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1.
An ABC-transporter of Arabidopsis thaliana exhibiting high sequence similarity to the human (MRP1) and yeast (YCF1) glutathione-conjugate transporters has been analysed and used to complement a cadmium-sensitive yeast mutant (DTY168) that also lacks glutathione-conjugate transport activity. Comparison of the hydrophobicity plots of this A. thaliana MRP-like protein with MRP1 and YCF1 demonstrates that the transmembrane domains are conserved, even at the N-terminus where sequence identity is low. Cadmium resistance is partially restored in the complemented ycf1 mutant, and glutathione-conjugate transport activity can be observed as well. The kinetic properties of the A. thaliana MRP-like protein (AtMRP3) are very similar to those previously described for the vacuolar glutathione-conjugate transporter of barley and mung bean. Furthermore, a hitherto undescribed ATP-dependent transport activity could be correlated with the gene product, i.e. vesicles isolated from the complemented yeast, but not from DTY168 or the wild type, take up the chlorophyll catabolite Bn-NCC-1. The results indicate that the product of the MRP-like gene of A. thaliana is capable of mediating the transport of the two different classes of compounds.  相似文献   

2.
Postconcussion symptoms are relatively common in the acute recovery period following mild traumatic brain injury. However, for a small subset of patients, self reported postconcussion symptoms continue long after injury. Many factors have been proposed to account for the presence of persistent postconcussion symptoms. The influence of personality traits has been proposed as one explanation. The purpose of this study was to examine the relation between postconcussion-like symptom reporting and personality traits in a sample of 96 healthy participants. Participants completed the British Columbia Postconcussion Symptom Inventory and the Millon Clinical Multiaxial Inventory III (MCMI–III). There was a strong positive relation between the majority of MCMI–III scales and postconcussion-like symptom reporting. Approximately half of the sample met the International Classification of Diseases-10 Criterion C symptoms for Postconcussional Syndrome. Compared with those participants who did not meet this criterion, the PCS group had significant elevations on the negativistic, depression, major depression, dysthymia, anxiety, dependent, sadistic, somatic, and borderline scales of the MCMI–III. These findings support the hypothesis that personality traits can play a contributing role in self reported postconcussion symptoms. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

3.
Examined the relationship between Diagnostic and Statistical Manual of Mental Disorders-III-Revised (DSM-III-R) personality disorders and the interpersonal circumplex and Big Five models of personality traits. 102 consecutive referrals for group therapy for personality disorders were evaluated using the Personality Disorder Examination (PDE) and the Millon Clinical Multiaxial Inventory-II (MCMI-II) personality-disorder scales. Their placement in circumplex space was assessed using the Inventory of Interpersonal Problems Circumplex Scales, whereas their standing on the Big Five traits was measured with the 50-Bipolar Self-Rating Scales (50-BSRS). The authors found that many disorders could be meaningfully located in circumplex space, whereas the use of the Big Five model led to even better placement for several disorders. Further examination of the residuals from the PDE, after the 50-BSRS scales were partialed out, indicated that the remaining common variance could also be understood in terms of the Big Five model. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

4.
Examined the relationship between the 5-factor model (FFM) of personality and the Diagnostic and Statistical Manual of Mental Disorders-III-Revised (DSM-III-R) personality disorders in a sample of 54 psychiatric outpatients. Correlations between raw scores on the NEO-Personality Inventory (NEO-PI) and the number of DSM-III—R personality disorder symptoms rated present using a semistructured interview were computed. In addition, correlations between NEO-PI scores and scores on 2 self-report personality disorder inventories were also examined to determine which results replicated across instruments. Results indicate that the FFM personality dimensions of Neuroticism, Extraversion, and Agreeableness were most apparent in the DSM-III—R conceptualizations of the personality disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

