidence of sexual harassment and potentially sexualized patient behaviors in clinical practice. A usable return rate of 48.7% was obtained (N?=?354). A total of 53.7% of the respondents reported at least 1 incident of sexual harassment. Events ranged from inappropriate verbal remarks to sexual assaults. Respondents reported an even higher incidence of sexually suggestive patient behaviors in clinical practice, although most of these were not experienced as sexual harassment. Implications for training and practice are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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OBJECTIVE: To determine obstetrician-gynecologists' (ob-gyns') awareness of and experience with sexual abuse of patients and former patients and their opinions about appropriate consequences. DESIGN: Mailed survey. SETTING: Canada. PARTICIPANTS: All 792 members of the Society of Obstetricians and Gynaecologists of Canada (SOGC); 618 (78%) responded. Approximately half of all ob-gyns in Canada belong to the SOGC. MAIN OUTCOME MEASURES: Knowledge of sexual involvement by an ob-gyn colleague with a patient or former patient (as defined by the respondents and by the College of Physicians and Surgeons of Ontario [CPSO]), self-report of such involvement, attitudes toward physician sexual abuse, desirable length of time a physician should wait before seeing a former patient in a situation that could lead to a sexual encounter, suggested consequences of sexual abuse. RESULTS: Overall, 10% of the respondents indicated that they knew about another ob-gyn who at some time had been sexually involved with a patient. In all, 3% of the male respondents and 1% of the female respondents reported sexual involvement with a patient; the corresponding proportions of those who reported having been accused of sexual abuse by a patient were 4% and 2%. Significantly more of the female ob-gyns than of their male counterparts (37% v. 19%) reported awareness of a colleague's sexual involvement with a patient that would meet the CPSO's definition of sexual impropriety, transgression or violation. Most of the respondents felt that the consequence of proven sexual impropriety should be reprimand and fine (chosen by 33%) or rehabilitation without loss of licence (28%). Most of the physicians supported loss of licence for proven sexual transgression (57%) or proven sexual violation (74%), but fewer felt that loss of licence should be permanent for these types of abuse (4% and 24% respectively). The female ob-gyns supported stronger sanctions against sexual transgression and sexual violation than the male ob-gyns. A wide range of opinion was seen regarding the propriety of sexual relationships with former patients. CONCLUSIONS: Ob-gyns have varied opinions about how sexual abuse of patients should be defined and how it should be sanctioned. There is a discrepancy between proposed public policy and the beliefs of physicians to whom the policy is to be applied. 相似文献
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The detection and measurement of somatic cell mutation in vivo is an important subject of research for the assessment of human cancer risk induced by various environmental genotoxic factors. The possible mechanisms which influence the persistence of mutant cells of the hematoimmune system in the peripheral blood are presented. The erythroid system is a system which accumulates mutational lesions and so stably generates red blood cells with various phenotypic changes. 相似文献
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Five patients underwent operative repair of an aneurysm of the sinus of Valsalva. Four of the aneurysms were considered as congenital and one as mycotic. There were four males and one female. One patient with VSD and characteristics of Marfan's syndrome die on the first postoperative day of a recurrence of fistulae. The follow-up time is over one year for all but one of the surviving patients. There are no late deaths, and all patients are doing well. Aneurysms and fistulae of the sinus of Valsalva, which are perhaps not as rare as was previously thought, present a challenging surgical problem. Ruptured aneurysms and fistulae, even if asymptomatic, should be treated operatively, preferably by a transaortic approach. 相似文献
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According to a 1991 study of sexual behavior based on a random sample of heterosexual undergraduates at a Midwestern university, 80% of the males and 73% of the females had experienced vaginal or anal intercourse. The average age at first vaginal intercourse was 17.2 years for both sexes. Seventeen percent of the sexually experienced males and 18% of the sexually experienced females had engaged in heterosexual anal intercourse; among these respondents, the average age at first anal intercourse was 20.3 for males and 19.1 for females. Although less than four years, on average, had elapsed since the respondents had first had vaginal intercourse, males reported an average of 8.0 lifetime vaginal-sex partners and females reported an average of 6.1. Overall, the findings from this random sample of students are similar to those from a 1988 convenience sample of the same college population. 相似文献
