共查询到20条相似文献,搜索用时 0 毫秒
1.
Dr. Ana I. Matesanz Jorge M. Herrero Eva J. Faraco Dr. Leticia Cubo Dr. Adoracion G. Quiroga 《Chembiochem : a European journal of chemical biology》2020,21(8):1226-1232
The synthesis and characterization of three new platinum complexes, with 3,5-diacetyl-1,2,4-triazole bis(4-N-isopropylthiosemicarbazone) as a ligand, are reported. The specific conditions under which solvent coordination takes place are reported and the X-ray structure of the complex with one solvent molecule of dimethyl sulfoxide is resolved. Analysis of the reactivity of these platinum compounds aids in finding the best solution profile for biological investigations. Then, the interactions of the complexes with biological models, such as calf-thymus DNA, are studied by using UV spectroscopy and tracking the changes in electrophoretic mobility produced in the supercoiled plasmid DNA model. Initial screening of these potential antitumoral compounds indicates possible selective antitumoral action. 相似文献
2.
《广州化工》2016,(6)
采用水热法制备了Zn O以及Cu~(2+)掺杂Zn O(Cu~(2+):Zn O)纳米粉体,并将其用于光催化降解亚甲基蓝,采用X射线衍射仪(XRD)对其物相进行分析,考察了不同的表面活性剂、Cu~(2+)的掺杂量以及焙烧温度对其结构和光催化降解性能的影响。结果表明:以柠檬酸钠和十六烷基三甲基溴化铵为混合表面活性剂制备的Zn O具有最佳的光催化降解性能,其在光照65 min后,降解率达到96%。Cu~(2+)的掺杂量以及焙烧温度对Cu~(2+):Zn O样品产生较大的影响,随着Cu~(2+)的掺杂量和焙烧温度的增加,Cu~(2+):Zn O样品的光催化降解效果呈现先增加后减小的趋势,当Cu~(2+)掺杂浓度为0.01 mol、焙烧温度为600℃时,Cu~(2+):Zn O样品具有最佳的光催化降解性能,其在光照110 min后,降解率达到93%。 相似文献
3.
4.
Adhan Pilon Prof. Julia Lorenzo Sergi Rodriguez-Calado Dr. Pedro Adão Prof. Ana M. Martins Dr. Andreia Valente Dr. Luis G. Alves 《ChemMedChem》2019,14(7):770-778
New cyclam derivatives (HOCH2CH2CH2)2(PhCH2)2Cyclam and (HOCH2CH2CH2)2( PhCH2)2Cyclam, as well as their CuII and FeIII complexes, were synthesized and characterized and their stability in cellular media was assessed. The cytotoxic effect of all compounds was examined on human cervical cancer (HeLa) cells, revealing strong anticancer activity. After 24 h, only complexes with the (HOCH2CH2CH2)2( PhCH2)2Cyclam ligand are cytotoxic, whereas after incubation for 72 h all compounds show significant antiproliferative effects. Notably, compounds containing PhCH2 pendant arms on the cyclam ring revealed the most activity, with cytotoxicity values up to 12 times higher than those of cisplatin. All metal complexes seem to induce cell death through the formation of reactive oxygen species. 相似文献
5.
A hybrid sorbent material for removal of hydrogen sulfide from air was developed. The material is based on activated carbon and iron compounds obtained from waste iron(II) sulfate(VI) heptahydrate. The iron salt is deposited on the carbonaceous support and subjected to oxidation (Fe2+ to Fe3+) using atmospheric oxygen under alkaline conditions. An effect of H2O2 addition to the process on the composition of the resultant material was also examined. X-ray diffraction (XRD) analyses confirmed easy conversion of waste FeSO4·7H2O to iron oxides Fe3O4 and FeOOH. The activated carbon supporting iron oxides revealed a higher efficiency in H2S elimination from air compared to the commercial activated carbon, without any modification. 相似文献
6.
7.
通过比较水中硫化物亚甲基蓝分光光度法的吸收溶液乙酸锌-乙酸钠与氢氧化钠,发现氢氧化钠作为吸收液时标准曲线线性关系及准确度满足分析要求,且操作简便,方法准确可靠,适用于环境监测工作中硫化物的分析. 相似文献
8.