5.
Personality disorder rigidity and extremity can be geometrically defined and operationalized within the 5-factor model (FFM) of personality. A series of geometric and substantive assumptions were derived and then tested in samples of college students (N?=?1,323) and psychiatric patients (N?=?86). Normal and disordered personalities were found to coexist in a variety of regions of the FFM multivariate space. Within regions, the profiles of normal and disordered personalities were very similar in characteristic configuration but notably different in profile variability. Personality-disordered individuals tended to be located in the perimeters or outer regions of the FFM space, as indicated by their longer vector lengths. These findings generalized across 2 measures of personality disorders and across 2 measures of normal personality traits. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

6.
Two data sources—self reports and peer ratings—and two instruments—adjective factors and questionnaire scales—were used to assess the five-factor model of personality. As in a previous study of self-reports (McCrae & Costa, 1985b), adjective factors of neuroticism, extraversion, openness to experience, agreeableness–antagonism, and conscientiousness–undirectedness were identified in an analysis of 738 peer ratings of 275 adult subjects. Intraclass correlations among raters, ranging from .30 to .65, and correlations between mean peer ratings and self-reports, from .25 to .62, showed substantial cross-observer agreement on all five adjective factors. Similar results were seen in analyses of scales from the NEO Personality Inventory. Items from the adjective factors were used as guides in a discussion of the nature of the five factors. These data reinforce recent appeals for the adoption of the five-factor model in personality research and assessment. (69 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

7.
The revised 3rd edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III—R; American Psychiatric Association, 1987) distinguishes between Axis I and Axis II disorders: Axis II includes personality (and developmental) disorders, and all others are on Axis I. This distinction is often useful, but the reification of Axis I and II constructs through diagnostic criteria sets that demarcate categorically distinct entities is at times problematic. T. A. Widiger and T. Shea review the issues of differentiating personality from Axis I disorders, specifically illustrated by schizotypal and schizophrenic disorders, borderline and mood disorders, antisocial and substance use disorders, and avoidant personality from social phobia. The options for addressing their differentiation include adding exclusion criteria, shifting the placement of disorders, deleting overlapping criteria, adding differentiating criteria, and converting to a dimensional format. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

8.
This article reports a meta-analysis of personality–academic performance relationships, based on the 5-factor model, in which cumulative sample sizes ranged to over 70,000. Most analyzed studies came from the tertiary level of education, but there were similar aggregate samples from secondary and tertiary education. There was a comparatively smaller sample derived from studies at the primary level. Academic performance was found to correlate significantly with Agreeableness, Conscientiousness, and Openness. Where tested, correlations between Conscientiousness and academic performance were largely independent of intelligence. When secondary academic performance was controlled for, Conscientiousness added as much to the prediction of tertiary academic performance as did intelligence. Strong evidence was found for moderators of correlations. Academic level (primary, secondary, or tertiary), average age of participant, and the interaction between academic level and age significantly moderated correlations with academic performance. Possible explanations for these moderator effects are discussed, and recommendations for future research are provided. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

9.
The NEO Personality Inventory and representative personality scales drawn from health psychology were administered to 2 samples of male military recruits (Ns?=?296 and 502). Factor analysis of health-related personality scales revealed 3 conceptually meaningful domains. Examination of these domains and their constituent scales, with reference to the 5-factor model of personality, permits 3 general conclusions. First, most health-relevant dimensions and scales appear to be complex mixtures of broad personality domains. Second, variation in many health-related personality instruments is explained to a significant degree by the 5-factor model. Third, 2 of the 5 personality domains (i.e., conscientiousness and openness) appear to be substantially neglected in health psychology research. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

10.
11.
A distinction between ruminative and reflective types of private self-attentiveness is introduced and evaluated with respect to L. R. Goldberg's (1982) list of 1,710 English trait adjectives (Study 1), the five-factor model of personality (FFM) and A. Fenigstein, M. F. Scheier, and A. Buss's (1976) Self-Consciousness Scales (Study 2), and previously reported correlates and effects of private self-consciousness (PrSC; Studies 3 and 4). Results suggest that the PrSC scale confounds two unrelated, motivationally distinct dispositions—rumination and reflection—and that this confounding may account for the "self-absorption paradox" implicit in PrSC research findings: Higher PrSC scores are associated with more accurate and extensive self-knowledge yet higher levels of psychological distress. The potential of the FFM to provide a comprehensive framework for conceptualizing self-attentive dispositions, and to order and integrate research findings within this domain, is discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