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OBJECTIVE: To explore the prevalence of, characteristics of, and factors associated with forgetting of childhood sexual abuse memories in a large non-clinical sample (N = 1712). METHOD: Using an anonymous survey, we asked respondents about (a) the nature and severity of their childhood abuse; (b) the continuity of their abuse memories; and (c) their experiences with others suggesting to them that they might have been abused. RESULTS: A substantial minority of victims in our sample reported having temporarily forgotten their childhood sexual abuse. Forgetting was largely unassociated with victim or abuse characteristics. Compared to individuals who always remembered their abuse, however, individuals who temporarily forgot were more likely to report that someone had suggested to them that they might have experienced abuse. Those who received such suggestions were particularly likely to suspect that they may have experienced childhood sexual abuse that they do not yet remember. CONCLUSION: Forgetting may be less common than implied by earlier estimates from clinical samples, yet it is not uncommon. Also, a sizable minority of the population is wondering whether they have experienced unremembered abuse, and these suspicions are linked to having encountered suggestions from others. We discuss the implications of these findings for understanding the phenomenon sometimes labeled repression. 相似文献
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OBJECTIVE: To investigate the current trend of use and abuse of antianxiety drugs in Beijing residents in 4 urban and 2 rural areas. METHODS: A cluster sampling household survey of 6567 subjects out of 3000 families was made by 6 local grass roots mental health centers collaboratively. Screened with designed questionnaire, the positive addicted subjects were examined with present state examination (PSE), eysenck personality questionnaire (EPQ) and social disability screening schedule (SDSS) to detect their psychosocial status. RESULTS: Benzodiazepine (BZD) has been widely prescribed and the rate of usage for 1 year is 61.82/1000, whereas the rate of dependence is 16.29/1000, constituting 1/4 of long-term users. This study also indicates that Valium is a most preferred drug among all available BZD used by the majority of addicted subjects. CONCLUSIONS: It is concluded that the reported dependence is not epidemic but iatrogenic in nature attributable to persistent misuse of BZD. It is stressed that guideline of rational clinical application of BZD should be laid down so as to markedly reduce further possible misuse and abuse of the drugs of this kind. 相似文献
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Rule Nicholas O.; Ambady Nalini; Adams Reginald B. Jr.; Macrae C. Neil 《Canadian Metallurgical Quarterly》2008,95(5):1019
For clear and unambiguous social categories, person perception occurs quite accurately from minimal cues. This article addresses the perception of an ambiguous social category (male sexual orientation) from minimal cues. Across 5 studies, the authors examined individuals' actual and self-assessed accuracy when judging male sexual orientation from faces and facial features. Although participants were able to make accurate judgments from multiple facial features (i.e., hair, the eyes, and the mouth area), their perceived accuracy was calibrated with their actual accuracy only when making judgments based on hairstyle, a controllable feature. These findings provide evidence that suggests different processes for extracting social category information during perception: explicit judgments based on obvious cues (hairstyle) and intuitive judgments based on nonobvious cues (information from the eyes and mouth area). Differences in the accuracy of judgments based on targets' controllability and perceivers' awareness of cues provides insight into the processes underlying intuitive predictions and intuitive judgments. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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ML Heiman S Leiblum S Cohen Esquilin L Melendez Pallitto 《Canadian Metallurgical Quarterly》1998,22(4):289-304
OBJECTIVE: This study sought to collect data on what adults believe constitutes normal childhood sexual behaviors, and how variables, such as role, gender, and life experience might contribute to the formation of one's beliefs. METHODS: A survey describing 20 different scenarios of children under the age of 13 interacting with themselves or other children in a sexual manner was administered to four groups of adults: sexual abuse experts; therapists involved in a sexual abuse training program; medical students attending a human sexuality program; and group facilitators of the human sexuality program. RESULTS: Behaviors that involved oral, vaginal, or anal penetration were judged by a majority of adults to be abnormal sexual behaviors in children under 13 years of age. Professionals working with sexually abused children rated certain sexual behaviors as more abnormal than adults participating in a human sexuality course. Both sexual abuse trainees and facilitators of the human sexuality course showed more directional biases than other groups, with trainees always rating behaviors in the direction of abnormal and facilitators always rating behaviors in the direction of normal. Females also judged many of the sexual behaviors to be more abnormal than males. CONCLUSIONS: Role and gender significantly influence what adults believe constitutes normal and abnormal childhood sexual behavior. 相似文献
