Approaches to antiviral chemotherapy for acute respiratory infections

This paper describes a telemedicine system for diabetic patients management, presenting its architecture, the technical solutions adopted and the methodologies on which it is based. The system, designed to provide decision support in a distributed environment, is composed of two modules, a Patient Unit and a Medical Unit, connected by telecommunication services. We outline how the two modules can interact to perform an effective monitoring and a cooperative control of glucose metabolism. In particular, we detail the data analysis tasks performed by the two units and how the results are exploited to assist patients and physicians in revising and adjusting the therapeutic protocol. We will finally describe the current prototypical implementation of the system that uses HTTP as the communication protocol and HTML pages as the graphical user interface.     

加强安全管理，实现采矿业可持续发展

加强安全生产管理,实现采矿企业可持续发展是一项复杂的系统工程。从五个方面探讨在新的经济环境下,如何充分认识安全管理工作的重要性,为企业赢得更大的发展机遇。围绕安全管理的核心要素,提出来采矿企业生产一线安全化建设的措施。     

Are frequency-induced transitions in rhythmic coordination mediated by a drop in amplitude?

The European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Study Group has adopted a modular approach to quality of life (QoL) assessment in cancer clinical trials. The core instrument (the EORTC QLQ-C30) covers a range of QoL issues relevant to a broad spectrum of patients with cancer. The QLQ-C30 is designed to be supplemented by more specific subscales ('modules') to assess aspects of QoL of particular importance to specific subgroups of patients. Since individual members of the study group were to be involved in module development, guidelines were established. The primary aim of these guidelines was to standardize the module development process in order to ensure uniformly high quality across modules. This paper gives an update of the work completed to date. First, while the guidelines proved practical for module development, producing modules that exhibit adequate levels of psychometric and cross-cultural validity, experience pointed to three areas where the guidelines required more precision. These amendments will be provided and include (1) stricter monitoring of the developmental process from within the study group, (2) the explicit requirement of involvement of the study group and (3) a more precise definition of the criteria to be fulfilled before modules are allowed to be called 'EORTC modules'. Second, an overview of the modules currently under development or available for general use is provided. These modules include those for body image, high-dose chemotherapy, leukaemia, myeloma, palliative care and the following cancers: bladder, brain, breast, colorectal, head and neck, lung, oesophageal, ophthalmic, ovarian, pancreas and prostate. Finally, the need for the coordination of efforts in module development, both from within and outside the EORTC, is discussed.     

基于强化学习的工控系统恶意软件行为检测方法

网络环境下的恶意软件严重威胁着工控系统的安全,随着目前恶意软件变种的逐渐增多,给工控系统恶意软件的检测和安全防护带来了巨大的挑战。现有的检测方法存在着自适应检测识别的智能化程度不高等局限性。针对此问题,围绕威胁工控系统网络安全的恶意软件对象,本文通过结合利用强化学习这一高级的机器学习算法,设计了一个检测应用方法框架。在实现过程中,根据恶意软件行为检测的实际需求,充分结合强化学习的序列决策和动态反馈学习等智能特征,详细讨论并设计了其中的特征提取网络、策略网络和分类网络等关键应用模块。基于恶意软件实际测试数据集进行的应用实验验证了本文方法的有效性,可为一般恶意软件行为检测提供一种智能化的决策辅助手段。      

Introduction to the Special Section on the International Classification of Functioning, Disability and Health: Implications for Rehabilitation Psychology.

This introduction to the special section of Rehabilitation Psychology on the International Classification of Functioning, Disability and Health (ICF) previews how implications for rehabilitation psychology are explored through 4 articles, each designed to build on the presentation and discussion of the prior piece: an overview of the ICF classification system; a review of contemporary applications of the ICF to clinical, government, and research uses; an update on clinical implementation efforts and related conceptual issues; and a specific application of the ICF to assistive technology service provision. The special section presents the ICF as a compelling development in the classification of functioning and health in health care service provision and, in particular, rehabilitation psychology practice. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

基于问题原型的采矿方法选择专家系统的研究

本文针对矿山的实际需要，以矿山工作人员应用对象，在充分分析矿块回采问题的基础上，提出了三种问题原型，建立了领域问题的知识库，编制了推理机，用户接口，解释，知识库管理等程序模块，形成了采矿专家系统的框架，为进一步开发奠定了基础。     

Epidemiology training for primary health care: the use of computer-assisted distance learning

The Liverpool Epidemiology Programme, based in the Liverpool School of Tropical Medicine, has designed a series of computer-based modules for use in distance learning. The purpose of this paper is to highlight the role of computers in training health workers in epidemiology in developing countries. The aim of the modules is to provide health workers with solutions to problems which they face in their everyday work. The modules are written in hypertext software for IBM compatible machines and interact with the epidemiological software Epi Info. Four modules are described: LEP-Nut which deals with nutritional surveillance, LEP-Ref which looks at the role of epidemiology within a refugee health care programme, LEP-Surv dealing with health surveillance and LEP-Rap which introduces the concept of rapid appraisal. They are also easily distributed, particularly with the development of the Internet. The modules are carefully evaluated before and after distribution. Issues related to their evaluation and subsequent revision are discussed, in particular is the content important, adequate, communicated and useful? A major advantage of computer-based learning materials is that they can be easily updated with new advancements of knowledge and experience from the field.     