9.
《纤维素科学与技术》2020,(1):34-41
为探究有机染料废水污染的高效处理新方法,以纤维素粉为原料,利用高碘酸钠氧化、半胱氨酸接枝的方式进行巯基改性,通过扫描电子显微镜和傅里叶变换红外光谱仪等检测手段进行表征,研究了吸附时间、pH值、染料初始浓度等对亚甲基蓝吸附效果的影响。结果表明:改性后的样品比表面积明显增大,形貌出现较多细碎块状结构,且出现酰胺键特征峰;吸附过程受pH值影响较大,pH为11时吸附效果达到最佳,当初始浓度为200 mg/L时吸附平衡时间约为60 min,此时最大平衡吸附容量为192 mg/g;实验数据更符合Langmuir吸附方程和准二阶动力学模型。巯基改性纤维素材料对亚甲基蓝有较好的吸附效果,可以作为有机染料吸附剂使用。 相似文献
10.
11.
Nabel A. Negm Ahmed F. El Farargy Islam A. Mohammad Mohamad F. Zaki Manal M. Khowdiary 《Journal of surfactants and detergents》2013,16(5):767-777
A series of tannic acid Schiff base surfactants and their iron, cobalt and manganese metal complexes were synthesized and their structures were elucidated by microelemental analysis, FTIR and 1H-NMR data. The surface activities of the surfactants were increased by increasing the number of substituents, as represented from the surface tension measurements. The metal complexes showed higher critical micelle concentrations and surface tension reduction at critical micelle concentration. The antimicrobial activity in terms of inhibition zone diameter and minimum inhibitory concentrations showed increasing activity of the metal complexes over their parent compounds against Gram-positive, Gram-negative bacteria and fungi. 相似文献
12.
Binuclear rhodium(II) complexes [Rh(2)Cl(2)(mu-OOCR)(2)(N-N)(2)], [Rh(2)(mu-OOCR)(2)(N-N)(2)(H(2)O)(2)](RCOO)(2) and [Rh(2)Cl(2)(mu-OOCCH(3))(terpy)(2)](H(3)O)Cl(2).9H(2)O (R = H, Me, Bu(n), ph, PhCHOH; N-N = 2,2'-bipyridine (bpy), 1,10-phenanthroline (phen), 2,9-dimethyl-1,10-phenanthroline (dmp) and 6,7-dimethyl-2,3- di(2-pyridyl)quinoxaline (dmpq); terpy 2,2':6',2'-terpyridine) have been synthesized and their structure and properties have been studied by electronic, IR and (1)H NMR spectroscopy. Antibacterial activity of these complexes against Staphylococcus aureus and Escherichia coli has been investigated. The most active antibacterial agents against S. aureus were [Rh(2)(OOCPh)(2)(phen)(2)(H(2)O)(2)](2+), [Rh(2)(OOCPh)(2)(dmpq)(2)(H(2)O)(2)](2+), [Rh(2)(OOCBu)(2)(phen)(2)(H(2)O)(2)](2+) and [Rh(2)-(OOCBu)(2)(bpy)(2)(H(2)O)(2)](2+) which were considerably more active than the appropriate nitrogen ligands. The complexes show rather low activity against E. coli. 相似文献
13.
Gulzhian I. Dzhardimalieva Igor E. Uflyand 《Journal of Inorganic and Organometallic Polymers and Materials》2018,28(4):1305-1393
The advances and problems associated with the synthesis, properties and structure of metal complexes based on chelating polymer ligands are presented and assessed. The polymeric metal chelates (PMCs) are divided into molecular, intracomplex, macrocyclic and polynuclear types, which in turn are grouped according to the nature of the donor atoms (N,N-, N,О-, N,S-, О,О-, O,S-, S,S-, Р,Р-chelates, etc.). The main attention is focused on the similarities and differences between low and high molecular weight metal chelates, as well as the spatial organization of PMCs. The most important areas of research in the field of such compounds are highlighted. Thermal transformations of metal complexes based on chelating polymer ligands leading to the formation of nanostructured materials are considered. The bibliography includes the articles published after 2010. 相似文献
14.
