陶瓷焊补技术在焦炉维修中的应用

利用陶瓷焊补技术对焦炉炭化室破损墙面进行维修。介绍了陶瓷焊补设备的组成、焊补料特性以及焊补作业的准备工作、操作过程、热工制度。实践表明，焊补后的炭化室墙面平整、光滑，挂料情况良好，推焦阻力减小，电流下降，炉墙石墨分布均匀，炉体状况得到明显的改善。     

嘉峪关长城望宇炉业有限责任公司

<正>嘉峪关市长城望宇炉业有限责任公司自主开发、研制出适用于焦炉热修补的陶瓷焊补和半干法喷补技术,其中陶瓷焊补机分别获得5项国家实用新型专利:焦炉陶瓷焊补机(专利号:03 2 57272.7)、改进的焦炉陶瓷焊补机(专利号:201120263640.3)、气动焦炉陶瓷焊补机(专利号:201120393763.9)、改进气动陶瓷焊补机(专利号:201220459485.7)和焦炉陶瓷喷焊机(专利号:201420139684.9)。     

低水准陶质焊补熔窑大碹对玻璃生产的影响

陶质焊补技术是目前玻璃窑大碹破损最有效和最可靠的修复手段,其具有不需停产和熔融结合等优点,已被玻璃生产厂家广泛接受。但低水准的陶质焊补不仅不能有效修复大碹破损,反而会对玻璃生产质量造成长期影响,给企业带来巨大经济损失。通过实际案例总结和分析低水准陶质焊补的特点及对生产的影响,提出采用致密且高耐火相的焊补材料的二次修补方案,解决了低水准陶质焊补带来的问题,提高了对陶质焊补技术的认识。     

煤气管道泄漏的带压焊补与安全措施

分析了煤气管道泄漏的原因,采用带压直接焊补的优点以及安全技术措施。指出带压直接焊补的技术措施是一种快速、有效的修复方法。     

热态维修新技术在玻璃窑炉上的应用

在玻璃窑的一个炉龄中，窑体各部位耐火材料蚀损的速度并不一致，总会先产生一些薄弱部位。及时对这些薄弱部位进行热态维修，对提高窑炉寿命是十分必要的。我国的玻璃窑炉寿命大大落后于国际先进水平，与窑炉维修手段落后有一定关系，本文叙述了采用自主开发的陶质焊补和热态喷涂等先进的热修技术修复玻璃窑蚀损严重部位的情况。实际证明可以有效延长玻璃窑的使用寿命。     

鞍钢焦炉陶瓷焊补技术的应用

1陶瓷焊补技术原理焦炉陶瓷焊补技术是20世纪70年代发展起来的焦炉热修补技术,其焊补技术原理是使用一种由耐火材料和金属粉燃料组成的干混合物,使用特定的喷枪将这种混合物喷射到需要修理的区     

焦炉火焰焊补的配料研究

焦炉火焰焊补是国内70年代发展起来的一项焦炉热补新方法。我厂1978年开始运用该技术对焦炉机侧炉头进行火焰焊补,通过多年的实际操作、摸索和技术交流,现已基本成熟,效果良好。1987年底至1988年初,火焰焊补用料为长石粉配入定量的粘土火泥,取得了突破性的进展。焊补质量的好坏主要取决于操作技巧、焊料粒度、焊料耐火度等。因内焊料一般采用长石粉,而长石粉粒径大,细度和耐火度均低,焊补后焊肉寿命短,挂料时间也短。原因是气孔率高、气孔直径大的焊肉易碎、易脱、强度差;另外,如焊肉加热不足,熔融不完全则粘结性差。     

热喷补技术在窑炉热修中的应用

介绍蓄热室马蹄焰池窑的蓄热室上部隔墙出现较大穿孔时采用的热喷补技术,主要涉及热喷补工具,热喷补材料和热喷补操作方法。     

关于铸铁蒸馏塔的焊补修复

通过对蒸馏塔最底层塔体多处纵向穿透性裂纹的现场勘查和分析，采用铸铁冷焊技术焊补修复，焊极正接，选择熔敷金属塑性好的铸308焊条，直径为3.2 mm,焊接电流为100～170 A,焊接温度严格控制在100℃以内。焊补后经表面宏观检查和煤油渗透检验，未发现存在裂纹和超标缺陷，达到了预期的焊补修复效果。     

陶瓷焊补技术在安钢的应用

文中介绍了陶瓷焊补技术对焦炉炭化室破损墙面进行维修。实践表明,焊补后的炭化室墙面平整、光滑,挂料情况良好,推焦阻力减小,电流下降,炉墙石墨分布均匀,炉体状况得到明显的改善。     

X-Ray Repair Cross Complementing Protein 1 in Base Excision Repair

X-ray Repair Cross Complementing protein 1 (XRCC1) acts as a scaffolding protein in the converging base excision repair (BER) and single strand break repair (SSBR) pathways. XRCC1 also interacts with itself and rapidly accumulates at sites of DNA damage. XRCC1 can thus mediate the assembly of large multiprotein DNA repair complexes as well as facilitate the recruitment of DNA repair proteins to sites of DNA damage. Moreover, XRCC1 is present in constitutive DNA repair complexes, some of which associate with the replication machinery. Because of the critical role of XRCC1 in DNA repair, its common variants Arg194Trp, Arg280His and Arg399Gln have been extensively studied. However, the prevalence of these variants varies strongly in different populations, and their functional influence on DNA repair and disease remains elusive. Here we present the current knowledge about the role of XRCC1 and its variants in BER and human disease/cancer.     

