Fat substitutes promote weight gain in rats consuming high-fat diets.

The use of food products designed to mimic the sensory properties of sweet and fat while providing fewer calories has been promoted as a method for reducing food intake and body weight. However, such products may interfere with a learned relationship between the sensory properties of food and the caloric consequences of consuming those foods. In the present experiment, we examined whether use of the fat substitute, olestra, affect energy balance by comparing the effects of consuming high-fat, high-calorie potato chips to the effects of consuming potato chips that sometimes signaled high calories (using high-fat potato chips) and that sometimes signaled lower calories (using nonfat potato chips manufactured with the fat substitute olestra). Food intake, body weight gain and adiposity were greater for rats that consumed both the high-calorie chips and the low-calorie chips with olestra compared to rats that consumed consuming only the high-calorie chips, but only if animals were also consuming a chow diet that was high in fat and calories. However, rats previously exposed to both the high- and low-calorie chips exhibited increased body weight gain, food intake and adiposity when they were subsequently provided with a high fat, high calorie chow diet suggesting that experience with the chips containing olestra affected the ability to predict high calories based on the sensory properties of fat. These results extend the generality of previous findings that interfering with a predictive relationship between sensory properties of foods and calories may contribute to dysregulation of energy balance, overweight and obesity. (PsycINFO Database Record (c) 2011 APA, all rights reserved)     

A general method to recondition and reuse BIAcore sensor chips fouled with covalently immobilized protein/peptide

Of significance in the routine use of BIAcore is the cost of the sensor chips. This is particularly evident during the phase of method development of an assay where it is not unusual to expend several chips in a day in attempts to optimize immobilization conditions for a novel peptide or protein. In addition, it is accepted practice to discard a chip once its ligand binding capacity has diminished to an unacceptable level. While the high cost of sensor chips has been addressed to some degree through the recent introduction of research-grade sensor chips, we were interested in assessing the possibility of regenerating or reconditioning sensor chips in order to allow them to be reused. In particular, we concerned ourselves with regenerating sensor chips onto which peptide or protein had been immobilized. Our aim was to develop a general procedure that would allow reuse of such chips but would not decrease ligand immobilization capacity or increase nonspecific ligand adsorption properties. We present a method which employs a combination of enzymatic (Pronase E) and chemical (bromoacetic acid) treatments of used sensor chips. Regeneration requires an overnight incubation of the sensor chip ex situ so that one can continue to perform BIAcore experiments. The data demonstrate that this simple two-step procedure substantially removes immobilized proteins such as IgG, Protein G, an HIV-1 envelope glycoprotein (gp 120) and a neoglycoprotein based on bovine serum albumin, as determined by reflectance measurements and X-ray photoelectron spectroscopy.(ABSTRACT TRUNCATED AT 250 WORDS)     

Aluminum beam leaded chips,substrates and crossovers: A single metal system

A single metal system for beam-leaded chips, substrates and crossovers has been shown to be feasible using aluminum. Beams were formed on both ceramic substrates with holes tented with Riston (a sheet photoresist) and on silicon wafers by vacuum evaporation of aluminum from multiple tungsten filaments, and subsequent delineation and etching using photolithographic techniques. The chips with beams were separated from the wafer by anisotropic etching, and the tenting material removed from the ceramic by dissolution in appropriate solvents or an oxygen plasma. Beams were formed on polyimide sheet by photolithographically etching an adhesiveless laminate of aluminum on polyimide. Actual working samples have been fabricated of aluminum beam leads on ceramic and plastic substrates, aluminum beam leaded crossovers on ceramic, aluminum crossovers on plastic using multilayers and aluminum beam leaded silicon chips. Standard integrated circuit chips have been ultrasonically bonded into these substrates and the beam leaded chips have been ultrasonically bonded to an aluminum coated substrate. Environmental physical tests have shown the beam leads and crossovers to be rugged.     

Underwater Shake Table Tests on Waterfront Structures Protected with Tire Chips Cushion

A series of large-scale underwater shaking table tests was performed on a gravity type model caisson protected by a cushioning technique using tire chips (scrap tire derived recycled product). The function of the tire chips cushion is to reduce the load and restricting the permanent displacement of such waterfront retaining structures during earthquakes by exploiting the compressibility, the ductility and the energy absorbing capacity of tire chips. The seismic performance of such earthquake resistant techniques was evaluated by subjecting the soil-structure system into three different earthquake loadings (two actual earthquake records and one synthetic earthquake), and measuring the respective responses. The results demonstrated that the seismic load against the caisson quay wall could be substantially reduced using the proposed technique. In addition, the presence of the protective tire chips cushion could significantly reduce the earthquake-induced residual displacement of the caisson quay wall.     