12.
The relationship between parental attachment and eating disorder symptoms was examined for an inpatient sample of women with eating disorders (n?=?68) and for a sample of college women (n?=?162). The college women described themselves as more securely attached to parents and reported lower levels of weight and dieting preoccupation, bulimic behavior, and feelings of ineffectiveness in comparison with the eating disorder women. Canonical analysis for the combined sample suggests that the presence of an affectively positive and emotionally supportive parental relationship, in conjunction with parental fostering of autonomy, is inversely associated with weight preoccupation, bulimic behavior, and feelings of ineffectiveness. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

13.
The authors addressed the culture specificity of indigenous personality constructs, the generalizability of the 5-factor model (FFM), and the incremental validity of indigenous measures in a collectivistic culture. Filipino college students (N=508) completed 3 indigenous inventories and the Filipino version of the Revised NEO Personality Inventory (NEO-PI-R). On the basis of the factor and regression analyses, they concluded that (a) most Philippine dimensions are well encompassed by the FFM and thus may not be very culture specific; (b) a few indigenous constructs are less well accounted for by the FFM; these constructs are not unknown in Western cultures, but they may be particularly salient or composed somewhat differently in the Philippines; (c) the structure of the NEO-PI-R FFM replicates well in the Philippines; and (d) Philippine inventories add modest incremental validity beyond the FFM in predicting selected culture-relevant criteria. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

14.
Two studies were conducted that sought to (a) establish and validate a self-report method of identifying nonclinical young adults who present with significant borderline personality disorder (BPD) features and (b) evaluate the clinical correlates of this classification across a number of relevant areas of functioning. Specifically, the Personality Assessment Inventory Borderline Features Scale (PAI-BOR; L. C. Morey, 1991) was used to screen and select nonclinical participants whose scores indicated the presence of significant BPD features (B+ group) and participants whose scores indicated the relative absence of BPD features (B– group). B+ and B– participants were compared across a range of domains that are believed to be related to BPD in clinical samples (e.g., depression, personality traits, coping, Axis I disorders, interpersonal problems). Results supported the validity of this method of classification based on PAI-BOR scores and documented the level of dysfunction exhibited by the B+ participants. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

15.
This study tests the hypothesis that normal women will score higher on the more "positive" features of schizotypal personality and normal men will score higher on more "negative" schizotypal features. Two samples (n?=?393, 394) were administered the Schizotypal Personality Questionnaire, which contains subscales corresponding to the 9 schizotypal personality traits outlined in the Diagnostic and Statistical Manual of Mental Disorders-III—Revised (DSM-III—R). Women scored significantly higher on the positive subscales of Ideas of Reference and Odd Beliefs/Magical Thinking, and men scored significantly higher on the negative subscales of No Close Friends and Constricted Affect. These findings replicated from one sample to another. These results are broadly consistent with previous findings on schizotypal personality and schizophrenia. It is hypothesized that sex differences in schizophrenic symptomatology may in part reflect an exaggeration of normal sex difference in the general population. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

16.
With 575 college students, the relationship between A. Tellegen's (1985) personality model, assessed with the Multidimensional Personality Questionnaire (MPQ), and the Big Five model, operationalized by P. T. Costa and R. R. McCrae's (1985) NEO Personality Inventory, was investigated. Correlations and joint factor analyses indicated that the MPQ constructs could be well-organized under the Big Five model, and the NEO constructs could be well-organized under the Tellegen higher-order dimensions (plus Absorption). Tellegen's higher-order dimensions relate to components of the Big Five hierarchically: Negative Emotionality encompasses Big Five Neuroticism and Agreeableness, Positive Emotionality encompasses Extraversion and the surgent aspect of Conscientiousness, and Constraint encompasses the controlled aspect of Conscientiousness and much of Openness to Experience. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   