Repair of Protein Radicals by Antioxidants

In vivo, proteins are the main targets for radicals and other reactive species. Their reactions result in formation of amino acid radicals on the protein surface that often yield tryptophan and tyrosyl radicals or, in the presence of O₂, protein peroxyl radicals and hydroperoxides. All these species may propagate damage to biomolecules. Low molecular weight antioxidants, such as ascorbate, urate, and glutathione, are part of the defense system and function by repairing damaged proteins. We briefly review the existing knowledge about protein and amino acid radicals and their repair by antioxidants, including results of our investigations. The main question addressed is whether the antioxidants ascorbate, urate, and glutathione are able to repair amino acid radicals in model compounds and in proteins in vitro by pulse radiolysis. We show that ascorbate and urate repair tryptophan and tyrosyl radicals efficiently and inhibit proton-coupled electron transfer from tyrosine residues to tryptophan radicals in a number of proteins. In contrast, repair by glutathione is much slower. Ascorbate also rapidly reduces the peroxyl radicals of the N-acetylamide derivatives of glycine, alanine, and proline, whereas glutathione reduces peroxyl radicals in lysozyme. In vivo urate, ascorbate, and glutathione may prevent biological damage or, at least, reduce its rate, because they: (a) repair tryptophan and tyrosyl radicals in proteins and (b) reduce protein peroxyl radicals to the corresponding protein hydroperoxides. Most likely, in vivo, ascorbate and glutathione do not inhibit the reaction of C-centered amino acid radicals with O₂. Glutathione is less efficient that urate and ascorbate in repairing protein radicals; furthermore, the resulting glutathiyl radical is harmful. Ascorbate may be the more important repair agent in cells and tissues characterized by high ascorbate concentrations, such as the lens and brain; urate may be mainly responsible for repair in tissue compartments with higher urate concentrations, such as in plasma and saliva.     

水下修复材料的研究进展

水下修复技术对水下混凝土建筑物损坏开裂的修补起到极其重要的作用,而修复材料是水下修复技术中至关重要的一环。对水下修复材料的种类、组成和特点进行概述;并对一些修复材料的应用进行介绍。     

A Consensus Model of Homology-Directed Repair Initiated by CRISPR/Cas Activity

The mechanism of action of ssODN-directed gene editing has been a topic of discussion within the field of CRISPR gene editing since its inception. Multiple comparable, but distinct, pathways have been discovered for DNA repair both with and without a repair template oligonucleotide. We have previously described the ExACT pathway for oligo-driven DNA repair, which consisted of a two-step DNA synthesis-driven repair catalyzed by the simultaneous binding of the repair oligonucleotide (ssODN) upstream and downstream of the double-strand break. In order to better elucidate the mechanism of ExACT-based repair, we have challenged the assumptions of the pathway with those outlines in other similar non-ssODN-based DNA repair mechanisms. This more comprehensive iteration of the ExACT pathway better described the many different ways where DNA repair can occur in the presence of a repair oligonucleotide after CRISPR cleavage, as well as how these previously distinct pathways can overlap and lead to even more unique repair outcomes.     

Histone Displacement during Nucleotide Excision Repair

Nucleotide excision repair (NER) is an important DNA repair mechanism required for cellular resistance against UV light and toxic chemicals such as those found in tobacco smoke. In living cells, NER efficiently detects and removes DNA lesions within the large nuclear macromolecular complex called chromatin. The condensed nature of chromatin inhibits many DNA metabolizing activities, including NER. In order to promote efficient repair, detection of a lesion not only has to activate the NER pathway but also chromatin remodeling. In general, such remodeling is thought on the one hand to precede NER, thus allowing repair proteins to efficiently access DNA. On the other hand, after completion of the repair, the chromatin must be returned to its previous undamaged state. Chromatin remodeling can refer to three separate but interconnected processes, histone post-translational modifications, insertion of histone variants and histone displacement (including nucleosome sliding). Here we review current knowledge, and speculate about current unknowns, regarding those chromatin remodeling activities that physically displace histones before, during and after NER.     

Take a Break to Repair: A Dip in the World of Double-Strand Break Repair Mechanisms Pointing the Gaze on Archaea

All organisms have evolved many DNA repair pathways to counteract the different types of DNA damages. The detection of DNA damage leads to distinct cellular responses that bring about cell cycle arrest and the induction of DNA repair mechanisms. In particular, DNA double-strand breaks (DSBs) are extremely toxic for cell survival, that is why cells use specific mechanisms of DNA repair in order to maintain genome stability. The choice among the repair pathways is mainly linked to the cell cycle phases. Indeed, if it occurs in an inappropriate cellular context, it may cause genome rearrangements, giving rise to many types of human diseases, from developmental disorders to cancer. Here, we analyze the most recent remarks about the main pathways of DSB repair with the focus on homologous recombination. A thorough knowledge in DNA repair mechanisms is pivotal for identifying the most accurate treatments in human diseases.     

离心泵轴承座损坏的修复利用

在生产中,设备出现故障检修时经常会遇到备件没有或者备件不合格的问题,采用合适的修复方法就能达到修复利用的目的,并对离心泵轴承座损坏后采用阶梯套镶套的方法成功修复为例进行了叙述,设备投用后运行稳定。     

浅析中碱空气蓄热室热修技术实践

分析了造成中碱池窑蓄热室出现进、回气不畅、窑压升高、热效率下降等问题的原因。制定了不停产热修的具体技术措施并进行了实施。通过实施总结了成功经验,并找出了不足,需要改进。