Efficient methods of processing metal chips

The development and use of efficient methods of processing chips (particularly alloy chips) is important for solving the problems of conserving resources, improving quality of the metal that is produced, and improving the environmental situation at metallurgical plants.     

Field Evaluation of a Leachate Collection System Constructed with Scrap Tires

Landfilling costs and the potential uses of scrap tires have prompted researchers to investigate beneficial reuses. One important application is the use of tire chips as a leachate collection material in municipal solid waste landfills. Laboratory and field studies were conducted to investigate the performance of tire chips as a drainage medium in landfills. The laboratory portion of the program included a series of hydraulic conductivity and compressibility tests. Two field test cells, one with tire chips and another with gravel as the control, were constructed. The tire-chip cell was instrumented with flowmeters, thermistors, and gas collection devices to evaluate the hydraulic performance as well as the potential for spontaneous combustion. Leachate collected from the two cells was analyzed to determine if tire chips would potentially contaminate the groundwater. The results indicated that adequate drainage conditions were present within the tire-chip layer. The presence of insignificant quantities of carbon monoxide, and the lack of oxygen, and recorded low temperatures suggested that a combustion hazard was not present. The field leachate data indicated that tire chips can be safely used as part of a landfill leachate collection layer, even though it may not be suitable to place them near drinking water sources.     

钢屑中铜的测定

介绍了钢屑中铜的测定方法。火焰原子吸收法越来越多地应用于化学分析中，用其测定钢屑中的铜，操作步骤简便．准确度高，适用性强。     

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The stainless steel/iron chips core cladding bar was hot-rolled by using recycling iron scrap. The interface of the metals and the influence of rolling pass, rolling temperature, graphite additive on properties of stainless steel/iron chips core cladding bar were analyzed by optical microscope, SEM, EDS and micro hardness tester. The experimental results show that element diffusion occurs at the interface after six passes rolling and the width of diffusion zone is about 70-80??m. The Fe of carbon steel diffuses into stainless steel and the Cr, Ni, Mn of stainless steel diffuse into carbon steel which makes micro hardness of carbon steel near the interface increase obviously. The bonding strength between stainless steel and iron chips core increases with increasing of rolling passes and it is 355MPa after six passes rolling. The tensile strength and elongation of the cladding bar increase with increasing of rolling temperature and they are 470MPa and 32% at 1150??, 500MPa and 35% at 1250??. The composition of iron chips core is improved by adding graphite powder. With the increasing of the graphite in iron chips, the tensile strength of cladding bar increase, but decrease for elongation. White reticular secondary cementite is appearing when the graphite is 1. 0% and the tensile strength is up to 736. 5MPa, the elongation decrease to 16%. The tensile fracture shows brittle fracture morphology.     

Factors affecting the precision of TLD dose measurements using an automatic TLD reader

An increase in the variability of TLD dose measurements prompted a study of the precision of dose measurements with a Rialto automatic TLD reader. It was found that readings with the same chip measured using two different trays could differ by as much as 7%. In order to overcome this problem it was necessary to ensure that individual chips were correctly identified. Marking the chips with a hard graphite pencil was found to be a satisfactory method of identifying them, which, although it reduced the light output by approximately 3%, had no effect on the reproducibility of readings. Using marked chips and an individual tray for each chip, the reproducibility of a reading was reduced to a typical value of 1%. A system of quality assurance based on these findings is described.     

Rats (Rattus norvegicus) do not prefer salted solid food.

Conducted 3 studies to evaluate the ingestive responses of Sprague-Dawley rats to salt in foods and to determine whether prior exposure to salted foods influenced their intake. In Exp I, 16 Ss were given 1-hr access to salted and unsalted foods (e.g., potato chips, peanuts, soup) commonly consumed by humans in the salted form. In each choice situation, rats consumed more of the unsalted variety of solid food. In Exp II, the concentration of salt in a wider variety of foods was varied. 15 Ss were allowed a choice of a given salt concentration or the unsalted food. In no case was the salted solid food eaten in excess of the unsalted solid food, and in general, more of the unsalted solid food was eaten. In Exp III, 2 groups of 8 Ss were given exposure from weaning to either salted or unsalted potato chips for 3 mo. Exposure did not alter the Ss' relative intake of salted chips. When given a choice, more unsalted chips were consumed by both groups. Results indicate that sodium-replete Sprague-Dawley rats generally prefer unsalted solid foods to salted ones. (31 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Effectiveness of Scrap Tire Chips as Sorptive Drainage Material