Computer-Aided Healthcare Facility Management

The decision-making process in the field of health-care facility management is multifaceted and encompasses many different areas, including maintenance, performance, risk, operations, and development. Information and communications technologies are perceived as the interface that integrates these topics. The main objective of this research is to develop a decision-support system based on core parameters affecting the performance of health-care facilities. This paper presents the preliminary development of a quantitative integrated health-care facility management model, subdivided into the following three interfaces: input, reasoning evaluator and predictor, and output. The model proposes the following five modules: maintenance, performance and risk, energy and operations, business management, and development. It offers projection of maintenance costs, performance, and risk of built facilities in the health-care sector. The model hypotheses are that age, occupancy, and environment affect the maintenance of the facility. These factors are quantitatively developed and analyzed for performance-based maintenance planning, employing an occupancy coefficient and a projection of performance indicator. Simulations of the facility coefficient for different combinations of occupancy and environment reveal that the occupancy level is a major factor that causes an augmentation of more than 18% in the allocation of resources for maintenance compared with standard occupancy. Prediction of the performance score of a building is carried out using a nonlinear pattern for the structural components and linear patterns for the rest of the components.     

Object-Oriented Framework for Genetic Algorithms with Application to Space Truss Optimization

Genetic algorithms have been shown to be very effective optimization tools for a number of engineering problems. Since the genetic processes typically operate independent of the actual problem, a core genetic algorithm library consisting of all the genetic operators having an interface to a generic objective function can serve as a very useful tool for learning as well as for solving a number of practical optimization problems. This paper discusses the object-oriented design and implementation of such a core library. Object-oriented design, apart from giving a more natural representation of information, also facilitates better memory management and code reusability. Next, it is shown how classes derived from the implemented libraries can be used for the practical size optimization of large space trusses, where several constructibility aspects have been incorporated to simulate real-world design constraints. Strategies are discussed to model the chromosome and to code genetic operators to handle such constraints. Strategies are also suggested for member grouping for reducing the problem size and implementing move-limit concepts for reducing the search space adaptively in a phased manner. The implemented libraries are tested on a number of large previously fabricated space trusses, and the results are compared with previously reported values. It is concluded that genetic algorithms implemented using efficient and flexible data structures can serve as a very useful tool in engineering design and optimization.     

基于PowerBuilder的矿山设备管理系统的开发

根据新城金矿的技术环境和设备管理特点,我们利用PowerBuilder和SQL Server 2000设计和开发了该矿的矿山设备管理信息系统（MIS）,对C／S数据库规划,功能模块的设计进行了研究。并介绍了PB编程的技术关键。本系统取得良好的应用效果。     

Developing sexual health software incorporating user feedback: a British experience

This article describes an interactive prototyping model for development of four computer software modules for British youth on sexual issues. An iterative cycle of development, user review and feedback, and subsequent modification and retesting was used with approximately 150 young adults, with particular attention to presentation style, screen design, usability, relevance of material, enjoyment, and learning. The software was designed to be realistically accommodated in school settings, to be used as a reference tool by students working alone or in a group teaching situation. Feedback from youth and adults attests to the feasibility of development, implementation, and instructional usefulness. Interactive prototyping proved essential in the face of skepticism from teachers concerning young people's information needs and acceptance of a computerized educational approach.     

The impact of organizational downsizing on the job satisfaction of nurses

Professional nurses across Canada are being affected by health reform initiatives designed to deinstitutionalize the health care system. This panel study examined the impact this restructuring has had on nurses' overall job satisfaction as well as their satisfaction with various aspects of their job and work environment. The participants consisted of 345 nurses employed in 3 community hospitals in southwestern Ontario. Hospital downsizing had relatively little effect on overall job satisfaction, satisfaction with kind of work, amount of work, and physical work conditions. However, compared to before the downsizing, nurses reported a significant deterioration in satisfaction with their career future, hospital identification, supervision, and co-workers following the implementation of restructuring initiatives. We discuss the organizational and management implications of these findings and suggest ways that hospital administrators can minimize the negative effects of downsizing on nursing professionals.     