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Surveyed therapists regarding their practices in assessing clients' sexual abuse history. Of the 105 respondents, 51% reported that they routinely ask all clients or most clients about sexual abuse at some time during the course of therapy; 19% reported that they had asked only a few clients or that they never ask clients directly about sexual abuse. Therapists who were younger, who had been in practice for a shorter period of time, and whose current caseload included a high percentage of sexually abused women were most likely to have asked all or most of their clients about having been sexually abused. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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Nelson Geoffrey; Prilleltensky Isaac; Laurendeau Marie-Claire; Powell Barbara 《Canadian Metallurgical Quarterly》1996,37(3):161
The purpose of this research was to obtain a profile of the state of prevention in mental health in Canada. In all the provinces and territories, we obtained information from the departments of children's mental health, adult mental health, and health promotion regarding administrative supports, personnel, policies, budgets, inter-ministerial collaboration, training, and programs allocated for prevention. The findings indicate that the rhetoric of prevention is present in many government policy documents and there are many interesting prevention projects that have been implemented. However, there has not been a reallocation of funding in the health field from treatment and rehabilitation services to prevention programs, and funding for prevention remains at a very low level. Recommendations to improve the state of prevention are made. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
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This article reviews the link between childhood sexual and/or physical abuse and adult self-harm, suicidal ideation, and suicidal attempt from 1988 to 1998 in the clinical literature. Despite the methodological and definitional concerns, empirical studies have generally demonstrated more reports of self-harm, suicidal ideation, and suicidal behaviour in clinical and community populations of adults who report sexual and/or physical abuse in childhood than in comparison groups who do not report abuse. Implications for practice include the identification of populations at risk for self-harm or suicide and routine inquiry of abuse histories on admission. Further research into universal definitions of the key terms, standardized measurements of the variables, and longitudinal studies is required. 相似文献
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A study on lead pollution was carried out on a sample of ca. 300 city children. This paper presents the errors producing bias in the sample. It is emphasized that, in Switzerland, the difference between the Swiss and the migrant population (the latter being mainly Italian and Spanish) must be taken into account. 相似文献
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Flagellin gene central regions from 111 isolates of Pseudomonas fluorescens SBW25 obtained from soil during a field release experiment were analysed using a combined PCR/RFLP technique to look for variation. In addition, a 858 bp flagellin gene sequence from the original strain and the last isolate obtained from the release site were compared. There was no variation in flagellin gene sequences indicating that the gene was stable over the period of the release, and that the flagellin gene is a suitable marker for use in the detection of bacteria in release experiments. A comparison of Ps. fluorescens SBW25 flagellin with other sequenced flagellins revealed closest homology to the flagellin of Ps. putida PRS2000. 相似文献
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Restenosis remains the main limitation of interventional cardiology. Restenosis occurs when angioplasty-induced intimal hyperplasia as well as arterial remodelling result in flow-limiting renarrowing of the arterial lumen at the angioplasty site. Intimal hyperplasia is an important candidate for gene therapy since it is related to smooth muscle cell proliferation, which is an inviting target for molecular antiproliferative strategies. To date, adenoviral vectors are, by far, the most efficient vectors to perform in vivo arterial gene transfer. These vectors, as well as others, have been recently used to demonstrate that therapeutic genes encoding cytotoxic (herpes virus thymidine kinase) or cytostatic (hypophosphorylatable Rb, Gax, endothelial nitric oxide synthase) products successfully inhibit smooth muscle cell proliferation and related intimal hyperplasia. Despite substantial progress, major technical issues, including the toxicity of first-generation adenoviral vectors, inefficient transduction of atherosclerotic arteries, and the risk of extra-arterial transfection remain to be addressed before gene therapy is applied to clinical restenosis. 相似文献