Scrap tire disposal is a problem of growing concern. One solution to this problem is innovative methods for the reuse and recycling of scrap tires. Based on batch isotherm tests, scrap tire chips have been identified to be good sorbents of volatile organic compounds (VOCs) and could be used as leachate drainage layer material in solid waste landfills and in other similar applications. To demonstrate the effects of tire chips on the leachate they come in contact with in a drainage layer over a liner, large-scale tank tests simulating the drainage layer and the clay liner and also field tests were performed. Two cells were constructed in a landfill: one with scrap tire chips and the other with gravel leachate collection layer. According to the results of the large-scale tank tests and field tests, shredded tire chips have a significantly positive impact on the quality of the leachate with which they come in contact. The use of scrap tires in landfills would reduce the magnitude of the current tire disposal problem (a 1 ha landfill requires approximately 300,000 tires to fill 0.3 m of a leachate collection layer) and convert one waste into a beneficial construction material and simultaneously mitigate the problem of VOC transport from through landfill liners.     

Immediate and Time-Dependent Compression of Tire Derived Aggregate

This paper examines immediate and time-dependent compression of tire derived aggregate (TDA) and TDA-soil composites. To accommodate large particle sizes, modified experimental devices were developed and used to test tire chips and tire shreds. Immediate compression of TDA, which results almost entirely from the reduction of pore volume, increases with TDA content and tire particle size. The secant constrained modulus (Msec) of TDA defined over the stress range of 0–50?kPa varied from a low of 255?kPa (100% tire shreds) to a high of 1,320?kPa (50% tire chips). A characteristic relationship between strain and time exists for TDA and TDA composites under one-dimensional confined compression. Time-dependent deformation is well described by the modified secondary compression index (Cαε), which ranged from 0.0010 (50% tire chips) to 0.0074 (100% tire chips). Time-dependent deformation was inversely proportional to sand content, with the most significant changes resulting from the addition of 15% sand. Both applied stress and tire particle size appear to have a negligible effect on time-dependent compression of TDA. Based on the findings of this study it is recommended that practitioners assess time-dependent settlement when designing a TDA structure and if necessary incorporate design features to accommodate these settlements.     

Removal of impurities from zirconium tetrafluoride using metallic zirconium chips

The sublimation refining of zirconium tetrafluoride (ZTF) from impurities in the presence of metallic zirconium chips is studied. It is shown that, in the presence of metallic zirconium chips, the contents of aluminum, nickel, oxygen, chromium, iron, and silicon impurities in a desublimate decrease and the rate of ZTF sublimation increases. The method of refining is tested under laboratory and pilot conditions and can be recommended for commercial application.     

An electron microscopy study of chip formation

Chip formation or metal cutting is a unique large strain, high strain rate plastic deformation process. Almost all the previously reported studies of chip formation have examined the problem from the point of view of the mechanics of the deformable bodies using the mathematical theory of plasticity. This study, recognizing the heterogeneous nature of chip formation as encountered in course of machining metals, examines the problem from the metal physical or metallurgical view point. Electron microscopy studies were carried out on steel as well as nonferrous metal chips produced by shop machining conditions and compared to those chips produced by ultramicrotomy. This thin film orthogonal cutting process was employed to produce chips for microscopic examinations under well controlled and repeatable experimental conditions. The experiments carried out were designed to clarify the details of the heterogeneous plastic deformation activity occurring on the microscopic level during machining. The morphological (external surface) characteristics of the chips observed with the scanning electron microscope were correlated with the internal, dislocated structure of the chips observed by transmission electron microscopy methods. The effect of a stacking fault energy (SFE) change in an Ag-Sn alloy on chip thickness ratio(ν _t) is presented for the first time, demonstrating that this deformation process is sensitive to changes in SFE. The essentially discontinuous nature of the chip formation process observed by scanning and transmission electron microscopy is analyzed with a model involving dynamic dislocation behavior in a metal in the presence of large energy dissipation arising from plastic flow to account for the observed instability. N. Y. J. T. BLACK, formerly with the Department of Mechanical Engineering, University of Vermont, Burlington Vt.     