17.
Using meta-analytic tests based on 87 statistically independent samples, we investigated the relationships between the five-factor model (FFM) of personality traits and organizational citizenship behaviors in both the aggregate and specific forms, including individual-directed, organization-directed, and change-oriented citizenship. We found that Emotional Stability, Extraversion, and Openness/Intellect have incremental validity for citizenship over and above Conscientiousness and Agreeableness, 2 well-established FFM predictors of citizenship. In addition, FFM personality traits predict citizenship over and above job satisfaction. Finally, we compared the effect sizes obtained in the current meta-analysis with the comparable effect sizes predicting task performance from previous meta-analyses. As a result, we found that Conscientiousness, Emotional Stability, and Extraversion have similar magnitudes of relationships with citizenship and task performance, whereas Openness and Agreeableness have stronger relationships with citizenship than with task performance. This lends some support to the idea that personality traits are (slightly) more important determinants of citizenship than of task performance. We conclude with proposed directions for future research on the relationships between FFM personality traits and specific forms of citizenship, based on the current findings. (PsycINFO Database Record (c) 2011 APA, all rights reserved)  相似文献   

18.
OBJECTIVE: To examine the occurrence of elevated personality disorder (PD) dimensional scores in a community sample of young adults as a function of the occurrence of Axis I disorders through age 18 years. METHOD: 299 individuals who had been interviewed regarding Axis I disorders twice while in adolescence (first when 14 through 18 years of age) were carefully assessed regarding Axis I and II psychopathology at age 24. RESULTS: The prevalence of PD diagnoses was relatively low (3.8% in participants with a history of Axis I versus 1.7% in participants with no Axis I history). The occurrence of all four Axis I diagnostic categories (major depression, anxiety disorders, disruptive behavior disorders, substance use disorders) in childhood and adolescence was associated with elevated PD dimensional scores. The likelihood of elevated PD dimensional scores increased as a function of the number of Axis I disorders. Elevated PD scores were significantly associated with a negative course of major depression. CONCLUSIONS: Although the rates of PDs were low, the findings suggest a substantial degree of association between early-onset Axis I disorders and Axis II psychopathology in young adulthood. More research is needed to develop assessment and treatment recommendations addressing the early manifestations of PDs.  相似文献   

19.
Conclusions reached in previous research about the magnitude and nature of personality–performance linkages have been based almost exclusively on self-report measures of personality. The purpose of this study is to address this void in the literature by conducting a meta-analysis of the relationship between observer ratings of the five-factor model (FFM) personality traits and overall job performance. Our results show that the operational validities of FFM traits based on observer ratings are higher than those based on self-report ratings. In addition, the results show that when based on observer ratings, all FFM traits are significant predictors of overall performance. Further, observer ratings of FFM traits show meaningful incremental validity over self-reports of corresponding FFM traits in predicting overall performance, but the reverse is not true. We conclude that the validity of FFM traits in predicting overall performance is higher than previously believed, and our results underscore the importance of disentangling the validity of personality traits from the method of measurement of the traits. (PsycINFO Database Record (c) 2011 APA, all rights reserved)  相似文献   

20.
Shame, guilt, and ego development are conceptually interrelated constructs, yet their empirical relations have not yet been examined. Further, these constructs have not yet been mapped onto the widely used Five-Factor Model. In Study 1, relations were examined between these three domains within a sample of Australian university students. Two types of guilt were distinguished, Empathic Guilt (associated with Agreeableness) and Anxious Guilt (associated with Neuroticism). The relationship between Shame and Ego Level was found to be curvilinear, with Shame greatest for persons at intermediate stages of ego development. In Study 2, relations between ego development and the Five-Factor Model were further examined. Across both studies, Ego Level was best predicted from Conscientiousness among men and from Openness among women. Relations between Ego Level, proneness to shame and guilt, and the five factors were typically modest, suggesting that these represent complementary approaches to the study of personality.  相似文献   

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