Brine shrimp lethality of a new series of 16 to 26-membered macrocycles of iron(II) containing tetraaza groups and prepared by the template condensation reaction of diacarboxylic acids (malonic, succinic, glutaric or adipic) with 2,6-diaminopyridine and diethylenetriamine in 1:2:2 molar ratios have been studied. Structures and bonding of the macrocyclic complexes have been proposed based on elemental analyses, IR, electronic, X-ray and mass spectral studies. An octahedral geometry for these complexes has been proposed as the binding sites are the nitrogen atoms of the macrocycles. The formation of the complexes as [Fe(L(n))Cl(2)] has been established on the basis of the chemical composition. The complexes have also been screened against several microbes. 相似文献
15.
采用简单的溶剂热法制备了准立方体α-Fe2O3纳米材料;采用X-射线粉末衍射仪,扫描电镜和透射电镜对其进行了表征.将制备的准立方体α-Fe2O3纳米材料用于光催化降解有机染料结晶紫,并将其光催化效果与商品氧化铁对比.结果表明:准立方体α-Fe2O3纳米材料光催化性能明显优于商品氧化铁,可以作为潜在的光催化剂. 相似文献
16.
Some antifertility inhibitors of 18 to 24-membered tetraazamacrocyclic complexes of iron(II) and
manganese(II) have been synthesised by the template condensation using 1,3-phenylenediamine with
malonic acid, succinic acid, glutaric acid and adipic acid. The reaction proceed smoothly to completion. The
complexes were characterized by elemental analyses, molecular weight determinations, infrared, electronic,
magnetic moment, mössbaur and mass spectral studies. The elemental analyses are consistent with the
formation of the complexes [M(N4Ln)Cl2] (M = Fe(lI) or Mn(II)). All these complexes are stable and
monomeric in nature as indicated by the molecular weight determinations. The spectral studies confirm the
octahedral geometry around the central metal atom. The complexes have been screened in vitro against a number of fungi and bacteria to assess their growth inhibiting potential. The testicular sperm density and
testicular sperm morphology, sperm motility, density of cauda epididymal spermatozoa and fertility in
mating trials and biochemical parameters of reproductive organs have been examined and discussed. 相似文献
17.
Cationic Peptides and Their Cu(II) and Ni(II) Complexes: Coordination and Biological Characteristics
Aleksandra Kotynia Benita Wiatrak Wojciech Kamysz Damian Neubauer Paulina Jawie Aleksandra Marciniak 《International journal of molecular sciences》2021,22(21)
Antimicrobial peptides are a promising group of compounds used for the treatment of infections. In some cases, metal ions are essential to activate these molecules. Examples of metalloantibiotics are, for instance, bleomycin and dermcidin. This study is focused on three new pseudopeptides with potential biological activity. The coordination behavior of all ligands with Cu(II) and Ni(II) ions has been examined. Various analytical methods such as potentiometric titration, UV-Vis and CD spectroscopies, and mass spectrometry were used. All compounds are convenient chelators for metal ion-binding. Two of the ligands tested have histidine residues. Surprisingly, imidazole nitrogen is not involved in the coordination of the metal ion. The N-terminal amino group, Dab side chains, and amide nitrogen atoms of the peptide bonds coordinated Cu(II) and Ni(II) in all the complexes formed. The cytotoxicity of three pseudopeptides and their complexes was evaluated. Moreover, their other model allowed for assessing the attenuation of LPS-induced cytotoxicity and anti-inflammatory activities were also evaluated, the results of which revealed to be very promising. 相似文献
18.
19.
磺化聚醚砜微球制备及对亚甲蓝的吸附 总被引:1,自引:0,他引:1
采用气体三氧化硫法制备了磺化聚醚砜(SPES),并对其进行了表征。将制得的SPES用于制备吸附微球,研究了压缩空气流量对所成微球大小的影响,分析了微球内部的孔结构。对比SPES和聚醚砜(PES)2种微球对水中亚甲蓝(MB)的吸附,发现SPES微球对MB的吸附性能明显优于PES微球对MB的吸附性能。 相似文献