Attenuation of Roadway-Derived Heavy Metals by Wood Chips

Wood chips were evaluated for their ability to attenuate heavy metals in roadway runoff. Column experiments with controlled synthetic runoff composition and flow rate were used to assess effects of flow rate (intercepted sheetflow from a 3-m wide roadway section), runoff salt concentration, wood exposure to alternating wetting and drying cycles, wood aging, competition among dissolved heavy metals, and removal of particle-associated heavy metals. Overall, wood chips damped the “pulse” of copper in the synthetic runoff such that the effluent was characterized by lower concentrations (3–25% of input) over longer periods of time, but with little retention of the total copper mass. The most effective treatment was wood chips aged up to 9 months. Increased aging and chip water content reduced effluent concentrations, relative to no treatment. Flow rate had no effect on effluent concentrations. The presence of salt (>2?mS/cm) or dissolved lead (500?μg/L) in the runoff caused greater copper effluent concentrations than the no treatment case. Removal of suspended particles (and associated contaminants) was greater than 85% with an estimated capacity of 0.16?g/gwood. Field evaluation with concentrated flow to a gutter containing a wood chip treatment showed little effect on total or dissolved copper and zinc runoff concentrations and indicated that wood chips may be a source of contaminants in subsequent storm events. Applications of wood chips to treat roadway runoff would not provide a significant decrease in total maximum daily load contributions (e.g., kg/d); however, there may be some scenarios for which wood chip treatments to decrease peak storm water concentrations of dissolved heavy metals in sheetflow runoff is desirable.     

Mastoid obliteration in open cavities

The obliteration of a large or irregular mastoidectomy cavities with hard-to-control areas is a common problem for ENT surgeons. Numerous obliteration techniques have been proposed in the last 50 years. We report our experience of obliteration of mastoid cavities in 74 ears using autogenous mastoid cortical bone chips and rib cartilage. Our procedure, a partial obliteration with meatoplasty, has yielded good results. Almost 92% of these ears were dry three years after surgery. There were no cases of recurrent cholesteatoma between bone chips.     

新型焊接机控制算法研究

超声波焊接机控制软件是国内外生产微电路芯片厂家自动化流水线的不可缺少的一部分．为了提高生产微电路芯片的焊接速度，我们对超声波焊接机工业控制软件的算法进行部分优化．采用单台PC机，代替3个CPU控制3台步进电机．根据步进电机工作的特性曲线，计算出单台步进电机运行的时间控制数组，利用一个相对时间控制数组同时对3台步进电机进行控制．     

Adiabatic instability in the orthogonal cutting of steel

The reversion of Fe-18.5 Ni-0.52 C tempered martensitic steel to austenite under shear was used to study the formation of discontinuous chips by orthogonal cutting. For certain combinations of cutting speed, depth of cut, and tool rake angle, chips with bands of reverted austenite along their sheared edges were formed. Tensile tests on the same material exhibited transformed austenite on the specimen fracture surfaces for tests conducted below 200°C. Metal cutting theory predicts that continuous plastic deformation during chip formation cannot heat the material to its reversion temperature. Analysis of the machine-sample interaction before chip separation shows that adiabatic instability can occur, resulting in localized shearing and a temperature rise to at leastA _s. Only those chips which are heated during continuous deformation to temperatures between 100° and 200°C undergo adiabatic instability and reversion. Formerly National Science Foundation Trainee, Massachusetts Institute of Technology, Cambridge, Mass.     

废旧不锈钢衬底CIGS太阳能电池中回收钼的研究

废旧铜铟镓硒（CIGS）薄膜太阳能电池芯片中的钼具有很高的回收价值，提出了“氧化酸浸—亚硫酸钠除硒—萃取”的方法回收不锈钢衬底CIGS太阳能电池芯片中的钼。结果表明，采用“双氧水+硫酸”能够浸出镀层中的金属元素，并对不锈钢衬底无伤害；考察了液固比和硫酸添加量对浸出的影响，在最优工艺条件下，废芯片中主要金属元素的浸出率达到95%以上；采用“N235+异辛醇+煤油”萃取酸浸液中的钼时，硒会被同时萃取，采用“亚硫酸钠+双氧水”沉硒后，钼萃取率能够达到98%以上，同时其他金属几乎不被萃取。为不锈钢衬底铜铟镓硒薄膜太阳能电池废芯片的处理提供了一种有效的方法。     

粉末冶金烧结钢的加工性

通过烧结和在铣床上切削加工的实验，研究了添加硫化锰和氟化钙的烧结钢的加工性。结果显示，添加不同的改善切削加工性的第二相颗粒后的粉末烧结制品，其切屑形态有很大差异。添加硫化锰或氟化钙，其切屑变小，利于从孔中排出。在雾化前加入硫化锰的烧结制品，其加工性最好，1个d9．5mm的高速钢钻头可在其中钻凿532个总深13．51m的孔而毋需更换。硫化锰和氟化钙在混料过程中会发生团聚现象，降低了切削加工性。改善硫化锰和氟化钙的分布，将会改善切削加工性。