Irrigation Scheduling with Genetic Algorithms

A typical irrigation scheduling problem is one of preparing a schedule to service a group of outlets that may be serviced simultaneously. This problem has an analogy with the classical multimachine earliness/tardiness scheduling problem in operations research (OR). In previously published work, integer programming was used to solve irrigation scheduling problems; however, such scheduling problems belong to a class of combinatorial optimization problems known to be computationally demanding. This is widely reported in OR literature. Hence integer programs (IPs) can be used only to solve relatively small problems typically in a research environment where considerable computational resources and time can be allocated to solve a single schedule. For practical applications, metaheuristics such as genetic algorithms, simulated annealing, or tabu search methods need to be used. However, these need to be formulated carefully and tested thoroughly. The current research explores the potential of genetic algorithms to solve the simultaneous irrigation scheduling problem. For this purpose, two models are presented: the stream tube model and the time block model. These are formulated as genetic algorithms, which are then tested extensively, and the solution quality is compared with solutions from an IP. The suitability of these models for the simultaneous irrigation scheduling problem is reported.     

SAP-BW在安钢信息化管理中的开发应用

介绍了SAP-BW系统在安钢的开发设计、实现功能及应用效果。该系统采用三层架构,使用数据抽取策略等开发技术,完成了采购、成本、销售、库存四大模块的功能开发,为管理层提供了准确、有效的数据分析系统。     

宝钢圆方坯连铸过程机的改造实践

分析了宝钢圆方坯连铸过程机改造前存在的系统硬件老化、维护成本高,系统软件过时、扩展性不强、通信软件专属、开放性不够、软件功能欠缺、适应性不强等问题,从机型、通信、界面等方面提出了相应的系统改造技术路线。在系统集成设计方面,基于C/S架构,采用PC服务器、WINDOWS SERVER2003操作系统、ORACLE数据库、PLATURE99平台、OPC等技术;在应用功能设计方面,优化了标准管理、命令计划管理、过程跟踪和控制、实绩收集等功能模块;在画面报表设计方面,采用VISUAL STUDIO 2005中的C#和EXCEL软件,对于画面报表进行了全新设计;在模型设计方面,对二次冷却模型、切割优化模型、质量QCS模型进行了创新改进。电炉圆坯连铸机的自主集成改造不仅成功解决了原系统多项历史遗留问题,在过程监控、模型等方面也进行了多项技术创新,为公司节约了数百万元软件开发投资费用。     

视觉技术的检测系统软件设计方法

本文主要研究了烟箱缺条检测系统软件设计方法。通过对数字图像处理技术的研究,并针对现场情况,提出了图像增强、纹理分析、模板匹配、直线检测等数字图像处理算法。基于视窗系统,在Visual C＋＋开发平台上,设计了软件的体系结构,编写并调试了各功能模块。现场应用结果表明,系统满足设计要求,具有很高的检测精度和可靠性。     

CAN总线在200 kA铝电解槽上的设计与应用

采用CAN总线技术及相关的集成电路开发出基于CAN总线的全分布式控制器。控制器的逻辑单元设计为多CPU网络体系,体系内各智能化的功能模块通过CAN总线互联,实现模块间的数据交换和多CPU协同工作。在铝电解过程中的应用表明,该控制器能在强电磁干扰、高粉尘和强腐蚀性气氛的环境下稳定工作并取得了显著经济效益。     

CFRP Tendons for the Repair of Posttensioned, Unbonded Concrete Buildings

The deterioration attributable to corrosion of concrete structures reinforced with unbonded, posttensioned tendons is a costly problem. Recent research has shown composite materials such as fiber-reinforced polymers (FRP) to be suitable alternatives to steel because they provide similar strength without susceptibility to electrochemical corrosion. Carbon-FRP (CFRP) in particular has great promise for prestressed applications because it shows resistance to corrosion in environments that might be encountered in concrete and experiences less relaxation than steel. This paper outlines the testing and implementation of a posttensioned system that uses CFRP tendons to replace corroded, unbonded posttensioned steel tendons. This system was then implemented in a parking garage in downtown Toronto. To the writers’ knowledge, this is the first example of an unbonded, posttensioned tendon replacement using FRP tendons. The system used split-wedge anchors designed specifically for CFRP tendons. The dead end was anchored by directly bonding the tendon to the concrete slab. The CFRP tendon was successfully inserted in the opening created by the removal of the corroded tendon and stressed. Although the system was shown to be feasible, the current anchorage configuration results in load losses of up to 60% during the transfer. Changing the orientation of the anchor was found to reduce the load loss to an acceptable range of 1–9%.     

Integration of Municipal Infrastructure Asset Management Processes: Challenges and Solutions

Municipal infrastructure management decision making is inherently an integrated process that requires the assimilation of a multitude of data, processes, and software systems. Current work practices have resulted in significant process and data fragmentation, which have subsequently created much inefficiency that impedes the implementation of effective management strategies. There is a broad consensus in the industry that adopting integrated multidisciplinary approaches is a key requirement for implementing efficient, sustainable, and proactive asset management programs. This paper discusses the main challenges for implementing integrated municipal infrastructure management environments, and proposes specific solutions to address these challenges. The proposed solutions address the systematization and coordination of work processes, the development of centralized shared data repositories based on nonproprietary integrated data models, and the organization and integration of distributed software tools into a modular and extensible enterprise-wide software environment. The implementation of a prototype sewer management environment based on the proposed solutions is also presented.